Taroh Kinoshita

Taroh Kinoshita

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Lipid moiety of glycosylphosphatidylinositol-anchored proteins contributes to the determination of their final destination in yeast.

Genes Cells 2018 Oct 1;23(10):880-892. Epub 2018 Oct 1.

Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan.

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http://dx.doi.org/10.1111/gtc.12636DOI Listing
October 2018

Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in .

J Cell Sci 2018 10 26;131(20). Epub 2018 Oct 26.

Department of Life Science, Rikkyo University, Toshima-ku, Tokyo 171-8501, Japan

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http://dx.doi.org/10.1242/jcs.218024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215393PMC
October 2018

Recurrent aseptic meningitis with mutations: a novel pathogenesis of recurrent meningitis successfully treated by eculizumab.

BMJ Case Rep 2018 Sep 27;2018. Epub 2018 Sep 27.

Department of Neurology, Kobe City Medical Center General Hospital, Kobe, Japan.

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http://dx.doi.org/10.1136/bcr-2018-225910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169622PMC
September 2018

Congenital Defects in the Expression of the Glycosylphosphatidylinositol-Anchored Complement Regulatory Proteins CD59 and Decay-Accelerating Factor.

Authors:
Taroh Kinoshita

Semin Hematol 2018 07 16;55(3):136-140. Epub 2018 Apr 16.

Yabumoto Department of Intractable Disease Research, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2018.04.004DOI Listing
July 2018

A homozygous variant disrupting the PIGH start-codon is associated with developmental delay, epilepsy, and microcephaly.

Hum Mutat 2018 06 30;39(6):822-826. Epub 2018 Mar 30.

National Institute for Health Research Oxford Biomedical Research Centre, Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, UK.

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http://dx.doi.org/10.1002/humu.23420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001798PMC
June 2018

-Glycan-dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing.

J Cell Biol 2018 02 18;217(2):585-599. Epub 2017 Dec 18.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Jiangsu, China

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http://www.jcb.org/lookup/doi/10.1083/jcb.201706135
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http://dx.doi.org/10.1083/jcb.201706135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800811PMC
February 2018

Early infancy-onset stimulation-induced myoclonic seizures in three siblings with inherited glycosylphosphatidylinositol (GPI) anchor deficiency.

Epileptic Disord 2018 Feb;20(1):42-50

Department of Immunoregulation, Research Institute for Microbial Diseases, Osaka University, Osaka.

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http://dx.doi.org/10.1684/epd.2018.0956DOI Listing
February 2018

Epileptic apnea in a patient with inherited glycosylphosphatidylinositol anchor deficiency and PIGT mutations.

Brain Dev 2018 Jan 17;40(1):53-57. Epub 2017 Jul 17.

Department of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.braindev.2017.06.005DOI Listing
January 2018

Molecular genetics, biochemistry, and biology of PNH.

Authors:
Taroh Kinoshita

Rinsho Ketsueki 2017 ;58(4):353-362

Research Institute for Microbial Diseases, Osaka University.

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http://dx.doi.org/10.11406/rinketsu.58.353DOI Listing
November 2017

Paroxysmal nocturnal haemoglobinuria.

Nat Rev Dis Primers 2017 05 18;3:17028. Epub 2017 May 18.

Division of Hematology, Johns Hopkins Department of Medicine, Johns Hopkins University, Ross Research Building, Room 1025, 720 Rutland Avenue, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/nrdp.2017.28DOI Listing
May 2017

Crystallographic analysis of murine p24γ2 Golgi dynamics domain.

Proteins 2017 04 23;85(4):764-770. Epub 2017 Jan 23.

Structural Glycobiology Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, RIKEN Global Research Cluster, 2-1 Hirosawa, Wako-City, Saitama, 351-0198, Japan.

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http://dx.doi.org/10.1002/prot.25242DOI Listing
April 2017

Mutations in the phosphatidylinositol glycan C () gene are associated with epilepsy and intellectual disability.

J Med Genet 2017 03 30;54(3):196-201. Epub 2016 Sep 30.

Monique and Jacques Roboh Department of Genetic Research, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1136/jmedgenet-2016-104202DOI Listing
March 2017

PIGN prevents protein aggregation in the endoplasmic reticulum independently of its function in the GPI synthesis.

J Cell Sci 2017 02 15;130(3):602-613. Epub 2016 Dec 15.

Multicellular Organization Laboratory, National Institute of Genetics, Mishima 411-8540, Japan.

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http://dx.doi.org/10.1242/jcs.196717DOI Listing
February 2017

Glycan region of GPI anchored-protein is required for cytocidal oligomerization of an anticancer parasporin-2, Cry46Aa1 protein, from Bacillus thuringiensis strain A1547.

J Invertebr Pathol 2017 01 15;142:71-81. Epub 2016 Nov 15.

Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka 812-8581, Japan; Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka 820-8502, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jip.2016.11.008DOI Listing
January 2017

A homozygous PIGN missense mutation in Soft-Coated Wheaten Terriers with a canine paroxysmal dyskinesia.

Neurogenetics 2017 01 28;18(1):39-47. Epub 2016 Nov 28.

Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, 65211, USA.

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http://link.springer.com/10.1007/s10048-016-0502-4
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http://dx.doi.org/10.1007/s10048-016-0502-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243907PMC
January 2017

A novel mutation in PIGW causes glycosylphosphatidylinositol deficiency without hyperphosphatasia.

Am J Med Genet A 2016 12 14;170(12):3319-3322. Epub 2016 Sep 14.

Universitätsklinikum Münster, Klinik für Kinder- und Jugendmedizin, Albert-Schweitzer-Campus 1, Münster, Germany.

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http://dx.doi.org/10.1002/ajmg.a.37950DOI Listing
December 2016

3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport.

J Mol Biol 2016 10 25;428(20):4087-4099. Epub 2016 Aug 25.

Structural Glycobiology Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, RIKEN Global Research Cluster, 2-1 Hirosawa, Wako City, Saitama 351-0198, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2016.08.023DOI Listing
October 2016

Lipoarabinomannan binding to lactosylceramide in lipid rafts is essential for the phagocytosis of mycobacteria by human neutrophils.

Sci Signal 2016 10 11;9(449):ra101. Epub 2016 Oct 11.

Laboratory of Biochemistry, Juntendo University Faculty of Health Care and Nursing, Urayasu, Chiba 279-0023, Japan. Institute for Environmental and Gender-Specific Medicine, Juntendo University Graduate School of Medicine, Urayasu, Chiba 279-0021, Japan. Infection Control Nursing, Juntendo University Graduate School of Health Care and Nursing, Urayasu, Chiba 279-0023, Japan.

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http://dx.doi.org/10.1126/scisignal.aaf1585DOI Listing
October 2016

Genome-Wide Screening of Genes Required for Glycosylphosphatidylinositol Biosynthesis.

PLoS One 2015 18;10(9):e0138553. Epub 2015 Sep 18.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, 214122, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575048PMC
May 2016

Pathogenic Variants in PIGG Cause Intellectual Disability with Seizures and Hypotonia.

Am J Hum Genet 2016 Apr 17;98(4):615-26. Epub 2016 Mar 17.

Department of Immunoregulation, Research Institute for Microbial Diseases, and World Premier International Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833197PMC
April 2016

Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling.

J Lipid Res 2016 Jan 12;57(1):6-24. Epub 2015 Nov 12.

Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.

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http://dx.doi.org/10.1194/jlr.R063313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689344PMC
January 2016

Glycosylphosphatidylinositol (GPI) Anchors: Biochemistry and Cell Biology: Introduction to a Thematic Review Series.

Authors:
Taroh Kinoshita

J Lipid Res 2016 Jan 18;57(1):4-5. Epub 2015 Nov 18.

WPI Immunology Frontier Research Center and Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan

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http://dx.doi.org/10.1194/jlr.E065417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689333PMC
January 2016

Cerebral visual impairment and intellectual disability caused by PGAP1 variants.

Eur J Hum Genet 2015 Dec 25;23(12):1689-93. Epub 2015 Mar 25.

Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ejhg.2015.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795198PMC
December 2015

Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.

Mol Biol Cell 2015 Sep 8;26(17):3071-84. Epub 2015 Jul 8.

Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan

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http://dx.doi.org/10.1091/mbc.E14-11-1568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551320PMC
September 2015

[Inherited GPI deficiency; a new disease with intellectual disability and epilepsy].

Nihon Rinsho 2015 Jul;73(7):1227-37

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July 2015

Structural changes of GPI anchor after its attachment to proteins: functional significance.

Authors:
Taroh Kinoshita

Adv Exp Med Biol 2015 ;842:17-25

WPI Immunology Frontier Research Center and Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka, 565-0871, Japan,

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http://link.springer.com/10.1007/978-3-319-11280-0_2
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http://dx.doi.org/10.1007/978-3-319-11280-0_2DOI Listing
May 2015

Mutations in PIGL in a patient with Mabry syndrome.

Am J Med Genet A 2015 Apr 23;167A(4):777-85. Epub 2015 Feb 23.

Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1002/ajmg.a.36987DOI Listing
April 2015

Enzymatic mechanism of GPI anchor attachment clarified.

Authors:
Taroh Kinoshita

Cell Cycle 2014 27;13(12):1838-9. Epub 2014 May 27.

WPI Immunology Frontier Research Center and Research Institute for Microbial Diseases; Osaka University; Osaka, Japan.

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http://dx.doi.org/10.4161/cc.29379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111747PMC
January 2015

[Inherited GPI deficiencies:a new disease with intellectual disability and epilepsy].

No To Hattatsu 2015 Jan;47(1):5-13

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January 2015

Paroxysmal nocturnal hemoglobinuria with copy number-neutral 6pLOH in GPI (+) but not in GPI (-) granulocytes.

Eur J Haematol 2014 30;92(5):450-3. Epub 2014 Jan 30.

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/ejh.12253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060154PMC
December 2014

Biosynthesis and deficiencies of glycosylphosphatidylinositol.

Authors:
Taroh Kinoshita

Proc Jpn Acad Ser B Phys Biol Sci 2014 ;90(4):130-43

WPI Immunology Frontier Research Center and Research Institute for Microbial Diseases, Osaka University.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055706PMC
http://dx.doi.org/10.2183/pjab.90.130DOI Listing
November 2014

Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.

BMC Genomics 2014 Nov 24;15:1016. Epub 2014 Nov 24.

Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1186/1471-2164-15-1016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301880PMC
November 2014

New insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesis.

Biochem J 2014 Oct;463(2):249-56

*Laboratory of Immunoglycobiology, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://biochemj.org/lookup/doi/10.1042/BJ20140541
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http://dx.doi.org/10.1042/BJ20140541DOI Listing
October 2014

[Biochemistry of glycosylphosphatidylinositol (GPI) anchored proteins].

Authors:
Taroh Kinoshita

Seikagaku 2014 Oct;86(5):626-36

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October 2014

Novel compound heterozygous PIGT mutations caused multiple congenital anomalies-hypotonia-seizures syndrome 3.

Neurogenetics 2014 Aug 8;15(3):193-200. Epub 2014 Jun 8.

Department of Human Genetics, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.

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http://link.springer.com/content/pdf/10.1007/s10048-014-0408
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http://link.springer.com/10.1007/s10048-014-0408-y
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http://dx.doi.org/10.1007/s10048-014-0408-yDOI Listing
August 2014

The α-helical region in p24γ2 subunit of p24 protein cargo receptor is pivotal for the recognition and transport of glycosylphosphatidylinositol-anchored proteins.

J Biol Chem 2014 Jun 28;289(24):16835-43. Epub 2014 Apr 28.

From the World Premier International (WPI) Immunology Frontier Research Center and Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan and

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http://dx.doi.org/10.1074/jbc.M114.568311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059126PMC
June 2014

PIGA mutations cause early-onset epileptic encephalopathies and distinctive features.

Neurology 2014 May 4;82(18):1587-96. Epub 2014 Apr 4.

From the Department of Pediatrics (M.K., K.H.), Yamagata University Faculty of Medicine, Yamagata; Department of Human Genetics (H.S., C.O., M.N., Y.T., N. Miyake, N. Matsumoto), Yokohama City University Graduate School of Medicine, Yokohama; Department of Immunoregulation (Y.M., T.K.), Research Institute for Microbial Diseases, and WPI Immunology Frontier Research Center, Osaka University, Suita; Division of Neurology (K.K., R.M., S.-i.H.), Saitama Children's Medical Center, Saitama; Division of Neurology (S.W.), Miyagi Children's Hospital, Sendai; Division of Neurology (M.I., H.O.), Clinical Research Institute, Kanagawa Children's Medical Center, Yokohama; Department of Pediatrics (K.M.), Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama; Department of Pediatrics (R.T.), Aomori Prefectural Central Hospital, Aomori; and Department of Pediatrics (H.O.), Jichi Medical School, Tochigi, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000000389DOI Listing
May 2014

Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation.

Am J Hum Genet 2014 Feb 16;94(2):278-87. Epub 2014 Jan 16.

Institute for Medical Genetics and Human Genetics, Charité Universitätsmedizin, 13353 Berlin, Germany; Berlin Brandenburg Center for Regenerative Therapies, Charité Universitätsmedizin, 13353 Berlin, Germany; Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(13)00582-X.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971300582
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http://dx.doi.org/10.1016/j.ajhg.2013.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928656PMC
February 2014

Genetic variants in C5 and poor response to eculizumab.

N Engl J Med 2014 Feb;370(7):632-9

From Osaka University Graduate School of Medicine (J.N., M.Y., H.S., Y.K.) and World Premier International Immunology Frontier Research Center and Research Institute for Microbial Diseases, Osaka University, Suita (T.K.), Medical Research Institute and Hard Tissue Genome Research Center, Tokyo Medical and Dental University (S.H., J.I.), Tokyo Medical University (K.O.), and Alexion Pharma (M.H.), Tokyo, Tokai University School of Medicine, Isehara (K.A.), Fukushima Medical University, Fukushima (H.N., T.S.), Ichinomiya Municipal Hospital, Ichinomiya (K.K.), Hamanomachi Hospital, Fukuoka (T.E.), Yamaguchi Grand Medical Center, Hofu (T.T.), Niigata University Medical and Dental Hospital, Niigata (M.M.), Japanese Red Cross Takayama Hospital, Takayama (T.M.), and Iwate Prefectual Central Hospital, Morioka (Y.W.) - all in Japan; University of Buenos Aires, Buenos Aires (A.L.B., A.L.); and Alexion Pharmaceuticals, Cheshire, CT (L.L., K.J., P.T.).

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http://dx.doi.org/10.1056/NEJMoa1311084DOI Listing
February 2014

Transport of glycosylphosphatidylinositol-anchored proteins from the endoplasmic reticulum.

Biochim Biophys Acta 2013 Nov 1;1833(11):2473-8. Epub 2013 Feb 1.

Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.bbamcr.2013.01.027DOI Listing
November 2013

Vitamin B6-responsive epilepsy due to inherited GPI deficiency.

Neurology 2013 Oct 18;81(16):1467-9. Epub 2013 Sep 18.

From Osaka City General Hospital (I.K., S.O., H.K., E.E.); National Epilepsy Center (Y.T.), Shizuoka Institute of Epilepsy and Neurological Disorders, Urushiyama, Shizuoka; Department of Molecular Genetics (N.I.), Osaka Medical Center for Cancer; and Research Institute for Microbial Diseases (T.K., Y.M.), Department of Immunoglycobiology, WPI Immunology Frontier Research Center, Osaka University, Japan.

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http://dx.doi.org/10.1212/WNL.0b013e3182a8411aDOI Listing
October 2013

Glycosylphosphatidylinositol mannosyltransferase II is the rate-limiting enzyme in glycosylphosphatidylinositol biosynthesis under limited dolichol-phosphate mannose availability.

J Biochem 2013 Sep 20;154(3):257-64. Epub 2013 May 20.

Research Institute for Microbial Diseases and WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1093/jb/mvt045DOI Listing
September 2013

Significance of glycosylphosphatidylinositol-anchored protein enrichment in lipid rafts for the control of autoimmunity.

J Biol Chem 2013 Aug 17;288(35):25490-9. Epub 2013 Jul 17.

Department of Immunoregulation, Research Institute for Microbial Diseases, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1074/jbc.M113.492611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757210PMC
August 2013

Implications of lipid moiety in oligomerization and immunoreactivities of GPI-anchored proteins.

J Lipid Res 2013 Apr 3;54(4):1077-91. Epub 2013 Feb 3.

Department of Immunoregulation, Research Institute for Microbial Diseases, and Laboratory of Immunoglycobiology, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1194/jlr.M034421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605984PMC
April 2013

GPI-anchor remodeling: potential functions of GPI-anchors in intracellular trafficking and membrane dynamics.

Biochim Biophys Acta 2012 Aug 11;1821(8):1050-8. Epub 2012 Jan 11.

Research Institute for Microbial Diseases and WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.bbalip.2012.01.004DOI Listing
August 2012

Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels.

J Lipid Res 2012 Aug 24;53(8):1522-34. Epub 2012 May 24.

Department of Biochemistry, NCCR Chemical Biology, University of Geneva, CH-1211 Geneva, Switzerland.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M025692
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http://dx.doi.org/10.1194/jlr.M025692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540855PMC
August 2012

Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria.

Br J Haematol 2012 Feb 24;156(3):383-7. Epub 2011 Oct 24.

Department of Immunoregulation, Research Institute for Microbial Diseases Department of Immunoglycobiology, WPI Immunology Frontier Research Centre, Osaka, Japan.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08914.xDOI Listing
February 2012

Mechanism for release of alkaline phosphatase caused by glycosylphosphatidylinositol deficiency in patients with hyperphosphatasia mental retardation syndrome.

J Biol Chem 2012 Feb 6;287(9):6318-25. Epub 2012 Jan 6.

Department of Immunoregulation, Research Institute for Microbial Diseases, and Laboratory of Immunoglycobiology, WPI Immunology Frontier Research Center, Osaka, Japan 565-0871, Japan.

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http://www.jbc.org/content/287/9/6318.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M111.331090
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http://dx.doi.org/10.1074/jbc.M111.331090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307314PMC
February 2012

Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins.

Biochem Biophys Res Commun 2012 Jan 29;417(4):1235-41. Epub 2011 Dec 29.

Department of Immunoregulation, Research Institute for Microbial Diseases, Laboratory of Immunoglycobiology, WPI Immunology Frontier Research Center, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1102325
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http://dx.doi.org/10.1016/j.bbrc.2011.12.116DOI Listing
January 2012

Identification of a second catalytically active trans-sialidase in Trypanosoma brucei.

Biochem Biophys Res Commun 2011 Nov 21;415(2):421-5. Epub 2011 Oct 21.

Department of Immunoregulation, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.10.085DOI Listing
November 2011

Structural remodeling, trafficking and functions of glycosylphosphatidylinositol-anchored proteins.

Prog Lipid Res 2011 Oct 30;50(4):411-24. Epub 2011 May 30.

Department of Immunoregulation, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/j.plipres.2011.05.002DOI Listing
October 2011

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI.

J Cell Biol 2011 Jul 4;194(1):61-75. Epub 2011 Jul 4.

Research Institute for Microbial Diseases and WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1083/jcb.201012074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135397PMC
July 2011

Inositol lipid metabolism in mycobacteria: biosynthesis and regulatory mechanisms.

Biochim Biophys Acta 2011 Jun 5;1810(6):630-41. Epub 2011 Apr 5.

Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.bbagen.2011.03.017DOI Listing
June 2011