Publications by authors named "Teresa Inkster"

12 Publications

  • Page 1 of 1

Genomic epidemiology of a case cluster in Glasgow, Scotland, 2018.

Microb Genom 2021 Mar 23;7(3). Epub 2021 Feb 23.

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

In 2018, a cluster of two cases of cryptococcosis occurred at the Queen Elizabeth University Hospital (QEUH) in Glasgow, Scotland (UK). It was postulated that these cases may have been linked to pigeon droppings found on the hospital site, given there have been previous reports of associated with pigeon guano. Although some samples of pigeon guano taken from the site yielded culturable yeast from genera related to , they have since been classified as or spp., and no isolates of were recovered from either the guano or subsequent widespread air sampling. In an attempt to further elucidate any possible shared source of the clinical isolates, we used whole-genome sequencing and phylogenetic analysis to examine the relationship of the two isolates from the QEUH cases, along with two isolates from sporadic cases treated at a different Glasgow hospital earlier in 2018. Our work demonstrated that these four clinical isolates were not clonally related; while all isolates were from the VNI global lineage and of the same mating type (MATĪ±), the genotypes of the two QEUH isolates were separated by 1885 base changes and belonged to different sub-lineages, recently described as the intercontinental sub-clades VNIa-93 and VNIa-5. In contrast, one of the two sporadic 2018 clinical isolates was determined to belong to the VNIb sub-lineage and the other classified as a VNIV/VNI hybrid. Our work demonstrated that the two 2018 QEUH isolates and the two prior clinical isolates were all genetically distinct. It was not possible to determine whether the QEUH genotypes stemmed from independent sources or from the same source, i.e. pigeons carrying different genotypes, but it should be noted that whilst members of allied genera within the were isolated from the hospital environment, there were no environmental isolations of .
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http://dx.doi.org/10.1099/mgen.0.000537DOI Listing
March 2021

Duty of candour and communication during an infection control incident in a paediatric ward of a Scottish hospital: how can we do better?

J Med Ethics 2021 Feb 16. Epub 2021 Feb 16.

Parent and family representative on Communication & Engagement Sub-Group, Family representative on Oversight Board convened in furtherance of Escalation to Stage 4 by Scottish Government, Coventry University, Glasgow, UK.

Duty of candour legislation was introduced in Scotland in 2018. However, literature and experience of duty of candour when applied to infection control incidents/outbreaks is scarce. We describe clinician and parental perspectives with regard to duty of candour and communication during a significant infection control incident in a haemato-oncology ward of a children's hospital. Based on the learning from this incident, we make recommendations for duty of candour and communication to patients and families during future infection control incidents. These include the need to consider a crisis management approach, the importance of not underestimating psychological harm in incidents of a prolonged duration and embedding the existing legislation pertaining to the rights of the child.
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http://dx.doi.org/10.1136/medethics-2020-106862DOI Listing
February 2021

Colonisation with toxigenic Corynebacterium diphtheriae in a Scottish burns patient, June 2015.

Euro Surveill 2015 ;20(49)

Royal Alexandra Hospital, Glasgow, Scotland.

On 12 June 2015, Corynebacterium diphtheriae was identified in a skin swab from a burns patient in Scotland. The isolate was confirmed to be genotypically and phenotypically toxigenic. Multilocus sequence typing of three patient isolates yielded sequence type ST 125. The patient was clinically well. We summarise findings of this case, and results of close contact identification and screening: 12 family and close contacts and 32 hospital staff have been found negative for C. diphtheriae.
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http://dx.doi.org/10.2807/1560-7917.ES.2015.20.49.30088DOI Listing
May 2016

Non-toxigenic Vibrio cholerae bacteraemia: case report and review of the literature.

J Med Microbiol 2013 Sep 30;62(Pt 9):1357-1359. Epub 2013 May 30.

Health Protection Scotland, Glasgow, UK.

Vibrio cholerae is a serious public health problem worldwide, but in the UK, V. cholerae infections are rare. Here, we report a case of V. cholerae bacteraemia in an elderly patient. To our knowledge, this is the first non-travel-related V cholerae bacteraemia in the UK.
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http://dx.doi.org/10.1099/jmm.0.060400-0DOI Listing
September 2013

A syphilis-positive organ donor -- management of the cardiac transplant recipient: a case report and review of the literature.

Sex Transm Dis 2012 Jun;39(6):485-6

From the Microbiology Department, Glasgow Royal Infirmary, Glasgow, United Kingdom.

Syphilis as a public health problem has not been resolved. Because donor organs are scarce, Treponema pallidum seropositivity is no longer considered a contraindication to transplant. However, there is little guidance on the management and monitoring on the recipient of organs from patients with syphilis. We present a case of a patient successfully transplanted with a heart from a seropositive donor and a review of the literature.
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http://dx.doi.org/10.1097/OLQ.0b013e318249db35DOI Listing
June 2012

Septic arthritis following anterior cruciate ligament reconstruction secondary to Clostridium sporogenes; a rare clinical pathogen.

J Clin Pathol 2011 Sep 28;64(9):820-1. Epub 2011 Jan 28.

Department of Microbiology, Golden Jubilee National Hospital, Clydebank, Glasgow, UK.

A case of septic arthritis post anterior cruciate ligament reconstruction secondary to Clostridium sporogenes is described in a 19-year-old man. C sporogenes is a rare clinical pathogen and this is believed to be the first case of septic arthritis due to the organism. The patient responded to arthroscopic washout, synovectomy and combination antibiotic therapy. A review of the literature is also presented.
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http://dx.doi.org/10.1136/jcp.2010.084434DOI Listing
September 2011

Diagnosis of pneumococcal pericarditis using antigen testing and polymerase chain reaction.

Scand J Infect Dis 2010 Oct;42(10):791-3

Department of Microbiology, Golden Jubilee Hospital, Clydebank, Glasgow, Scotland.

Following the advent of antibiotics, pneumococcal pericarditis has become a rare clinical diagnosis. We discuss 2 cases of pneumococcal pericarditis that were preceded by community-acquired pneumonia. Cultures were negative in both patients and the diagnosis was made by antigen testing and polymerase chain reaction (PCR) of the pericardial fluid. PCR or antigen testing of pericardial fluid for pneumococci should be considered in patients with a typical history, particularly when culture-negative and with a history of prior antibiotics.
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http://dx.doi.org/10.3109/00365548.2010.486002DOI Listing
October 2010

Antibiotic prophylaxis for cardiac surgery: a shift away from traditional cephalosporins?

Authors:
Teresa Inkster

J Cardiothorac Vasc Anesth 2009 Dec 12;23(6):933-5. Epub 2009 Feb 12.

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http://dx.doi.org/10.1053/j.jvca.2008.12.013DOI Listing
December 2009