Tatsuhiro Shibata

Tatsuhiro Shibata

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Tatsuhiro Shibata

Publications by authors named "Tatsuhiro Shibata"

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Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone.

Mod Pathol 2019 Dec 8;32(12):1751-1761. Epub 2019 Jul 8.

Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41379-019-0318-5DOI Listing
December 2019

KMT2A (MLL) fusions in aggressive sarcomas in young adults.

Histopathology 2019 Oct 8;75(4):508-516. Epub 2019 Aug 8.

Division of Cancer Genomics, National Cancer Centre Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1111/his.13926DOI Listing
October 2019

Sarcoma with MGA-NUTM1 fusion in the lung: an emerging entity.

Virchows Arch 2019 Aug 5. Epub 2019 Aug 5.

Department of Diagnostic Pathology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s00428-019-02623-8DOI Listing
August 2019

Morphine Use for Heart Failure Patients with Renal Insufficiency.

J Palliat Med 2019 Jun;22(6):617-618

1 Department of Palliative Care, Iizuka Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.1089/jpm.2019.0127DOI Listing
June 2019

Multifocal origin of occupational cholangiocarcinoma revealed by comparison of multilesion mutational profiles.

Carcinogenesis 2019 Jun 20. Epub 2019 Jun 20.

Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwanoha, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/carcin/bgz120DOI Listing
June 2019

The Essence of Palliative Care Is Best Viewed as the "Problematization".

J Palliat Med 2019 01;22(1)

3 Department of Cardiology, Himeji Cardiovascular Center, Himeji, Japan.

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http://dx.doi.org/10.1089/jpm.2018.0501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362320PMC
January 2019

Integrated genetic and epigenetic analysis of myxofibrosarcoma.

Nat Commun 2018 07 17;9(1):2765. Epub 2018 Jul 17.

Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1038/s41467-018-03891-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050269PMC
July 2018

Molecular genomic landscapes of hepatobiliary cancer.

Cancer Sci 2018 May 28;109(5):1282-1291. Epub 2018 Apr 28.

Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.13582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980207PMC
May 2018

Coronary Artery Ectasia Predicts Future Cardiac Events in Patients With Acute Myocardial Infarction.

Arterioscler Thromb Vasc Biol 2017 12 19;37(12):2350-2355. Epub 2017 Oct 19.

From the Department of Cardiovascular Medicine (T.D., Y.K., T. Noguchi, T. Nakashima, S.K., K. Nakao, M.F., T. Nagai, T.K., Y.T., Y.A., T.A., K.K., Y.G., S.Y.), Department of Pediatric Cardiology (E.T.), and Department of Statistics and Data Analysis, Center for Cerebral and Cardiovascular Disease Information (M.N., K.N.), National Cerebral and Cardiovascular Center, Suita, Japan; Department of Advanced Cardiovascular Medicine (T.D., S.Y.) and Department of Cardiovascular Medicine (H.S.), Tohoku University Graduate School of Medicine, Sendai, Japan; and Division of Cardiovascular Medicine, Department of Internal Medicine, Kurume University School of Medicine, Japan (T.S.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309683DOI Listing
December 2017

Highly recurrent H3F3A mutations with additional epigenetic regulator alterations in giant cell tumor of bone.

Genes Chromosomes Cancer 2017 10 27;56(10):711-718. Epub 2017 Jul 27.

Division of Cancer Genomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1002/gcc.22469DOI Listing
October 2017

Clinical Utility of Circulating Tumor DNA for Molecular Assessment and Precision Medicine in Pancreatic Cancer.

Adv Exp Med Biol 2016 ;924:13-17

Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1007/978-3-319-42044-8_3DOI Listing
September 2017

CIC break-apart fluorescence in-situ hybridization misses a subset of CIC-DUX4 sarcomas: a clinicopathological and molecular study.

Histopathology 2017 Sep 5;71(3):461-469. Epub 2017 Jul 5.

Department of Pathology and Clinical Laboratories, National Cancer Centre Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/his.13252DOI Listing
September 2017

NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma.

Hum Pathol 2017 07 8;65:225-230. Epub 2017 Feb 8.

Department of Surgical Pathology, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido 060-8543, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2017.01.012DOI Listing
July 2017

Generation of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.

Sci Rep 2017 07 5;7(1):4712. Epub 2017 Jul 5.

Department of Innovative Seeds Evaluation, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1038/s41598-017-04967-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498486PMC
July 2017

The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells.

Cell Rep 2017 05;19(5):981-994

Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.04.017DOI Listing
May 2017

Genomic and transcriptomic analysis of imatinib resistance in gastrointestinal stromal tumors.

Genes Chromosomes Cancer 2017 04 23;56(4):303-313. Epub 2017 Jan 23.

Department of Bioinformatics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1002/gcc.22438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324566PMC
April 2017

Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer.

Pancreas 2017 03;46(3):335-340

From the *Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo; †Division of Genome Biology, National Cancer Center Research Institute, Tokyo; ‡Department of Gastroenterology and Hepatology, Hokkaido University Graduate School of Medicine, Sapporo; §Department of Cancer Chemotherapy, Hokkaido University Hospital Cancer Center, Sapporo; ∥Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo; Divisions of ¶Genetics and #Cancer Genomics, National Cancer Center Research Institute, Tokyo; and **Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1097/MPA.0000000000000760DOI Listing
March 2017

Establishment of various biliary tract carcinoma cell lines and xenograft models for appropriate preclinical studies.

World J Gastroenterol 2016 Oct;22(40):9035-9038

Hidenori Ojima, Division of Molecular Pathology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.3748/wjg.v22.i40.9035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083809PMC
October 2016

NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth.

Cancer Res 2016 05 28;76(10):3088-96. Epub 2016 Mar 28.

Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1584DOI Listing
May 2016

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.

Int J Oncol 2015 3;46(6):2389-98. Epub 2015 Apr 3.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.3892/ijo.2015.2951DOI Listing
January 2016

Current and future molecular profiling of cancer by next-generation sequencing.

Jpn J Clin Oncol 2015 Oct 19;45(10):895-9. Epub 2015 Aug 19.

Laboratory of Molecular Medicine, Institute of Medical Science, University of Tokyo, Tokyo Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan

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http://dx.doi.org/10.1093/jjco/hyv122DOI Listing
October 2015

SRY and OCT4 Are Required for the Acquisition of Cancer Stem Cell-Like Properties and Are Potential Differentiation Therapy Targets.

Stem Cells 2015 Sep 23;33(9):2652-63. Epub 2015 Jun 23.

Department of Biological Sciences and Technology, Faculty of Industrial Science and Technology, Tokyo University of Science, Niijuku, Katsushika-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/stem.2059DOI Listing
September 2015

Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.

Mol Cancer Ther 2015 Sep 3;14(9):1985-93. Epub 2015 Jul 3.

Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan. Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0069DOI Listing
September 2015

Prevalence, Clinical Features, and Prognosis of Acute Myocardial Infarction Attributable to Coronary Artery Embolism.

Circulation 2015 Jul 25;132(4):241-50. Epub 2015 Jun 25.

From Departments of Cardiovascular Medicine (T.S., S.K., T. Noguchi, Y.A., T.K., T. Nagai, K. Nakao, M.F., K.K., T.A., Y.G., H.O., S.Y.), Stroke and Cerebrovascular Disease (T.T., K. Nagatsuka), Pathology (H.I.-U.), and Preventive Medicine and Epidemiologic Informatics, Center for Cerebral and Cardiovascular Disease Information (K. Nishimura, Y.M.), National Cerebral and Cardiovascular Center, Suita, Japan.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.015134DOI Listing
July 2015

Expression and clinical significance of genes frequently mutated in small cell lung cancers defined by whole exome/RNA sequencing.

Carcinogenesis 2015 Jun 11;36(6):616-21. Epub 2015 Apr 11.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan, Cancer Genome Biology Group, Institute of Predictive and Personalized Medicine of Cancer, 08916 Barcelona, Spain

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http://dx.doi.org/10.1093/carcin/bgv026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462675PMC
June 2015

Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.

Neuro Oncol 2015 Apr 10;17(4):555-65. Epub 2014 Oct 10.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan (M.K., Y.S., I.S., R.S., T.K., T.T.); Department of Gene Expression Regulation, Institute of Development, Aging, and Cancer, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan (T.H., S.M., M.D., H.K., K.T., H.M.); Center for Radioisotope Sciences, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan (T.H.); Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan (S.M., K.T., M.Y.); Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan (T.S.); Department of Pathology, Tohoku University Hospital, Sendai, Miyagi, Japan (M.W.); Department of Pathology and Laboratory Medicine, Sendai Medical Center, Sendai, Miyagi, Japan (H.S.); Department of Neurosurgery, Miyagi Cancer Center, Natori, Miyagi, Japan (Y.Y.).

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http://dx.doi.org/10.1093/neuonc/nou282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483074PMC
April 2015

Comprehensive DNA adduct analysis reveals pulmonary inflammatory response contributes to genotoxic action of magnetite nanoparticles.

Int J Mol Sci 2015 Feb 4;16(2):3474-92. Epub 2015 Feb 4.

Division of Carcinogenesis and Prevention, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.3390/ijms16023474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346908PMC
February 2015

Translational cancer research: balancing prevention and treatment to combat cancer globally.

J Natl Cancer Inst 2015 Jan 16;107(1):353. Epub 2014 Dec 16.

Director's Office, Sections of Mechanisms of Carcinogenesis and Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, France (CPW, ZH, RH, AS); National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA (JRB); Department of Pathology, Erasmus Medical Centre, Rotterdam, The Netherlands (BWDdJ); Department of Medical Epidemiology & Biostatistics, BioBanking & Molecular Resource Infrastructure, Karolinska Institute, Stockholm, Sweden (JD); Radiation Medicine Center, Karolinska Institute, Stockholm, Sweden (CvG); Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA (JDG); Department of Surgery and Cancer, Imperial College London, London, UK (EH); Danish Cancer Society Research Centre, Copenhagen, Denmark (JHO); Cancer Center Karolinska, Karolinska University Hospital Solna, Stockholm, Sweden (UR); Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan (TS); School of Public Health, University of California, Berkeley, CA, USA (MTS); Division of Preventive Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany (CU); Department of Epidemiology & Biostatistics, Imperial College London, London, UK (PV); Dalla Lana School of Public Health, University of Toronto, Toronto, Canada (JM).

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http://dx.doi.org/10.1093/jnci/dju353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334834PMC
January 2015

A novel CIC-FOXO4 gene fusion in undifferentiated small round cell sarcoma: a genetically distinct variant of Ewing-like sarcoma.

Am J Surg Pathol 2014 Nov;38(11):1571-6

Departments of *Surgical Pathology ∥Pathology ¶Orthopedic Surgery, Sapporo Medical University School of Medicine, Sapporo †Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo Departments of ‡Diagnostic Pathology §Hematology and Medical Oncology, Japan Labour Health and Welfare Organization, Kanto Rosai Hospital, Kanagawa, Japan.

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http://pdfs.journals.lww.com/ajsp/2014/11000/A_Novel_CIC_FOX
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000286DOI Listing
November 2014

A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.

Carcinogenesis 2014 Aug 24;35(8):1840-6. Epub 2014 May 24.

Division of Virology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan,

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http://dx.doi.org/10.1093/carcin/bgu112DOI Listing
August 2014

Wide local extension and higher proliferation indices are characteristic features of symptomatic lobular neoplasias (LNs) and LNs with an early invasive component.

Histopathology 2014 Jun 8;64(7):994-1003. Epub 2014 Mar 8.

Department of Basic Pathology, National Defence Medical College, Tokorozawa, Japan; Department of Pathology and Clinical Laboratories, National Cancer Centre Hospital, Tokyo, Japan.

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http://doi.wiley.com/10.1111/his.12356
Publisher Site
http://dx.doi.org/10.1111/his.12356DOI Listing
June 2014

Exploration of liver cancer genomes.

Nat Rev Gastroenterol Hepatol 2014 Jun 28;11(6):340-9. Epub 2014 Jan 28.

Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo 153-8904, Japan.

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http://www.nature.com/articles/nrgastro.2014.6
Publisher Site
http://dx.doi.org/10.1038/nrgastro.2014.6DOI Listing
June 2014

Axitinib (AG-013736), an oral specific VEGFR TKI, shows potential therapeutic utility against cholangiocarcinoma.

Jpn J Clin Oncol 2014 Jun 21;44(6):570-8. Epub 2014 Apr 21.

Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo

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http://dx.doi.org/10.1093/jjco/hyu045DOI Listing
June 2014

Immunohistochemical detection of ROS1 is useful for identifying ROS1 rearrangements in lung cancers.

Mod Pathol 2014 May 1;27(5):711-20. Epub 2013 Nov 1.

Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1038/modpathol.2013.192DOI Listing
May 2014

Molecular mechanisms underlying oncogenic RET fusion in lung adenocarcinoma.

J Thorac Oncol 2014 May;9(5):622-30

*Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; †Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan; ‡Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan; §Division of Genetics, National Cancer Center Research Institute, Tokyo, Japan; and ¶Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000135DOI Listing
May 2014

Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.

Hepatology 2014 Apr 18;59(4):1427-34. Epub 2014 Feb 18.

Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1002/hep.26890DOI Listing
April 2014

Emerging drugs for biliary cancer.

Expert Opin Emerg Drugs 2014 Mar 20;19(1):11-24. Epub 2013 Dec 20.

National Cancer Center Hospital, Department of Hepatobiliary and Pancreatic Oncology , 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 , Japan +81 3 3542 2511 ; +81 3 3542 3815 ;

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http://dx.doi.org/10.1517/14728214.2014.870553DOI Listing
March 2014

Inflammatory myofibroblastic tumour of the lung with a novel PPFIBP1-ALK fusion variant.

Histopathology 2013 Dec 19;63(6):881-3. Epub 2013 Aug 19.

Division of Pathology and Clinical Laboratories, National Cancer Centre Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/his.12218DOI Listing
December 2013

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer.

Genes Chromosomes Cancer 2013 Sep 28;52(9):802-16. Epub 2013 May 28.

Division of Multistep Carcinogenesis, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1002/gcc.22076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806277PMC
September 2013

Histological factors for accurately predicting first locoregional recurrence of invasive ductal carcinoma of the breast.

Cancer Sci 2013 Sep 25;104(9):1252-61. Epub 2013 Jul 25.

Diagnostic Pathology Section, Medical Support and Partnership Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.12217DOI Listing
September 2013

Aberrant anaplastic lymphoma kinase expression in high-grade pulmonary neuroendocrine carcinoma.

J Clin Pathol 2013 Aug 25;66(8):705-7. Epub 2013 Apr 25.

Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1136/jclinpath-2012-201329DOI Listing
August 2013

Signatures of mutational processes in human cancer.

Nature 2013 Aug 14;500(7463):415-21. Epub 2013 Aug 14.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776390PMC
August 2013

Identification of a lung adenocarcinoma cell line with CCDC6-RET fusion gene and the effect of RET inhibitors in vitro and in vivo.

Cancer Sci 2013 Jul 12;104(7):896-903. Epub 2013 May 12.

Division of Translational Research, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1111/cas.12175DOI Listing
July 2013