Teppei Morikawa

Teppei Morikawa

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Graduate School of MedicineJapan

Publications

Clinical significance of mucinous components in rectal cancer after preoperative chemoradiotherapy.
Surg Today 2017 Jun 22;47(6):697-704. Epub 2016 Sep 22.
Department of Surgical Oncology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers.
Int J Cancer 2017 Jun 28;140(12):2648-2656. Epub 2017 Mar 28.
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
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Different Impacts of Preoperative Radiotherapy and Chemoradiotherapy on Oncological Outcomes in Patients with Stages II and III Lower Rectal Cancer: A Propensity Score Analysis.
Dig Surg 2017 Jun 21. Epub 2017 Jun 21.
Department of Surgical Oncology, The University of Tokyo Hospital, Tokyo, Japan.
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Prediction of Pathological Complete Response Using Endoscopic Findings and Outcomes of Patients Who Underwent Watchful Waiting After Chemoradiotherapy for Rectal Cancer.
Dis Colon Rectum 2017 Apr;60(4):368-375
1 Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan 2 Department of Pathology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
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Thoracic intradural extramedullary lesions causing progressive myelopathy as an initial manifestation of granulomatosis with polyangiitis: a case report and review of literature.
J Spinal Cord Med 2017 Jan 22;40(1):122-125. Epub 2016 Apr 22.
a Department of Orthopedic Surgery , The University of Tokyo Hospital , Tokyo , Japan.
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Regular Aspirin Use Associates With Lower Risk of Colorectal Cancers With Low Numbers of Tumor-Infiltrating Lymphocytes.
Gastroenterology 2016 Nov 27;151(5):879-892.e4. Epub 2016 Jul 27.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:
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Impact of Gleason pattern 5 including tertiary pattern 5 on outcomes of salvage treatment for biochemical recurrence in pT2-3N0M0 prostate cancer.
Int J Clin Oncol 2016 Oct 20;21(5):975-980. Epub 2016 Apr 20.
Department of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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Low density of CD204-positive M2-type tumor-associated macrophages in Epstein-Barr virus-associated gastric cancer: a clinicopathologic study with digital image analysis.
Hum Pathol 2016 Oct 21;56:74-80. Epub 2016 Jun 21.
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan. Electronic address:
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Loss of YAP1 defines neuroendocrine differentiation of lung tumors.
Cancer Sci 2016 Oct 9;107(10):1527-1538. Epub 2016 Sep 9.
Molecular Pathology Laboratory, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
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MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival.
Clin Cancer Res 2016 Aug 8;22(15):3841-8. Epub 2016 Mar 8.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Division of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
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Optimal timing of salvage radiotherapy for biochemical recurrence after radical prostatectomy: is ultra-early salvage radiotherapy beneficial?
Radiat Oncol 2016 Jul 30;11:102. Epub 2016 Jul 30.
Department of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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Survival Benefit of Exercise Differs by Tumor IRS1 Expression Status in Colorectal Cancer.
Ann Surg Oncol 2016 Mar 17;23(3):908-17. Epub 2015 Nov 17.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis.
Br J Cancer 2016 Jan 7;114(2):199-206. Epub 2016 Jan 7.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue M420, Boston, MA 02215, USA.
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Maxillary carcinosarcoma: Identification of a novel MET mutation in both carcinomatous and sarcomatous components through next generation sequencing.
Head Neck 2015 Dec 6;37(12):E179-85. Epub 2015 Jul 6.
Department of Otolaryngology, Head and Neck Surgery, University of Tokyo Hospital, Tokyo, Japan.
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Preoperative evaluation of renal cell carcinoma by using 18F-FDG PET/CT.
Clin Nucl Med 2015 Dec;40(12):936-40
From the *Division of Nuclear Medicine, Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, †Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, and ‡Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.
Am J Pathol 2015 Nov 9;185(11):2923-38. Epub 2015 Oct 9.
Department of Molecular Preventive Medicine, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan; Japan Science and Technology Agency, Core Research for Evolutional Science and Technology (CREST), Tokyo, Japan. Electronic address:
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Hunner-Type (Classic) Interstitial Cystitis: A Distinct Inflammatory Disorder Characterized by Pancystitis, with Frequent Expansion of Clonal B-Cells and Epithelial Denudation.
PLoS One 2015 20;10(11):e0143316. Epub 2015 Nov 20.
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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Radical Prostatectomy versus External Beam Radiotherapy for cT1-4N0M0 Prostate Cancer: Comparison of Patient Outcomes Including Mortality.
PLoS One 2015 27;10(10):e0141123. Epub 2015 Oct 27.
Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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Association Between Plasma Levels of Macrophage Inhibitory Cytokine-1 Before Diagnosis of Colorectal Cancer and Mortality.
Gastroenterology 2015 Sep 27;149(3):614-22. Epub 2015 May 27.
Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address:
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Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer.
Carcinogenesis 2015 Sep 12;36(9):999-1007. Epub 2015 Jun 12.
Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA, Department of Epidemiology, Indiana University School of Public Health, Indianapolis, IN, USA,
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Metachronous tubulovillous and tubular adenomas of the anal canal.
Diagn Pathol 2015 Aug 7;10:139. Epub 2015 Aug 7.
Department of Surgical Oncology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
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TCEB1-mutated renal cell carcinoma: a distinct genomic and morphological subtype.
Mod Pathol 2015 Jun 13;28(6):845-53. Epub 2015 Feb 13.
Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans.
Genes Dev 2015 May 8;29(10):1074-86. Epub 2015 May 8.
Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts 02115, USA; Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA; Harvard Stem Cell Institute, Boston, Massachusetts 02115, USA; Howard Hughes Medical Institute, Boston, Massachusetts 02138, USA
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Recurrent cerebral aneurysm formation and rupture within a short period due to invasive aspergillosis of the nasal sinus; pathological analysis of the catastrophic clinical course.
Int J Clin Exp Pathol 2015 1;8(10):13510-22. Epub 2015 Oct 1.
Department of Neurosurgery, Faculty of Medicine, The University of Tokyo Tokyo, Japan.
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SMO expression in colorectal cancer: associations with clinical, pathological, and molecular features.
Ann Surg Oncol 2014 Dec 15;21(13):4164-73. Epub 2014 Jul 15.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Multiple primary malignant neoplasms of the glottis, renal pelvis, urinary bladder, oral floor, prostate, and esophagus in a Japanese male patient: a case report.
World J Surg Oncol 2014 Sep 22;12:294. Epub 2014 Sep 22.
Department of Urology, Tokyo Teishin Hospital, 2-14-23 Fujimi, Chiyoda-ku, Tokyo 102-8798, Japan.
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Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.
Ann Surg Oncol 2014 Aug 12;21(8):2650-8. Epub 2014 Apr 12.
Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan,
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A R0 resection case of initially unresectable metastatic pancreatic cancer downstaged by FOLFIRINOX therapy.
Pancreas 2014 Aug;43(6):972-4
Department of Gastroenterology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Department of Gastroenterology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Hepato-Biliary-Pancreatic Surgery Division Department of Surgery Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Department of Pathology and Diagnostic Pathology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Department of Gastroenterology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Hepato-Biliary-Pancreatic Surgery Division Department of Surgery Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Department of Pathology and Diagnostic Pathology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Hepato-Biliary-Pancreatic Surgery Division Department of Surgery Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan Department of Gastroenterology Graduate School of Medicine The University of Tokyo Bunkyo-ku, Tokyo, Japan.
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Expression of PRMT5 in lung adenocarcinoma and its significance in epithelial-mesenchymal transition.
Hum Pathol 2014 Jul 28;45(7):1397-405. Epub 2014 Feb 28.
Molecular Pathology Laboratory, Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
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Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome.
Science 2014 May;344(6186):917-20
Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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A prospective study of macrophage inhibitory cytokine-1 (MIC-1/GDF15) and risk of colorectal cancer.
J Natl Cancer Inst 2014 Apr 24;106(4):dju016. Epub 2014 Feb 24.
Affiliations of authors: Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (RSM, ATC); Gastrointestinal Research Group, Institute of Medical Sciences, Aberdeen University, Aberdeen, United Kingdom (NB); Department of Epidemiology (XG, SO, ELG) and Department of Nutrition (MS, KW, XG, ELG), Harvard School of Public Health, Boston, MA; Department of Pathology, University of Tokyo, Tokyo, Japan (TM); Channing Division of Network Medicine, Department of Medicine (CSF, ELG, ATC) and Department of Pathology (SO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA (CSF, SO).
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Concurrent activation of acetylation and tri-methylation of H3K27 in a subset of hepatocellular carcinoma with aggressive behavior.
PLoS One 2014 10;9(3):e91330. Epub 2014 Mar 10.
Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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Long-term results of radical prostatectomy with immediate adjuvant androgen deprivation therapy for pT3N0 prostate cancer.
BMC Urol 2014 Jan 29;14:13. Epub 2014 Jan 29.
Department of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
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Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations.
J Natl Cancer Inst 2013 Dec 7;105(24):1852-61. Epub 2013 Dec 7.
Affiliations of authors: Division of Cancer Epidemiology, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD (HN); Channing Division of Network Medicine, Department of Medicine (HN, DJH, ELG, CSF, ATC) and Department of Epidemiology (DJH, PK, ELG, SO), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Center for Molecular Oncologic Pathology (TM, YI, AK, MY, SO), Department of Medical Oncology (TM, MS, YI, AK, MY, CSF, SO, MLF), and Department of Biostatistics and Computational Biology (LW), Dana-Farber Cancer Institute, Boston, MA; Department of Epidemiology (DJH, ELG, SO) and Department of Nutrition, Harvard School of Public Health, Boston, MA (DJH, ELG); Broad Institute, Program in Medical and Population Genetics, Cambridge, MA (MLF); Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (ATC).
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Prognostic significance of MTOR pathway component expression in neuroendocrine tumors.
J Clin Oncol 2013 Sep 26;31(27):3418-25. Epub 2013 Aug 26.
Zhi Rong Qian, Monica Ter-Minassian, Jennifer A. Chan, Yu Imamura, Susanne M. Hooshmand, Aya Kuchiba, Teppei Morikawa, Lauren K. Brais, Anastassia Daskalova, Rachel Heafield, Charles S. Fuchs, Shuji Ogino, Matthew H. Kulke, Dana-Farber Cancer Institute and Harvard Medical School; Monica Ter-Minassian, Xihong Lin, David C. Christiani, Shuji Ogino, Harvard School of Public Health; David C. Christiani, Massachusetts General Hospital, Harvard Medical School; Charles S. Fuchs, Shuji Ogino, Brigham and Women's Hospital, Boston, MA.
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Long-term colorectal-cancer incidence and mortality after lower endoscopy.
N Engl J Med 2013 Sep;369(12):1095-105
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Integrated molecular analysis of clear-cell renal cell carcinoma.
Nat Genet 2013 Aug 24;45(8):860-7. Epub 2013 Jun 24.
Cancer Genomics Project, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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A prospective study of duration of smoking cessation and colorectal cancer risk by epigenetics-related tumor classification.
Am J Epidemiol 2013 Jul 20;178(1):84-100. Epub 2013 Jun 20.
Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Epidemiology, Harvard School of Public Health, 450 Brookline Avenue, Room JF-215C, Boston, MA 02215, USA.
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Physical activity, tumor PTGS2 expression, and survival in patients with colorectal cancer.
Cancer Epidemiol Biomarkers Prev 2013 Jun 29;22(6):1142-52. Epub 2013 Apr 29.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.
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Prospective analysis of body mass index, physical activity, and colorectal cancer risk associated with β-catenin (CTNNB1) status.
Cancer Res 2013 Mar 26;73(5):1600-10. Epub 2013 Feb 26.
Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave., Boston, MA 02215, USA.
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Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival.
Carcinogenesis 2013 Feb 26;34(2):292-8. Epub 2012 Oct 26.
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
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Prospective study of family history and colorectal cancer risk by tumor LINE-1 methylation level.
J Natl Cancer Inst 2013 Jan 21;105(2):130-40. Epub 2012 Nov 21.
Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Ave, Rm JF-215C, Boston, MA 02215, USA.
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Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.
Eur J Cancer 2012 Dec 26;48(18):3405-13. Epub 2012 Jul 26.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, United States.
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Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival.
N Engl J Med 2012 Oct;367(17):1596-606
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.
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Tumor TP53 expression status, body mass index and prognosis in colorectal cancer.
Int J Cancer 2012 Sep 19;131(5):1169-78. Epub 2011 Nov 19.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, and Department of Medicine Brigham and Women's Hospital, Boston, MA 02215, USA.
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Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.
Clin Cancer Res 2012 Sep 2;18(17):4753-63. Epub 2012 Jul 2.
Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Ave., Room JF-215C, Boston, MA 02215, USA.
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Predictors of lymph node count in colorectal cancer resections: data from US nationwide prospective cohort studies.
Arch Surg 2012 Aug;147(8):715-23
Department of Medical Oncology, Dana-Farber Cancer Institute and Havard Medical School, Boston, MA 02215, USA.
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No evidence for interference of h&e staining in DNA testing: usefulness of DNA extraction from H&E-stained archival tissue sections.
Am J Clin Pathol 2012 Jul;138(1):122-9
Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave, Room JF-208E, Boston, MA 02215, USA.
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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Nature 2012 Jul;487(7408):500-4
The Eli and Edythe L. Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.
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Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum.
Gut 2012 Jun 17;61(6):847-54. Epub 2012 Mar 17.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.
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Postmenopausal hormone therapy is associated with a reduced risk of colorectal cancer lacking CDKN1A expression.
Cancer Res 2012 Jun 17;72(12):3020-8. Epub 2012 Apr 17.
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA.
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Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer.
JAMA 2011 Apr;305(16):1685-94
Department of Medical Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215, USA.
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STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.
Clin Cancer Res 2011 Mar 10;17(6):1452-62. Epub 2011 Feb 10.
Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
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