Teruo Fujii

Teruo Fujii

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Teruo Fujii

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In vitro spermatogenesis in two-dimensionally spread mouse testis tissues.

Reprod Med Biol 2019 Oct 13;18(4):362-369. Epub 2019 Aug 13.

Laboratory of Biopharmaceutical and Regenerative Sciences, Institute of Molecular Medicine and Life Science Yokohama City University Association of Medical Science Yokohama Japan.

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http://dx.doi.org/10.1002/rmb2.12291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780044PMC
October 2019

Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device.

Biotechnol Prog 2019 Sep 12;35(5):e2854. Epub 2019 Jun 12.

Organ Biosystem Laboratory, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/btpr.2854DOI Listing
September 2019

A Human Induced Pluripotent Stem Cell-Derived Tissue Model of a Cerebral Tract Connecting Two Cortical Regions.

iScience 2019 Apr 18;14:301-311. Epub 2019 Apr 18.

Institute of Industrial Science, The University of Tokyo, Tokyo, Japan; Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489017PMC
April 2019

Neonatal testis growth recreated in vitro by two-dimensional organ spreading.

Biotechnol Bioeng 2018 12 29;115(12):3030-3041. Epub 2018 Sep 29.

Laboratory of Biopharmaceutical and Regenerative Sciences, Institute of Molecular Medicine and Life Science, Association of Medical Science, Yokohama City University, Yokohama, Japan.

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http://doi.wiley.com/10.1002/bit.26822
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http://dx.doi.org/10.1002/bit.26822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283240PMC
December 2018

Adenosine Triphosphate Measurement in Deep Sea Using a Microfluidic Device.

Micromachines (Basel) 2018 Jul 27;9(8). Epub 2018 Jul 27.

Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro⁻ku, 153-8505 Tokyo, Japan.

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http://www.mdpi.com/2072-666X/9/8/370
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http://dx.doi.org/10.3390/mi9080370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187658PMC
July 2018

A monolayer microfluidic device supporting mouse spermatogenesis with improved visibility.

Biochem Biophys Res Commun 2018 06 30;500(4):885-891. Epub 2018 Apr 30.

Laboratory of Biopharmaceutical and Regenerative Sciences, Institute of Molecular Medicine and Life Science, Yokohama City University Association of Medical Science, Yokohama, Kanagawa 236-0004, Japan; Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.04.180DOI Listing
June 2018

Organ/body-on-a-chip based on microfluidic technology for drug discovery.

Drug Metab Pharmacokinet 2018 Feb 13;33(1):43-48. Epub 2017 Nov 13.

International Research Center on Integrative Biomedical Systems (CIBiS), Institute of Industrial Science, The University of Tokyo, 4-6-1, Komaba, Meguro, Tokyo, 153-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.dmpk.2017.11.003DOI Listing
February 2018

Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons.

Stem Cell Reports 2017 11 26;9(5):1441-1449. Epub 2017 Oct 26.

Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831012PMC
November 2017

Pumpless microfluidic system driven by hydrostatic pressure induces and maintains mouse spermatogenesis in vitro.

Sci Rep 2017 11 13;7(1):15459. Epub 2017 Nov 13.

Laboratory of Biopharmaceutical and Regenerative Sciences, Institute of Molecular Medicine and Life Science, Yokohama City University Association of Medical Science, Yokohama, Kanagawa, 236-0004, Japan.

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http://dx.doi.org/10.1038/s41598-017-15799-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684205PMC
November 2017

Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics.

Nat Protoc 2017 Sep 24;12(9):1912-1932. Epub 2017 Aug 24.

LIMMS, CNRS-Institute of Industrial Science, UMI 2820, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/nprot.2017.092DOI Listing
September 2017

Compartmentalized embryoid body culture for induction of spatially patterned differentiation.

Biomicrofluidics 2017 Jul 2;11(4):041101. Epub 2017 Aug 2.

Center for International Research on Integrative Biomedical Systems, Institute of Industrial Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1063/1.4994989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552387PMC
July 2017

Label-free single-cell separation and imaging of cancer cells using an integrated microfluidic system.

Sci Rep 2017 04 20;7:46507. Epub 2017 Apr 20.

Dept. of Biomedical Engineering, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1038/srep46507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397835PMC
April 2017

Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment.

Genomics 2017 01 29;109(1):16-26. Epub 2016 Nov 29.

CIBIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan; CNRS UMI 2820, Laboratory for Integrated Micro Mechatronic Systems, Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1016/j.ygeno.2016.11.008DOI Listing
January 2017

Boosting functionality of synthetic DNA circuits with tailored deactivation.

Nat Commun 2016 11 15;7:13474. Epub 2016 Nov 15.

LIMMS/CNRS-IIS (UMI 2820), Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1038/ncomms13474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116077PMC
November 2016

Controlled tubulogenesis from dispersed ureteric bud-derived cells using a micropatterned gel.

J Tissue Eng Regen Med 2016 09 29;10(9):762-71. Epub 2014 Jan 29.

Renal Regeneration Laboratory, VAGLAHS at Sepulveda, North Hills, CA, USA.

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http://dx.doi.org/10.1002/term.1871DOI Listing
September 2016

Microfluidic Neurons, a New Way in Neuromorphic Engineering?

Micromachines (Basel) 2016 Aug 22;7(8). Epub 2016 Aug 22.

LIMMS (Laboratory for Integrated Micro Mechatronic Systems)/CNRS-IIS (Institute of Industrial Science), The University of Tokyo, 4-6-1 Komaba, Meguroku, 153-8505 Tokyo, Japan.

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http://www.mdpi.com/2072-666X/7/8/146
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http://dx.doi.org/10.3390/mi7080146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189925PMC
August 2016

Efficient analysis of a small number of cancer cells at the single-cell level using an electroactive double-well array.

Lab Chip 2016 07 18;16(13):2440-9. Epub 2016 May 18.

Institute of Industrial Science, The University of Tokyo, Japan.

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http://dx.doi.org/10.1039/c6lc00241bDOI Listing
July 2016

Dual stimuli-responsive smart beads that allow "on-off" manipulation of cancer cells.

Biomater Sci 2016 Jun 5;4(6):953-7. Epub 2016 May 5.

Center for International Research on Integrative Biomedical Systems (CIBiS), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan.

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http://dx.doi.org/10.1039/c6bm00186fDOI Listing
June 2016

Acoustofluidic harvesting of microalgae on a single chip.

Biomicrofluidics 2016 May 22;10(3):034119. Epub 2016 Jun 22.

Department of Chemistry, University of Tokyo , Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1063/1.4954744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920807PMC
May 2016

Long-term ex vivo maintenance of testis tissues producing fertile sperm in a microfluidic device.

Sci Rep 2016 Feb 19;6:21472. Epub 2016 Feb 19.

Laboratory of Proteomics, Institute of Molecular Medicine and Life Science, Yokohama City University Association of Medical Science, Yokohama, Kanagawa 236-0004, Japan.

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http://dx.doi.org/10.1038/srep21472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759809PMC
February 2016

Highly efficient single cell arraying by integrating acoustophoretic cell pre-concentration and dielectrophoretic cell trapping.

Lab Chip 2015 Nov;15(22):4356-63

Institute of Industrial Science, The University of Tokyo, Japan. and CREST, Japan Science and Technology Agency, Japan.

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http://dx.doi.org/10.1039/c5lc01065aDOI Listing
November 2015

A Microfluidic Diffusion Cell for Fast and Easy Percutaneous Absorption Assays.

Pharm Res 2015 Aug 28;32(8):2704-12. Epub 2015 Feb 28.

LIMMS/CNRS-IIS (UMI 2820), Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, 153-8505, Tokyo, Japan,

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http://dx.doi.org/10.1007/s11095-015-1654-xDOI Listing
August 2015

An on-chip small intestine-liver model for pharmacokinetic studies.

J Lab Autom 2015 Jun 10;20(3):265-73. Epub 2014 Nov 10.

Institute of Industrial Science, the University of Tokyo, Tokyo, Japan Core Research for Evolutionary Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan

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http://dx.doi.org/10.1177/2211068214557812DOI Listing
June 2015

A rapid method for optimizing running temperature of electrophoresis through repetitive on-chip CE operations.

Int J Mol Sci 2011 1;12(7):4271-81. Epub 2011 Jul 1.

LIMMS-CNRS/IIS (UMI2820), Institute of Industrial Science, University of Tokyo, Tokyo 153-8505, Japan; E-Mail:

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http://dx.doi.org/10.3390/ijms12074271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155350PMC
January 2015

A novel effect of parylene-based surface coating on HepG2 cell function.

Mater Sci Eng C Mater Biol Appl 2015 Jan 13;46:190-4. Epub 2014 Oct 13.

Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan; LIMMS-CNRS/IIS, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2014.10.030DOI Listing
January 2015

Integrated microfluidic systems.

Adv Biochem Eng Biotechnol 2010 ;119:179-94

LIMMS/CNRS-IIS, Institute of Industrial Science, University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo, 153-8505, Japan.

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http://link.springer.com/10.1007/10_2010_68
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http://dx.doi.org/10.1007/10_2010_68DOI Listing
June 2014

Image-based evaluations of distribution and cytotoxicity of Irinotecan (CPT-11) in a multi-compartment micro-cell coculture device.

J Biosci Bioeng 2014 Jun 25;117(6):756-62. Epub 2013 Dec 25.

Institute of Industrial Science (IIS), University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jbiosc.2013.11.019DOI Listing
June 2014

Dynamic DNA-toolbox reaction circuits: a walkthrough.

Methods 2014 May 2;67(2):234-49. Epub 2014 Feb 2.

LIMMS/CNRS UMI2820 Institute of Industrial Science, The University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 155-0085, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2014.01.015DOI Listing
May 2014

Computer-assisted design for scaling up systems based on DNA reaction networks.

J R Soc Interface 2014 Apr 22;11(93):20131167. Epub 2014 Jan 22.

Graduate School of Information Science and Technology, University of Tokyo, , Tokyo, Japan.

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http://dx.doi.org/10.1098/rsif.2013.1167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928947PMC
April 2014

Quantifying genetically inserted fluorescent protein in single iPS cells to monitor Nanog expression using electroactive microchamber arrays.

Lab Chip 2014 Feb;14(4):730-6

Institute of Industrial Science, The University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505, Japan.

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http://xlink.rsc.org/?DOI=C3LC51086G
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http://dx.doi.org/10.1039/c3lc51086gDOI Listing
February 2014

In vitro regulatory models for systems biology.

Biotechnol Adv 2013 Nov 4;31(6):789-96. Epub 2013 May 4.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1016/j.biotechadv.2013.04.008DOI Listing
November 2013

A microfluidic device for on-chip agarose microbead generation with ultralow reagent consumption.

Biomicrofluidics 2012 9;6(4):44101. Epub 2012 Oct 9.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1063/1.4758460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482248PMC
October 2013

Spatial waves in synthetic biochemical networks.

J Am Chem Soc 2013 Oct 20;135(39):14586-92. Epub 2013 Jun 20.

LIMMS/CNRS-IIS, The University of Tokyo , Komaba 4-6-2, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1021/ja403584pDOI Listing
October 2013

High-throughput and long-term observation of compartmentalized biochemical oscillators.

Chem Commun (Camb) 2013 Sep 5;49(73):8090-2. Epub 2013 Aug 5.

LIMMS/CNRS-IIS, University of Tokyo, Komaba 4-6-2 Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.1039/c3cc44323jDOI Listing
September 2013

Nucleic acids for the rational design of reaction circuits.

Curr Opin Biotechnol 2013 Aug 22;24(4):575-80. Epub 2012 Dec 22.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1016/j.copbio.2012.11.011DOI Listing
August 2013

Scaling down DNA circuits with competitive neural networks.

J R Soc Interface 2013 Aug 12;10(85):20130212. Epub 2013 Jun 12.

LIMMS/CNRS-IIS, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1098/rsif.2013.0212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043154PMC
August 2013

Ultra-high density protein spots achieved by on chip digitalized protein synthesis.

Analyst 2013 Aug 19;138(16):4663-9. Epub 2013 Jun 19.

Institute of Industrial Science, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1039/c3an00976aDOI Listing
August 2013

Importance of a diffusion-dominant small volume to activate cell-secreted soluble factor signaling in embryonic stem cell culture in microbioreactors: a mathematical model based study.

J Biosci Bioeng 2013 Jul 19;116(1):118-25. Epub 2013 Feb 19.

Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1016/j.jbiosc.2013.01.008DOI Listing
July 2013

Nano bioresearch approach by microtechnology.

Drug Discov Today 2013 Jun 9;18(11-12):552-9. Epub 2013 Feb 9.

LIMMS/CNRS-IIS, UMI 2820, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1016/j.drudis.2013.02.002DOI Listing
June 2013

Face or vase? Areal homogeneity effect.

Perception 2012 ;41(11):1392-4

Department of Psychology, Iwaki Meisei University, 5-5-1 Iino, Chuo-dai, Iwaki, Fukushima 970-8551, Japan.

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http://journals.sagepub.com/doi/10.1068/p7288
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http://dx.doi.org/10.1068/p7288DOI Listing
April 2013

Single-step CE for miniaturized and easy-to-use system.

Electrophoresis 2013 Mar;34(6):903-10

Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/elps.201200365DOI Listing
March 2013

A novel assembly technique with semi-automatic alignment for PDMS substrates.

Lab Chip 2013 Mar;13(6):1044-7

Institute of Industrial Science, The University of Tokyo, Fw-604, 4-6-1, Komaba, Tokyo, Japan.

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http://dx.doi.org/10.1039/c2lc40998dDOI Listing
March 2013

Predator-prey molecular ecosystems.

ACS Nano 2013 Jan 17;7(1):27-34. Epub 2012 Dec 17.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1021/nn3043572DOI Listing
January 2013

Direct oxygen supply with polydimethylsiloxane (PDMS) membranes induces a spontaneous organization of thick heterogeneous liver tissues from rat fetal liver cells in vitro.

Cell Transplant 2012 ;21(2-3):401-10

Laboratory for Integrated Micro-Mechatronic Systems, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.3727/096368911X605303DOI Listing
November 2012

Spatiotemporally controlled delivery of soluble factors for stem cell differentiation.

Lab Chip 2012 Nov;12(21):4508-15

Institute of Industrial Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1039/c2lc40268hDOI Listing
November 2012

Bottom-up construction of in vitro switchable memories.

Proc Natl Acad Sci U S A 2012 Nov 29;109(47):E3212-20. Epub 2012 Oct 29.

Laboratory for Integrated Micro-Mechatronic Systems, Centre National de la Recherche Scientifique/Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1073/pnas.1212069109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511151PMC
November 2012

Computing with competition in biochemical networks.

Phys Rev Lett 2012 Nov 13;109(20):208102. Epub 2012 Nov 13.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1103/PhysRevLett.109.208102DOI Listing
November 2012

Quencher-free multiplexed monitoring of DNA reaction circuits.

Nucleic Acids Res 2012 Aug 29;40(15):e118. Epub 2012 Jun 29.

LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1093/nar/gks621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424586PMC
August 2012

Modification of the glass surface property in PDMS-glass hybrid microfluidic devices.

Anal Sci 2012 ;28(1):39-44

LIMMS-CNRS/IIS, Institute of Industrial Science, University of Tokyo, Komaba, Meguro, Japan.

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http://jsac.or.jp/analsci/data/pdf/28/01/a28_0039.pdf
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http://dx.doi.org/10.2116/analsci.28.39DOI Listing
June 2012

Expanding the horizons for single-cell applications on lab-on-a-chip devices.

Methods Mol Biol 2012 ;853:199-210

JST-CREST, Institute of Industrial Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1007/978-1-61779-567-1_15DOI Listing
May 2012

Enhanced bile canaliculi formation enabling direct recovery of biliary metabolites of hepatocytes in 3D collagen gel microcavities.

Lab Chip 2012 Apr 23;12(10):1857-64. Epub 2012 Mar 23.

BEANS Laboratory, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1039/c2lc40046dDOI Listing
April 2012

Application of cell-free expression of GFP for evaluation of microsystems.

Front Biosci (Landmark Ed) 2012 Jan 1;17:1931-9. Epub 2012 Jan 1.

College of Liberal Arts and Sciences, Kitasato University, Kanagawa 252-0373, Japan.

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http://dx.doi.org/10.2741/4029DOI Listing
January 2012

Microfibrillated cellulose sheets coating oxygen-permeable PDMS membranes induce rat hepatocytes 3D aggregation into stably-attached 3D hemispheroids.

J Biomater Sci Polym Ed 2011 12;22(11):1509-22. Epub 2010 Jul 12.

Laboratory for Integrated Micro-Mechatronic Systems (LIMMS/CNRS-IIS), Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1163/092050610X513242DOI Listing
November 2011

Electroactive microwell arrays for highly efficient single-cell trapping and analysis.

Small 2011 Nov 20;7(22):3239-47. Epub 2011 Sep 20.

Institute of Industrial Science, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1002/smll.201101028DOI Listing
November 2011

Integration of a pump and an electrical sensor into a membrane-based PDMS microbioreactor for cell culture and drug testing.

Biomed Microdevices 2011 Oct;13(5):847-64

Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1007/s10544-011-9555-1DOI Listing
October 2011

A microfluidic in situ analyzer for ATP quantification in ocean environments.

Lab Chip 2011 Oct 30;11(20):3508-15. Epub 2011 Aug 30.

Institute of Industrial Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1039/c1lc20523dDOI Listing
October 2011

Reaction-diffusion phenomena in a PDMS matrix can modify its topography.

Lab Chip 2011 Sep 20;11(17):2948-54. Epub 2011 Jul 20.

Institute of Industrial Sciences, The University of Tokyo, Center for International Research on MicroMechatronics, 4-6-1-FW601, Komaba, Meguro-ku, Tokyo, 153-8505, Japan.

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http://dx.doi.org/10.1039/c1lc20218aDOI Listing
September 2011

Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues.

Biotechnol Prog 2011 Jul 31;27(4):1146-53. Epub 2011 May 31.

Institute of Industrial Science (IIS), University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/btpr.626DOI Listing
July 2011

Towards single cell heat shock response by accurate control on thermal confinement with an on-chip microwire electrode.

Lab Chip 2011 Apr 10;11(8):1513-20. Epub 2011 Mar 10.

Laboratory of Integrated Micro and Mechatronics Systems/IIS UMI CNRS 2820, Institute of Industrial Sciences, The University of Tokyo, Tokyo, Japan.

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http://xlink.rsc.org/?DOI=c0lc00701c
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http://dx.doi.org/10.1039/c0lc00701cDOI Listing
April 2011

Programming an in vitro DNA oscillator using a molecular networking strategy.

Mol Syst Biol 2011 Feb;7:466

LIMMS/CNRS-IIS, Institute of Industrial Science, University of Tokyo, Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.1038/msb.2010.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063689PMC
February 2011

Pneumatic handling of droplets on-demand on a microfluidic device for seamless processing of reaction and electrophoretic separation.

Electrophoresis 2010 Nov 22;31(22):3719-26. Epub 2010 Oct 22.

LIMMS-CNRS/IIS, Institute of Industrial Science, University of Tokyo, Tokyo, Japan.

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http://doi.wiley.com/10.1002/elps.201000295
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http://dx.doi.org/10.1002/elps.201000295DOI Listing
November 2010

Nanofluidic single-molecule sorting of DNA: a new concept in separation and analysis of biomolecules towards ultimate level performance.

Nanotechnology 2010 Oct 1;21(39):395502. Epub 2010 Sep 1.

Department of Mechanical and Control Engineering, Tokyo Institute of Technology, Tokyo, Japan.

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http://stacks.iop.org/0957-4484/21/i=39/a=395502?key=crossre
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http://dx.doi.org/10.1088/0957-4484/21/39/395502DOI Listing
October 2010

Spontaneous formation of stably-attached and 3D-organized hepatocyte aggregates on oxygen-permeable polydimethylsiloxane membranes having 3D microstructures.

Biomed Microdevices 2010 Jun;12(3):465-75

Laboratory for Integrated Micro-Mechatronic Systems (LIMMS/CNRS-IIS), Institute of Industrial Science, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan.

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http://dx.doi.org/10.1007/s10544-010-9403-8DOI Listing
June 2010

Amodal completion is not completed only behind the occluder.

Perception 2009 ;38(9):1410-2

Department of Psychology, Chuo University, 742-1 Higashinakano, Hachioji-shi, Tokyo 192-0393, Japan.

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http://journals.sagepub.com/doi/10.1068/p6478
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May 2010

Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane.

Tissue Eng Part C Methods 2010 Apr;16(2):311-8

Laboratory for Integrated Micro-Mechatronic Systems (LIMMS/CNRS-IIS), Institute of Industrial Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1089/ten.TEC.2009.0042DOI Listing
April 2010

On-chip single embryo coculture with microporous-membrane-supported endometrial cells.

IEEE Trans Nanobioscience 2009 Dec;8(4):318-24

Institute of Industrial Science, University of Tokyo, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1109/TNB.2009.2035275DOI Listing
December 2009

Biomolecular nano-flow-sensor to measure near-surface flow.

Nanoscale Res Lett 2009 Nov 14;5(2):296-301. Epub 2009 Nov 14.

Department of Mechanical and Control Engineering, Tokyo Institute of Technology, Ishikawadai 1-314, Ookayama 2-12-1 Meguro-ku, Tokyo, 152-8550, Japan.

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http://dx.doi.org/10.1007/s11671-009-9479-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894360PMC
November 2009

A micropatterned cell array with an integrated oxygen-sensitive fluorescent membrane.

Photochem Photobiol Sci 2009 Nov 30;8(11):1529-33. Epub 2009 Sep 30.

LIMMS/CNRS-IIS, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1039/b9pp00061eDOI Listing
November 2009

Low O2 metabolism of HepG2 cells cultured at high density in a 3D microstructured scaffold.

Biomed Microdevices 2009 Apr;11(2):485-94

Institute of Industrial Science, University of Tokyo, 4-6-1-FW601 Komaba Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1007/s10544-008-9254-8DOI Listing
April 2009

Millisecond denaturation dynamics of fluorescent proteins revealed by femtoliter container on micro-thermodevice.

Lab Chip 2008 Sep 29;8(9):1436-40. Epub 2008 Jul 29.

Institute of Industrial Science (IIS), The University of Tokyo, Meguro-ku, Tokyo, 153-8505, Japan.

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http://dx.doi.org/10.1039/b806749jDOI Listing
September 2008

Polymerase chain reaction-based biochemical logic gate coupled with cell-free transcription-translation of green fluorescent protein as a report gate.

Chem Commun (Camb) 2008 Aug 17(32):3771-3. Epub 2008 Jun 17.

Center for International Research on MicroMechatronics, Institute of Industrial Science, The University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505, Japan.

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http://xlink.rsc.org/?DOI=b807039c
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August 2008

A method for the design of 3D scaffolds for high-density cell attachment and determination of optimum perfusion culture conditions.

J Biomech 2008 7;41(7):1436-49. Epub 2008 Apr 7.

Institute of Industrial Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jbiomech.2008.02.025DOI Listing
July 2008

An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models.

Lab Chip 2008 May 4;8(5):741-6. Epub 2008 Apr 4.

Institute of Industrial Science, The University of Tokyo, 4-6-1-Fw604, Komaba, Meguro-ku, 153-8505, Japan.

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http://dx.doi.org/10.1039/b717091bDOI Listing
May 2008

Application of on-chip capillary electrophoresis to cell-free preparation of recombinant DNA.

Nucleic Acids Symp Ser (Oxf) 2007 (51):87-8

Center for International Research on MicroMechatronics, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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https://academic.oup.com/nass/article-lookup/doi/10.1093/nas
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http://dx.doi.org/10.1093/nass/nrm044DOI Listing
April 2008

Evaluation of cell-free protein synthesis using PDMS-based microreactor arrays.

Anal Sci 2008 Feb;24(2):243-6

Center for International Research on MicroMechatronics, Institute of Industrial Science, The University of Tokyo, Meguro, Tokyo, Japan.

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http://dx.doi.org/10.2116/analsci.24.243DOI Listing
February 2008

Enhanced maintenance and functions of rat hepatocytes induced by combination of on-site oxygenation and coculture with fibroblasts.

J Biotechnol 2008 Jan 31;133(2):253-60. Epub 2007 Aug 31.

Institute of Industrial Science (IIS), University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jbiotec.2007.08.041DOI Listing
January 2008

Active immobilization of biomolecules on a hybrid three-dimensional nanoelectrode by dielectrophoresis for single-biomolecule study.

Nanotechnology 2007 Dec 8;18(49):495503. Epub 2007 Nov 8.

Institute of Industrial Science, University of Tokyo, Fw-601, 4-6-1 Komaba Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.1088/0957-4484/18/49/495503DOI Listing
December 2007

Controlling the expression ratio of two proteins by inserting a terminator between the two genes.

Nucleic Acids Symp Ser (Oxf) 2006 (50):329-30

Center for International Research on MicroMechatronics, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1093/nass/nrl164DOI Listing
August 2007

Three-dimensional measurement and visualization of internal flow of a moving droplet using confocal micro-PIV.

Lab Chip 2007 Mar 22;7(3):338-46. Epub 2006 Dec 22.

Institute of Industrial Science, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo, Japan.

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http://dx.doi.org/10.1039/b617391hDOI Listing
March 2007

Characterization of a microfluidic dispensing system for localised stimulation of cellular networks.

Lab Chip 2006 Feb 4;6(2):218-29. Epub 2006 Jan 4.

University of Neuchâtel, Institute of Microtechnology, Rue Jaquet-Droz 1, 2000 Neuchâtel, Switzerland.

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http://dx.doi.org/10.1039/b511768bDOI Listing
February 2006

Determination of the termination efficiency of the transcription terminator using different fluorescent profiles in green fluorescent protein mutants.

Anal Sci 2005 Dec;21(12):1479-81

Biochemical Systems Laboratory, The Institute of Physical and Chemical Research (RIKEN), Saitama 351-0198, Japan.

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http://dx.doi.org/10.2116/analsci.21.1479DOI Listing
December 2005

Membrane-based PDMS microbioreactor for perfused 3D primary rat hepatocyte cultures.

Biomed Microdevices 2004 Dec;6(4):279-87

LIMMS/CNRS-IIS, University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

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http://dx.doi.org/10.1023/B:BMMD.0000048560.96140.caDOI Listing
December 2004