Tanya Paquet

Tanya Paquet

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Tanya Paquet

Tanya Paquet

Publications by authors named "Tanya Paquet"

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20Publications

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Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801.

Medchemcomm 2019 Dec 17;10(12):2118-2125. Epub 2019 Oct 17.

Department of Biochemistry , Stellenbosch University , Private Bag X1 , Matieland 7602 , South Africa . Email:

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http://dx.doi.org/10.1039/c9md00312fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069524PMC
December 2019

Investigating Sulfoxide-to-Sulfone Conversion as a Prodrug Strategy for a Phosphatidylinositol 4-Kinase Inhibitor in a Humanized Mouse Model of Malaria.

Antimicrob Agents Chemother 2018 12 26;62(12). Epub 2018 Nov 26.

Drug Discovery and Development Centre (H3D), Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Observatory, South Africa

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http://dx.doi.org/10.1128/AAC.00261-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256810PMC
December 2018

Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidines.

J Med Chem 2015 Sep 8;58(18):7572-9. Epub 2015 Sep 8.

Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town , Rondebosch, Cape Town 7701, South Africa.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01156DOI Listing
September 2015

Structure-activity relationship studies of antiplasmodial aminomethylthiazoles.

Bioorg Med Chem Lett 2014 Nov 2;24(22):5207-11. Epub 2014 Oct 2.

Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, University of Cape Town, Rondebosch 7701, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2014.09.071DOI Listing
November 2014

Antimalarial aminothiazoles and aminopyridines from phenotypic whole-cell screening of a SoftFocus(®) library.

Future Med Chem 2012 Dec;4(18):2265-77

Department of Chemistry, University of Cape Town, Private Bag X3, Rondebosch 7701, South Africa.

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http://dx.doi.org/10.4155/fmc.12.176DOI Listing
December 2012

Synthesis of the macrocyclic core of leiodermatolide.

Org Lett 2011 Aug 14;13(16):4398-401. Epub 2011 Jul 14.

University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK.

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https://pubs.acs.org/doi/10.1021/ol2017388
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http://dx.doi.org/10.1021/ol2017388DOI Listing
August 2011

Total synthesis and configurational validation of (+)-phorbaside A.

Org Lett 2010 May;12(9):2158-61

University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK.

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http://dx.doi.org/10.1021/ol100693cDOI Listing
May 2010