Publications by authors named "Teepu Siddique"

82Publications

Disease-modifying effects of an structural variant in a predominantly ALS cohort.

Neurol Genet 2020 Aug 1;6(4):e470. Epub 2020 Jul 1.

Centre for Neuromuscular and Neurological Disorders (J.P., L.L.F., R.S.A., F.L.M., F.T., A.P., S.K., P.A.A.), University of Western Australia, Crawley; Perron Institute for Neurological and Translational Science (J.P., L.L.F., R.S.A., F.L.M., F.T., A.P., S.K., P.A.A.), Nedlands; Centre for Molecular Medicine and Innovative Therapeutics (L.L.F., A.P., S.K., P.A.A.), Murdoch University; School of Health Sciences (R.S.A.), and Institute for Health Research (R.S.A.), University of Notre Dame Australia, Fremantle; Institute for Immunology and Infectious Diseases (I.J.), Murdoch University, Australia; Department of Neurology (A.M.S., R.B., M.W.L., A.D.R.), Duke University School of Medicine, Durham, NC; Zinfandel Pharmaceuticals, Inc. (A.M.S., D.K.B., A.D.R.), Durham, NC; ALS Clinic (R.B.), Duke University, Durham, NC; Departments of Neurology, Pathology and Cell and Molecular Biology (N.S., T.S.), the Les Turner ALS Center, Northwestern University Feinberg School of Medicine; and the Northwestern University Interdepartmental Neuroscience Program (N.S., T.S.), Chicago, IL.

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http://dx.doi.org/10.1212/NXG.0000000000000470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357414PMC
August 2020

Association of a structural variant within the gene with amyotrophic lateral sclerosis.

Neurol Genet 2020 Apr 27;6(2):e406. Epub 2020 Feb 27.

University of Western Australia (J.P., R.S.A., L.L.F., F.T., L.J., F.L.M., P.A.A.), Centre for Neuromuscular and Neurological Disorders, Crawley; Perron Institute for Neurological and Translational Science (J.P., R.S.A., L.L.F., F.T., L.J., I.P., F.L.M., P.A.A.), Nedlands; University of Notre Dame Australia (R.S.A.), School of Health Sciences; University of Notre Dame Australia (R.S.A.), Institute for Health Research, Fremantle; Murdoch University (L.L.F., I.P., P.A.A.), Centre for Molecular Medicine and Innovative Therapeutics; Murdoch University, Institute for Immunology and Infectious Diseases (I.J.), Western Australia, Australia; Department of Neurology (R.B.), Duke University School of Medicine, Durham, NC; Zinfandel Pharmaceuticals (A.M.S.), Inc.; Duke University (R.B.), ALS Clinic, Durham, NC; and Departments of Neurology, Pathology and Cell and Molecular Biology (T.S., N.S.), Northwestern University Feinberg School of Medicine, the Les Turner ALS Center and the Northwestern University Interdepartmental Neuroscience Program, Chicago, IL.

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http://dx.doi.org/10.1212/NXG.0000000000000406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061286PMC
April 2020

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.

Neuron 2020 04 13;106(1):90-107.e13. Epub 2020 Feb 13.

The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2020.01.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272217PMC
April 2020

Incidence and Clinical Features of TRPV4-Linked Axonal Neuropathies in a USA Cohort of Charcot-Marie-Tooth Disease Type 2.

Neuromolecular Med 2020 03 29;22(1):68-72. Epub 2019 Aug 29.

Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.

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http://dx.doi.org/10.1007/s12017-019-08564-4DOI Listing
March 2020

Reply to 'TMEM230 variants in Parkinson's disease' and 'Doubts about TMEM230 as a gene for parkinsonism'.

Nat Genet 2019 03;51(3):369-371

Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/s41588-019-0355-5DOI Listing
March 2019

A novel ALS-associated variant in regulates motor axon morphogenesis.

Elife 2017 05 2;6. Epub 2017 May 2.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, United States.

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http://dx.doi.org/10.7554/eLife.25453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451210PMC
May 2017

Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus.

Elife 2017 05 2;6. Epub 2017 May 2.

Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, United States.

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http://dx.doi.org/10.7554/eLife.23759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449186PMC
May 2017

Early Impairment of Synaptic and Intrinsic Excitability in Mice Expressing ALS/Dementia-Linked Mutant UBQLN2.

Front Cell Neurosci 2016 20;10:216. Epub 2016 Sep 20.

Department of Physiology, Northwestern University Feinberg School of Medicine Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028382PMC
http://dx.doi.org/10.3389/fncel.2016.00216DOI Listing
September 2016

Macular sub-layer thinning and association with pulmonary function tests in Amyotrophic Lateral Sclerosis.

Sci Rep 2016 07 7;6:29187. Epub 2016 Jul 7.

Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1038/srep29187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935870PMC
July 2016

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.

Neuron 2016 07 16;91(1):41-55. Epub 2016 Jun 16.

Department of Pathology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA; Pathology Service 113B, VA Medical Center, San Francisco, CA 94121, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2016.05.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938715PMC
July 2016

Compound heterozygote mutations in SPG7 in a family with adult-onset primary lateral sclerosis.

Neurol Genet 2016 Apr 3;2(2):e60. Epub 2016 Mar 3.

Department of Histology and Embryology (Y.Y., L.Z.), Hebei Medical University, China; Division of Neuromuscular Medicine (Y.Y., K.A., E.R., J.H.N., H.-X.D., N.S., T.S.), Davee Department of Neurology and Clinical Neurosciences and Department of Pharmacology (T.J.L.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (D.L.) and Department of Pediatrics (P.M.A.S.), the Perelman School of Medicine, University of Pennsylvania, Philadelphia; and Department of Neurology (K.A.S.) and The Center for Applied Genomics (P.M.A.S.), The Children's Hospital of Philadelphia, PA.

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http://dx.doi.org/10.1212/NXG.0000000000000060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830188PMC
April 2016

Ophthalmic Manifestations of Amyotrophic Lateral Sclerosis (An American Ophthalmological Society Thesis).

Trans Am Ophthalmol Soc 2015 ;113:T12

Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731009PMC
July 2016

ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation.

PLoS One 2015 8;10(5):e0125638. Epub 2015 May 8.

Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 60611, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125638PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425507PMC
February 2016

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.

Nat Neurosci 2014 Dec 26;17(12):1710-9. Epub 2014 Oct 26.

1] Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nn.3853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703324PMC
December 2014

Reproductive decision-making among individuals at risk for familial amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2015 Mar 10;16(1-2):114-9. Epub 2014 Sep 10.

VHA Central Office: Genomic Medicine Service, Department of Veterans Affairs , Salt Lake City, Utah , USA.

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http://dx.doi.org/10.3109/21678421.2014.951945DOI Listing
March 2015

Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.

Neurogenetics 2015 Jan 6;16(1):1-9. Epub 2014 Sep 6.

Division of Neuromuscular Medicine, The Ken and Ruth Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA,

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http://link.springer.com/10.1007/s10048-014-0421-1
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http://dx.doi.org/10.1007/s10048-014-0421-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796476PMC
January 2015

Sporadic and hereditary amyotrophic lateral sclerosis (ALS).

Biochim Biophys Acta 2015 Apr 1;1852(4):679-84. Epub 2014 Sep 1.

Division of Neuromuscular Medicine, The Ken and Ruth Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine Northwestern University, Chicago, IL 60611, USA; Department of Cell and Molecular Biology, Feinberg School of Medicine Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.bbadis.2014.08.010DOI Listing
April 2015

Protein recycling pathways in neurodegenerative diseases.

Alzheimers Res Ther 2014 6;6(2):13. Epub 2014 Mar 6.

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Tarry Building, Room 13-715, 303 East Chicago Avenue, Chicago, IL 60611, USA ; Interdepartmental Neuroscience Program, Northwestern University, Chicago, IL 60611, USA ; Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://alzres.biomedcentral.com/articles/10.1186/alzrt243
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http://dx.doi.org/10.1186/alzrt243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055009PMC
July 2014

Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expression.

Bioorg Med Chem Lett 2014 Mar 8;24(6):1532-7. Epub 2014 Feb 8.

Department of Neurology, Northwestern University, Chicago, IL 60611, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.01.078DOI Listing
March 2014

Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.

Acta Neuropathol 2014 Feb 18;127(2):243-56. Epub 2013 Oct 18.

Department of Neurochemistry, Inge Grundke-Iqbal Research Floor, New York State Institute for Basic Research, In Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY, 10314-6399, USA.

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http://dx.doi.org/10.1007/s00401-013-1175-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947003PMC
February 2014

Genetic and epigenetic studies of amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2013 May;14 Suppl 1:44-52

King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK.

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http://dx.doi.org/10.3109/21678421.2013.778571DOI Listing
May 2013

Gastrostomy tube placement by endoscopy versus radiologic methods in patients with ALS: a retrospective study of complications and outcome.

Amyotroph Lateral Scler Frontotemporal Degener 2013 May 4;14(4):308-14. Epub 2013 Jan 4.

Department of Neurology, Division of Neuromuscular Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3109/21678421.2012.751613DOI Listing
May 2013

Prevalence and characteristics of pain in early and late stages of ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2013 Sep 4;14(5-6):369-72. Epub 2013 Jan 4.

The Ken and Ruth Davee Department of Neurology and Clinical Neurological Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3109/21678421.2012.751614DOI Listing
September 2013

UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia.

Muscle Nerve 2012 Feb;45(2):157-62

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University, Feinberg School of Medicine, Tarry Building, Room 13-715, 303 East Chicago Avenue, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1002/mus.23278DOI Listing
February 2012

What is repeated in ALS and FTLD.

Lancet Neurol 2012 Jan 7;11(1):25-7. Epub 2011 Dec 7.

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/S1474-4422(11)70275-7DOI Listing
January 2012

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.

Arch Neurol 2011 Nov;68(11):1440-6

Division of Neuromuscular Medicine, Ken and Ruth Davee Department of Neurology and Clinical Neurological Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archneurol.2011.250DOI Listing
November 2011

Detection of protein aggregation in neurodegenerative diseases.

Methods Mol Biol 2011 ;793:259-72

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1007/978-1-61779-328-8_17DOI Listing
December 2011

Making connections: pathology and genetics link amyotrophic lateral sclerosis with frontotemporal lobe dementia.

J Mol Neurosci 2011 Nov 7;45(3):663-75. Epub 2011 Sep 7.

Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, Tarry Building, Room 13-715, 303 East Chicago Ave., Chicago, IL 60611, USA.

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http://dx.doi.org/10.1007/s12031-011-9637-9DOI Listing
November 2011

Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations.

Arch Neurol 2011 Aug;68(8):1057-61

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1001/archneurol.2011.178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357952PMC
August 2011

Confirmation of the severe phenotypic effect of serine at codon 41 of the superoxide dismutase 1 gene.

Muscle Nerve 2011 Oct 13;44(4):499-502. Epub 2011 Jul 13.

Department of Neurology, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1002/mus.22117DOI Listing
October 2011

Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies.

J Biol Chem 2011 May 21;286(19):17281-91. Epub 2011 Mar 21.

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M111.237685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089570PMC
May 2011

Recent advances in the genetics of hereditary axonal sensory-motor neuropathies type 2.

Curr Neurol Neurosci Rep 2011 Jun;11(3):262-73

Division of Neuromuscular Medicine, Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Tarry Building, Room 13-715, 303 East Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1007/s11910-011-0185-zDOI Listing
June 2011

An unusual case of familial ALS and cerebellar ataxia.

Amyotroph Lateral Scler 2010 Dec 14;11(6):568-70. Epub 2010 Jun 14.

Department of Neurology, University of Texas Medical School at Houston, 6431 Fannin Street, Houston, TX 77030, USA.

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http://dx.doi.org/10.3109/17482961003636874DOI Listing
December 2010

Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.

Nat Genet 2010 Feb 27;42(2):165-9. Epub 2009 Dec 27.

Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786192PMC
February 2010

Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis.

J Neurosci 2009 Dec;29(48):15031-8

Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0574-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000669PMC
December 2009

Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis.

J Biol Chem 2010 Jan 4;285(1):705-12. Epub 2009 Nov 4.

Department of Molecular Biophysics and Physiology, Rush University Medical School, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1074/jbc.M109.041319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804218PMC
January 2010

Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis.

J Lipid Res 2010 Apr 7;51(4):819-23. Epub 2009 Oct 7.

Hertie Institute for Clinical Brain Research and Center of Neurology, University of Tubingen, Tubingen, Germany.

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http://dx.doi.org/10.1194/jlr.M002543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842155PMC
April 2010

Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.

Hum Mol Genet 2009 May 19;18(9):1642-51. Epub 2009 Feb 19.

Department of Neurology, The University of Chicago Pritzker School of Medicine, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/ddp085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667291PMC
May 2009

Oculomotor involvement in myotonic dystrophy type 2.

Muscle Nerve 2008 Oct;38(4):1326-9

Davee Department of Neurology and Clinical Neurosciences, Feinberg School of Medicine, Northwestern University, 710 North Lake Shore Drive, Abbott Hall 1426, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1002/mus.21113DOI Listing
October 2008

Genetics of amyotrophic lateral sclerosis.

Phys Med Rehabil Clin N Am 2008 Aug;19(3):429-39, vii

Neuromuscular Disorders Program, Northwestern University, Feinberg School of Medicine, Tarry Building, Room13-715, 303 East Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.pmr.2008.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553626PMC
August 2008

Gender difference in levels of Cu/Zn superoxide dismutase (SOD1) in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2008 Jun;9(3):184-7

Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1080/17482960801984358DOI Listing
June 2008

Molecular dissection of ALS-associated toxicity of SOD1 in transgenic mice using an exon-fusion approach.

Hum Mol Genet 2008 Aug 18;17(15):2310-9. Epub 2008 Apr 18.

Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/hmg/ddn131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465800PMC
August 2008

What is missing in ALS.

Authors:
Teepu Siddique

Lancet Neurol 2008 Apr 3;7(4):289-90. Epub 2008 Mar 3.

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http://dx.doi.org/10.1016/S1474-4422(08)70049-8DOI Listing
April 2008

Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology.

Neurobiol Dis 2008 Mar 23;29(3):400-8. Epub 2007 Oct 23.

Department of Neurology/MC2030, The University of Chicago Pritzker School of Medicine, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09699961070023
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http://dx.doi.org/10.1016/j.nbd.2007.10.004DOI Listing
March 2008

Distal axonopathy in an alsin-deficient mouse model.

Hum Mol Genet 2007 Dec 12;16(23):2911-20. Epub 2007 Sep 12.

Department of Neurology and Clinical Neurosciences, Northwestern University Institute for Neuroscience, Chicago, IL 60611, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddm251DOI Listing
December 2007

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.

Amyotroph Lateral Scler 2007 Oct;8(5):305-9

Davee Department of Neurology and Clinical Neurosciences, Northwestern University Institute of Neuroscience, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1080/17482960701500650DOI Listing
October 2007

Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions.

Acta Neuropathol 2007 Jul 14;114(1):81-94. Epub 2007 Jun 14.

Cognitive Neurology and Alzheimer Disease Center, Northwestern University, Feinberg School of Medicine, 320 East Superior St, Chicago, IL, 60611, USA.

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http://link.springer.com/content/pdf/10.1007/s00401-007-0240
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http://link.springer.com/10.1007/s00401-007-0240-7
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http://dx.doi.org/10.1007/s00401-007-0240-7DOI Listing
July 2007

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.

Proc Natl Acad Sci U S A 2006 May 24;103(18):7142-7. Epub 2006 Apr 24.

Davee Department of Neurology and Clinical Neurosciences, Northwestern University Feinberg School of Medicine, Tarry Building, Room 13-715, 303 East Chicago Avenue, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1073/pnas.0602046103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447523PMC
May 2006

Informatics-assisted protein profiling in a transgenic mouse model of amyotrophic lateral sclerosis.

Mol Cell Proteomics 2006 Jul 29;5(7):1233-44. Epub 2006 Mar 29.

Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/mcp.M500431-MCP200DOI Listing
July 2006

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.

Ann Neurol 2005 Dec;58(6):858-64

Department of Neurology, Pritzker School of Medicine and Center for Comprehensive Care and Research on Memory Disorders, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1002/ana.20646DOI Listing
December 2005

Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis.

Neurogenetics 2004 Dec 2;5(4):209-13. Epub 2004 Oct 2.

Center for Human Genetics, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://link.springer.com/10.1007/s10048-004-0193-0
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http://dx.doi.org/10.1007/s10048-004-0193-0DOI Listing
December 2004

Genome-wide analysis of the parkinsonism-dementia complex of Guam.

Arch Neurol 2004 Dec;61(12):1889-97

Department of Molecular Pathogenesis and Sara Koe PSP Research Centre, Queen Square Brain Bank for Neurological Disorders, Insatitute of Neurology, University College London, London, England, UK.

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http://dx.doi.org/10.1001/archneur.61.12.1889DOI Listing
December 2004

Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis.

J Neuropathol Exp Neurol 2004 Aug;63(8):801-11

Northwestern Cognitive Neurology and Alzheimer Disease Center, and Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1093/jnen/63.8.801DOI Listing
August 2004

Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.

J Neurophysiol 2004 Jan 1;91(1):571-5. Epub 2003 Oct 1.

Department of Physiology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1152/jn.00665.2003DOI Listing
January 2004

A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy.

Amyotroph Lateral Scler Other Motor Neuron Disord 2003 Sep;4(3):162-6

Department of Neurology, The University of Chicago, 5841 S. Maryland Ave/MC2030, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1080/aml.4.3.162.166DOI Listing
September 2003

A4T mutation in the SOD1 gene causing familial amyotrophic lateral sclerosis.

Neuroepidemiology 2003 Jul-Aug;22(4):235-8

Department of Neurology, Burhan Nalbantoglu Hospital, Lefkosa (Nicosia), Cyprus, UK.

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http://dx.doi.org/10.1159/000070564DOI Listing
July 2003

Cholinergic denervation in a pure multi-infarct state: observations on CADASIL.

Neurology 2003 Apr;60(7):1183-5

Cognitive Neurology and Alzheimer's Disease Center and the Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1212/01.wnl.0000055927.22611.ebDOI Listing
April 2003

Genetic aspects of amyotrophic lateral sclerosis.

Adv Neurol 2002 ;88:21-32

Departments of Neurology and Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

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September 2002