Publications by authors named "Tarik Tihan"

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Utility of Pit-1 Immunostaining in Distinguishing Pituitary Adenomas of Primitive Differentiation from Null Cell Adenomas.
Endocr Pathol 2017 Dec;28(4):287-292
Division of Neuropathology, Department of Pathology, University of California, 505 Parnassus Ave, Room M-551, Box 0102, San Francisco, CA, 94143, USA.


Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Cancer Cell 2016 Dec;30(6):891-908
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

SOX10 Distinguishes Pilocytic and Pilomyxoid Astrocytomas From Ependymomas but Shows No Differences in Expression Level in Ependymomas From Infants Versus Older Children or Among Molecular Subgroups.
J Neuropathol Exp Neurol 2016 Apr 4;75(4):295-8. Epub 2016 Mar 4.
From the Department of Pathology (BKKD, AMR); Department of Neurology (BKKD); and Department of Neurosurgery, University of Colorado Health Sciences Center (BKKD), Aurora, Colorado; Department of Neuro-Oncology, Children's Hospital Colorado (AMD, NKF), Aurora, Colorado; and Department of Pathology, University of California San Francisco (MP, TT), San Francisco, California.



Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype.
Clin Cancer Res 2015 Aug 8;21(16):3750-8. Epub 2015 May 8.
Developmental & Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada.

Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors.
N Engl J Med 2015 Jun 10;372(26):2499-508. Epub 2015 Jun 10.
From the Departments of Health Sciences Research (J.E.E.-P., P.A.D., H.S., M.L.K.), Laboratory Medicine and Pathology (D.H.L., G.S., A.A.C., T.M.K., C.E.P., A.R.C., C.H., C.G., R.B.J.), Neurology (D.H.L., B.P.O.), and Oncology (J.C.B.), Mayo Clinic, Rochester, MN; the Departments of Neurological Surgery (A.M.M., K.M.W., T.R., I.V.S., H.M.H., L.S.M., S.Z., A.P., M.S.B., S.M.C., M.D.P., J.K.W., M.R.W.), Epidemiology and Biostatistics (A.M.M., P.M.B., J.W., J.K.W., M.R.W.) and Pathology (M.P., R.M., G.F.R., A.P., T.T.) and the Institute of Human Genetics (J.W., J.K.W., M.R.W.), University of California, San Francisco, and the Bioinformatics Core, Gladstone Institutes (A.R.P.) - all in San Francisco; and the Department of Pathology and Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York (J.T.H.).

Silent arteriovenous malformation hemorrhage and the recognition of "unruptured" arteriovenous malformation patients who benefit from surgical intervention.
Neurosurgery 2015 May;76(5):592-600; discussion 600
*Departments of Neurological Surgery, ‡Anesthesia and Perioperative Care, Center for Cerebrovascular Research, §Radiology, and ¶Pathology, University of California, San Francisco, San Francisco, California.

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.
Lancet Oncol 2015 May 14;16(5):569-82. Epub 2015 Apr 14.
Division of Hematology-Oncology, University of Toronto, Toronto, ON, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Electronic address:

Pathologic approach to spinal cord infections.
Neuroimaging Clin N Am 2015 May 20;25(2):163-72. Epub 2015 Feb 20.
Neuropathology Division, Department of Pathology, University of California San Francisco, Room M551, 505 Parnassus Avenue, San Francisco, CA 94143-0102, USA; Koc University School of Medicine, Istanbul, Turkey. Electronic address:

High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN).
Acta Neuropathol 2015 Apr 27;129(4):609-610. Epub 2015 Feb 27.
Division of Neuropathology, Department of Pathology, University of California San Francisco School of Medicine, 505 Parnassus Avenue, San Francisco, CA 94143, USA.

Clinicopathologic features of pediatric oligodendrogliomas: a series of 50 patients.
Am J Surg Pathol 2014 Aug;38(8):1058-70
Departments of *Pathology §Radiology †The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD Departments of ‡Pathology ¶Neurological Surgery, University of California San Francisco School of Medicine, San Francisco, CA ∥Hospital Pathology Associates, Minneapolis, St Paul, MN #University of Arizona, College of Medicine, Phoenix, AZ.

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Nat Genet 2014 Jul 8;46(7):731-5. Epub 2014 Jun 8.
1] Division of Neuroepidemiology, Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA. [2] Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA.

Pathology of spinal ependymomas: an institutional experience over 25 years in 134 patients.
Neurosurgery 2013 Aug;73(2):247-55; discussion 255
*Department of Neurosurgery, University of California, San Francisco, San Francisco, California; ‡Department of Pathology, University of California, San Francisco, San Francisco, California.




Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy.
Proc Natl Acad Sci U S A 2013 Apr 29;110(16):E1480-9. Epub 2013 Mar 29.
Department of Pathology, Neurology, Neurological Surgery, and Pediatrics, Sandler Neurosciences Center, and Brain Tumor Research Center, University of California, San Francisco, CA 94158, USA.

Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.
Arterioscler Thromb Vasc Biol 2013 Feb 13;33(2):305-10. Epub 2012 Dec 13.
Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, CA 94110, USA




Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome.
Neuro Oncol 2017 01 9;19(1):78-88. Epub 2016 Jun 9.
Department of Radiation Oncology, University of California San Francisco, San Francisco, California (D.R.R., S.A.L., A.L., M.A.G., P.K.S., D.A.H.-K.); Division of Neuropathology, Department of Pathology, University of California San Francisco, San Francisco, California (D.A.S., T.T.); Department of Neurology, University of California San Francisco, San Francisco, California (J.L.C.); Department of Neurologic Surgery, University of California San Francisco, San Francisco, California (J.L.C., M.W.M., M.S.B.)


Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages.
Stroke 2017 10 30;48(10):2881-2884. Epub 2017 Aug 30.
From Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research (X.C., J.N., H.S., H.K.), Department of Radiology and Biomedical Imaging (D.L.C., D.S., C.H.), Department of Neurological Surgery (M.T.L.), and Department of Pathology (T.T.), University of California, San Francisco; and Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, China (X.C., Y.Z.).


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