Publications by authors named "Terhi Karpanen"

27Publications

The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy.

Front Immunol 2017 11;8:1718. Epub 2017 Dec 11.

Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, and K.G. Jebsen Center for Cancer Immunotherapy, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.3389/fimmu.2017.01718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732232PMC
December 2017

Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1.

Sci Rep 2017 07 7;7(1):4916. Epub 2017 Jul 7.

Translational Cancer Biology Research Program, Biomedicum Helsinki, University of Helsinki, PO Box 63, Haartmaninkatu 8, Helsinki, 00014, Finland.

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http://dx.doi.org/10.1038/s41598-017-04982-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501841PMC
July 2017

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation.

Circ Res 2017 Apr 8;120(8):1263-1275. Epub 2017 Feb 8.

From the Hubrecht Institute, KNAW and UMC Utrecht, Utrecht, the Netherlands (T.K., S.A.v.d.P., J.P.-M., G.v.d.H., M.A., S.S.-M.); Institute of Cardiovascular Organogenesis and Regeneration, Faculty of Medicine, WWU Münster, Germany (Y.P., D.S., S.S.-M.); CiM Cluster of Excellence (EXC 1003-CiM), Münster, Germany (Y.P., D.S., S.S.-M.); Max Planck Institute for Molecular Biomedicine, Münster, Germany (C.D., F.K.); Laboratory of Extracellular Matrix Biochemistry, Institute for Protein Research, Osaka University, Suita, Japan (N.M., K.S.); and Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan (N.M.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.308813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389596PMC
April 2017

T-cell receptor gene therapy--ready to go viral?

Mol Oncol 2015 Dec 20;9(10):2019-42. Epub 2015 Oct 20.

Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet and K.G. Jebsen Center for Cancer Immunotherapy, University of Oslo, Ullernchausseen 70, N-0379 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528733PMC
December 2015

CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation.

Circulation 2014 May 19;129(19):1962-71. Epub 2014 Feb 19.

Wihuri Research Institute (M.J., A.A., V.-M.L., R.K., K.A.), Translational Cancer Biology Program (M.J., S.K.J., D.T., A.A., T.H., K.A.), and Department of Biomedicine (M.J.), Biomedicum Helsinki, University of Helsinki, Helsinki, Finland; Biotechnology Programme, Spanish National Cancer Research Centre, Madrid, Spain (S.O.); Hubrecht Institute, Utrecht, The Netherlands (T.K.); and Helsinki University Central Hospital, Helsinki, Finland (K.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002779DOI Listing
May 2014

Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis.

Development 2014 Mar 12;141(6):1239-49. Epub 2014 Feb 12.

Division of Molecular Genetics and Development, Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD 4073, Australia.

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http://dx.doi.org/10.1242/dev.100495DOI Listing
March 2014

Zebrafish provides a novel model for lymphatic vascular research.

Methods Cell Biol 2011 ;105:223-38

Hubrecht Institute - KNAWand University Medical Center Utrecht, Uppsalalaan 8, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/B978-0-12-381320-6.00009-6DOI Listing
January 2012

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor.

Blood 2011 Jul 12;118(4):1154-62. Epub 2011 May 12.

Molecular/Cancer Biology Laboratory, Research Programs Unit, Institute for Molecular Medicine Finland and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1182/blood-2010-11-317800DOI Listing
July 2011

Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

Circulation 2010 Mar 15;121(12):1413-22. Epub 2010 Mar 15.

Cardiopulmonary Research Group, Transplantation Laboratory, Haartman Institute, FI-00014 University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.109.910703DOI Listing
March 2010

VEGF-D: a modifier of embryonic lymphangiogenesis.

Blood 2008 Sep;112(5):1547-8

Hubrecht Institute, University of Helsinki.

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http://dx.doi.org/10.1182/blood-2008-06-159343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518870PMC
September 2008

Molecular biology and pathology of lymphangiogenesis.

Annu Rev Pathol 2008 ;3:367-97

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and Haartman Institute, University of Helsinki and Helsinki University Central Hospital, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1146/annurev.pathmechdis.3.121806.151515DOI Listing
May 2008

Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein.

Circ Res 2007 May 3;100(10):1460-7. Epub 2007 May 3.

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1161/01.RES.0000269042.58594.f6DOI Listing
May 2007

Functional interaction of VEGF-C and VEGF-D with neuropilin receptors.

FASEB J 2006 Jul;20(9):1462-72

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, P.O.B. 63, FI-00014 University of Helsinki, Helsinki, Finland.

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http://www.fasebj.org/doi/10.1096/fj.05-5646com
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http://dx.doi.org/10.1096/fj.05-5646comDOI Listing
July 2006

Vascular endothelial growth factor (VEGF)/VEGF-C mosaic molecules reveal specificity determinants and feature novel receptor binding patterns.

J Biol Chem 2006 Apr 27;281(17):12187-95. Epub 2006 Feb 27.

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, P.O. Box 63 (Haartmaninkatu 8), University of Helsinki, Helsinki 00014, Finland.

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http://dx.doi.org/10.1074/jbc.M511593200DOI Listing
April 2006

Regulation of lymphangiogenesis--from cell fate determination to vessel remodeling.

Exp Cell Res 2006 Mar 15;312(5):575-83. Epub 2005 Dec 15.

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki, Haartman Institute and Helsinki University Central Hospital, University of Helsinki, PO Box 63 (Haartmaninkatu 8), 00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.yexcr.2005.10.034DOI Listing
March 2006

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis.

Nat Med 2004 Sep 22;10(9):974-81. Epub 2004 Aug 22.

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and Helsinki University Central Hospital, University of Helsinki, Haartmaninkatu 8, P.O.B. 63, 00014 Helsinki, Finland.

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http://www.nature.com/articles/nm1094
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http://dx.doi.org/10.1038/nm1094DOI Listing
September 2004

PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.

Blood 2004 Nov 22;104(10):3198-204. Epub 2004 Jul 22.

Molecular/Cancer Biology Laboratory, Ludwig Institute for Cancer Research, Helsinki University, Finland.

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http://dx.doi.org/10.1182/blood-2004-04-1485DOI Listing
November 2004

Role of lymphangiogenic factors in tumor metastasis.

Biochim Biophys Acta 2004 Mar;1654(1):3-12

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Biomedicum Helsinki and Helsinki University Central Hospital, University of Helsinki, POB 63 (Haartmaninkatu 8), 00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.bbcan.2003.07.003DOI Listing
March 2004

Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

J Natl Cancer Inst 2002 Jun;94(11):819-25

Molecular/Cancer Biology Laboratory and Ludwig Institute for Cancer Research, Haartman Institute and Helsinki University Central Hospital, Biomedicum Helsinki, University of Helsinki, Finland.

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http://dx.doi.org/10.1093/jnci/94.11.819DOI Listing
June 2002

VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors.

Int J Cancer 2002 Apr;98(6):946-51

Department of Anatomy, Institute of Biomedicine and MediCity Research Laboratory, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1002/ijc.10283DOI Listing
April 2002