Tertius Hough

Tertius Hough

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Tertius Hough

Publications by authors named "Tertius Hough"

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Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism.

Endocr Connect 2020 Jan 1. Epub 2020 Jan 1.

R Thakker, NUFFIELD DEPARTMENT OF CLINICAL MEDICINE, UNIVERSITY OF OXFORD, OXFORD, OX3 7LJ, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1530/EC-19-0478DOI Listing
January 2020

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

Gene Dosage Effects at the Imprinted Gnas Cluster.

PLoS One 2013 18;8(6):e65639. Epub 2013 Jun 18.

Medical Research Council Mammalian Genetics Unit, Harwell Science and Innovation Campus, Harwell, Oxfordshire, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065639PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688811PMC
October 2017

A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress.

Dis Model Mech 2017 06 21;10(6):773-786. Epub 2017 Mar 21.

Academic Endocrine Unit, University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Headington, Oxford OX3 7LJ, UK

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http://dx.doi.org/10.1242/dmm.029488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483009PMC
June 2017

N-ethyl-N-nitrosourea-Induced Adaptor Protein 2 Sigma Subunit 1 () Mutations Establish Loss-of-Function Mice.

JBMR Plus 2017 May;1(1):3-15

Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology, and Metabolism (OCDEM), Churchill Hospital, Oxford, UK.

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http://doi.wiley.com/10.1002/jbm4.10001
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http://dx.doi.org/10.1002/jbm4.10001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824975PMC
May 2017

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).

Endocrinology 2015 Sep 8;156(9):3114-21. Epub 2015 Jun 8.

Academic Endocrine Unit (F.M.H., G.V.W., V.N.B., M.A.N., E.K., R.V.T.), Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, OX3 7LJ, United Kingdom; Medical Research Council (MRC) Mammalian Genetics Unit and Mary Lyon Centre (T.A.H., R.D.C.), MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, United Kingdom; Department of Medicine (W.D.F.), Norwich Medical School, University of East Anglia, Norwich, NR4 7TJ, United Kingdom; Laboratory of Bioorganic Chemistry (J.H.), National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892; and Albert Einstein College of Medicine (A.M.S.), Bronx, New York 10461.

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http://dx.doi.org/10.1210/en.2015-1269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541614PMC
September 2015

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

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http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.

J Proteome Res 2015 May 20;14(5):2036-45. Epub 2015 Apr 20.

‡Institute of Hepatology, Foundation for Liver Research, 69-75 Chenies Mews, London WC1E 6HX, United Kingdom.

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http://dx.doi.org/10.1021/pr501039kDOI Listing
May 2015

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.

Endocrinology 2014 Mar 3;155(3):908-22. Epub 2013 Dec 3.

Mammalian Genetics Unit (L.B., C.T.E., R.A.H., S.D.M.B., R.D.C.) and Mary Lyon Centre (C.L.S., T.A.H.), Medical Research Council Harwell, Harwell Science and Innovation Campus, Oxfordshire OX11 0RD, United Kingdom; Academic Endocrine Unit (C.T.E., M.A.N., R.A.H., F.M.H., R.V.T.), Nuffield Department of Clinical Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7LE, United Kingdom; The Mellanby Centre for Bone Research (H.E., D.L.), Department of Human Metabolism, University of Sheffield, Sheffield S10 2RX, United Kingdom; Wellcome Trust Sanger Institute (C.P.), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom; Norwich Medical School (W.D.F.), University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom; Garvan Institute of Medical Research (P.I.C.), Musculoskeletal Medicine Division, University of New South Wales, Sydney 2010, Australia; and University of Queensland Diamantina Institute (M.A.B.), Princess Alexandra Hospital, University of Queensland, Brisbane 4102, Australia.

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http://dx.doi.org/10.1210/en.2013-1247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192286PMC
March 2014

Maternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growth.

Mamm Genome 2013 Aug 10;24(7-8):276-85. Epub 2013 Jul 10.

Mammalian Genetics Unit, MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK.

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http://dx.doi.org/10.1007/s00335-013-9462-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745623PMC
August 2013

A mouse model for osseous heteroplasia.

PLoS One 2012 19;7(12):e51835. Epub 2012 Dec 19.

Medical Research Council Mammalian Genetics Unit, Medical Research Council Harwell, Oxfordshire, UK.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051835PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526487PMC
June 2013

A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.

J Bone Miner Res 2012 Feb;27(2):413-28

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/jbmr.547DOI Listing
February 2012

Establishing normal plasma and 24-hour urinary biochemistry ranges in C3H, BALB/c and C57BL/6J mice following acclimatization in metabolic cages.

Lab Anim 2010 Jul 10;44(3):218-25. Epub 2010 May 10.

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.1258/la.2010.009128DOI Listing
July 2010

Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.

J Clin Invest 2010 Jun 17;120(6):2144-55. Epub 2010 May 17.

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1172/JCI42021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877956PMC
June 2010

Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.

Endocr Relat Cancer 2009 Dec 20;16(4):1313-27. Epub 2009 Jul 20.

Academic Endocrine Unit, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1677/ERC-09-0082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439740PMC
December 2009

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract.

Mamm Genome 2009 Mar 24;20(3):140-51. Epub 2009 Jan 24.

Mammalian Genetics Unit, MRC Harwell, Oxfordshire, OX11 0RD, UK.

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http://dx.doi.org/10.1007/s00335-008-9169-yDOI Listing
March 2009

Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification.

Proc Natl Acad Sci U S A 2004 Sep 3;101(37):13566-71. Epub 2004 Sep 3.

Mammalian Genetics Unit and Mary Lyon Centre, Medical Research Council, Harwell, Oxfordshire OX11 0RD, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0405516101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518795PMC
September 2004