Tammy Gillis

Tammy Gillis

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Tammy Gillis

Tammy Gillis

Publications by authors named "Tammy Gillis"

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42Publications

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Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.

Am J Hum Genet 2018 09 16;103(3):349-357. Epub 2018 Aug 16.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Medical and Population Genetics Program, the Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524551/
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https://linkinghub.elsevier.com/retrieve/pii/S00029297183024
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http://dx.doi.org/10.1016/j.ajhg.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128248PMC
September 2018

Haplotype-based stratification of Huntington's disease.

Eur J Hum Genet 2017 11 23;25(11):1202-1209. Epub 2017 Aug 23.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/ejhg.2017.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643960PMC
November 2017

A modifier of Huntington's disease onset at the MLH1 locus.

Hum Mol Genet 2017 10;26(19):3859-3867

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddx286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455020PMC
October 2017

A novel neurodevelopmental disorder associated with compound heterozygous variants in the huntingtin gene.

Eur J Hum Genet 2016 12 22;24(12):1826-1827. Epub 2016 Jun 22.

Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.

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http://www.nature.com/articles/ejhg201674
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http://dx.doi.org/10.1038/ejhg.2016.74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117927PMC
December 2016

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.

Hum Mol Genet 2016 10;25(20):4566-4576

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1093/hmg/ddw286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078600PMC
October 2016

The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease.

Am J Hum Genet 2016 Feb;98(2):287-98

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Neurology, Harvard Medical School, Boston, MA 02115, USA; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Genetic Modifiers of Huntington's Disease Consortium. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746370PMC
February 2016

Sequence-Level Analysis of the Major European Huntington Disease Haplotype.

Am J Hum Genet 2015 Sep 27;97(3):435-44. Epub 2015 Aug 27.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2015.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564985PMC
September 2015

Prevalence of Huntington's disease gene CAG trinucleotide repeat alleles in patients with bipolar disorder.

Bipolar Disord 2015 Jun 26;17(4):403-8. Epub 2015 Feb 26.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1111/bdi.12289DOI Listing
June 2015

Haplotype analysis of the 4p16.3 region in Portuguese families with Huntington's disease.

Am J Med Genet B Neuropsychiatr Genet 2015 Mar 5;168B(2):135-43. Epub 2015 Feb 5.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA; UnIGENe, IBMC-Institute for Molecular and Cell Biology, University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1002/ajmg.b.32289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006842PMC
March 2015

Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.

Hum Mol Genet 2009 Aug 23;18(16):3039-47. Epub 2009 May 23.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddp242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714728PMC
August 2009

Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington's disease.

Neurobiol Dis 2006 Nov 7;24(2):280-5. Epub 2006 Sep 7.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, and Department of Neurology, Boston University School of Medicine, MA 02114, USA.

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http://dx.doi.org/10.1016/j.nbd.2006.07.008DOI Listing
November 2006

Genetic analysis of the GRIK2 modifier effect in Huntington's disease.

BMC Neurosci 2006 Sep 7;7:62. Epub 2006 Sep 7.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1186/1471-2202-7-62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618398PMC
September 2006

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.

Hum Mol Genet 2006 Jun 10;15(12):2015-24. Epub 2006 May 10.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1093/hmg/ddl125DOI Listing
June 2006

Biotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3.

Am J Hum Genet 2005 Jul 3;77(1):16-26. Epub 2005 May 3.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Charlestown, MA 02129-2000, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970760898
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http://dx.doi.org/10.1086/431216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226189PMC
July 2005