Tatsuhiko Kodama

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Tatsuhiko Kodama

Publications by authors named "Tatsuhiko Kodama"

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100Publications

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The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.

Mol Cell Biol 2018 Jun 4. Epub 2018 Jun 4.

Department of Diabetes and Metabolic Diseases Department of Molecular Sciences on Diabetes Graduate School of Medicine, Translational Systems Biology and Medicine Initiative (TSBMI) Research Center for Advanced Science and Technology the University of Tokyo, Tokyo, Japan; Department of Home Economics, Otsuma Women's University, Tokyo, Japan

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June 2018

Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis.

Nature 2018 Mar 28;555(7695):260-264. Epub 2018 Feb 28.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0032, Japan.

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March 2018

Overexpression of p54/NONO induces differential splicing and contributes to castration-resistant prostate cancer growth.

Oncotarget 2018 Feb 8;9(12):10510-10524. Epub 2018 Jan 8.

Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, Tokyo 153-8904, Japan.

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February 2018

Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation.

Mol Cell Biol 2017 Sep 28;37(18). Epub 2017 Aug 28.

Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, Tokyo, Japan

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September 2017

Epiregulin-blocking antibody inhibits epiregulin-dependent EGFR signaling.

Biochem Biophys Res Commun 2017 07 6;489(1):83-88. Epub 2017 Mar 6.

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8904, Japan. Electronic address:

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July 2017

Degradation of human Lipin-1 by BTRC E3 ubiquitin ligase.

Biochem Biophys Res Commun 2017 06 5;488(1):159-164. Epub 2017 May 5.

Laboratory of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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June 2017

Visualization of ligand-induced G-protein activation in chemotaxing cells.

FASEB J 2017 03 23;31(3):910-919. Epub 2016 Nov 23.

Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, University of Tokyo, Tokyo, Japan; and

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March 2017

Extracellular Acidic pH Activates the Sterol Regulatory Element-Binding Protein 2 to Promote Tumor Progression.

Cell Rep 2017 02;18(9):2228-2242

The Translational Systems Biology and Medicine Initiative (TSBMI), Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan; Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan. Electronic address:

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February 2017

Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.

Atherosclerosis 2016 06 26;249:36-43. Epub 2016 Feb 26.

Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan. Electronic address:

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June 2016

PGE2 induced in and released by dying cells functions as an inhibitory DAMP.

Proc Natl Acad Sci U S A 2016 Apr 21;113(14):3844-9. Epub 2016 Mar 21.

Department of Molecular Immunology, Institute of Industrial Science, The University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505, Japan; Max Planck-The University of Tokyo Center for Integrative Inflammology, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505, Japan;

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April 2016

Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4.

Biochem Biophys Res Commun 2016 Jan 20;469(4):797-802. Epub 2015 Dec 20.

Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan. Electronic address:

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January 2016

Middle-Down and Chemical Proteomic Approaches to Reveal Histone H4 Modification Dynamics in Cell Cycle: Label-Free Semi-Quantification of Histone Tail Peptide Modifications Including Phosphorylation and Highly Sensitive Capture of Histone PTM Binding Proteins Using Photo-Reactive Crosslinkers.

Mass Spectrom (Tokyo) 2015 14;4(1):A0039. Epub 2015 Jul 14.

Department of Systems Biology and Medicine, Research Center for Advanced Science and Technology, 
The University of Tokyo; The Translational Systems Biology and Medicine Initiative Center for Disease Biology and Integrative Medicine, 
Faculty of Medicine, University of Tokyo.

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January 2016

The feasibility of an efficient drug design method with high-performance computers.

Chem Pharm Bull (Tokyo) 2015 ;63(3):147-55

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo.

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December 2015

Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance.

Cell 2015 Nov;163(4):975-87

Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan; Takayanagi Osteonetwork Project, Exploratory Research for Advanced Technology Program, Japan Science and Technology Agency (JST), Tokyo 113-0033, Japan. Electronic address:

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November 2015

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation.

Mol Cell 2015 Nov;60(4):584-96

Division of Metabolic Medicine, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo 153-8904, Japan; The Translational Systems Biology and Medicine Initiative (TSBMI), Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan. Electronic address:

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November 2015

Lysophosphatidylcholine promotes SREBP-2 activation via rapid cholesterol efflux and SREBP-2-independent cytokine release in human endothelial cells.

J Biochem 2015 Oct 21;158(4):331-8. Epub 2015 May 21.

Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0321, Japan; and

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October 2015

An improvement on mass spectrometry-based epigenetic analysis of large histone-derived peptides by using the Ionization Variable Unit interface.

Anal Biochem 2015 Oct 5;486:14-6. Epub 2015 Jun 5.

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, University of Tokyo, Meguro-Ku, Tokyo 153-8904, Japan. Electronic address:

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October 2015

Analysis of the subcellular localization of the human histone methyltransferase SETDB1.

Biochem Biophys Res Commun 2015 Oct 18;465(4):725-31. Epub 2015 Aug 18.

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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October 2015

Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver.

J Atheroscler Thromb 2015 Aug 4;22(8):754-72. Epub 2015 Jun 4.

Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), University of Tokyo.

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August 2015

Crystal structure of streptavidin mutant with low immunogenicity.

J Biosci Bioeng 2015 Jun 26;119(6):642-7. Epub 2014 Nov 26.

Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan. Electronic address:

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June 2015

Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.

J Biochem 2015 Jun 2;157(6):467-75. Epub 2015 Feb 2.

Division of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan; and Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan

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June 2015

Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process.

Dev Biol 2015 Jun 16;402(2):162-74. Epub 2015 Apr 16.

Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Chiyoda-ku, Tokyo 102-0076, Japan; Institute for Biology and Mathematics of Dynamical Cell Processes (iBMath), The University of Tokyo, 3-8-1 Komaba, Tokyo 153-8914, Japan. Electronic address:

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June 2015

JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis.

Nat Commun 2015 May 7;6:7052. Epub 2015 May 7.

1] Division of Metabolic Medicine, Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, Tokyo 153-8904, Japan [2] The Translational Systems Biology and Medicine Initiative, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, University of Tokyo, Tokyo 113-8655, Japan.

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May 2015

Design and synthesis of biotin analogues reversibly binding with streptavidin.

Chem Asian J 2015 Apr 5;10(4):1071-8. Epub 2015 Mar 5.

Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan).

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April 2015

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.

Proc Natl Acad Sci U S A 2015 Mar 16;112(13):E1624-31. Epub 2015 Mar 16.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702

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March 2015

Molecular dynamics simulation-based evaluation of the binding free energies of computationally designed drug candidates: importance of the dynamical effects.

Chem Pharm Bull (Tokyo) 2014 ;62(7):661-7

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo.

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February 2015

Differential expression of pentraxin 3 in neutrophils.

Exp Mol Pathol 2015 Feb 20;98(1):33-40. Epub 2014 Nov 20.

Department of Cellular Function, Division of Cellular and Molecular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. Electronic address:

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February 2015

The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis.

J Biol Chem 2015 Feb 22;290(7):4163-77. Epub 2014 Dec 22.

From the Division of Metabolic Medicine, the Translational Systems Biology and Medicine Initiative Center for Disease Biology and Integrative Medicine, University of Tokyo, Tokyo 153-8904, Japan,

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February 2015

Clinical initiatives linking Japanese and Swedish healthcare resources on cancer studies utilizing Biobank Repositories.

Clin Transl Med 2014 Dec 22;3(1):61. Epub 2014 Nov 22.

First Department of Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku Shinjuku-ku, Tokyo, 160-0023 Japan ; Clinical Protein Science & Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, BMC D13, 221 84 Lund, Sweden ; Center of Excellence in Biological and Medical mass spectrometry (CEBMMS), 221 84 Lund, Sweden.

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December 2014

The orally available Btk inhibitor ibrutinib (PCI-32765) protects against osteoclast-mediated bone loss.

Bone 2014 Mar 4;60:8-15. Epub 2013 Dec 4.

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan; Department of Immunology, Graduate School of Medicine, The University of Tokyo, Japan; Japan Science and Technology Agency (JST), Explorative Research for Advanced Technology (ERATO) Program, Takayanagi Osteonetwork Project, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan. Electronic address:

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March 2014

Identification and characterization of the X-dimer of human P-cadherin: implications for homophilic cell adhesion.

Biochemistry 2014 Mar 10;53(11):1742-52. Epub 2014 Mar 10.

Department of Chemistry & Biotechnology, The University of Tokyo , Tokyo 108-8639, Japan.

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March 2014

In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B.

Virology 2014 Feb 18;450-451:13-23. Epub 2013 Dec 18.

Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address:

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February 2014

Revolution of nephrology research by deep sequencing: ChIP-seq and RNA-seq.

Kidney Int 2014 Jan 28;85(1):31-8. Epub 2013 Aug 28.

Division of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan.

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January 2014

Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

Nat Med 2014 Jan 22;20(1):62-8. Epub 2013 Dec 22.

1] Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. [2] Japan Science and Technology Agency (JST), Exploratory Research for Advanced Technology (ERATO) Program, Takayanagi Osteonetwork Project, Bunkyo-ku, Tokyo, Japan. [3] Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, Nedlands, Western Australia, Australia.

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January 2014

GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation.

Genes Cells 2013 Nov 1;18(11):921-33. Epub 2013 Aug 1.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan; Center for Radioisotope Sciences, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan; Department of Molecular Hematology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.

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November 2013

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle.

J Biol Chem 2013 Nov 7;288(46):33292-302. Epub 2013 Oct 7.

From the Department of Quantitative Biology and Medicine and.

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November 2013

Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.

Biochem Biophys Res Commun 2013 Nov 12;441(4):1011-7. Epub 2013 Nov 12.

Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.

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November 2013

Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication.

Nature 2013 Oct 8;502(7470):249-53. Epub 2013 Sep 8.

Department of Cell Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.

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October 2013

Different distribution of pentraxin 3 and C-reactive protein in coronary atherosclerotic plaques.

J Atheroscler Thromb 2012 11;19(9):837-45. Epub 2012 Jul 11.

Department of Internal Medicine, University of Miyazaki, Miyazaki, Japan.

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March 2013

Mutations for decreasing the immunogenicity and maintaining the function of core streptavidin.

Protein Sci 2013 Feb 4;22(2):213-21. Epub 2013 Jan 4.

Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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February 2013

Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways.

J Biol Chem 2013 Jan 27;288(2):1009-21. Epub 2012 Nov 27.

Department of Molecular Biology and Medicine, The University of Tokyo, Tokyo 153-8904, Japan.

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January 2013

Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.

J Biol Chem 2012 Nov 12;287(48):40256-65. Epub 2012 Oct 12.

Department of Cancer Biology, Division of Oncology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Tokyo 108-8639, Japan.

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November 2012

Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.

Hybridoma (Larchmt) 2012 Oct;31(5):325-32

Department of Molecular Biology and Medicine, The University of Tokyo, Meguro, Tokyo, Japan.

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October 2012

Pentraxin 3: a novel biomarker for inflammatory cardiovascular disease.

Int J Vasc Med 2012 4;2012:657025. Epub 2012 Jan 4.

Department of Cardiology, Juntendo University Nerima Hospital, Tokyo 177-0033, Japan.

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August 2012

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin.

Mol Biosyst 2012 Aug 7;8(8):2050-3. Epub 2012 Jun 7.

Department of Medical Genome Sciences, The University of Tokyo, Tokyo 108-8639, Japan.

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August 2012

Distribution of histone3 lysine 4 trimethylation at T3-responsive loci in the heart during reversible changes in gene expression.

Gene Expr 2012 ;15(4):183-98

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7525, USA.

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August 2012

Path-preference cellular-automaton model for traffic flow through transit points and its application to the transcription process in human cells.

Phys Rev E Stat Nonlin Soft Matter Phys 2012 Aug 21;86(2 Pt 1):021918. Epub 2012 Aug 21.

Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

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August 2012

The proteomic profile of circulating pentraxin 3 (PTX3) complex in sepsis demonstrates the interaction with azurocidin 1 and other components of neutrophil extracellular traps.

Mol Cell Proteomics 2012 Jun 25;11(6):M111.015073. Epub 2012 Jan 25.

Department of Molecular Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan.

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June 2012

Osteoprotection by semaphorin 3A.

Nature 2012 May;485(7396):69-74

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549, Japan.

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May 2012

Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis.

Proc Natl Acad Sci U S A 2011 Dec 5;108(51):20725-9. Epub 2011 Dec 5.

Department of Molecular Oncology, Graduate School of Medicine and Dentistry, Tokyo Medical and Dental University, 1-5-45 Bunkyo-ku, Yushima, Tokyo 113-8519, Japan.

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December 2011

Suppression of bone formation by osteoclastic expression of semaphorin 4D.

Nat Med 2011 Oct 23;17(11):1473-80. Epub 2011 Oct 23.

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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October 2011

Cellular-automaton model of the cooperative dynamics of RNA polymerase II during transcription in human cells.

Phys Rev E Stat Nonlin Soft Matter Phys 2011 Oct 19;84(4 Pt 1):041922. Epub 2011 Oct 19.

Research Center for Advanced Science and Technology, University of Tokyo, Tokyo 153-8904, Japan.

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October 2011

Associations of plasma pentraxin 3 and monocyte chemoattractant protein-1 concentrations with cardiovascular disease in patients with chronic kidney disease.

Ren Fail 2011 ;33(4):398-404

Division of Circulatory and Body Fluid Regulation, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

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September 2011

Evidence for osteocyte regulation of bone homeostasis through RANKL expression.

Nat Med 2011 Sep 11;17(10):1231-4. Epub 2011 Sep 11.

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan.

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September 2011

Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms.

Eur J Cell Biol 2011 Aug 21;90(8):657-64. Epub 2011 Apr 21.

Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.

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August 2011

The role of the BH3-only protein Noxa in bone homeostasis.

Biochem Biophys Res Commun 2011 Jul 13;410(3):620-5. Epub 2011 Jun 13.

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Tokyo 113-8549, Japan.

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July 2011

Genome-wide approaches reveal functional interleukin-4-inducible STAT6 binding to the vascular cell adhesion molecule 1 promoter.

Mol Cell Biol 2011 Jun 4;31(11):2196-209. Epub 2011 Apr 4.

Research Center for Advanced Science and Technology, University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8904, Japan.

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June 2011

A method of generating antibodies against exogenously administered self-antigen by manipulating CD4+CD25+ regulatory T cells.

J Immunol Methods 2011 Jun 3;369(1-2):108-14. Epub 2011 May 3.

Department of Molecular Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8904, Japan.

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June 2011

Long pentraxin 3 (PTX3) expression and release by neutrophils in vitro and in ulcerative colitis.

Pathol Int 2011 May 17;61(5):290-7. Epub 2011 Mar 17.

Department of Cellular Function, Division of Cellular and Molecular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Chuou-ku, Niigata, Japan.

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May 2011

The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma.

Histopathology 2011 Feb 23;58(3):467-76. Epub 2011 Feb 23.

Division of Cellular and Molecular Pathology, Niigata University Graduate School of Medical and Dental Sciences, Niigata University Hospital, Niigata, Japan.

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February 2011

Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation.

J Pharmacol Exp Ther 2010 Oct 13;335(1):32-41. Epub 2010 Jul 13.

Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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October 2010

Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals.

Neurosci Lett 2010 Oct 11;483(3):201-5. Epub 2010 Aug 11.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan.

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October 2010

Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation.

J Clin Invest 2010 Oct 27;120(10):3455-65. Epub 2010 Sep 27.

Department of Cell Signaling, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

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October 2010

Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.

FEBS Lett 2010 Jul 13;584(13):2909-15. Epub 2010 May 13.

Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.

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July 2010

Active RNA polymerases: mobile or immobile molecular machines?

PLoS Biol 2010 Jul 13;8(7):e1000419. Epub 2010 Jul 13.

Sir William Dunn School of Pathology, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.

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July 2010