Tarja Laitinen

Tarja Laitinen

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Tarja Laitinen

Publications by authors named "Tarja Laitinen"

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Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients.

Sleep Breath 2019 Dec 8;23(4):1209-1217. Epub 2019 Mar 8.

Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital and University of Turku, Hämeentie 11, FI-20520, Turku, Finland.

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http://dx.doi.org/10.1007/s11325-019-01808-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868046PMC
December 2019

Retrospective Evaluation of Lung Adenocarcinoma Patients Progressing on 1st Line Chemotherapy.

Medicina (Kaunas) 2019 Nov 16;55(11). Epub 2019 Nov 16.

Boehringer Ingelheim Finland Ky, 00180 Helsinki, Finland.

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http://dx.doi.org/10.3390/medicina55110743DOI Listing
November 2019

Consistency and reliability of smoking-related variables: longitudinal study design in asthma and COPD.

Eur Clin Respir J 2019 11;6(1):1591842. Epub 2019 Apr 11.

Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.1080/20018525.2019.1591842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461091PMC
April 2019

Response to letter entitled "CPAP adherence and cardiovascular disease: beware of the healthy adherer effect".

Sleep Breath 2019 Apr 27. Epub 2019 Apr 27.

Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital and University of Turku, Hämeentie 11, FIN-20520, Turku, Finland.

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http://dx.doi.org/10.1007/s11325-019-01850-2DOI Listing
April 2019

Predictors of New Airway Obstruction - An 11 Year's Population-Based Follow-Up Study.

COPD 2019 02 1;16(1):45-50. Epub 2019 Mar 1.

a University of Turku, Division of Medicine, Department of Pulmonary Diseases and Clinical Allergology , Turku University Hospital and University of Turku , Turku , Finland.

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http://dx.doi.org/10.1080/15412555.2019.1576163DOI Listing
February 2019

Estimating the effectiveness of pulmonary rehabilitation for COPD exacerbations: reduction of hospital inpatient days during the following year.

Int J Chron Obstruct Pulmon Dis 2017 22;12:2763-2769. Epub 2017 Sep 22.

Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital, University of Turku, Turku, Finland.

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http://dx.doi.org/10.2147/COPD.S144571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624742PMC
June 2018

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Authors:
Florence Demenais Patricia Margaritte-Jeannin Kathleen C Barnes William O C Cookson Janine Altmüller Wei Ang R Graham Barr Terri H Beaty Allan B Becker John Beilby Hans Bisgaard Unnur Steina Bjornsdottir Eugene Bleecker Klaus Bønnelykke Dorret I Boomsma Emmanuelle Bouzigon Christopher E Brightling Myriam Brossard Guy G Brusselle Esteban Burchard Kristin M Burkart Andrew Bush Moira Chan-Yeung Kian Fan Chung Alexessander Couto Alves John A Curtin Adnan Custovic Denise Daley Johan C de Jongste Blanca E Del-Rio-Navarro Kathleen M Donohue Liesbeth Duijts Celeste Eng Johan G Eriksson Martin Farrall Yuliya Fedorova Bjarke Feenstra Manuel A Ferreira Maxim B Freidin Zofia Gajdos Jim Gauderman Ulrike Gehring Frank Geller Jon Genuneit Sina A Gharib Frank Gilliland Raquel Granell Penelope E Graves Daniel F Gudbjartsson Tari Haahtela Susan R Heckbert Dick Heederik Joachim Heinrich Markku Heliövaara John Henderson Blanca E Himes Hiroshi Hirose Joel N Hirschhorn Albert Hofman Patrick Holt Jouke Hottenga Thomas J Hudson Jennie Hui Medea Imboden Vladimir Ivanov Vincent W V Jaddoe Alan James Christer Janson Marjo-Riitta Jarvelin Deborah Jarvis Graham Jones Ingileif Jonsdottir Pekka Jousilahti Michael Kabesch Mika Kähönen David B Kantor Alexandra S Karunas Elza Khusnutdinova Gerard H Koppelman Anita L Kozyrskyj Eskil Kreiner Michiaki Kubo Rajesh Kumar Ashish Kumar Mikko Kuokkanen Lies Lahousse Tarja Laitinen Catherine Laprise Mark Lathrop Susanne Lau Young-Ae Lee Terho Lehtimäki Sébastien Letort Albert M Levin Guo Li Liming Liang Laura R Loehr Stephanie J London Daan W Loth Ani Manichaikul Ingo Marenholz Fernando J Martinez Melanie C Matheson Rasika A Mathias Kenji Matsumoto Hamdi Mbarek Wendy L McArdle Mads Melbye Erik Melén Deborah Meyers Sven Michel Hamida Mohamdi Arthur W Musk Rachel A Myers Maartje A E Nieuwenhuis Emiko Noguchi George T O'Connor Ludmila M Ogorodova Cameron D Palmer Aarno Palotie Julie E Park Craig E Pennell Göran Pershagen Alexey Polonikov Dirkje S Postma Nicole Probst-Hensch Valery P Puzyrev Benjamin A Raby Olli T Raitakari Adaikalavan Ramasamy Stephen S Rich Colin F Robertson Isabelle Romieu Muhammad T Salam Veikko Salomaa Vivi Schlünssen Robert Scott Polina A Selivanova Torben Sigsgaard Angela Simpson Valérie Siroux Lewis J Smith Maria Solodilova Marie Standl Kari Stefansson David P Strachan Bruno H Stricker Atsushi Takahashi Philip J Thompson Gudmar Thorleifsson Unnur Thorsteinsdottir Carla M T Tiesler Dara G Torgerson Tatsuhiko Tsunoda André G Uitterlinden Ralf J P van der Valk Amaury Vaysse Sailaja Vedantam Andrea von Berg Erika von Mutius Judith M Vonk Johannes Waage Nick J Wareham Scott T Weiss Wendy B White Magnus Wickman Elisabeth Widén Gonneke Willemsen L Keoki Williams Inge M Wouters James J Yang Jing Hua Zhao Miriam F Moffatt Carole Ober Dan L Nicolae

Nat Genet 2018 01 22;50(1):42-53. Epub 2017 Dec 22.

Departments of Statistics, Human Genetics and Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA.

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http://www.nature.com/articles/s41588-017-0014-7
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http://dx.doi.org/10.1038/s41588-017-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901974PMC
January 2018

Assessing the utilization of radiotherapy near end of life at a Finnish University Hospital: a retrospective cohort study.

Acta Oncol 2017 Oct 13;56(10):1265-1271. Epub 2017 May 13.

a Department of Oncology and Radiotherapy , Turku University Hospital , Turku , Finland.

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http://dx.doi.org/10.1080/0284186X.2017.1324638DOI Listing
October 2017

End-of-life chemotherapy use at a Finnish university hospital: a retrospective cohort study.

Acta Oncol 2017 Oct 31;56(10):1272-1276. Epub 2017 May 31.

a Department of Oncology and Radiotherapy , Turku University Hospital , Turku , Finland.

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http://dx.doi.org/10.1080/0284186X.2017.1332424DOI Listing
October 2017

Characterization of sputum biomarkers for asthma-COPD overlap syndrome.

Int J Chron Obstruct Pulmon Dis 2016 30;11:2457-2465. Epub 2016 Sep 30.

Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.2147/COPD.S113484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053388PMC
August 2017

Telemonitoring of CPAP therapy may save nursing time.

Sleep Breath 2016 Dec 4;20(4):1209-1215. Epub 2016 Apr 4.

Division of Medicine, Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.1007/s11325-016-1337-9DOI Listing
December 2016

CHRNA5/CHRNA3 Locus Associates with Increased Mortality among Smokers.

COPD 2016 08 11;13(4):464-70. Epub 2016 Jan 11.

a Department of Pulmonary Diseases and Clinical Allergology , University of Turku and Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.3109/15412555.2015.1049260DOI Listing
August 2016

Individual FEV1 Trajectories Can Be Identified from a COPD Cohort.

COPD 2016 08 25;13(4):425-30. Epub 2016 Jan 25.

a Clinical Research Unit for Pulmonary Diseases and Division of Pulmonology , Helsinki University Central Hospital , Helsinki , Finland.

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http://dx.doi.org/10.3109/15412555.2015.1043423DOI Listing
August 2016

High Adherence to CPAP Treatment Does Not Prevent the Continuation of Weight Gain among Severely Obese OSAS Patients.

J Clin Sleep Med 2016 Apr 15;12(4):519-28. Epub 2016 Apr 15.

Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital and University of Turku, Finland.

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http://dx.doi.org/10.5664/jcsm.5680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795278PMC
April 2016

Physical activity in COPD patients decreases short-acting bronchodilator use and the number of exacerbations.

Respir Med 2015 Oct 6;109(10):1320-5. Epub 2015 Aug 6.

Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital and University of Turku, Finland.

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http://dx.doi.org/10.1016/j.rmed.2015.08.001DOI Listing
October 2015

Association between all-cause and cause-specific mortality and the GOLD stages 1-4: A 30-year follow-up among Finnish adults.

Respir Med 2015 Aug 9;109(8):1012-8. Epub 2015 Jun 9.

National Institute for Health and Welfare, PO Box 30, 00271 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2015.06.002DOI Listing
August 2015

Accurate genetic diagnosis of Finnish pulmonary arterial hypertension patients using oligonucleotide-selective sequencing.

Mol Genet Genomic Med 2015 Jul 25;3(4):354-62. Epub 2015 Apr 25.

Blueprint Genetics Helsinki, Finland ; Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki Helsinki, Finland.

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http://doi.wiley.com/10.1002/mgg3.147
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http://dx.doi.org/10.1002/mgg3.147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521970PMC
July 2015

Long-term smoking increases the need for acute care among asthma patients: a case control study.

BMC Pulm Med 2014 Jul 16;14:119. Epub 2014 Jul 16.

Skin and Allergy Hospital, Helsinki University Central Hospital, PO Box 160, FI-00029 HUS Helsinki, Finland.

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http://bmcpulmmed.biomedcentral.com/articles/10.1186/1471-24
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http://dx.doi.org/10.1186/1471-2466-14-119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108236PMC
July 2014

Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD.

BMC Pulm Med 2014 Jun 19;14:102. Epub 2014 Jun 19.

Clinical Research Unit for Pulmonary Diseases and Division of Pulmonology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1186/1471-2466-14-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229911PMC
June 2014

Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap.

Eur Respir J 2014 Feb 21;43(2):421-9. Epub 2013 Jun 21.

Pulmonary Division, University of Helsinki and Helsinki University Central Hospital, Helsinki.

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http://dx.doi.org/10.1183/09031936.00024313DOI Listing
February 2014

Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100IU/ml.

Peptides 2014 Jan 13;51:100-9. Epub 2013 Nov 13.

The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland; Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland and University of Tampere, Tampere, Finland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01969781130037
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http://dx.doi.org/10.1016/j.peptides.2013.10.030DOI Listing
January 2014

[Chronic obstructive pulmonary disease (COPD) phenotypes].

Duodecim 2013 ;129(2):127-36

HYKS, Keuhkosairauksien klinikka, Meilahden sairaala.

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July 2013

Physical inactivity in COPD and increased patient perception of dyspnea.

Int J Chron Obstruct Pulmon Dis 2012 29;7:743-55. Epub 2012 Oct 29.

Clinical Research Unit for Pulmonary Diseases and Division of Pulmonology, Helsinki University Central Hospital, and Department of Sports and Exercise Medicine, Institute of Clinical Medicine, Helsinki University, Helsinki, Finland.

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http://dx.doi.org/10.2147/COPD.S35497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496537PMC
April 2013

Bayesian predictors of very poor health related quality of life and mortality in patients with COPD.

BMC Med Inform Decis Mak 2013 Mar 7;13:34. Epub 2013 Mar 7.

Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1186/1472-6947-13-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610236PMC
March 2013

Low socioeconomic status is associated with chronic obstructive airway diseases.

Respir Med 2011 Aug 2;105(8):1140-6. Epub 2011 Apr 2.

University of Tampere, Department of Nursing Science, Niittytie 1, FI-33470 Ylöjärvi, Finland.

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http://dx.doi.org/10.1016/j.rmed.2011.03.008DOI Listing
August 2011

Overlap syndrome of asthma and COPD predicts low quality of life.

J Asthma 2011 Apr 17;48(3):279-85. Epub 2011 Feb 17.

Department of Allergology, Skin and Allergy Hospital, Helsinki, Finland.

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http://dx.doi.org/10.3109/02770903.2011.555576DOI Listing
April 2011

Comparison between the disease-specific Airways Questionnaire 20 and the generic 15D instruments in COPD.

Health Qual Life Outcomes 2011 Jan 16;9. Epub 2011 Jan 16.

Department of Medicine, Pulmonary Division, Helsinki University Central Hospital, Haartmaninkatu 4, Helsinki, Finland.

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http://dx.doi.org/10.1186/1477-7525-9-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031191PMC
January 2011

ELMOD2, a candidate gene for idiopathic pulmonary fibrosis, regulates antiviral responses.

FASEB J 2010 Apr 4;24(4):1167-77. Epub 2009 Dec 4.

Department of Medical Genetics, Biomedicum Helsinki, P.O. Box 63, 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1096/fj.09-138545DOI Listing
April 2010

Cellular characteristics of non-allergic eosinophilic conjunctivitis.

Acta Ophthalmol 2010 Mar 23;88(2):245-50. Epub 2009 Nov 23.

Optokari Ltd, Espoo, Finland.

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http://dx.doi.org/10.1111/j.1755-3768.2009.01599.xDOI Listing
March 2010

Hereditary hemorrhagic telangiectasia type 1 and 2 mutations in Finland.

Acta Otolaryngol 2008 Nov;128(11):1238-41

Department of Medical Genetics, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1080/00016480801908035DOI Listing
November 2008

Gene mapping in asthma-related traits.

Authors:
Tarja Laitinen

Methods Mol Biol 2007 ;376:213-34

GeneOS Ltd., Tukholmankatu, Helsinki, Finland.

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http://dx.doi.org/10.1007/978-1-59745-389-9_15DOI Listing
December 2007

Downstream target genes of the neuropeptide S-NPSR1 pathway.

Hum Mol Genet 2006 Oct 22;15(19):2923-35. Epub 2006 Aug 22.

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Finland, and Department of Biosciences and Nutrition, Clinical Research Centre, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.

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http://dx.doi.org/10.1093/hmg/ddl234DOI Listing
October 2006

Neuropeptide S and G protein-coupled receptor 154 modulate macrophage immune responses.

Hum Mol Genet 2006 May 6;15(10):1667-79. Epub 2006 Apr 6.

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1093/hmg/ddl090DOI Listing
May 2006

Characterization of GPRA, a novel G protein-coupled receptor related to asthma.

Am J Respir Cell Mol Biol 2005 Sep 9;33(3):262-70. Epub 2005 Jun 9.

Department of Medical Genetics, Biomedicum Helsinki, Haartman Institute, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1165/rcmb.2004-0405OCDOI Listing
September 2005

[Molecular genetics provides novel insights to the treatment of asthma].

Authors:
Tarja Laitinen

Duodecim 2004 ;120(20):2373-4

Helsingin yliopisto.

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June 2005

Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma.

Am J Respir Crit Care Med 2005 May 11;171(10):1089-95. Epub 2005 Feb 11.

Institute of Environmental Medicine, Centre for Allergy Research, and Department of Biosciences, Karolinska Institutet, Box 210, Stockholm SE-171 77, Sweden.

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http://dx.doi.org/10.1164/rccm.200410-1317OCDOI Listing
May 2005

The polymorphism C5507G of complement receptor 1 does not explain idiopathic pulmonary fibrosis among the Finns.

Respir Med 2005 Mar;99(3):265-7

Department of Pulmonary Medicine, Helsinki University Hospital, Pulmonary Clinic, Haartmaninkatu 4, 00029 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.rmed.2004.08.003DOI Listing
March 2005

Positionally cloned susceptibility genes in allergy and asthma.

Curr Opin Immunol 2004 Dec;16(6):689-94

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.coi.2004.09.011DOI Listing
December 2004

[Isolation of free DNA from archived serum samples suitable for molecular genetic studies].

Orv Hetil 2004 Nov;145(47):2375-8

Semmelweis Egyetem, Altalános Orvostudományi Kar, I. Szülészeti és Nogyógyászati Klinika, Budapest.

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November 2004

Searching for links between endotoxin exposure and pregnancy loss: CD14 polymorphism in idiopathic recurrent miscarriage.

Am J Reprod Immunol 2003 Oct;50(4):346-50

Department of Medical Microbiology, University of Oulu, Finland.

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http://dx.doi.org/10.1034/j.1600-0897.2003.00092.xDOI Listing
October 2003

IL-1 receptor antagonist gene polymorphism in recurrent spontaneous abortion.

J Reprod Immunol 2003 Feb;58(1):61-7

Clinical Microbiology Laboratory, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1016/s0165-0378(02)00044-xDOI Listing
February 2003

Susceptibility loci for preeclampsia on chromosomes 2p25 and 9p13 in Finnish families.

Am J Hum Genet 2003 Jan 9;72(1):168-77. Epub 2002 Dec 9.

Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1086/345311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC378622PMC
January 2003

Physical map of an asthma susceptibility locus in 7p15-p14 and an association study of TCRG.

Eur J Hum Genet 2002 Oct;10(10):658-65

Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Finland.

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http://dx.doi.org/10.1038/sj.ejhg.5200861DOI Listing
October 2002

The value of isolated populations in genetic studies of allergic diseases.

Authors:
Tarja Laitinen

Curr Opin Allergy Clin Immunol 2002 Oct;2(5):379-82

Department of Medical Genetics, Biomedicum Helsinki, Finland.

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http://dx.doi.org/10.1097/00130832-200210000-00002DOI Listing
October 2002

Characterization of a de novo conversion in human complement C4 gene producing a C4B5-like protein.

J Immunol 2002 Jun;168(11):5652-8

Department of Tissue Typing, Finnish Red Cross Blood Transfusion Service, Helsinki, Finland. Department of Medical Genetics, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.4049/jimmunol.168.11.5652DOI Listing
June 2002