Publications by authors named "Taraka R Donti"

19Publications

Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway.

Authors:
Brian J Shayota Taraka R Donti Jing Xiao Charul Gijavanekar Adam D Kennedy Leroy Hubert Lance Rodan Christina Vanderpluym Catherine Nowak Hans T Bjornsson Rebecca Ganetzky Gerard T Berry Kirk L Pappan V Reid Sutton Qin Sun Sarah H Elsea

Mol Genet Metab 2020 Sep - Oct;131(1-2):147-154. Epub 2020 Aug 5.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Baylor Genetics, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
August 2020

Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice.

Authors:
Tim L Emmerzaal Graeme Preston Bram Geenen Vivienne Verweij Maximilian Wiesmann Elisavet Vasileiou Femke Grüter Corné de Groot Jeroen Schoorl Renske de Veer Monica Roelofs Martijn Arts Yara Hendriksen Eva Klimars Taraka R Donti Brett H Graham Eva Morava Richard J Rodenburg Tamas Kozicz

Transl Psychiatry 2020 06 1;10(1):176. Epub 2020 Jun 1.

Department of Anatomy, Radboud University Medical Center, Donders Institute for Brain Cognition and Behaviour, Nijmegen, The Netherlands.

View Article and Find Full Text PDF
June 2020

Opening a window on lysosomal acid lipase deficiency: Biochemical, molecular, and epidemiological insights.

Authors:
Gerarda Cappuccio Taraka R Donti Leroy Hubert Qin Sun Sarah H Elsea

J Inherit Metab Dis 2019 05 5;42(3):509-518. Epub 2019 Mar 5.

Department of Translational Medical Sciences, Section of Pediatrics, Federico II University, Naples, Italy.

View Article and Find Full Text PDF
May 2019

A metabolomic map of Zellweger spectrum disorders reveals novel disease biomarkers.

Authors:
Michael F Wangler Leroy Hubert Taraka R Donti Meredith J Ventura Marcus J Miller Nancy Braverman Kelly Gawron Mousumi Bose Ann B Moser Richard O Jones William B Rizzo V Reid Sutton Qin Sun Adam D Kennedy Sarah H Elsea

Genet Med 2018 10 8;20(10):1274-1283. Epub 2018 Feb 8.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA.

View Article and Find Full Text PDF
October 2018

Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay.

Authors:
Adam D Kennedy Kirk L Pappan Taraka R Donti Anne M Evans Jacob E Wulff Luke A D Miller V Reid Sutton Qin Sun Marcus J Miller Sarah H Elsea

Mol Genet Metab 2017 06 9;121(2):83-90. Epub 2017 Apr 9.

Dept. of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
June 2017

Expansion of the Phenotypic Spectrum of Propionic Acidemia with Isolated Elevated Propionylcarnitine.

Authors:
Gerarda Cappuccio Paldeep S Atwal Taraka R Donti Kiki Ugarte Nadia Merchant William J Craigen V Reid Sutton Sarah H Elsea

JIMD Rep 2017 30;35:33-37. Epub 2016 Nov 30.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.

View Article and Find Full Text PDF
November 2016

Diagnosis of adenylosuccinate lyase deficiency by metabolomic profiling in plasma reveals a phenotypic spectrum.

Authors:
Taraka R Donti Gerarda Cappuccio Leroy Hubert Juanita Neira Paldeep S Atwal Marcus J Miller Aaron L Cardon V Reid Sutton Brenda E Porter Fiona M Baumer Michael F Wangler Qin Sun Lisa T Emrick Sarah H Elsea

Mol Genet Metab Rep 2016 Sep 27;8:61-6. Epub 2016 Jul 27.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.

View Article and Find Full Text PDF
September 2016

Expanding the phenotypic spectrum of Succinyl-CoA ligase deficiency through functional validation of a new SUCLG1 variant.

Authors:
Taraka R Donti Ruchi Masand Daryl A Scott William J Craigen Brett H Graham

Mol Genet Metab 2016 09 25;119(1-2):68-74. Epub 2016 Jul 25.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
September 2016

Holocarboxylase synthetase deficiency pre and post newborn screening.

Authors:
Taraka R Donti Patrick R Blackburn Paldeep S Atwal

Mol Genet Metab Rep 2016 Jun 6;7:40-4. Epub 2016 Apr 6.

Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, United States; Department of Clinical Genomics, Center for Individualized Medicine, Mayo Clinic, Jacksonville, FL, United States.

View Article and Find Full Text PDF
June 2016

Functional cellular analyses reveal energy metabolism defect and mitochondrial DNA depletion in a case of mitochondrial aconitase deficiency.

Authors:
Roa Sadat Emanuele Barca Ruchi Masand Taraka R Donti Ali Naini Darryl C De Vivo Salvatore DiMauro Neil A Hanchard Brett H Graham

Mol Genet Metab 2016 May 8;118(1):28-34. Epub 2016 Mar 8.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
May 2016

Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions.

Authors:
Marcus J Miller Bret L Bostwick Adam D Kennedy Taraka R Donti Qin Sun V Reid Sutton Sarah H Elsea

JIMD Rep 2016 3;30:39-44. Epub 2016 Mar 3.

Department of Molecular and Human Genetics, Medical Genetics Laboratory, Baylor College of Medicine, Houston, TX, 77030, USA.

View Article and Find Full Text PDF
March 2016

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.

Authors:
Jun Hyoung Park Sajna Vithayathil Santosh Kumar Pi-Lin Sung Lacey Elizabeth Dobrolecki Vasanta Putluri Vadiraja B Bhat Salil Kumar Bhowmik Vineet Gupta Kavisha Arora Danli Wu Efrosini Tsouko Yiqun Zhang Suman Maity Taraka R Donti Brett H Graham Daniel E Frigo Cristian Coarfa Patricia Yotnda Nagireddy Putluri Arun Sreekumar Michael T Lewis Chad J Creighton Lee-Jun C Wong Benny Abraham Kaipparettu

Cell Rep 2016 Mar 25;14(9):2154-2165. Epub 2016 Feb 25.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

View Article and Find Full Text PDF
March 2016

Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure.

Authors:
San-Pin Wu Chung-Yang Kao Leiming Wang Chad J Creighton Jin Yang Taraka R Donti Romain Harmancey Hernan G Vasquez Brett H Graham Hugo J Bellen Heinrich Taegtmeyer Ching-Pin Chang Ming-Jer Tsai Sophia Y Tsai

Nat Commun 2015 Sep 10;6:8245. Epub 2015 Sep 10.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article and Find Full Text PDF
September 2015

Aromatic L-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma.

Authors:
Paldeep S Atwal Taraka R Donti Aaron L Cardon C A Bacino Qin Sun L Emrick V Reid Sutton Sarah H Elsea

Mol Genet Metab 2015 Jun-Jul;115(2-3):91-4. Epub 2015 May 2.

Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
March 2016

Mitochondrial myopathy, lactic acidosis, and sideroblastic anemia (MLASA) plus associated with a novel de novo mutation (m.8969G>A) in the mitochondrial encoded ATP6 gene.

Authors:
Lindsay C Burrage Sha Tang Jing Wang Taraka R Donti Magdalena Walkiewicz J Michael Luchak Li-Chieh Chen Eric S Schmitt Zhiyv Niu Rodrigo Erana Jill V Hunter Brett H Graham Lee-Jun Wong Fernando Scaglia

Mol Genet Metab 2014 Nov 30;113(3):207-12. Epub 2014 Jun 30.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

View Article and Find Full Text PDF
November 2014

Transglutaminase 2 reprogramming of glucose metabolism in mammary epithelial cells via activation of inflammatory signaling pathways.

Authors:
Santosh Kumar Taraka R Donti Navneet Agnihotri Kapil Mehta

Int J Cancer 2014 Jun 30;134(12):2798-807. Epub 2014 Jan 30.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX.

View Article and Find Full Text PDF
June 2014

Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion.

Authors:
Taraka R Donti Carmen Stromberger Ming Ge Karen W Eldin William J Craigen Brett H Graham

Dis Model Mech 2014 Feb 21;7(2):271-80. Epub 2013 Nov 21.

Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article and Find Full Text PDF
February 2014

Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins.

Authors:
Taraka R Donti Shibani Datta Pamela Y Sandoval Geoffrey M Kapler

EMBO J 2009 Feb 15;28(3):223-33. Epub 2009 Jan 15.

Department of Molecular and Cellular Medicine, Texas A&M Health Science Center, College Station, TX, USA.

View Article and Find Full Text PDF
February 2009

Tetrahymena ORC contains a ribosomal RNA fragment that participates in rDNA origin recognition.

Authors:
Mohammad M Mohammad Taraka R Donti J Sebastian Yakisich Aaron G Smith Geoffrey M Kapler

EMBO J 2007 Dec 15;26(24):5048-60. Epub 2007 Nov 15.

Department of Molecular and Cellular Medicine, Texas A&M Health Science Center, College Station, TX 77843-1114, USA.

View Article and Find Full Text PDF
December 2007