Taofeek Owonikoko

Taofeek Owonikoko

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Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation.

J Clin Invest 2019 Oct;129(10):4110-4123

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI125963DOI Listing
October 2019

Inhibition of mTOR complex 1/p70 S6 kinase signaling elevates PD-L1 levels in human cancer cells through enhancing protein stabilization accompanied with enhanced β-TrCP degradation.

Oncogene 2019 Aug 17;38(35):6270-6282. Epub 2019 Jul 17.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/s41388-019-0877-4DOI Listing
August 2019

The clinical conundrum of managing relapsed small cell lung cancer.

Cancer 2019 Apr 18;125(7):1022-1026. Epub 2018 Dec 18.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.31849DOI Listing
April 2019

Enrollment of Racial Minorities in Clinical Trials: Old Problem Assumes New Urgency in the Age of Immunotherapy.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:3-10. Epub 2019 May 17.

1 Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1200/EDBK_100021DOI Listing
January 2019

Randomized, Double-Blind, Phase II Study of Temozolomide in Combination With Either Veliparib or Placebo in Patients With Relapsed-Sensitive or Refractory Small-Cell Lung Cancer.

J Clin Oncol 2018 08 15;36(23):2386-2394. Epub 2018 Jun 15.

M. Catherine Pietanza, Lee M. Krug, Mark G. Kris, and Charles M. Rudin, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College; Kaitlin M. Woo, Yevgeniva Bensman, Brenda Hurtado, and Martin Fleisher, Memorial Sloan Kettering Cancer Center, New York, NY; Saiama N. Waqar, Washington University School of Medicine in St. Louis, St Louis, MO; Afshin Dowlati, Case Western Reserve University and University Hospitals Seidman Cancer Center, Cleveland, OH; Christine L. Hann, Johns Hopkins University, Baltimore; Alice Chen, National Institutes of Health, Bethesda, MD; Alberto Chiappori, H. Lee Moffitt Cancer Center, Tampa, FL; Taofeek K. Owonikoko, Emory University, Atlanta, GA; and Robert J. Cardnell, Junya Fujimoto, Lihong Long, Lixia Diao, Jing Wang, Patricia de Groot, Erik P. Sulman, Ignacio I. Wistuba, John V. Heymach, and Lauren Averett Byers, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2018.77.7672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085179PMC
August 2018

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma.

N Engl J Med 2018 07 4;379(4):341-351. Epub 2018 Jun 4.

From the Departments of Dermatology and Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston (M.R.M.), and South Texas Accelerated Research Therapeutics (START), San Antonio (K.P.P.) - both in Texas; the Department of Medical Oncology, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC (D.R., A.A.T.), the Department of Medical Oncology, Royal North Shore Hospital, St. Leonards, VIC (A.G.), the Department of Medical Oncology, Sir Charles Gairdner Hospital, Perth, WA (A.M.L.), and Royal Brisbane and Women's Hospital and University of Queensland, Brisbane (B.G.M.H.) - all in Australia; the Department of Dermatology, Brigham and Women's Hospital (C.D.S.), the Department of Dermatology, Harvard Medical School (C.D.S.), and the Department of Medical Oncology, Dana-Farber Cancer Institute (G.R.) - all in Boston; Schleswig-Holstein University Hospital, Kiel (A.H.), and University Hospital Essen, Essen and German Cancer Consortium, Essen (D.S.) - both in Germany; University of Colorado Denver, School of Medicine, Aurora (K.D.L.); the Departments of Head and Neck-Endocrine Oncology (C.H.C.) and Cutaneous Oncology (N.I.K.), H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; the Division of Medical Oncology, Department of Medicine, Washington University School of Medicine, St. Louis (L.H.-A.); the Department of Dermatology, Stanford University School of Medicine, Redwood City (A.L.S.C.), and the Division of Dermatology, City of Hope, Duarte (B.M.) - both in California; the Department of Medicine, Head and Neck Medical Oncology, Memorial Sloan Kettering Cancer Center, New York (L.A.D.), and Regeneron Pharmaceuticals, Tarrytown (F.S., M.M., K.M., G.D.Y., I.L., M.G.F.) - both in New York; Regeneron Pharmaceuticals, Basking Ridge, NJ (B.G., S.L., J.L., J.B., E.S.); University of Arizona Cancer Center, Tucson (H.M.B.), and Banner MD Anderson Cancer (J.H.) and the Department of Medical Oncology, Banner MD Anderson Cancer Center (J.N.), Gilbert - all in Arizona; Medical Oncology Department, Vall D'Hebron University Hospital (I.B.), and Institut Català D'Oncologia, Oncobell Program (IDIBELL), L'Hospitalet de Llobregat (M.G.-M.), Barcelona, and START Madrid-FJD, Hospital Fundación Jiménez Díaz, Madrid (V.M.) - all in Spain; Sarah Cannon Research Institute, Nashville (M.L.J.); and the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta (T.K.O.).

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http://www.nejm.org/doi/10.1056/NEJMoa1805131
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http://dx.doi.org/10.1056/NEJMoa1805131DOI Listing
July 2018

Orthopedia homeobox is preferentially expressed in typical carcinoids of the lung.

Cancer Cytopathol 2018 04 9;126(4):236-242. Epub 2018 Jan 9.

Department of Pathology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncy.21969DOI Listing
April 2018

Immunotherapy of lung cancer.

J Thorac Dis 2018 Feb;10(Suppl 3):S395-S396

Associate Guest Editor, Associate Professor, Chief, Thoracic Oncology, Department of Medicine, Fox Chase Cancer Center/Temple University, Philadelphia, PA, USA. (Email:

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http://dx.doi.org/10.21037/jtd.2018.01.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861270PMC
February 2018

Immune checkpoint inhibitors in small cell lung cancer.

J Thorac Dis 2018 Feb;10(Suppl 3):S460-S467

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.21037/jtd.2017.12.51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861263PMC
February 2018

Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.

J Clin Invest 2018 01 11;128(1):500-516. Epub 2017 Dec 11.

Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI92742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749500PMC
January 2018

The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer.

Mol Cell 2018 01 14;69(1):87-99.e7. Epub 2017 Dec 14.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777230PMC
January 2018

PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients.

PLoS One 2017 27;12(9):e0184254. Epub 2017 Sep 27.

Department of Hematology and Medical Oncology, Division of Stem Cell and Bone Marrow Transplantation, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184254PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617147PMC
October 2017

Pulmonary Sarcomatoid Carcinoma: An Analysis of the National Cancer Data Base.

Clin Lung Cancer 2017 05 7;18(3):286-292. Epub 2016 Dec 7.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.11.016DOI Listing
May 2017

Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report.

Cancer Immunol Immunother 2017 01 22;66(1):45-50. Epub 2016 Oct 22.

Department of Hematology and Medical Oncology, Emory University School of Medicine, 1365-C Clifton Road, NE, Suite C3080, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1007/s00262-016-1918-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588660PMC
January 2017

National Cancer Database Analysis of Proton Versus Photon Radiation Therapy in Non-Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2017 01 11;97(1):128-137. Epub 2016 Oct 11.

Winship Cancer Institute, Emory University, Atlanta, Georgia; Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.ijrobp.2016.10.001DOI Listing
January 2017

Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.

Mol Cell 2016 12 17;64(5):859-874. Epub 2016 Nov 17.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135630PMC
December 2016

Systemic treatment and management approaches for medullary thyroid cancer.

Cancer Treat Rev 2016 Nov 10;50:89-98. Epub 2016 Sep 10.

Department of Hematology/Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, 1365-C Clifton Road NE, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2016.09.006DOI Listing
November 2016

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.

Cancer Lett 2016 10 19;380(2):494-504. Epub 2016 Jul 19.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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http://search.proquest.com/openview/96fc37bbd6ea5af450a03f13
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http://dx.doi.org/10.1016/j.canlet.2016.07.021DOI Listing
October 2016

Lung Adenocarcinoma Staging Using the 2011 IASLC/ATS/ERS Classification: A Pooled Analysis of Adenocarcinoma In Situ and Minimally Invasive Adenocarcinoma.

Clin Lung Cancer 2016 09 30;17(5):e57-e64. Epub 2016 Mar 30.

Department of Pathology and Laboratory Medicine, Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.03.009DOI Listing
September 2016

EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.

Cancer Discov 2016 06 21;6(6):601-11. Epub 2016 Apr 21.

Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee. Addario Lung Cancer Medical Institute, Cambridge, Massachusetts. Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893907PMC
June 2016

Mannitol to prevent cisplatin-induced nephrotoxicity in patients with squamous cell cancer of the head and neck (SCCHN) receiving concurrent therapy.

Support Care Cancer 2016 Apr 7;24(4):1789-93. Epub 2015 Oct 7.

Department of Hematology and Medical Oncology, School of Medicine, Emory University, Atlanta, GA, USA.

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http://link.springer.com/10.1007/s00520-015-2978-0
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http://dx.doi.org/10.1007/s00520-015-2978-0DOI Listing
April 2016

Targeting the PI3K/AKT/mTOR pathway: biomarkers of success and tribulation.

Am Soc Clin Oncol Educ Book 2013

From the Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1200/EdBook_AM.2013.33.e395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821994PMC
November 2015

Biomarkers and targeted systemic therapies in advanced non-small cell lung cancer.

Mol Aspects Med 2015 Nov 14;45:55-66. Epub 2015 Jul 14.

Department of Hematology & Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00982997150004
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http://dx.doi.org/10.1016/j.mam.2015.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637259PMC
November 2015

Inhibitors of mTOR pathway for cancer therapy, moving on from rapalogs to TORKinibs.

Cancer 2015 Oct 15;121(19):3390-2. Epub 2015 Jul 15.

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http://dx.doi.org/10.1002/cncr.29424DOI Listing
October 2015

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Cancer Lett 2015 Aug 29;364(1):70-8. Epub 2015 Apr 29.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835150030
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http://dx.doi.org/10.1016/j.canlet.2015.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450809PMC
August 2015

Bevacizumab in Combination with Taxane versus Non-Taxane Containing Regimens for Advanced/Metastatic Nonsquamous Non-Small-Cell Lung Cancer: A Systematic Review.

J Thorac Oncol 2015 Aug;10(8):1142-7

*Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia; †Winship Cancer Institute of Emory University, Atlanta, Georgia; ‡Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California; §Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia; and ‖Penn State Hershey Cancer Institute, Hershey, Pennsylvania.

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http://dx.doi.org/10.1097/JTO.0000000000000572DOI Listing
August 2015

A Bystander Effect of Lung Cancer Chemotherapy on Chronic Echinococcal Disease.

World J Oncol 2015 Aug 27;6(4):416-420. Epub 2015 Aug 27.

Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.14740/wjon920wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624690PMC
August 2015

Dose escalation with over-dose and under-dose controls in Phase I/II clinical trials.

Contemp Clin Trials 2015 Jul 24;43:133-41. Epub 2015 May 24.

Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, United States; Biostatistics and Bioinformatics Shared Resource, Winship Cancer Institute, Emory University, Atlanta, GA 30322, United States.

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http://dx.doi.org/10.1016/j.cct.2015.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871606PMC
July 2015

Management patterns and predictors of mortality among US patients with cancer hospitalized for malignant bowel obstruction.

Cancer 2015 Jun 4;121(11):1772-8. Epub 2015 Mar 4.

Division of Gastrointestinal Oncology, Department of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.29297DOI Listing
June 2015

Racial disparities in squamous cell carcinoma of the oral tongue among women: a SEER data analysis.

Oral Oncol 2015 Jun 10;51(6):586-92. Epub 2015 Apr 10.

Department of Hematology and Medical Oncology, The Winship Cancer Institute of Emory University, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2015.03.010DOI Listing
June 2015

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.

Cancer Cell 2015 Jun 21;27(6):852-63. Epub 2015 May 21.

Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470473PMC
June 2015

Predictors and outcomes of venous thromboembolism in hospitalized lung cancer patients: A Nationwide Inpatient Sample database analysis.

Lung Cancer 2015 Apr 2;88(1):80-4. Epub 2015 Feb 2.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.lungcan.2015.01.022DOI Listing
April 2015

GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growth.

Oncotarget 2015 Apr;6(11):8974-87

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496196PMC
http://dx.doi.org/10.18632/oncotarget.3291DOI Listing
April 2015

Atypical carcinoid tumor of the lung: a surveillance, epidemiology, and end results database analysis.

J Thorac Oncol 2015 Mar;10(3):479-85

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1097/JTO.0000000000000419DOI Listing
March 2015

Postoperative radiotherapy is associated with better survival in non-small cell lung cancer with involved N2 lymph nodes: results of an analysis of the National Cancer Data Base.

J Thorac Oncol 2015 Mar;10(3):462-71

Departments of *Radiation Oncology, †Hematology and Oncology, ‡Surgery, §Biostatistics and Bioinformatics Shared Resource, ‖Rollins School of Public Health, and the ¶Winship Cancer Institute, Emory University, Atlanta, GA.

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http://dx.doi.org/10.1097/JTO.0000000000000411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336617PMC
March 2015

Randomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer.

J Clin Oncol 2015 Feb 5;33(5):433-41. Epub 2015 Jan 5.

Suresh S. Ramalingam and Taofeek K. Owonikoko, Winship Cancer Institute of Emory University, Atlanta, GA; Mikhail Shtivelband, Ironwood Cancer and Research Centers, Chandler, AZ; Ross A. Soo, National University Cancer Institute, National University Health System, Singapore, Singapore; Carlos H. Barrios, Pontifícia Universidade Católica do Rio Grande do Sul School of Medicine, Porto Alegre; José G.M. Segalla, Hospital Amaral Carvalho, Jau; Jose R. Pereira, Instituto Brasileiro de Cancerologia Toracica, Sao Paulo, Brazil; Anatoly Makhson, Moscow City Oncology Hospital No. 62; Vera A. Gorbunova, N.N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia; Kenneth B. Pittman, The Queen Elizabeth Hospital, Woodville, South Australia, Australia; Petr Kolman, Hospital Kyjov, Kyjov, Czech Republic; Gordan Srkalovic, Sparrow Regional Cancer Center, Lansing, MI; Chandra P. Belani, Penn State Hershey Cancer Institute, Hershey; Rita Axelrod, Thomas Jefferson University Hospital, Philadelphia, PA; Qin Qin, Jiang Qian, Evelyn M. McKeegan, Viswanath Devanarayan, Mark D. McKee, Justin L. Ricker, and Dawn M. Carlson, AbbVie, North Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2014.55.7173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478045PMC
February 2015

Minimize toxicity or preserve efficacy? A delicate trade-off in the management of older patients with lung cancer.

J Clin Oncol 2015 Feb 12;33(6):534-6. Epub 2015 Jan 12.

Emory University and Winship Cancer Institute, Atlanta, GA

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http://dx.doi.org/10.1200/JCO.2014.59.5033DOI Listing
February 2015

Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation.

Nucleic Acids Res 2015 Jan 7;43(2):960-72. Epub 2015 Jan 7.

Departments of Radiation Oncology, Division of Cancer Biology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, USA

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http://dx.doi.org/10.1093/nar/gku1358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333404PMC
January 2015

Concurrent therapy with taxane versus non-taxane containing regimens in locally advanced squamous cell carcinomas of the head and neck (SCCHN): a systematic review.

Oral Oncol 2014 Sep 22;50(9):888-94. Epub 2014 Jul 22.

Department of Hematology and Medical Oncology, Emory University, Atlanta, GA, United States; Winship Cancer Institute of Emory University, Atlanta, GA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2014.06.014DOI Listing
September 2014

Small-molecule Bax agonists for cancer therapy.

Nat Commun 2014 Sep 17;5:4935. Epub 2014 Sep 17.

1] Department of Medicine, University of Florida, 1600 SW Archer Road, Gainesville, Florida 32610, USA [2] Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, 1365C Clifton Road NE, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1038/ncomms5935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172359PMC
September 2014

Escalation with overdose control using all toxicities and time to event toxicity data in cancer Phase I clinical trials.

Contemp Clin Trials 2014 Mar 12;37(2):322-32. Epub 2014 Feb 12.

Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, United States; Biostatistics and Bioinformatics Shared Resource, Winship Cancer Institute, Emory University, Atlanta, GA 30322, United States.

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http://dx.doi.org/10.1016/j.cct.2014.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046505PMC
March 2014

Small cell lung cancer: therapies and targets.

Semin Oncol 2014 Feb 12;41(1):133-42. Epub 2013 Dec 12.

Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2013.12.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176613PMC
February 2014

Bcl2 induces DNA replication stress by inhibiting ribonucleotide reductase.

Cancer Res 2014 Jan 6;74(1):212-23. Epub 2013 Nov 6.

Authors' Affiliations: Departments of Radiation Oncology, Hematology and Medical Oncology, and Biochemistry, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, Georgia; and Department of Clinical and Molecular Pharmacology, City of Hope National Medical Center, Duarte, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1536-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887143PMC
January 2014

Altered glutamine metabolism and therapeutic opportunities for lung cancer.

Clin Lung Cancer 2014 Jan 13;15(1):7-15. Epub 2013 Nov 13.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970234PMC
January 2014

Taxanes: vesicants, irritants, or just irritating?

Ther Adv Med Oncol 2014 Jan;6(1):16-20

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1177/1758834013510546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866993PMC
January 2014

Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer.

Mol Cancer Ther 2013 Oct 26;12(10):2200-12. Epub 2013 Jul 26.

Corresponding Author: Xingming Deng, Division of Cancer Biology, Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA 30322.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795834PMC
October 2013

Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

Cancer Res 2013 Sep 3;73(17):5485-96. Epub 2013 Jul 3.

Departments of Radiation Oncology, Hematology and Medical Oncology, and Pathology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774010PMC
September 2013

Interactive Software "Isotonic Design using Normalized Equivalent Toxicity Score (ID-NETS©TM)" for Cancer Phase I Clinical Trials.

Open Med Inform J 2013 5;7:8-17. Epub 2013 Apr 5.

Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA ; Biostatistics and Bioinformatics Shared Resource at Winship Cancer Institute, GA 30322, USA.

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http://dx.doi.org/10.2174/1874431101307010008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680993PMC
July 2013