Taye Balcha, MD, MPH, PhD - Lund University

Taye Balcha

MD, MPH, PhD

Lund University

ORCID logohttps://orcid.org/0000-0001-8882-5936

Taye Balcha, MD, MPH, PhD - Lund University

Taye Balcha

MD, MPH, PhD

Introduction

Primary Affiliation: Lund University

Publications

36Publications

583Reads

4Profile Views

The Unmet Need: Low Performance of Laboratory Professionals in Malaria Microscopy, Oromia Regional State, Ethiopia.

American Journal of Tropical Medicine and Hygiene

Ethiopia aims to diagnose and treat all clinical malaria within 24 hours of fever onset in its stride to eliminate the disease by 2030. Microscopy remains to be the mainstay for diagnosis at the health center and hospital level. Continuous evaluation and performance upgrading of malaria microscopists is one of the cornerstones in this effort. We assessed the performance of malaria microscopists compared with reference readers in diagnosing, identifying the species, and quantifying parasitemia. A total of 174 microscopists were enrolled from health facilities located in 86 districts in Oromia region (Ethiopia) from January 2017 to June 2018. Panel slides with known Plasmodium species, diagnostic blood stage, and parasite density were prepared by the reference readers. Sociodemographics, education, in-service training, and routine practice of participants were captured. Sensitivity, specificity, percent agreement, and kappa score were calculated. An overall low performance was observed that could threaten the malaria diagnostic service. Of all the slides distributed (1,218), only 17.0% of the positive and 30.0% of the negative slides were correctly identified and 22.4% were correctly quantified. Compared with the reference readers, participants had lower competence in diagnosing (74.3% agreement and kappa 0.45) and identifying the species (71.2% agreement and kappa 0.40). Two-fifths of the participants were graded as "in training" with respect to identifying the species (41.0%) and the diagnostic stages (40.0%). An in-service training/retraining and supportive supervision are needed to raise and maintain the competence of microscopists in settings with a recent decline in malaria transmission and aiming for ultimate elimination of the disease.

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November 2019

Impact Factor 2.600

Prevalence of Celiac Disease Autoimmunity in Ethiopian Pregnant Women: A Cross Sectional Study from the Oromia region

International Journal of Celiac Disease

Abstract  Celiac disease is a chronic small bowel disease induced by ingestion of gluten in genetically susceptible individuals affecting 1% among Caucasians in the Western world. The prevalence of celiac disease is still unknown in most developing countries, especially in Africa which suffer from lack of resources to perform screening of the general population. The aim of this study was to determine the prevalence of celiac disease autoimmunity in women undergoing antenatal care in selected Ethiopian health institutes. A total of 1942 pregnant women were included at median 25 (range 15-45) years of age who were attending antenatal care at 14 health centers of Central and South-East Oromia regional state of Ethiopia. Serum samples were analyzed for both IgA and IgG autoantibodies against tissue transglutaminase (tTG) using radioligand binding assays. Celiac disease autoimmunity defined as testing positive for both of IgA-tTG and IgG-tTG. In all, 4 of  1942 (0.2%) were positive for IgG-tTG of whom one participant (0.05%) was positive for both IgA-tTG and IgG-tTG and defined as having celiac disease autoimmunity. Based on these results, it was concluded that celiac disease autoimmunity is expected to be less common among the female adult Ethiopian population compared with the expected prevalence in Caucasians. 



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September 2019
1 Read

Validation of the Viral Load Testing Criteria - an algorithm for targeted viral load testing in HIV-positive adults receiving antiretroviral therapy.

Trop Med Int Health 2019 03 24;24(3):356-362. Epub 2019 Jan 24.

Clinical Infection Medicine, Department of Translational Medicine, Lund University, Malmö, Sweden.

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http://doi.wiley.com/10.1111/tmi.13201
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http://dx.doi.org/10.1111/tmi.13201DOI Listing
March 2019
5 Reads
2.329 Impact Factor

Towards achieving the fast-track targets and ending the epidemic of HIV/AIDS in Ethiopia: Successes and challenges.

Int J Infect Dis 2019 Jan 1;78:57-64. Epub 2018 Nov 1.

School of Public Health, the University of Queensland, Brisbane, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S12019712183457
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http://dx.doi.org/10.1016/j.ijid.2018.10.022DOI Listing
January 2019
25 Reads
2.330 Impact Factor

Establishing Health Biotech and Enhancing Local Manufacturing of Pharmaceuticals in Sub-Saharan Africa.

Authors:
Taye T Balcha

Glob Adv Health Med 2018 12;7:2164956118809685. Epub 2018 Nov 12.

Office of the Director General, Armauer Hansen Research Institute, Addis Ababa, Ethiopia.

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http://dx.doi.org/10.1177/2164956118809685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236473PMC
November 2018
24 Reads

Development of an algorithm for determination of the likelihood of virological failure in HIV-positive adults receiving antiretroviral therapy in decentralized care.

Glob Health Action 2017 ;10(1):1371961

a Clinical Infection Medicine, Department of Translational Medicine , Lund University , Malmö , Sweden.

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http://dx.doi.org/10.1080/16549716.2017.1371961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645660PMC
September 2018
2 Reads
1.646 Impact Factor

Growth pattern in Ethiopian infants - the impact of exposure to maternal HIV infection in relation to socio-economic factors.

Glob Health Action 2017 ;10(1):1296726

a Department of Translational Medicine, Section for Infectious Diseases , Lund University , Malmö , Sweden.

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http://dx.doi.org/10.1080/16549716.2017.1296726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496093PMC
September 2018
33 Reads
1.646 Impact Factor

Factors Associated with Early Mortality in HIV-Positive Men and Women Investigated for Tuberculosis at Ethiopian Health Centers.

PLoS One 2016 7;11(6):e0156602. Epub 2016 Jun 7.

Infectious Diseases Research Unit, Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156602PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896420PMC
July 2017
3 Reads
3.234 Impact Factor

Performance of the Antiretroviral Treatment Program in Ethiopia, 2005-2015: strengths and weaknesses toward ending AIDS.

Int J Infect Dis 2017 Jul 19;60:70-76. Epub 2017 May 19.

Institute of Tropical Medicine, Department of Public Health, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.ijid.2017.05.012DOI Listing
July 2017
13 Reads
2.330 Impact Factor

Retention in care among HIV-positive patients initiating second-line antiretroviral therapy: a retrospective study from an Ethiopian public hospital clinic.

Glob Health Action 2016 12;9:29943. Epub 2016 Jan 12.

Section for Infectious Diseases, Institution of Clinical Sciences, Lund University, Malmö, Sweden;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712321PMC
http://dx.doi.org/10.3402/gha.v9.29943DOI Listing
August 2016
8 Reads
1.646 Impact Factor

Pro-poor pathway towards universal health coverage: lessons from Ethiopia.

J Glob Health 2016 Jun;6(1):010305

Ministry of Foreign Affairs, Addis Ababa, Ethiopia.

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http://dx.doi.org/10.7189/jogh.06.010305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920007PMC
June 2016
3 Reads

Plasma Levels of Neopterin and C-Reactive Protein (CRP) in Tuberculosis (TB) with and without HIV Coinfection in Relation to CD4 Cell Count.

PLoS One 2015 2;10(12):e0144292. Epub 2015 Dec 2.

Infectious Disease Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668010PMC
June 2016
17 Reads
3.234 Impact Factor

Barriers to antiretroviral treatment in ethiopia: a qualitative study.

J Int Assoc Physicians AIDS Care (Chic) 2011 Mar-Apr;10(2):119-25. Epub 2011 Feb 11.

Department of Clinical Sciences, Lund University, University Hospital Malmo, Malmo, Sweden, Oromia Regional Health Bureau, Addis Ababa, Ethiopia.

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http://dx.doi.org/10.1177/1545109710387674DOI Listing
April 2016
5 Reads

Strategic Challenges of PMTCT Program Implementation in Ethiopia.

J Int Assoc Physicians AIDS Care (Chic) 2011 May-Jun;10(3):187-92. Epub 2011 Apr 20.

Social Medicine & Global Health, University Hospital Malmo, Malmo, Sweden,

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http://dx.doi.org/10.1177/1545109710369935DOI Listing
April 2016
6 Reads

Model villages: a platform for community-based primary health care.

Lancet Glob Health 2016 Feb 21;4(2):e78-9. Epub 2015 Dec 21.

World Health Organization, Geneva, Switzerland.

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http://dx.doi.org/10.1016/S2214-109X(15)00301-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642843PMC
February 2016
14 Reads

High rates of viral suppression in a cohort of HIV-positive adults receiving ART in Ethiopian health centers irrespective of concomitant tuberculosis.

J Int AIDS Soc 2014 2;17(4 Suppl 3):19612. Epub 2014 Nov 2.

Infectious Diseases Research Unit, Department of Clinical Sciences, Malmö, Faculty of Medicine, Lund University, Lund, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224826PMC
http://dx.doi.org/10.7448/IAS.17.4.19612DOI Listing
January 2016
69 Reads
5.090 Impact Factor

Outcome of tuberculosis treatment in HIV-positive adults diagnosed through active versus passive case-finding.

Glob Health Action 2015 27;8:27048. Epub 2015 Mar 27.

Infectious Disease Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377322PMC
http://dx.doi.org/10.3402/gha.v8.27048DOI Listing
January 2016
16 Reads
1.646 Impact Factor

Local innovations and country ownership for sustainable development.

Bull World Health Organ 2015 Nov;93(11):742

Ministry of Health, Addis Ababa, PO Box 1234, Ethiopia .

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http://dx.doi.org/10.2471/BLT.15.164483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622164PMC
November 2015
2 Reads
5.089 Impact Factor

Screening for cryptococcal antigenemia using the lateral flow assay in antiretroviral therapy-naïve HIV-positive adults at an Ethiopian hospital clinic.

BMC Res Notes 2015 Nov 23;8:702. Epub 2015 Nov 23.

Infectious Diseases Research Unit, Department of Clinical Sciences, Faculty of Medicine, Lund University, Ruth Lundskogs gata 3, 21428, Malmö, Sweden.

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http://dx.doi.org/10.1186/s13104-015-1707-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656181PMC
November 2015
26 Reads

CD4 cell levels during treatment for tuberculosis (TB) in Ethiopian adults and clinical markers associated with CD4 lymphocytopenia.

PLoS One 2013 16;8(12):e83270. Epub 2013 Dec 16.

Infectious Diseases Research Unit, Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0083270PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865172PMC
October 2014
24 Reads
3.234 Impact Factor

Detection of lipoarabinomannan in urine for identification of active tuberculosis among HIV-positive adults in Ethiopian health centres.

Trop Med Int Health 2014 Jun 29;19(6):734-742. Epub 2014 Mar 29.

Infectious Disease Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1111/tmi.12308DOI Listing
June 2014
9 Reads
2.329 Impact Factor

Decentralised paediatric HIV care in Ethiopia: a comparison between outcomes of patients managed in health centres and in a hospital clinic.

Glob Health Action 2013 Nov 11;6:22274. Epub 2013 Nov 11.

Infectious Disease Research Unit, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825866PMC
http://dx.doi.org/10.3402/gha.v6i0.22274DOI Listing
November 2013
18 Reads
1.646 Impact Factor

The impact of indoor residual spraying on malaria incidence in East Shoa Zone, Ethiopia.

Glob Health Action 2012 16;5:11619. Epub 2012 Apr 16.

Oromia Regional Health Bureau, Addis Ababa, Ethiopia.

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http://dx.doi.org/10.3402/gha.v5i0.11619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329214PMC
July 2012
7 Reads
1.646 Impact Factor

Outcomes of antiretroviral treatment: a comparison between hospitals and health centers in Ethiopia.

J Int Assoc Physicians AIDS Care (Chic) 2010 Sep-Oct;9(5):318-24

Lund University, Social Medicine & Global Health, University Hospital, Malmo, Sweden.

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http://dx.doi.org/10.1177/1545109710367518DOI Listing
December 2010
2 Reads

Top co-authors

Sten Skogmar
Sten Skogmar

Lund University

11
Anton Reepalu
Anton Reepalu

Lund University

10
Patrik Medstrand
Patrik Medstrand

Lund University

5
Niclas Winqvist
Niclas Winqvist

Lund University

4
Zelalem Habtamu Jemal
Zelalem Habtamu Jemal

Oromia Regional Health Bureau

4
Teun Bousema
Teun Bousema

London School of Hygiene and Tropical Medicine

3
Chris Drakeley
Chris Drakeley

London School of Hygiene and Tropical Medicine

3