Publications by authors named "Teresa Risopatron Knutsen"

3 Publications

  • Page 1 of 1

Health Behavior and Lifestyle Trends among Platelet Donors: Results from a Questionnaire-Based Survey in Norway.

Biomed Res Int 2021 22;2021:8891885. Epub 2021 Mar 22.

Department of Immunology and Transfusion Medicine, Akershus University Hospital, Norway.

Background: Blood donors are on average healthier than the general population, a phenomenon known as the "healthy donor effect." Earlier studies have also pointed to healthier behaviors among whole blood donors than the general population. This study is aimed at assessing the prevalence of four healthy behaviors (sufficient physical activity, avoiding cigarette smoking, low to moderate alcohol use, and maintaining a healthy weight) among platelet donors and to compare the results with those in the general population of similar ages.

Methods: Eighty-six platelet donors were asked to complete a questionnaire designed to assess physical activity, smoking, and alcohol use. Sociodemographic information including gender, age, and education was also collected from all participants. Chi-square statistics and logistic regression were used in statistical analysis.

Results: The mean age of the study donors was 51 years, 56% were female. Most were employed (90%), and 48% hold a bachelor's or higher degree. The prevalence of healthy behaviors differed by education gradients but not by gender and age. About 49% of the donors met the weekly physical activity recommendations, less than 5% were daily smokers, and~26% were classified as more frequent drinkers (≥1 to ≤5 times per week). The corresponding percentages for the general population were, respectively, 33%, 13%, and 35%. The prevalence of overweight and obesity, as assessed by body mass index (BMI), among donors were 50% and 29%, respectively, much higher than the current prevalence of overweight and obesity of 37% and 19%, respectively, among adults in the general population.

Conclusions: The individual health behaviors of the majority of the study population could be characterized by a relatively high level of physical activity, low prevalence of daily smoking, and moderate alcohol drinking. The above-average overweight/obesity prevalence among platelet donors in this cohort is of concern because of the potential serious health consequences and it warrants further reflection.
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May 2021

Relationship of Baseline Hemoglobin Level with Serum Ferritin, Postphlebotomy Hemoglobin Changes, and Phlebotomy Requirements among HFE C282Y Homozygotes.

Biomed Res Int 2015 26;2015:241784. Epub 2015 Aug 26.

Department of Immunology and Transfusion Medicine, Akershus University Hospital, University of Oslo, Norway.

Objectives. We aimed to examine whether baseline hemoglobin levels in C282Y-homozygous patients are related to the degree of serum ferritin (SF) elevation and whether patients with different baseline hemoglobin have different phlebotomy requirements. Methods. A total of 196 patients (124 males and 72 females) who had undergone therapeutic phlebotomy and had SF and both pre- and posttreatment hemoglobin values were included in the study. Results. Bivariate correlation analysis suggested that baseline SF explains approximately 6 to 7% of the variation in baseline hemoglobin. The results also showed that males who had higher (≥150 g/L) baseline hemoglobin levels had a significantly greater reduction in their posttreatment hemoglobin despite requiring fewer phlebotomies to achieve iron depletion than those who had lower (<150 g/L) baseline hemoglobin, regardless of whether baseline SF was below or above 1000 µg/L. There were no significant differences between hemoglobin subgroups regarding baseline and treatment characteristics, except for transferrin saturation between male subgroups with SF above 1000 µg/L. Similar differences were observed when females with higher (≥138 g/L) baseline hemoglobin were compared with those with lower (<138 g/L) baseline hemoglobin. Conclusion. Dividing C282Y-homozygous patients into just two subgroups according to the degree of baseline SF elevation may obscure important subgroup variations.
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June 2016

Implementation of ISBT 128, a quality system, a standardized bar code labeling of blood products worldwide, electronic transfusion pathway: four years of experience in Norway.

Transfusion 2007 Sep;47(9):1674-8

Department of Immunology and Transfusion Medicine, Akershus University Hospital, Lørenskog, Norway.

Background: In today's world of multinational disaster relief programs, blood collected and processed in one country may be used in another. A great deal of important information is carried by a blood product label. Given the concerns about safety and traceability, it is important to use globally unique blood product coding and labeling system.

Study Design And Methods: In 1994 the International Society of Blood Transfusion (ISBT) gave a group, ICCBBA (formerly called International Council for Commonality in Blood Banking Automation), the responsibility for implementing a new, safe international system for coding and labeling blood products. This new system is based on 128 bar code symbology and is called ISBT 128. This study describes how ISBT 128 was implemented in blood banks in Norway.

Results: As soon as a couple of the most central blood banks implemented the system and started to use it in 2001, they found that it was much easier to handle than their old systems. There were two different software systems being used that were ISBT 128-compliant. The facilities started to export and import blood products to each other. The "foreign" blood products were easily scanned into "own" inventory. They were reluctant to order blood products from blood banks not using ISBT 128. Because of the success in the Department of Immunology and Transfusion Medicine at the University Hospital of Akershus and some other blood banks in Norway, the Norwegian Health Authorities advised all the blood banks to implement ISBT 128.

Conclusion: The use of ISBT 128 has been a success from the very beginning.
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September 2007