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Severity: Notice

Message: Undefined offset: 30999631

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30951861

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 30862565

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29339412

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 29267987

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28362432

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28336725

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26894679

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26876500

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26342231

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26217671

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 26001071

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25937245

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 28706685

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 25543083

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24710632

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24661138

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24583282

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24416158

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24305735

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 24007918

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23780840

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23776060

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23482663

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 23354592

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22975370

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22966490

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22916255

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22556265

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 22361111

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21472523

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21368573

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21350334

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21245151

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21191186

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 21056992

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20888340

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20851891

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20847049

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20663147

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20656489

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20436290

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20303977

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 20157532

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19897041

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19878314

Filename: controllers/Author.php

Line Number: 1493

Backtrace:

File: /var/www/html/application/controllers/Author.php
Line: 1493
Function: _error_handler

File: /var/www/html/application/controllers/Author.php
Line: 1271
Function: pubMedSearchtoAuthorResults_array

File: /var/www/html/application/controllers/Author.php
Line: 333
Function: pubMedAuthorSearch_array

File: /var/www/html/index.php
Line: 322
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Undefined offset: 19878313

Filename: controllers/Author.php

Line Number: 1493

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Publications Authored by Ted R Hupp | PubFacts
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The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis.

Cell Signal 2019 Aug 2;60:39-56. Epub 2019 Apr 2.

University of Edinburgh, Institute of Genetics and Molecular Medicine, Edinburgh EH4 2XR, United Kingdom; Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic; University of Gdansk, International Centre for Cancer Vaccine Science, Department of Chemistry, Gdansk, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08986568193007
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http://dx.doi.org/10.1016/j.cellsig.2019.03.024DOI Listing
August 2019

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin.

J Proteomics 2019 May 9;199:89-101. Epub 2019 Mar 9.

University of Edinburgh, Institute of Quantitative Biology, Biochemistry and Biotechnology, Edinburgh, Scotland EH9 3BF, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S18743919193006
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http://dx.doi.org/10.1016/j.jprot.2019.02.012DOI Listing
May 2019

Regulation of the Expression of DAPK1 by SUMO Pathway.

Biomolecules 2019 04 17;9(4). Epub 2019 Apr 17.

Provincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou 350117, China.

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https://www.mdpi.com/2218-273X/9/4/151
Publisher Site
http://dx.doi.org/10.3390/biom9040151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523460PMC
April 2019

The Sequence-specific Peptide-binding Activity of the Protein Sulfide Isomerase AGR2 Directs Its Stable Binding to the Oncogenic Receptor EpCAM.

Mol Cell Proteomics 2018 04 16;17(4):737-763. Epub 2018 Jan 16.

From the ‡University of Edinburgh, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, United Kingdom, EH4 2XR;

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http://dx.doi.org/10.1074/mcp.RA118.000573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880107PMC
April 2018

Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity.

Chemistry 2018 Feb 19;24(9):2094-2097. Epub 2018 Jan 19.

EaStChem School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.

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http://dx.doi.org/10.1002/chem.201705983DOI Listing
February 2018

Quantitative Shotgun Proteomics Unveils Candidate Novel Esophageal Adenocarcinoma (EAC)-specific Proteins.

Mol Cell Proteomics 2017 06 23;16(6):1138-1150. Epub 2017 Mar 23.

From the ‡Edinburgh Cancer Research Centre at the Institute of Genetics and Molecular Medicine, Edinburgh University.

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http://dx.doi.org/10.1074/mcp.M116.065078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461543PMC
June 2017

Regulation of transcriptional activators by DNA-binding domain ubiquitination.

Cell Death Differ 2017 05 31;24(5):903-916. Epub 2017 Mar 31.

Cell Signalling Unit, ECRC, IGMM, University of Edinburgh, Edinburgh EH4 2XR, UK.

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http://dx.doi.org/10.1038/cdd.2017.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423116PMC
May 2017

Mass spectrometry analysis of the oxidation states of the pro-oncogenic protein anterior gradient-2 reveals covalent dimerization via an intermolecular disulphide bond.

Biochim Biophys Acta 2016 May 10;1864(5):551-61. Epub 2016 Feb 10.

University of Edinburgh, Institute of Genetics and Molecular Medicine, Division of Cancer Biology, Edinburgh, Scotland EH4 2XR, United Kingdom; Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, 656 53 Brno, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.bbapap.2016.02.011DOI Listing
May 2016

MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4.

PLoS One 2015 22;10(5):e0127713. Epub 2015 May 22.

Division of Cancer Research, University of Dundee, Clinical Research Centre and Jacqui Wood Cancer Centre, Ninewells Hospital, James Arrott Drive, Dundee, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127713PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441487PMC
April 2016

Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets.

Bioinformatics 2016 Jan 5;32(1):9-16. Epub 2015 Sep 5.

RECAMO, Masaryk Memorial Cancer Institute, Zluty kopec 7, 65653, Brno, Czech Republic.

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http://dx.doi.org/10.1093/bioinformatics/btv522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681989PMC
January 2016

Mechanisms of anterior gradient-2 regulation and function in cancer.

Semin Cancer Biol 2015 Aug 30;33:16-24. Epub 2015 Apr 30.

Masaryk Memorial Cancer Institute, RECAMO, Zluty kopec 7, 65653 Brno, Czech Republic; Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research Centre Cell Signalling Unit, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2015.04.005DOI Listing
August 2015

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors.

Front Mol Biosci 2015 10;2:39. Epub 2015 Jul 10.

The Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, School of Chemistry, University of Manchester Manchester, UK.

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http://dx.doi.org/10.3389/fmolb.2015.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498441PMC
July 2015

Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis.

J Mol Biol 2015 Apr 24;427(8):1728-47. Epub 2014 Dec 24.

Institute of Genetics and Molecular Medicine, Cell Signalling Unit, Edinburgh Cancer Research Centre, University of Edinburgh, Edinburgh EH8 9YL, United Kingdom. Electronic address:

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April 2015

Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.

PLoS One 2014 8;9(1):e83144. Epub 2014 Jan 8.

Royal (Dick) School of Veterinary Studies and Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, United Kingdom.

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September 2014

A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2.

Cell Signal 2014 Jun 28;26(6):1243-57. Epub 2014 Feb 28.

Edinburgh Cancer Research Centre, Cell Signalling Unit, University of Edinburgh, EH4 2XR, United Kingdom. Electronic address:

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June 2014

Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2.

Mol Biosyst 2014 Jun 7;10(6):1409-25. Epub 2014 Apr 7.

Cell Signalling Unit, p53 Signal Transduction Laboratories, Edinburgh Cancer Research Centre, Western General Hospital, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UKEH4 2XR.

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http://dx.doi.org/10.1039/c4mb00113cDOI Listing
June 2014

Quantitative proteomic profiling of pleomorphic human sarcoma identifies CLIC1 as a dominant pro-oncogenic receptor expressed in diverse sarcoma types.

J Proteome Res 2014 May 9;13(5):2543-59. Epub 2014 Apr 9.

University of Edinburgh , Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research Centre, South Crewe Road, Edinburgh EH4 2XR, United Kingdom.

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May 2014

Evaluating DAPK as a therapeutic target.

Apoptosis 2014 Feb;19(2):371-86

Fujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University, Fuzhou, 350108, Fujian, People's Republic of China.

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February 2014

A Casein kinase 1/Checkpoint kinase 1 pyrazolo-pyridine protein kinase inhibitor as novel activator of the p53 pathway.

Bioorg Med Chem Lett 2013 Oct 16;23(20):5578-85. Epub 2013 Aug 16.

p53 Signal Transduction Group, University of Edinburgh Cancer Research Centre in the Institute of Genetics and Molecular Medicine, Crewe Road South, Edinburgh EH4 2XR, United Kingdom.

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October 2013

Development of a fluorescent monoclonal antibody-based assay to measure the allosteric effects of synthetic peptides on self-oligomerization of AGR2 protein.

Protein Sci 2013 Sep 25;22(9):1266-78. Epub 2013 Jul 25.

Institute of Genetics and Molecular Medicine, Cell Signaling Unit, University of Edinburgh, United Kingdom.

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September 2013

Identification of an AKT-dependent signalling pathway that mediates tamoxifen-dependent induction of the pro-metastatic protein anterior gradient-2.

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Masaryk Memorial Cancer Institute, Regional Centre for Applied Molecular Oncology, Zluty kopec 7, 656 53 Brno, Czech Republic.

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June 2013

The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape.

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Université Bordeaux, Physiopathologie du Cancer du Foie, U1053, F-33000 Bordeaux, France.

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March 2013

Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth.

PLoS One 2012 20;7(8):e43391. Epub 2012 Aug 20.

p53 Signal Transduction Group, Edinburgh Cancer Research Centre in the Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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January 2013

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Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

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September 2012

Nanosensing protein allostery using a bivalent mouse double minute two (MDM2) assay.

Proc Natl Acad Sci U S A 2012 May 3;109(21):8073-8. Epub 2012 May 3.

Centre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL, United Kingdom.

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May 2012

Anterior Gradient-3: a novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models.

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p53 Signal Transduction Group, Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XR, Scotland, UK.

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April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404883PMC
http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry.

J Am Soc Mass Spectrom 2011 May 24;22(5):888-97. Epub 2011 Feb 24.

SIRCAMS, School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, UK.

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http://dx.doi.org/10.1007/s13361-011-0088-xDOI Listing
May 2011

A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1.

J Biol Chem 2011 Apr 18;286(16):14291-303. Epub 2011 Jan 18.

CRUK Interferon and Cell Signalling Group, Cell Signalling Unit, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M110.204602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077630PMC
April 2011

How phosphorylation controls p53.

Cell Cycle 2011 Mar 15;10(6):916-21. Epub 2011 Mar 15.

CRUK p53 Signal Transduction Group, Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Scotland, UK.

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http://dx.doi.org/10.4161/cc.10.6.15076DOI Listing
March 2011

p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.

Cell Cycle 2011 Mar 15;10(6):932-50. Epub 2011 Mar 15.

CRUK Cell Signalling Unit, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.4161/cc.10.6.15012DOI Listing
March 2011

A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin.

J Mol Biol 2010 Dec 1;404(3):418-38. Epub 2010 Oct 1.

Cancer Research UK p53 Signal Transduction Laboratories, Cell Signalling Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EX4 2XR, Scotland, UK.

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http://dx.doi.org/10.1016/j.jmb.2010.09.035DOI Listing
December 2010

Mage-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin.

Cancer Res 2010 Dec 5;70(24):10362-70. Epub 2010 Nov 5.

Biomedical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1341DOI Listing
December 2010

A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53.

J Biol Chem 2010 Nov 16;285(48):37773-86. Epub 2010 Sep 16.

CRUK p53 Signal Transduction Group, Cell Signaling Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, Scotland, United Kingdom.

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http://www.jbc.org/content/early/2010/09/17/jbc.M110.143099.
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http://www.jbc.org/cgi/doi/10.1074/jbc.M110.143107
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http://dx.doi.org/10.1074/jbc.M110.143107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988382PMC
November 2010

A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.

J Biol Chem 2010 Nov 17;285(48):37762-72. Epub 2010 Sep 17.

Institute of Genetics and Molecular Medicine, CRUK Cancer Research Centre, University of Edinburgh, Edinburgh EH4 2XR, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M110.143099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988381PMC
November 2010

Drug discovery and mutant p53.

Trends Cell Biol 2010 Sep 24;20(9):542-55. Epub 2010 Jul 24.

University of Edinburgh, Institute of Genetics and Molecular Medicine, Cell Signalling Unit, Cancer Research UK p53 Signal Transduction Group, Edinburgh EH4 2XR, UK.

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http://dx.doi.org/10.1016/j.tcb.2010.06.005DOI Listing
September 2010

DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation.

Mol Cancer 2010 Jul 21;9:195. Epub 2010 Jul 21.

Cell Signalling Unit, Cancer Research Center, Western General Hospital, University of Edinburgh, Edinburgh EH4 2XR, UK.

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http://dx.doi.org/10.1186/1476-4598-9-195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098010PMC
July 2010

The effects of phosphomimetic lid mutation on the thermostability of the N-terminal domain of MDM2.

J Mol Biol 2010 May 19;398(3):414-28. Epub 2010 Mar 19.

Institute of Genetics and Molecular Medicine, CRUK Cancer Research Center, University of Edinburgh, Edinburgh EH4 2XR, UK.

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http://dx.doi.org/10.1016/j.jmb.2010.03.023DOI Listing
May 2010

The molecular dynamics of MDM2.

Cell Cycle 2010 May 15;9(10):1878-81. Epub 2010 May 15.

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http://dx.doi.org/10.4161/cc.9.10.11597DOI Listing
May 2010

The regulation of MDM2 by multisite phosphorylation--opportunities for molecular-based intervention to target tumours?

Semin Cancer Biol 2010 Feb 6;20(1):19-28. Epub 2009 Nov 6.

Biomedical Research Institute, The University of Dundee, Ninewells Hospital, Biomedical Research Institute, Dundee, United Kingdom.

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http://dx.doi.org/10.1016/j.semcancer.2009.10.005DOI Listing
February 2010

Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death.

FEBS J 2010 Jan 26;277(1):48-57. Epub 2009 Oct 26.

CRUK p53 Signal Transduction Laboratories, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07411.xDOI Listing
January 2010

Death-associated protein kinase (DAPK) and signal transduction.

Authors:
Ted R Hupp

FEBS J 2010 Jan 30;277(1):47. Epub 2009 Oct 30.

CRUK p53 Signal Transduction Laboratories, Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1742-4658.2009.07410.xDOI Listing
January 2010

CK1alpha plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability.

J Biol Chem 2009 Nov 15;284(47):32384-94. Epub 2009 Sep 15.

Cancer Research UK p53 Signal Transduction Group, University of Edinburgh, Institute of Genetics and Molecular Medicine, Division of Cancer Biology, Crewe Road South, Edinburgh EH4 2XR, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M109.052647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781653PMC
November 2009

The alternative splice variant of DAPK-1, s-DAPK-1, induces proteasome-independent DAPK-1 destabilization.

Mol Cell Biochem 2009 Aug 8;328(1-2):101-7. Epub 2009 Mar 8.

Institute of Genetics and Molecular Medicine, University of Edinburgh, UK.

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http://dx.doi.org/10.1007/s11010-009-0079-4DOI Listing
August 2009

Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif.

J Chem Biol 2009 Aug 16;2(3):113-29. Epub 2009 May 16.

CRUK p53 Signal Transduction Group, University of Edinburgh, Edinburgh, Scotland, UK, EH4 2XR.

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http://dx.doi.org/10.1007/s12154-009-0019-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725272PMC
August 2009

The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway.

Aging (Albany NY) 2009 May 7;1(5):490-502. Epub 2009 May 7.

University of Edinburgh, Institute of Genetics and Molecular Medicine, CRUK p53 Signal Transduction Laboratories, Edinburgh, EH4 2XR, Scotland, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806026PMC
http://dx.doi.org/10.18632/aging.100047DOI Listing
May 2009

A function for the RING finger domain in the allosteric control of MDM2 conformation and activity.

J Biol Chem 2009 Apr 2;284(17):11517-30. Epub 2009 Feb 2.

Cancer Research UK (CRUK) Interferon and Cell Signalling Group, University of Edinburgh, Crewe Road South, Edinburgh EH4 2SR, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M809294200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670157PMC
April 2009

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1.

FEBS J 2008 Oct 27;275(19):4875-86. Epub 2008 Aug 27.

Cell Signaling Unit, University of Edinburgh, UK.

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http://dx.doi.org/10.1111/j.1742-4658.2008.06627.xDOI Listing
October 2008

Protein kinases coordinately regulate the p53: Delta Np63 alpha axis after DNA damage.

Cell Cycle 2008 Sep 15;7(18):2779-80. Epub 2008 Sep 15.

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http://dx.doi.org/10.4161/cc.7.18.6891DOI Listing
September 2008

Novel insights into DAPK autophagic signalling using peptide aptamer combinatorial protein-interaction screens.

Autophagy 2008 May 20;4(4):531-3. Epub 2008 Mar 20.

University of Edinburgh, Institute of Genetics and Molecular Medicine, Division of Cancer Biology, CRUK p53 Signal Transduction Group, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.4161/auto.5940DOI Listing
May 2008

DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.

J Biol Chem 2008 Apr 14;283(15):9999-10014. Epub 2008 Jan 14.

University of Edinburgh Cancer Centre, Cell Signalling Unit, South Crewe Road, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M706040200DOI Listing
April 2008

Microarray-formatted clinical biomarker assay development using peptide aptamers to anterior gradient-2.

Biochemistry 2007 Dec 10;46(48):13742-51. Epub 2007 Nov 10.

CRUK p53 Signal Transduction Group, Cell Signalling Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1021/bi7008739DOI Listing
December 2007

Multienzyme assembly of a p53 transcription complex.

Nat Struct Mol Biol 2007 Oct;14(10):885-7

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http://www.nature.com/articles/nsmb1007-885
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October 2007

p63: the phantom of the tumor suppressor.

Cell Cycle 2007 May 19;6(9):1062-71. Epub 2007 May 19.

Chromosomes and Gene Expression Laboratory, MRC Human Genetics Unit, Edinburgh, Scotland, UK.

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http://dx.doi.org/10.4161/cc.6.9.4162DOI Listing
May 2007

Chemical genetics approach to identify peptide ligands that selectively stimulate DAPK-1 kinase activity.

Biochemistry 2007 Mar 13;46(10):2655-73. Epub 2007 Feb 13.

Cancer Research UK p53 Signal Transduction Group, University of Edinburgh Cancer Research Centre, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, UK.

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http://pubs.acs.org/doi/abs/10.1021/bi061562j
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March 2007

CK2-site phosphorylation of p53 is induced in DeltaNp63 expressing basal stem cells in UVB irradiated human skin.

Cell Cycle 2006 Nov 12;5(21):2489-94. Epub 2006 Sep 12.

The University of Edinburgh, CRUK p53 Signal Transduction Group, Edinburgh, UK.

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http://dx.doi.org/10.4161/cc.5.21.3393DOI Listing
November 2006

The role of modelling in identifying drug targets for diseases of the cell cycle.

J R Soc Interface 2006 Oct;3(10):617-27

SIMBIOS, University of Abertay Dundee, Kydd Building, Bell Street, Dundee DD1 1HG, UK.

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http://dx.doi.org/10.1098/rsif.2006.0146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664649PMC
October 2006

Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo.

Biochem J 2006 Jul;397(2):355-67

Cancer Research UK Cell Signalling Unit, p53 Signal Transduction Group, University of Edinburgh, South Crewe Road, Edinburgh EH4 2XR, Scotland, UK.

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http://dx.doi.org/10.1042/BJ20051521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513284PMC
July 2006

Dual-site regulation of MDM2 E3-ubiquitin ligase activity.

Mol Cell 2006 Jul;23(2):251-63

CRUK Interferon and Cell Signalling Group, University of Edinburgh Cancer Research Centre, Crewe Road South, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1016/j.molcel.2006.05.029DOI Listing
July 2006

On the mechanism of sequence-specific DNA-dependent acetylation of p53: the acetylation motif is exposed upon DNA binding.

J Mol Biol 2006 Mar 27;357(2):442-56. Epub 2005 Dec 27.

CRUK Cell Signaling Unit, University of Edinburgh, South Crewe Road, Edinburgh EH4 2XR, UK.

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http://dx.doi.org/10.1016/j.jmb.2005.12.026DOI Listing
March 2006

The N-terminal interferon-binding domain (IBiD) homology domain of p300 binds to peptides with homology to the p53 transactivation domain.

J Biol Chem 2004 Nov 26;279(47):49395-405. Epub 2004 Aug 26.

University of Edinburgh, Division of Oncology, CRUK Cell Signaling Unit, South Crewe Road, Edinburgh EH4 2XU, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M405974200DOI Listing
November 2004

The regulation of CHK2 in human cancer.

Oncogene 2004 Nov;23(52):8411-8

University of Edinburgh, CRUK Cancer Research Center, p53 Signal Transduction Group, South Crewe Road, Edinburgh, UK.

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http://dx.doi.org/10.1038/sj.onc.1208035DOI Listing
November 2004

Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53.

Mol Cell Biol 2004 Nov;24(22):10083-98

CRUK Interferon and Cell Signalling Group, Cell Signalling Unit, Cancer Research Centre, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1128/MCB.24.22.10083-10098.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525491PMC
November 2004

The Barrett's antigen anterior gradient-2 silences the p53 transcriptional response to DNA damage.

Mol Cell Proteomics 2004 Jun 15;3(6):534-47. Epub 2004 Feb 15.

Cancer Research UK Laboratories, Department of Molecular and Cellular Pathology, University of Dundee, Dundee DD1 9SY, United Kingdom.

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http://dx.doi.org/10.1074/mcp.M300089-MCP200DOI Listing
June 2004

Signaling to p53: the use of phospho-specific antibodies to probe for in vivo kinase activation.

Methods Mol Biol 2003 ;234:171-202

Department of Cellular and Molecular Pathology, Ninewells Hospital and Medical School, Dundee University, Tayside, Scotland, UK.

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http://dx.doi.org/10.1385/1-59259-408-5:171DOI Listing
April 2004

Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein.

J Mol Biol 2004 Mar;337(1):129-45

Cancer Research UK Laboratories, Department of Molecular and Cellular Pathology, The University of Dundee, Dundee DD1 9SY, Scotland, UK.

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http://dx.doi.org/10.1016/j.jmb.2004.01.017DOI Listing
March 2004

The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53.

Mol Cell Biol 2003 Dec;23(23):8846-61

Cancer Research UK Laboratories, P53 Signal Transduction Group, Department of Molecular and Cellular Pathology, University of Dundee, Dundee DD1 9SY, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC262654PMC
http://dx.doi.org/10.1128/mcb.23.23.8846-8861.2003DOI Listing
December 2003

Intrasteric regulation of MDM2.

Trends Biochem Sci 2003 Jul;28(7):346-9

Cancer Research UK laboratories, Department of Molecular and Cellular Pathology, University of Dundee, Dundee, Scotland, UK DD1 9SY.

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http://dx.doi.org/10.1016/S0968-0004(03)00140-3DOI Listing
July 2003

Hypoxia attenuates the p53 response to cellular damage.

Oncogene 2003 May;22(22):3431-40

The Cancer Research UK Laboratories, Department of Molecular and Cellular Pathology, The University of Dundee, Dundee, DD1 9SY, UK.

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http://dx.doi.org/10.1038/sj.onc.1206434DOI Listing
May 2003

DNA-dependent acetylation of p53 by the transcription coactivator p300.

J Biol Chem 2003 Apr 23;278(15):13431-41. Epub 2002 Dec 23.

Cancer Research UK Laboratories, Department of Molecular & Cellular Pathology, University of Dundee, Dundee DD1 9SY, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M211460200DOI Listing
April 2003

Drug discovery and p53.

Drug Discov Today 2003 Apr;8(8):347-55

Cancer Research UK Laboratories, Department of Surgery and Molecular Oncology, University of Dundee, Dundee, Scotland DD1 9SY, UK.

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April 2003

The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo.

J Biol Chem 2002 Aug 29;277(32):28446-58. Epub 2002 Mar 29.

Department of Molecular and Cellular Pathology, The Cancer Research UK Laboratories, The University of Dundee, Dundee DD1 9SY, Scotland.

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http://dx.doi.org/10.1074/jbc.M202296200DOI Listing
August 2002