Publications by authors named "Tannishtha Reya"

49Publications

MARCH Proteins Mediate Responses to Antitumor Antibodies.

J Immunol 2020 Nov 19;205(10):2883-2892. Epub 2020 Oct 19.

Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA 92093; and

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http://dx.doi.org/10.4049/jimmunol.1901245DOI Listing
November 2020

Stem cells in cancer initiation and progression.

J Cell Biol 2020 01;219(1)

Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla, CA.

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http://dx.doi.org/10.1083/jcb.201911053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039188PMC
January 2020

A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.

Cell 2019 04 4;177(3):572-586.e22. Epub 2019 Apr 4.

Department of Pharmacology, University of California, San Diego School of Medicine, La Jolla, CA, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA; Moores Cancer Center, University of California, San Diego School of Medicine, La Jolla, CA, USA; Department of Medicine, University of California, San Diego School of Medicine, La Jolla, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193027
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http://dx.doi.org/10.1016/j.cell.2019.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711371PMC
April 2019

Stem cell fate in cancer growth, progression and therapy resistance.

Nat Rev Cancer 2018 11;18(11):669-680

Departments of Pharmacology and Medicine, San Diego School of Medicine, University of California, La Jolla, CA, USA.

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http://dx.doi.org/10.1038/s41568-018-0056-xDOI Listing
November 2018

Epigenetic and Transcriptomic Profiling of Mammary Gland Development and Tumor Models Disclose Regulators of Cell State Plasticity.

Cancer Cell 2018 09 30;34(3):466-482.e6. Epub 2018 Aug 30.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152943PMC
September 2018

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.

Cancer Cell 2017 Dec 16;32(6):824-839.e8. Epub 2017 Nov 16.

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Pathology, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730340PMC
December 2017

Glucose feeds the TCA cycle via circulating lactate.

Nature 2017 11 18;551(7678):115-118. Epub 2017 Oct 18.

Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA.

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http://dx.doi.org/10.1038/nature24057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898814PMC
November 2017

CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.

Cancer Cell 2016 Nov 27;30(5):792-805. Epub 2016 Oct 27.

Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA 92093, USA; Sanford Consortium for Regenerative Medicine, La Jolla, CA 92037, USA; Moores Cancer Center, University of California San Diego School of Medicine, La Jolla, CA 92093, USA; Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137811PMC
November 2016

High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo.

Nat Commun 2016 07 18;7:12169. Epub 2016 Jul 18.

Departments of Pharmacology and Medicine, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/ncomms12169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960315PMC
July 2016

Delayed Onset of Symptoms Through Feedback Interference in Chronic Cancers.

Converg Sci Phys Oncol 2016 21;2(4). Epub 2016 Oct 21.

Department of Medicine, University of California, San Diego, La Jolla, CA.

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http://dx.doi.org/10.1088/2057-1739/2/4/045002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937283PMC
October 2016

Fearful symmetry: subversion of asymmetric division in cancer development and progression.

Cancer Res 2015 Mar 13;75(5):792-7. Epub 2015 Feb 13.

Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, California. Sanford Consortium for Regenerative Medicine, La Jolla, California. Moores Cancer Center, University of California San Diego School of Medicine, La Jolla, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784538PMC
March 2015

Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.

Genes Dev 2014 May;28(9):995-1004

Department of Pharmacology, University of California at San Diego School of Medicine, La Jolla, California 92093, USA;

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http://dx.doi.org/10.1101/gad.231944.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018497PMC
May 2014

Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia.

Nat Genet 2014 Mar 2;46(3):245-52. Epub 2014 Feb 2.

1] Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, California, USA. [2] Sanford Consortium for Regenerative Medicine, La Jolla, California, USA. [3] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA. [4] Moores Cancer Center, University of California San Diego School of Medicine, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.2889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267534PMC
March 2014

Wnt signaling in normal and malignant hematopoiesis.

Cold Spring Harb Perspect Biol 2013 Feb 1;5(2). Epub 2013 Feb 1.

Division of Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1101/cshperspect.a008011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552513PMC
February 2013

Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

Proc Natl Acad Sci U S A 2013 Feb 16;110(6):2300-5. Epub 2013 Jan 16.

Department of Pharmacology and Toxicology, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA.

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http://dx.doi.org/10.1073/pnas.1206551110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568344PMC
February 2013

β-Arrestin2 mediates the initiation and progression of myeloid leukemia.

Proc Natl Acad Sci U S A 2012 Jul 5;109(31):12532-7. Epub 2012 Jul 5.

Department of Pharmacology, University of California, San Diego School of Medicine and Sanford Consortium for Regenerative Medicine, La Jolla, CA 92093.

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http://dx.doi.org/10.1073/pnas.1209815109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411976PMC
July 2012

aSIRTing control over cancer stem cells.

Cancer Cell 2012 Feb;21(2):140-2

Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.01.014DOI Listing
February 2012

Illuminating immune privilege--a role for regulatory T cells in preventing rejection.

Authors:
Tannishtha Reya

N Engl J Med 2011 Sep;365(10):956-7

University of California, San Diego, School of Medicine, La Jolla, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMcibr1107781
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http://dx.doi.org/10.1056/NEJMcibr1107781DOI Listing
September 2011

Inhibition of apoptosome formation by suppression of Hsp90beta phosphorylation in tyrosine kinase-induced leukemias.

Mol Cell Biol 2008 Sep 30;28(17):5494-506. Epub 2008 Jun 30.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Box 3813, Durham, NC 27710, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.00265-08
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http://dx.doi.org/10.1128/MCB.00265-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519729PMC
September 2008

Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system.

Curr Opin Immunol 2008 Jun 12;20(3):302-7. Epub 2008 Jun 12.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.coi.2008.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2560983PMC
June 2008

Imaging hematopoietic precursor division in real time.

Cell Stem Cell 2007 Nov;1(5):541-54

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.stem.2007.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267762PMC
November 2007

Activation of Wnt signaling in hematopoietic regeneration.

Stem Cells 2008 May 28;26(5):1202-10. Epub 2008 Feb 28.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1634/stemcells.2007-0768DOI Listing
May 2008

Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo.

Cancer Cell 2007 Dec;12(6):528-41

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.ccr.2007.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2262869PMC
December 2007

Identification of adiponectin as a novel hemopoietic stem cell growth factor.

J Immunol 2007 Mar;178(6):3511-20

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.4049/jimmunol.178.6.3511DOI Listing
March 2007

Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance.

J Biol Chem 2005 Sep 14;280(39):33101-8. Epub 2005 Jul 14.

Department of Pharmacology and Cancer Biology, Duke University, Medical Center, Durham, North Carolina 27715, USA.

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http://www.jimmunol.org/content/181/7/5015.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M505208200
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http://dx.doi.org/10.1074/jbc.M505208200DOI Listing
September 2005

Wnt signalling in stem cells and cancer.

Nature 2005 Apr;434(7035):843-50

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.sci.sjp.ac.lk/lms/file.php/312/Wnt_Signalling_Rea
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http://www.nature.com/doifinder/10.1038/nature03319
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http://dx.doi.org/10.1038/nature03319DOI Listing
April 2005

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.

Nat Immunol 2005 Mar 23;6(3):314-22. Epub 2005 Jan 23.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.reyalab.org/manage/user_files/5-1225364707.pdf
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http://www.nature.com/doifinder/10.1038/ni1164
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http://dx.doi.org/10.1038/ni1164DOI Listing
March 2005

Frizzled 9 knock-out mice have abnormal B-cell development.

Blood 2005 Mar 30;105(6):2487-94. Epub 2004 Nov 30.

Departments of Pathology and Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1182/blood-2004-06-2334DOI Listing
March 2005

Wnt signaling in the stem cell niche.

Curr Opin Hematol 2004 Mar;11(2):88-94

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1097/01.moh.0000133649.61121.ecDOI Listing
March 2004

The elements of stem cell self-renewal: a genetic perspective.

Biotechniques 2003 Dec;35(6):1240-7

Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.2144/03356ss03DOI Listing
December 2003

Regulation of hematopoietic stem cell self-renewal.

Authors:
Tannishtha Reya

Recent Prog Horm Res 2003 ;58:283-95

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1210/rp.58.1.283DOI Listing
July 2003

Wnt proteins are lipid-modified and can act as stem cell growth factors.

Nature 2003 May 27;423(6938):448-52. Epub 2003 Apr 27.

Howard Hughes Medical Institute and Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

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http://www.nature.com/articles/nature01611
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http://dx.doi.org/10.1038/nature01611DOI Listing
May 2003

A role for Wnt signalling in self-renewal of haematopoietic stem cells.

Nature 2003 May 27;423(6938):409-14. Epub 2003 Apr 27.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.nature.com/articles/nature01593
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http://dx.doi.org/10.1038/nature01593DOI Listing
May 2003