Tatsuhiko Furukawa

Tatsuhiko Furukawa

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Tatsuhiko Furukawa

Publications by authors named "Tatsuhiko Furukawa"

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The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1.

Mol Carcinog 2019 02 2;58(2):234-246. Epub 2018 Nov 2.

Department of Medical Joint Materials, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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http://doi.wiley.com/10.1002/mc.22922
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http://dx.doi.org/10.1002/mc.22922DOI Listing
February 2019

Thymidine phosphorylase in cancer aggressiveness and chemoresistance.

Pharmacol Res 2018 06 28;132:15-20. Epub 2018 Mar 28.

Clinical Research Center, National Kyushu Cancer Center, 3-1-1 Notame Minami-ku, Fukuoka 811-1395, Japan.

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http://dx.doi.org/10.1016/j.phrs.2018.03.019DOI Listing
June 2018

A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of and analyses.

Oncoscience 2018 Mar 29;5(3-4):88-98. Epub 2018 Apr 29.

Department of Molecular Oncology, Graduate School Medical and Dental Sciences, Kagoshima University, Kagoshima 890- 8544, Japan.

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http://dx.doi.org/10.18632/oncoscience.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978436PMC
March 2018

ATP7B expression in human glioblastoma is related to temozolomide resistance.

Oncol Lett 2017 Dec 23;14(6):7777-7782. Epub 2017 Oct 23.

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.

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http://dx.doi.org/10.3892/ol.2017.7249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727628PMC
December 2017

Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity.

Comp Biochem Physiol C Toxicol Pharmacol 2017 Apr 3;194:22-27. Epub 2017 Feb 3.

Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, 890-0056 Kagoshima, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cbpc.2017.01.008DOI Listing
April 2017

Inhibition of casein kinase 2 prevents growth of human osteosarcoma.

Oncol Rep 2017 Feb 9;37(2):1141-1147. Epub 2016 Dec 9.

Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.3892/or.2016.5310DOI Listing
February 2017

Eel green fluorescent protein is associated with resistance to oxidative stress.

Comp Biochem Physiol C Toxicol Pharmacol 2016 Mar-Apr;181-182:35-9. Epub 2015 Dec 30.

Laboratory of Marine Biotechnology, Faculty of Fisheries, Kagoshima University, 4-50-20 Shimoarata, Kagoshima 890-0056, Japan.

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http://dx.doi.org/10.1016/j.cbpc.2015.12.009DOI Listing
October 2016

ATP7B expression confers multidrug resistance through drug sequestration.

Oncotarget 2016 Apr;7(16):22779-90

Department of Molecular Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan.

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http://dx.doi.org/10.18632/oncotarget.8059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008400PMC
April 2016

Combination of Hedgehog inhibitors and standard anticancer agents synergistically prevent osteosarcoma growth.

Int J Oncol 2016 Jan 6;48(1):235-42. Epub 2015 Nov 6.

Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.3892/ijo.2015.3236DOI Listing
January 2016

Okadaic acid is taken-up into the cells mediated by human hepatocytes transporter OATP1B3.

Food Chem Toxicol 2015 Sep 29;83:229-36. Epub 2015 Jun 29.

Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, Kagoshima 890-0056, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2015.06.006DOI Listing
September 2015

Naringin attenuates the cytotoxicity of hepatotoxin microcystin-LR by the curious mechanisms to OATP1B1- and OATP1B3-expressing cells.

Environ Toxicol Pharmacol 2015 Mar 7;39(2):974-81. Epub 2015 Mar 7.

Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, Kagoshima 890-0056, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.etap.2015.02.021DOI Listing
March 2015

Microcystin-LR induces anoikis resistance to the hepatocyte uptake transporter OATP1B3-expressing cell lines.

Toxicology 2014 Dec 16;326:53-61. Epub 2014 Oct 16.

Division of Food and Chemical Biology, Faculty of Fisheries, Kagoshima University, Kagoshima 890-0056, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2014.10.003DOI Listing
December 2014

Design and synthesis of prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitors as anti-prostate cancer drugs.

Bioorg Med Chem Lett 2014 Feb 11;24(4):1071-4. Epub 2014 Jan 11.

Advanced Medical Research Center, Hyogo University of Health Science, 1-3-6 Minatojima, Kobe 650-8530, Japan; Department of Pharmacy, Hyogo University of Health Science, 1-3-6 Minatojima, Kobe 650-8530, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.01.008DOI Listing
February 2014

Regulation of major vault protein expression by upstream stimulating factor 1 in SW620 human colon cancer cells.

Oncol Rep 2014 Jan 25;31(1):197-201. Epub 2013 Oct 25.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan.

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https://www.spandidos-publications.com/10.3892/or.2013.2818
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http://dx.doi.org/10.3892/or.2013.2818DOI Listing
January 2014

VEGF expression is augmented by hypoxia‑induced PGIS in human fibroblasts.

Int J Oncol 2013 Sep 27;43(3):746-54. Epub 2013 Jun 27.

Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.3892/ijo.2013.1994DOI Listing
September 2013

Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose.

Oncol Rep 2013 Sep 27;30(3):1444-8. Epub 2013 Jun 27.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-852, Japan.

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http://dx.doi.org/10.3892/or.2013.2572DOI Listing
September 2013

Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells.

Int J Mol Med 2013 Sep 2;32(3):703-8. Epub 2013 Jul 2.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.3892/ijmm.2013.1428DOI Listing
September 2013

Influence of gefitinib and erlotinib on apoptosis and c-MYC expression in H23 lung cancer cells.

Anticancer Res 2013 Apr;33(4):1547-54

Department of Cardiovascular, Respiratory and Metabolic Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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April 2013

Snail modulates cell metabolism in MDCK cells.

Biochem Biophys Res Commun 2013 Mar 21;432(4):618-25. Epub 2013 Feb 21.

Department of Biochemistry and Molecular Biology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2013.02.035DOI Listing
March 2013

Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells.

Oncol Rep 2012 Sep 26;28(3):895-902. Epub 2012 Jun 26.

Department of Medical Oncology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.3892/or.2012.1887DOI Listing
September 2012

Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3.

Biochim Biophys Acta 2012 Aug 2;1823(8):1316-23. Epub 2012 Jun 2.

Department of Molecular Cardiology, The Cleveland Clinic, OH, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2012.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133185PMC
August 2012

CD147-targeting siRNA inhibits cell-matrix adhesion of human malignant melanoma cells by phosphorylating focal adhesion kinase.

J Dermatol 2012 Jan 3;39(1):63-7. Epub 2011 Oct 3.

Department of Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

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http://doi.wiley.com/10.1111/j.1346-8138.2011.01304.x
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http://dx.doi.org/10.1111/j.1346-8138.2011.01304.xDOI Listing
January 2012

Novel cytotoxic isolated from Jamaican Hyptis verticillata jacq induces apoptosis and overcomes multidrug resistance.

Anticancer Res 2011 Dec;31(12):4251-7

Division of Hematology and Immunology, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8544, Japan.

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December 2011

p53 Plays an important role in cell fate determination after exposure to microcystin-LR.

Environ Health Perspect 2010 Sep 26;118(9):1292-8. Epub 2010 Apr 26.

Department of Environmental Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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https://ehp.niehs.nih.gov/doi/10.1289/ehp.1001899
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http://dx.doi.org/10.1289/ehp.1001899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944092PMC
September 2010

Cytotoxic isomalabaricane derivatives and a monocyclic triterpene glycoside from the sponge Rhabdastrella globostellata.

J Nat Prod 2010 Sep;73(9):1512-8

Department of Chemistry and Bioscience, Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima 890-0065, Japan.

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http://dx.doi.org/10.1021/np100302aDOI Listing
September 2010

Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1alpha and reduces HIF-1alpha level in ACHN human renal adenocarcinoma cells.

Cancer Sci 2010 Apr 18;101(4):920-6. Epub 2010 Feb 18.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01481.xDOI Listing
April 2010

Copper transport systems are involved in multidrug resistance and drug transport.

Curr Med Chem 2008 ;15(30):3268-78

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan.

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March 2009

Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance.

Biochem Pharmacol 2009 Mar 25;77(6):993-1001. Epub 2008 Dec 25.

Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, NY, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520800889
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http://dx.doi.org/10.1016/j.bcp.2008.12.005DOI Listing
March 2009

Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in human colon cancer KM12C cells.

Cancer Lett 2008 Oct 25;270(1):156-63. Epub 2008 Jun 25.

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima, Japan.

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http://dx.doi.org/10.1016/j.canlet.2008.04.045DOI Listing
October 2008

Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.

Exp Cell Res 2008 Oct 9;314(16):3017-26. Epub 2008 Jul 9.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.yexcr.2008.07.001DOI Listing
October 2008

Subcellular distribution and potential detoxification mechanisms of mercury in the liver of the Javan mongoose (Herpestes javanicus) in Amamioshima Island, Japan.

Environ Toxicol Chem 2008 Jun 16;27(6):1354-60. Epub 2008 Jan 16.

Department of Molecular Oncology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

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http://entc.allenpress.com/perlserv/?request=get-abstract&am
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http://dx.doi.org/10.1897/07-370DOI Listing
June 2008

Thymidine phosphorylase inhibits the expression of proapoptotic protein BNIP3.

Biochem Biophys Res Commun 2008 May 24;370(2):220-4. Epub 2008 Mar 24.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.067DOI Listing
May 2008

Isolation and characterization of arsenite-resistant human epidermoid carcinoma KB cells.

Oncol Rep 2007 Sep;18(3):721-7

Department of Molecular Oncology, Course of Advanced Therapeutics, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.

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September 2007

Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.

Cancer Lett 2006 Dec 7;244(2):239-46. Epub 2006 Feb 7.

Department of Molecular Oncology, Field of Oncology, Course of Advanced Therapeutics, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.canlet.2005.12.020DOI Listing
December 2006

2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.

Int J Cancer 2006 Oct;119(7):1710-6

Department of Molecular Oncology, Field of Oncology, Course of Advanced Therapeutics,Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, Japan.

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http://dx.doi.org/10.1002/ijc.22014DOI Listing
October 2006

A functional role of intracellular loops of human multidrug resistance protein 1.

J Biochem 2006 Sep 21;140(3):313-8. Epub 2006 Jul 21.

Department of Molecular Oncology and Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520.

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http://dx.doi.org/10.1093/jb/mvj155DOI Listing
September 2006

The small heat shock protein alphaB-crystallin inhibits differentiation-induced caspase 3 activation and myogenic differentiation.

Biol Pharm Bull 2006 Sep;29(9):1815-9

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Sakuragaoka, Kagoshima, Japan.

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http://dx.doi.org/10.1248/bpb.29.1815DOI Listing
September 2006

Overexpression of survivin in primary ATL cells and sodium arsenite induces apoptosis by down-regulating survivin expression in ATL cell lines.

Blood 2006 Jun 23;107(12):4880-7. Epub 2006 Feb 23.

Department of Molecular Oncology, Graduate School of Medical & Dental Sciences, Kagoshima University, Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1182/blood-2005-08-3423DOI Listing
June 2006

Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.

Int J Mol Med 2006 Jun;17(6):1085-91

Department of Urology, Field of Oncology, Course of Advanced Therapeutics, Kagoshima University Graduate School of Medical and Dental Sciences, Japan.

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June 2006

Direct activation of the human major vault protein gene by DNA-damaging agents.

Oncol Rep 2006 Mar;15(3):645-52

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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March 2006

2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.

Biochem Biophys Res Commun 2006 Mar 6;342(1):280-5. Epub 2006 Feb 6.

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.01.142DOI Listing
March 2006

Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase.

FEBS Lett 2006 Feb 26;580(5):1294-302. Epub 2006 Jan 26.

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1, Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.febslet.2006.01.047DOI Listing
February 2006

[Mechanisms of substrate transport by ABC transporter, MRP1/ABCC1].

Seikagaku 2006 Feb;78(2):110-21

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Japan.

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February 2006

Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents.

Biochem Pharmacol 2005 Jul;70(1):13-21

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1, Sakuragaoka, Kagoshima, 890-8520, Japan.

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http://dx.doi.org/10.1016/j.bcp.2005.04.017DOI Listing
July 2005

Multidrug resistance-associated protein MRP-1 regulates dauer diapause by its export activity in Caenorhabditis elegans.

Development 2005 Jul;132(14):3197-207

Structural Biology Center, National Institute of Genetics, and Department of Genetics, The Graduate University for Advanced Studies, Mishima 411-8540, Japan.

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http://dev.biologists.org/cgi/doi/10.1242/dev.01909
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http://dx.doi.org/10.1242/dev.01909DOI Listing
July 2005

Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells.

Cancer Sci 2005 Jun;96(6):372-6

Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2005.00057.xDOI Listing
June 2005

GSH inhibits trypsinization of the C-terminal half of human MRP1.

J Biol Chem 2005 Feb 3;280(7):6231-7. Epub 2004 Dec 3.

Department of Molecular Oncology, Field of Oncology, Course of Advanced Therapeutics, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1074/jbc.M409498200DOI Listing
February 2005

Characterization of MVP and VPARP assembly into vault ribonucleoprotein complexes.

Biochem Biophys Res Commun 2005 Jan;326(1):100-7

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.11.006DOI Listing
January 2005

The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.

Cancer Sci 2004 Nov;95(11):851-7

Department of Molecular Oncology, Course of Advanced Therapeutics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544.

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http://dx.doi.org/10.1111/j.1349-7006.2004.tb02193.xDOI Listing
November 2004

Induction of cellular resistance to nucleoside reverse transcriptase inhibitors by the wild-type breast cancer resistance protein.

Biochem Pharmacol 2004 Oct;68(7):1363-70

Division of Antiviral Chemotherapy, Center for Chronic Viral Diseases, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.

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http://dx.doi.org/10.1016/j.bcp.2004.05.052DOI Listing
October 2004

Function of the ABC signature sequences in the human multidrug resistance protein 1.

Mol Pharmacol 2004 Jun;65(6):1536-42

Department of Molecular Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

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http://dx.doi.org/10.1124/mol.65.6.1536DOI Listing
June 2004

Binding site(s) on P-glycoprotein for a newly synthesized photoaffinity analog of agosterol A.

Oncol Res 2003 ;14(1):39-48

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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May 2004

Inhibition of metastasis of tumor cells overexpressing thymidine phosphorylase by 2-deoxy-L-ribose.

Cancer Res 2004 Mar;64(5):1794-801

Department of Molecular Oncology, Graduate School of Medical and Dental Science, Kagoshima University, Kagoshima Japan.

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March 2004

[Thymidine phosphorylase inhibits apoptosis induced by anticancer agents].

Nihon Yakurigaku Zasshi 2003 Nov;122 Suppl:84P-86P

Department of Clinical Pharmacy and Pharmacology, Department of Cancer Chemotherapy, Institute for Cancer Research, Graduate School of Medical and Dental Sciences, Kagoshima University 890-8520, Sakuragaoka 8-35-1, Japan.

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November 2003

Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells.

Cancer Sci 2003 Jun;94(6):557-63

Department of Cancer Chemotherapy, Institute for Cancer Research, Kagoshima University, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2003.tb01482.xDOI Listing
June 2003

Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.

Br J Pharmacol 2003 Apr;138(8):1553-61

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1038/sj.bjp.0705197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573804PMC
April 2003

Thymidine phosphorylase inhibits apoptosis induced by cisplatin.

Biochem Biophys Res Commun 2003 Feb;301(2):358-63

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890, Japan.

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http://dx.doi.org/10.1016/s0006-291x(02)03034-6DOI Listing
February 2003

Enhanced nucleotide excision repair in cisplatin resistant human KB carcinoma cells.

Oncol Rep 2002 Jul-Aug;9(4):839-44

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.

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January 2003

Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.

Mol Pharmacol 2003 Jan;63(1):65-72

Division of Human Retroviruses, Center for Chronic Viral Diseases, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.

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http://dx.doi.org/10.1124/mol.63.1.65DOI Listing
January 2003

Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519.

Cancer Lett 2002 Dec;187(1-2):111-9

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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December 2002

A positively charged amino acid proximal to the C-terminus of TM17 of MRP1 is indispensable for GSH-dependent binding of substrates and for transport of LTC4.

Biochemistry 2002 Dec;41(48):14132-40

Department of Cancer Chemotherapy, Institute for Cancer Research, Faculty of Medicine, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1021/bi026443sDOI Listing
December 2002

Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.

Mol Cancer Res 2002 Dec;1(2):155-63

Department of Immunology, Graduate School of Pharmaceutical Sciences, Osaka University, Yamadaoka, Suita, Osaka, Japan.

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December 2002

Lembehsterols A and B, novel sulfated sterols inhibiting thymidine phosphorylase, from the marine sponge Petrosia strongylata.

Chem Pharm Bull (Tokyo) 2002 Jun;50(6):827-30

Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1248/cpb.50.827DOI Listing
June 2002

Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

Cancer Res 2002 May;62(10):2834-9

Department of Cancer Chemotherapy, Institute for Cancer Research, Kagoshima University, Faculty of Medicine, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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May 2002

Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.

Biochem Biophys Res Commun 2002 Mar;291(4):806-12

Department of Cancer Chemotherapy, Institute for Cancer Research, Kagoshima University, Sakuragaoka 8-35-1, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1006/bbrc.2002.6432DOI Listing
March 2002