Publications by authors named "Tayebeh Noori"

10 Publications

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Role of natural products for the treatment of Alzheimer's disease.

Eur J Pharmacol 2021 May 27;898:173974. Epub 2021 Feb 27.

Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. Electronic address:

Negative psychological and physiological consequences of neurodegenerative disorders represent a high social and health cost. Among the neurodegenerative disorders Alzheimer's disease (AD) is recognized as a leading neurodegenerative condition and a primary cause of dementia in the elderlys. AD is considered as neurodegenerative disorder that progressively impairs cognitive function and memory. According to current epidemiological data, about 50 milLion people worldwide are suffering from AD. The primary symptoms of AD are almost inappreciable and usually comprise forgetfulness of recent events. Numerous processes are involved in the development of AD, for example oxidative stress (OS) mainly due to mitochondrial dysfunction, intracellular the accumulation of hyperphosphorylated tau (τ) proteins in the form of neurofibrillary tangles, excessive the accumulation of extracellular plaques of beta-amyloid (Aβ), genetic and environmental factors. Running treatments only attenuate symptoms and temporarily reduce the rate of cognitive progression associated with AD. This means that most treatments focus only on controlLing symptoms, particularly in the initial stages of the disease. In the past, the first choice of treatment was based on natural ingredients. In this sense, diverse natural products (NPs) are capable to decrease the symptoms and alleviate the development of several diseases including AD attracting the attention of the scientific community and the pharmaceutical industry. Specifically, numerous NPs including flavonoids, gingerols, tannins, anthocyanins, triterpenes and alkaloids have been shown anti-inflammatory, antioxidant, anti-amyloidogenic, and anti-choLinesterase properties. This review provide a summary of the pathogenesis and the therapeutic goals of AD. It also discusses the available data on various plants and isolated natural compounds used to prevent and diminish the symptoms of AD.
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http://dx.doi.org/10.1016/j.ejphar.2021.173974DOI Listing
May 2021

Reinfection risk of novel coronavirus (COVID-19): A systematic ‎review of current evidence.

World J Virol 2020 Dec;9(5):79-90

Université Aix-Marseille, Institutde Neuro-physiopathologie (INP), UMR 7051, Faculté de ‎Pharmacie, 27 Bd Jean Moulin, Marseille 546789235, France.

Background: There is recently a concern regarding the reinfection and reactivation of previously reCoVered coronavirus disease 2019 (CoVID-19) patients.

Aim: To summarize the recent findings and reports of CoVID-19 reinfection in patients previously reCoVered from the disease.

Methods: This study was a systematic review of current evidence conducted in August 2020. The authors studied the probable reinfection risk of novel coronavirus (CoVID-19). We performed a systematic search using the keywords in online databases. The investigation adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist to ensure the reliability and validity of this study and results.

Results: We reviewed 31 studies. Eight studies described reCoVered patients with reinfection. Only one study reported reinfected patients who died. In 26 studies, there was no information about the status of the patients. Several studies indicated that reinfection is not probable and that post-infection immunity is at least temporary and short.

Conclusion: Based on our review, we concluded that a positive polymerase chain reaction retest could be due to several reasons and should not always be considered as reinfection or reactivation of the disease. Most relevant studies in positive retest patients have shown relative and probably temporary immunity after the reCoVery of the disease.
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http://dx.doi.org/10.5501/wjv.v9.i5.79DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747024PMC
December 2020

Identifying features of a mobile-based application for self-care of people living with T2DM.

Diabetes Res Clin Pract 2021 Jan 21;171:108544. Epub 2020 Nov 21.

Department of Nutrition, Khalkhal University of Medical Sciences, Khalkhal, Iran. Electronic address:

Introduction: Diabetes self-care requires support to empower patients to improve self-monitoring and maintain the necessary self-care behaviors. We aimed to identify features of a mobile-based application as a technology-based device for self-care of people living with T2DM.

Method: This study was conducted in two main phases in 2020. In the first phase, a literature review study was performed to identify the data elements and technical features of the T2DM self-care application. In the second phase, using the information obtained from the review of similar articles, a questionnaire was designed to validate identified requirements. The statistical population of the present study consisted of 22 endocrinologists and metabolic specialists.

Results: Identification of 55 data elements and technical features for mobile-based self-care application for people with T2DM, and according to the statistical population, 15data elements for demographic requirements, 16 data elements for clinical requirements, and 17 features for the technical capability of this app were selected.

Conclusion: Blood sugar monitoring, exercise, nutrition, weight monitoring, and educational capabilities were the most highlighted technical features of the T2DM self-care application. Software designers can use these requirements to design a self-care app for people with type-2 diabetes that can help manage and improve patients' health status.
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http://dx.doi.org/10.1016/j.diabres.2020.108544DOI Listing
January 2021

The role of glycogen synthase kinase 3 beta in multiple sclerosis.

Biomed Pharmacother 2020 Dec 18;132:110874. Epub 2020 Oct 18.

Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, 6734667149, Iran. Electronic address:

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that leads to progressive neurological disability due to axonal deterioration. Although MS presents profound heterogeneity in the clinical course, its underlying central mechanism is active demyelination and neurodegeneration associated with inflammation. Multiple autoimmune and neuroinflammatory pathways are involved in the demyelination process of MS. Analysis of MS lesions has shown that inflammatory genes are upregulated. Glycogen synthase kinase-3 (GSK-3) is part of the mitogen-activated protein kinase (MAPK) family and has important roles in many signaling cascades. GSK-3 is a highly conserved serine/threonine protein kinase expressed in both the central and the peripheral nervous systems. GSK-3 modulates several biological processes through phosphorylation of protein kinases, including cell signaling, neuronal growth, apoptosis and production of pro-inflammatory cytokines and interleukins, allowing adaptive changes in events such as cellular proliferation, migration, inflammation, and immunity. GSK-3 occurs in mammals in two isoforms GSK-3α and GSK-3β, both of which are common in the brain, although GSK-3α is found particularly in the cerebral cortex, cerebellum, striated hippocampus and Purkinje cells, while GSK-3β is found in all brain regions. In patients with chronic progressive MS, expression of GSK-3β is elevated in several brain regions such as the corpus callosum and cerebral cortex. GSK-3β inhibition may play a role in glial cell activation, reducing pathological pain induced by nerve injury by formalin injection. According to the role of GSK-3β in pathological conditions, the aim of this article is review of the role of GSK-3β in multiple sclerosis and inflammation of neurons.
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http://dx.doi.org/10.1016/j.biopha.2020.110874DOI Listing
December 2020

Olfactory and gustatory dysfunctions due to the coronavirus disease (COVID-19): a review of current evidence.

Eur Arch Otorhinolaryngol 2021 Feb 17;278(2):307-312. Epub 2020 Jun 17.

Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.

Introduction: It is reported that coronavirus disease (COVID-19) can affect the sense of smell and taste of infected people. The pathobiology of this virus is still incompletely known, and it is therefore important to explore the impact of COVID-19 infections on olfactory and gustatory functions. We aimed to review current evidence on olfactory and gustatory dysfunctions caused by COVID-19.

Methods: This study was a narrative review performed in 2020 to investigate the olfactory and gustatory dysfunctions of the COVID-19. We searched eight keywords in six databases to determine the related documents on the main objective of the study. To discover studies meeting the inclusion criteria, the authors screened the titles and abstracts of the identified articles. The appropriate studies were included and their results were discussed to make the final selection.

Results: We have studied 24 current articles on the olfactory and gustatory dysfunctions due to COVID-19. A review of current studies has shown that we have a surge in the spread of olfactory and gustatory dysfunctions that happened during the epidemic of COVID-19 infection. Most studies (95.8%) have confirmed the symptoms of anosmia in patients with SARS-CoV-2 infection. A review of current studies showed that, in addition to anosmia, evidence of ageusia and dysgeusia (parageusia) was also seen in patients with COVID-19.

Conclusion: The results of our study support recent reports that SARS-CoV-2 may infect oral and nasal tissues and cause olfactory and gustatory dysfunctions. These findings may aid future research on the diagnosis, prevention, and treatment of COVID-19 consequences.
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http://dx.doi.org/10.1007/s00405-020-06120-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297932PMC
February 2021

International Comparison of Thalassemia Registries: Challenges and Opportunities.

Acta Inform Med 2019 Mar;27(1):58-63

Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.

Background: Patient registries use standardized methods to systematically gather uniform data for specific groups of patients managed in clinical practice to evaluate specified outcomes.

Aim: The objective of this study was to identify and describe structures of the identified thalassemia registries in worldwide and summarize their key characteristics.

Methods: We reviewed the literature on thalassemia registries. A search of PubMed, Scopus, ProQuest, and Science Direct databases was conducted in September 2018. We also reviewed the existing thalassemia registry websites in different countries. The keywords used to our search were as follows: Thalassemia, Hemoglobinopathy, Registry, Database, and Registration System. Some features such as the name of registry, funding source, objectives of the registry, minimum data set, and methods of data collection were determined.

Results: We identified 16 thalassemia registries operating on a multinational, national, or regional level between1984 and 2016. Most of these aimed to improve the diagnosis and management of control programs. Government funding was the most common funding source for registries. Furthermore, the most common method of data submission was Web-based data entry. The data were entered by a member of the clinical team or a nominated data manager.

Conclusion: Registries provide a positive return on investment; their establishment and maintenance require ongoing support by government, policy makers, research funding bodies, clinicians, thalassemia patients and their caregivers. However, the results of research suggest the establishment of an international network for coordination and collaboration between thalassemia registries.
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http://dx.doi.org/10.5455/aim.2019.27.58-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511274PMC
March 2019

Design of Infertility Monitoring System: Minimum Data Set Approach.

J Med Life 2019 Jan-Mar;12(1):56-64

Health Information Management Department, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.

Reproductive health is vital for human and infertility is also one of the most important challenges in the reproductive system. Infertility is one of the most common chronic health disorders, regardless of age. The Minimum Data Set (MDS) helps to manage infertility by monitoring and evaluating infertility interventions based on collecting data. The development of MDS is an essential objective in order to implement an infertility monitoring system for the creation of standardized and effective data management through the provision of comprehensive and identical data elements for infertility. This is a descriptive cross-sectional study conducted in 2017. The data has been collected from infertility clinics in the world, as well as WHO, CDC, ASRM, and ESHRE reports. In order to decide on data elements, the Delphi technique was used using a questionnaire that contained data elements which were distributed among 12 experts including one reproductive endocrinology and infertility fellow, six obstetrician-gynecologists, two reproductive biologists, two urologists and one community medicine specialist using the 5 point Likert scale. The questionnaire was divided into two categories: managerial and clinical, each with 4 sections, and 60 and 940 data elements, respectively. MDS is an essential tool for evaluating the infertility process. Using this tool will provide an opportunity to develop a set of quality care criteria that can be used to ensure the quality of infertility care.
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http://dx.doi.org/10.25122/jml-2018-0071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527411PMC
July 2019

Identifying and validating requirements of telemental health services for Iranian veterans.

J Family Med Prim Care 2019 Mar;8(3):1216-1221

Department of Health Information Technology, Khalkhal University of Medical Sciences, Khalkhal, Iran.

Background: The ability of timely access to mental health care is very important for combat veterans that are facing many barriers such as living in rural and remote areas and the lack of integration. Telemental health services improve the veterans' health situation by providing mental health care from a distance. We aimed to identify the telemental health service requirements for Iranian veterans and validate them from the perspective of the statistical population.

Methods: This descriptive cross-sectional study was conducted in 2018. In the first phase, a review was conducted in relevant databases, such as PubMed, Scopus, Ovid, Ebsco, and Web of Science. In the second phase, veterans, mental health providers, and telemedicine experts were consulted to validating of the identified telemental health service requirements by a researcher-made questionnaire. Analysis of collecting data was done using SPSS software.

Results: By full-text reviewing of 15 related articles, the identified elements were justified in 2 main categories and 24 subcategories including telemental health services (17 items) and telemental health requirements (7 items). According to the findings, the highest score was related to "save health-care costs" (4.47) and "reduce transportation-related problems" (4.47). Moreover, the "feasible alternative to face-to-face care" (2.22) obtained the lowest score from the perspective of the statistical population.

Conclusion: Due to the importance of accessibility and patient-based mental health services, more studies are needed to investigate the point of views of patients and specialists to better understand the concerns and barriers to the implementation and use of telemental health services.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_324_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482756PMC
March 2019

Identifying and Prioritizing of Data Elements for the Ophthalmology Health Smart Card.

Acta Inform Med 2018 Dec;26(4):245-248

School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.

Background: Recently, with the development of information and communication technology in the healthcare industry, the tools of this technology have different applications such as Health Smart Card in this area. The main application of health smart card in the field of ophthalmology is providing demographic and clinical information for different people. Therefore, this study was done to identify and prioritize the data elements of the ophthalmology health smart card.

Methods: This study was a descriptive-development one that was done in 2017. A review was conducted in relevant databases including PubMed, Web of knowledge, Science direct, and Web of Science to identify appropriate related sources. In the second phase, the ophthalmology specialists and health information managers (20) in RassolAkram, Farabi and Noor Eye Hospital consulted by a questionnaire for health smart card requirements. This study carried out in Iran. Collected data were analyzed by descriptive methods in SPSS software version 19.

Results: Two categories of demographic and clinical data requirements for health smart card were determined. Patient ID, Occupation, and National Code were the most important demographic requirements of ophthalmology health card. Furthermore, clinical data elements of the ophthalmology health smart card were identified in three categories: Corneal Tests, Retinal Tests, Glaucoma Tests, and Associated Conditions.

Conclusion: Using the identified data elements, it is possible to design and implement an ophthalmology health smart card. Developing an ophthalmology health smart card is expected to progress of information retrieve, facilitate communication of healthcare organizations and improve healthcare quality.
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http://dx.doi.org/10.5455/aim.2018.26.245-248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311119PMC
December 2018

Web and Mobile Based HIV Prevention and Intervention Programs Pros and Cons - A Review.

Stud Health Technol Inform 2017 ;236:319-327

Department of Health Information Management, Tehran University of Medical Sciences, Tehran, Iran.

Background: With the increasing growth of HIV positive people the use of information and communication technologies (ICT) can play an important role in controlling the spread of the AIDS. Web and Mobile are the new technologies that young people take advantage from them.

Objectives: In this study a review to investigate the web and mobile based HIV prevention and intervention programs was carried out.

Methods: A scoping review was conducted including PubMed, Science direct, Web of Science and Proquest to find relevant sources that published in 2009 to 2016. To identify published, original research that reported the web and mobile-based HIV prevention and intervention programs, an organized search was conducted with the following search keywords in combination: HIV, AIDS, m-Health, Mobile phone, Cell phone, Smartphone, Mobile health, internet, and web.

Results: Using the employed strategies, 173 references retrieved. Searched articles were compared based on their titles and abstracts. To identify duplicated articles, the title and abstracts were considered and 101 duplicated references were excluded. By going through the full text of related papers, 35 articles were found to be more related to the questions of this paper from which 72 final included.

Conclusion: The advantages of web and mobile-based interventions include the possibility to provide constancy in the delivery of an intervention, impending low cost, and the ability to spread the intervention to an extensive community. Online programs such as Chat room-based Education program, Web-based therapeutic education system, and Online seek information can use for HIV/AIDS prevention. To use of mobile for HIV/AIDS prevention and intervention, programs including in: Health system focused applications, Population health focused applications, and Health messaging can be used.
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April 2018