Teri A Manolio

Teri A Manolio

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Teri A Manolio

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Using the Data We Have: Improving Diversity in Genomic Research.

Authors:
Teri A Manolio

Am J Hum Genet 2019 Aug;105(2):233-236

National Human Genome Research Institute, Bethesda, MD 20817, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698933PMC
August 2019

Genomic medicine for undiagnosed diseases.

Lancet 2019 Aug 5;394(10197):533-540. Epub 2019 Aug 5.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/S0140-6736(19)31274-7DOI Listing
August 2019

Integrating Genomics into Healthcare: A Global Responsibility.

Am J Hum Genet 2019 Jan;104(1):13-20

Australian Genomics Health Alliance, Melbourne VIC 3052, Australia; Murdoch Children's Research Institute, Melbourne VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne VIC 3052, Australia; Global Alliance for Genomics and Health, 661 University Avenue, Suite 510, Toronto, ON M5G 0A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323624PMC
January 2019

UK Biobank debuts as a powerful resource for genomic research.

Authors:
Teri A Manolio

Nat Med 2018 12;24(12):1792-1794

Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41591-018-0276-3DOI Listing
December 2018

Prioritizing diversity in human genomics research.

Nat Rev Genet 2018 03 20;19(3):175-185. Epub 2017 Nov 20.

National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892-2152, USA.

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http://dx.doi.org/10.1038/nrg.2017.89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532668PMC
March 2018

Incorporating Whole-Genome Sequencing Into Primary Care: Falling Barriers and Next Steps.

Authors:
Teri A Manolio

Ann Intern Med 2017 08 27;167(3):204-205. Epub 2017 Jun 27.

From National Human Genome Research Institute, Bethesda, Maryland.

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http://dx.doi.org/10.7326/M17-1518DOI Listing
August 2017

In Retrospect: A decade of shared genomic associations.

Authors:
Teri A Manolio

Nature 2017 06;546(7658):360-361

Division of Genomic Medicine, the National Human Genome Research Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/546360aDOI Listing
June 2017

Implementing genomics and pharmacogenomics in the clinic: The National Human Genome Research Institute's genomic medicine portfolio.

Authors:
Teri A Manolio

Atherosclerosis 2016 10 26;253:225-236. Epub 2016 Aug 26.

Division of Genomic Medicine, National Human Genome Research Institute, 5635 Fishers Lane, Room 4113, MSC 9305, Bethesda MD, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064852PMC
http://dx.doi.org/10.1016/j.atherosclerosis.2016.08.034DOI Listing
October 2016

News from the NIH: potential contributions of the behavioral and social sciences to the precision medicine initiative.

Transl Behav Med 2015 Sep;5(3):243-6

Division of Cardiovascular Sciences of the National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 8128, Bethesda, MD 20892 USA.

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https://academic.oup.com/tbm/article/5/3/243-246/4563094
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http://dx.doi.org/10.1007/s13142-015-0320-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537462PMC
September 2015

Translational research is a key to nongeneticist physicians' genomics education.

Genet Med 2014 Dec 29;16(12):871-3. Epub 2014 May 29.

1] Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA [2] Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.

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http://dx.doi.org/10.1038/gim.2014.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697936PMC
December 2014

The growing role of professional societies in educating clinicians in genomics.

Genet Med 2014 Aug 6;16(8):571-2. Epub 2014 Feb 6.

Genomic Medicine Institute, Geisinger Medical Center, Danville, Pennsylvania, USA.

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http://dx.doi.org/10.1038/gim.2014.6DOI Listing
August 2014

Leading the way to genomic medicine.

Am J Med Genet C Semin Med Genet 2014 Mar 11;166C(1):1-7. Epub 2014 Mar 11.

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http://dx.doi.org/10.1002/ajmg.c.31384DOI Listing
March 2014

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.

Genet Epidemiol 2013 Dec 11;37(8):840-5. Epub 2013 Aug 11.

Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston, Houston, Texas.

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http://dx.doi.org/10.1002/gepi.21752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079107PMC
December 2013

Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study.

Am J Epidemiol 2013 Aug 20;178(4):534-42. Epub 2013 Jun 20.

Department of Epidemiology, Human Genetics, and Environmental Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1093/aje/kwt004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736751PMC
August 2013

Bringing genome-wide association findings into clinical use.

Authors:
Teri A Manolio

Nat Rev Genet 2013 Aug 9;14(8):549-58. Epub 2013 Jul 9.

Division of Genomic Medicine, National Human Genome Research Institute, 5635 Fishers Lane, Room 4113, MSC 9305, Rockville, Maryland 20892-9305, USA.

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http://www.nature.com/articles/nrg3523
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http://dx.doi.org/10.1038/nrg3523DOI Listing
August 2013

eXclusion: toward integrating the X chromosome in genome-wide association analyses.

Am J Hum Genet 2013 May;92(5):643-7

National Human Genome Research Institute (NHGRI), Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ajhg.2013.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644627PMC
May 2013

Leveraging the electronic health record to implement genomic medicine.

Genet Med 2013 Apr 27;15(4):270-1. Epub 2012 Sep 27.

Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/gim.2012.131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206937PMC
April 2013

Vehement agreement on new models?

Am J Epidemiol 2013 Feb 7;177(4):290-1. Epub 2013 Jan 7.

Division of Genomic Medicine, National Human Genome Research Institute, 5635 Fishers Lane, Room 4113, MSC 9305, Rockville, MD 20892-9305, USA.

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http://dx.doi.org/10.1093/aje/kws410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626056PMC
February 2013

Counterpoint: "streamlined" does not mean simple.

Am J Epidemiol 2013 Feb 7;177(4):283-4. Epub 2013 Jan 7.

National Human Genome Research Institute, 5635 Fishers Lane, Room 4113, MSC 9305, Rockville, MD 20892-9305, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626054PMC
http://dx.doi.org/10.1093/aje/kws417DOI Listing
February 2013

Consistency of genome-wide associations across major ancestral groups.

Hum Genet 2012 Jul 20;131(7):1057-71. Epub 2011 Dec 20.

Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, 45110 Ioannina, Greece.

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http://link.springer.com/content/pdf/10.1007/s00439-011-1124
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http://link.springer.com/10.1007/s00439-011-1124-4
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http://dx.doi.org/10.1007/s00439-011-1124-4DOI Listing
July 2012

The riddle of intergenic disease-associated loci.

Cell Cycle 2012 Jan 1;11(1):15-6. Epub 2012 Jan 1.

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http://dx.doi.org/10.4161/cc.11.1.18731DOI Listing
January 2012

Progression of magnetic resonance imaging-defined brain vascular disease predicts vascular events in elderly: the Cardiovascular Health Study.

Stroke 2011 Oct 4;42(10):2970-2. Epub 2011 Aug 4.

Department of Neurology, University of Washington, Box 359775, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104-2420, USA.

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http://dx.doi.org/10.1161/STROKEAHA.111.622977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183167PMC
October 2011

Assessing and managing risk when sharing aggregate genetic variant data.

Nat Rev Genet 2011 09 16;12(10):730-6. Epub 2011 Sep 16.

Translational Genomics Research Institute (TGen), Phoenix, Arizona 85004, USA.

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http://dx.doi.org/10.1038/nrg3067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349221PMC
September 2011

Genomics reaches the clinic: from basic discoveries to clinical impact.

Cell 2011 Sep;147(1):14-6

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.cell.2011.09.012DOI Listing
September 2011

Genetic architecture of cancer and other complex diseases: lessons learned and future directions.

Carcinogenesis 2011 Jul 31;32(7):945-54. Epub 2011 Mar 31.

Office of Population Genomics, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-9307, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgr056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140138PMC
July 2011

Enhancing the feasibility of large cohort studies.

JAMA 2010 Nov;304(20):2290-1

Office of Population Genomics, National Human Genome Research Institute, Bldg 31, Room 4B-09, 31 Center Dr, MSC 2154, Bethesda, MD 20892-2154, USA.

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http://dx.doi.org/10.1001/jama.2010.1686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075846PMC
November 2010

Genomewide association studies and assessment of the risk of disease.

Authors:
Teri A Manolio

N Engl J Med 2010 Jul;363(2):166-76

Office of Population Genomics, National Human Genome Research Institute, Bldg. 31, Rm. 4B-09, 31 Center Dr., MSC 2152, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1056/NEJMra0905980DOI Listing
July 2010

The HapMap and genome-wide association studies in diagnosis and therapy.

Annu Rev Med 2009 ;60:443-56

National Human Genome Research Institute, Bethesda, Maryland 20892, USA,

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http://dx.doi.org/10.1146/annurev.med.60.061907.093117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717504PMC
September 2009

External validity of the cardiovascular health study: a comparison with the Medicare population.

Med Care 2009 Aug;47(8):916-23

Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina 27715, USA.

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http://dx.doi.org/10.1097/MLR.0b013e318197b104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716425PMC
August 2009

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Proc Natl Acad Sci U S A 2009 Jun 27;106(23):9362-7. Epub 2009 May 27.

Office of Population Genomics, Genome Technology Branch, National Human Genome Research Institute, and National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD 20892, USA.

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https://www.genome.gov/pages/about/od/newsandfeatures/pnasgw
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http://www.pnas.org/content/106/23/9362.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.0903103106
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http://dx.doi.org/10.1073/pnas.0903103106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687147PMC
June 2009

Collaborative genome-wide association studies of diverse diseases: programs of the NHGRI's office of population genomics.

Authors:
Teri A Manolio

Pharmacogenomics 2009 Feb;10(2):235-41

National Human Genome Research Institute, Building 31, Room 4B-09, 31 Center Drive, MSC 2154, Bethesda, MD 20892-2154, USA.

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http://dx.doi.org/10.2217/14622416.10.2.235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714942PMC
February 2009

Cohort studies and the genetics of complex disease.

Authors:
Teri A Manolio

Nat Genet 2009 Jan;41(1):5-6

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http://dx.doi.org/10.1038/ng0109-5DOI Listing
January 2009

Variation and temporal trends in the use of diagnostic testing during hospitalization for acute myocardial infarction by age, gender, race, and geography (the Atherosclerosis Risk In Communities Study).

Am J Cardiol 2008 May 17;101(9):1219-25. Epub 2008 Mar 17.

Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.amjcard.2008.01.001DOI Listing
May 2008

A HapMap harvest of insights into the genetics of common disease.

J Clin Invest 2008 May;118(5):1590-605

National Human Genome Research Institute, 31 Center Drive, Room 4B-09, Bethesda, Maryland 20892-2154, USA.

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http://dx.doi.org/10.1172/JCI34772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2336881PMC
May 2008

Biorepositories--at the bleeding edge.

Authors:
Teri A Manolio

Int J Epidemiol 2008 Apr;37(2):231-3

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http://dx.doi.org/10.1093/ije/dym282DOI Listing
April 2008

How to interpret a genome-wide association study.

JAMA 2008 Mar;299(11):1335-44

Office of Population Genomics, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892-2154, USA.

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http://dx.doi.org/10.1001/jama.299.11.1335DOI Listing
March 2008

Study designs to enhance identification of genetic factors in healthy aging.

Authors:
Teri A Manolio

Nutr Rev 2007 Dec;65(12 Pt 2):S228-33

Office of Population Genomics at the National Human Genetics Research Institute (NHGRI), National Institutes of Health, Bethesda, Maryland 20892-2154, USA.

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http://dx.doi.org/10.1111/j.1753-4887.2007.tb00368.xDOI Listing
December 2007

Retinal microvascular signs, cognitive function, and dementia in older persons: the Cardiovascular Health Study.

Stroke 2007 Jul 24;38(7):2041-7. Epub 2007 May 24.

Centre for Eye Research Australia, University of Melbourne, East Melbourne Victoria, Australia.

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http://dx.doi.org/10.1161/STROKEAHA.107.483586DOI Listing
July 2007

Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study.

Circulation 2007 Jul 18;116(1):32-8. Epub 2007 Jun 18.

National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, MSC 1061, Bldg 10, Room B1D-416, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.645606DOI Listing
July 2007

Genes, environment, health, and disease: facing up to complexity.

Hum Hered 2007 2;63(2):63-6. Epub 2007 Feb 2.

National Human Genome Research Institute, NIH, Bethesda, MD 20892-2152, USA.

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http://dx.doi.org/10.1159/000099178DOI Listing
April 2007

Acculturation is associated with hypertension in a multiethnic sample.

Am J Hypertens 2007 Apr;20(4):354-63

Department of Medicine, University of California at San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1016/j.amjhyper.2006.09.025DOI Listing
April 2007

Intrinsic contribution of gender and ethnicity to normal ankle-brachial index values: the Multi-Ethnic Study of Atherosclerosis (MESA).

J Vasc Surg 2007 Feb;45(2):319-27

Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.jvs.2006.10.032DOI Listing
February 2007

Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: the Cardiovascular Health Study.

Am J Epidemiol 2007 Jan 13;165(1):78-84. Epub 2006 Oct 13.

Department of Neurology, University of Washington, Seattle, WA 98104-2420, USA.

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http://dx.doi.org/10.1093/aje/kwj350DOI Listing
January 2007

Taking our obligations to research participants seriously: disclosing individual results of genetic research.

Authors:
Teri A Manolio

Am J Bioeth 2006 Nov-Dec;6(6):32-4; author reply W10-2

National Human Genome Research Institute, National Institutes of Health, USA.

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http://dx.doi.org/10.1080/15265160600935993DOI Listing
January 2007

Merging and emerging cohorts: necessary but not sufficient.

Nature 2007 Jan;445(7125):259

National Human Genome Research Institute, National Institutes of Health, 31 Center Drive, Bethesda, Maryland 20892-2152, USA.

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http://dx.doi.org/10.1038/445259aDOI Listing
January 2007

Diabetes, gender, and left ventricular structure in African-Americans: the atherosclerosis risk in communities study.

Cardiovasc Ultrasound 2006 Nov 8;4:43. Epub 2006 Nov 8.

Graduate Studies Program in Cardiology, School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

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http://cardiovascularultrasound.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/1476-7120-4-43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1654185PMC
November 2006

Genes, environment and the value of prospective cohort studies.

Nat Rev Genet 2006 Oct;7(10):812-20

National Human Genome Research Institute, 31 Center Drive, Room 4B09, Bethesda, Maryland 20892-2154, USA.

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http://www.nature.com/articles/nrg1919
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http://dx.doi.org/10.1038/nrg1919DOI Listing
October 2006