Tenghui Chen

Tenghui Chen

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Tenghui Chen

Tenghui Chen

Publications by authors named "Tenghui Chen"

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19Publications

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Cancer driver mutation prediction through Bayesian integration of multi-omic data.

PLoS One 2018 8;13(5):e0196939. Epub 2018 May 8.

Department of Bioinformatics and Computational Biology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196939PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940219PMC
August 2018

REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.

Exp Dermatol 2017 11 30;26(11):1118-1124. Epub 2017 Aug 30.

Shanghai Key Laboratory of regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, China.

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http://doi.wiley.com/10.1111/exd.13394
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http://dx.doi.org/10.1111/exd.13394DOI Listing
November 2017

novoBreak: local assembly for breakpoint detection in cancer genomes.

Nat Methods 2017 01 28;14(1):65-67. Epub 2016 Nov 28.

Department of Bioinformatics and Computational Biology, The University of Texas Maryland Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nmeth.4084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199621PMC
January 2017

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.

Cell 2016 Oct 22;167(2):397-404.e9. Epub 2016 Sep 22.

Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088716PMC
http://dx.doi.org/10.1016/j.cell.2016.08.069DOI Listing
October 2016

Hotspot mutations delineating diverse mutational signatures and biological utilities across cancer types.

BMC Genomics 2016 06 23;17 Suppl 2:394. Epub 2016 Jun 23.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s12864-016-2727-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928158PMC
June 2016

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations.

Cancer Res 2015 Dec 1;75(24):5341-54. Epub 2015 Dec 1.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas. Dan L. Duncan Cancer Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681596PMC
December 2015

TransVar: a multilevel variant annotator for precision genomics.

Nat Methods 2015 Nov;12(11):1002-3

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nmeth.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772859PMC
November 2015

Differential proteomic profiling of primary and recurrent chordomas.

Oncol Rep 2015 May 26;33(5):2207-18. Epub 2015 Feb 26.

Department of Bone Tumor Surgery, Changzheng Hospital, Second Military Medical University, Shanghai 200003, P.R. China.

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http://dx.doi.org/10.3892/or.2015.3818DOI Listing
May 2015

REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.

Nat Commun 2015 Apr 24;6:6875. Epub 2015 Apr 24.

Department of Molecular Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms7875DOI Listing
April 2015

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis.

Cell Rep 2015 Mar 5;10(9):1599-1613. Epub 2015 Mar 5.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; The Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.02.014DOI Listing
March 2015

Bias from removing read duplication in ultra-deep sequencing experiments.

Bioinformatics 2014 04 2;30(8):1073-1080. Epub 2014 Jan 2.

Department of Bioinformatics and Computational Biology, Department of Systems Biology, Institute of Personalized Cancer Therapy and Department of Investigational Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston TX 77030, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982159PMC
April 2014

Mycoepoxydiene inhibits activation of BV2 microglia stimulated by lipopolysaccharide through suppressing NF-κB, ERK 1/2 and toll-like receptor pathways.

Int Immunopharmacol 2014 Mar 18;19(1):88-93. Epub 2014 Jan 18.

State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2014.01.004DOI Listing
March 2014

SRC-3 is required for CAR-regulated hepatocyte proliferation and drug metabolism.

J Hepatol 2012 Jan 7;56(1):210-7. Epub 2011 Aug 7.

State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, China.

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http://dx.doi.org/10.1016/j.jhep.2011.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232307PMC
January 2012

Steroid receptor coactivator 3 is required for clearing bacteria and repressing inflammatory response in Escherichia coli-induced septic peritonitis.

J Immunol 2010 Nov 29;185(9):5444-52. Epub 2010 Sep 29.

Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.

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http://dx.doi.org/10.4049/jimmunol.0903802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640995PMC
November 2010