Tammie Benzinger

Tammie Benzinger

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Tammie Benzinger

Publications by authors named "Tammie Benzinger"

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Differences in Driving Outcomes Among Cognitively Normal African American and Caucasian Older Adults.

J Racial Ethn Health Disparities 2019 Nov 4. Epub 2019 Nov 4.

Charles F. and Joanne Knight Alzheimer's Disease Research Center, 660 S. Euclid Ave., Campus Box, St. Louis, MO, 8111, USA.

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http://dx.doi.org/10.1007/s40615-019-00655-zDOI Listing
November 2019

Automated production of a sphingosine-1 phosphate receptor 1 (S1P1) PET radiopharmaceutical [C]CS1P1 for human use.

Appl Radiat Isot 2019 Oct 20;152:30-36. Epub 2019 Jun 20.

Department of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.apradiso.2019.06.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708718PMC
October 2019

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis.

Neurology 2019 Oct 1;93(17):e1647-e1659. Epub 2019 Aug 1.

From the Department of Neurology (S.E.S., J.G.B., V.O., K.G.M., D.M.H., J.C.M., T.L.S.B., C.X., A.M.F., R.J.B.), Knight Alzheimer's Disease Research Center (S.E.S., B.A.G., D.M.H., J.C.M., T.L.S.B., C.X., A.M.F., R.J.B.), Division of Biostatistics (Y.L., C.X.), Mallinckrodt Institute of Radiology (B.A.G., T.L.S.B.), and Hope Center for Neurological Disorders (D.M.H., A.M.F., R.J.B.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000008081DOI Listing
October 2019

The interactions of dopamine and oxidative damage in the striatum of patients with neurodegenerative diseases.

J Neurochem 2019 Oct 15. Epub 2019 Oct 15.

Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1111/jnc.14898DOI Listing
October 2019

Association between personality and tau-PET binding in cognitively normal older adults.

Brain Imaging Behav 2019 Sep 5. Epub 2019 Sep 5.

Department of Radiology, Washington University School of Medicine, St. Louis, USA.

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http://dx.doi.org/10.1007/s11682-019-00163-yDOI Listing
September 2019

A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials.

Alzheimers Dement 2019 Sep 7. Epub 2019 Sep 7.

Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Departments of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.06.4955DOI Listing
September 2019

Translocator protein in late stage Alzheimer's disease and Dementia with Lewy bodies brains.

Ann Clin Transl Neurol 2019 Aug 9;6(8):1423-1434. Epub 2019 Jul 9.

Department of Neurology, Washington University School of Medicine, 510 S. Kingshighway Blvd, St. Louis, Missouri, 63110.

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http://dx.doi.org/10.1002/acn3.50837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689696PMC
August 2019

Neuroinflammation and Myelin Status in Alzheimer's Disease, Parkinson's Disease, and Normal Aging Brains: A Small Sample Study.

Parkinsons Dis 2019 4;2019:7975407. Epub 2019 Jul 4.

Department of Radiology, Washington University School of Medicine, 510 S, Kingshighway Blvd, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1155/2019/7975407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637678PMC
July 2019

Progression of Low-Grade Glioma During Pregnancy With Subsequent Regression Postpartum Without Treatment-A Case Report.

Neurosurgery 2019 Jun;84(6):E430-E436

Department of Neurosurgery, Washington University in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1093/neuros/nyy191DOI Listing
June 2019

Acute Rodent Tolerability, Toxicity, and Radiation Dosimetry Estimates of the S1P1-Specific Radioligand [C]CS1P1.

Mol Imaging Biol 2019 Jun 4. Epub 2019 Jun 4.

Department of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s11307-019-01380-zDOI Listing
June 2019

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2019 May 4;15(5):655-665. Epub 2019 Mar 4.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511459PMC
May 2019

MRI safety risks in the obese: The case of the disposable lighter stored in the pannus.

Radiol Case Rep 2019 May 15;14(5):634-638. Epub 2019 Mar 15.

Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, MO 63110, US.

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http://dx.doi.org/10.1016/j.radcr.2019.02.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424094PMC
May 2019

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset.

Alzheimers Dement 2019 Apr 15;15(4):506-514. Epub 2019 Feb 15.

Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461496PMC
April 2019

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network.

Neurobiol Aging 2019 03 13;75:42-50. Epub 2018 Oct 13.

Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO; Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183037
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385602PMC
March 2019

The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Mol Psychiatry 2019 Mar 21. Epub 2019 Mar 21.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.

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http://dx.doi.org/10.1038/s41380-019-0404-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754794PMC
March 2019

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer's disease.

Neuroimage Clin 2019 13;22:101767. Epub 2019 Mar 13.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, 4488 Forest Park, Suite 101, St. Louis, MO 63108, USA; Department of Neurosurgery, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.nicl.2019.101767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428957PMC
March 2019

The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study.

Neuroimage Clin 2019 28;22:101795. Epub 2019 Mar 28.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Nuclear Medicine, Peking University First Hospital, Beijing, China; Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, United States. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449776PMC
March 2019

Persistent metabolic youth in the aging female brain.

Proc Natl Acad Sci U S A 2019 02 4;116(8):3251-3255. Epub 2019 Feb 4.

Neuroimaging Laboratories, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1815917116
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http://dx.doi.org/10.1073/pnas.1815917116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386682PMC
February 2019

Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies.

Neuroimage Clin 2018 25;19:406-416. Epub 2018 Apr 25.

Department of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.nicl.2018.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051499PMC
January 2019

Widespread distribution of tauopathy in preclinical Alzheimer's disease.

Neurobiol Aging 2018 12 1;72:177-185. Epub 2018 Sep 1.

Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO; Department of Radiology, Washington University School of Medicine, St. Louis, MO; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO; Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422832PMC
December 2018

Cerebrospinal fluid biomarkers measured by Elecsys assays compared to amyloid imaging.

Alzheimers Dement 2018 11 2;14(11):1460-1469. Epub 2018 Mar 2.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119652PMC
November 2018

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2018 11 25;14(11):1427-1437. Epub 2018 Sep 25.

Section for Dementia Research, Department of Cellular Neurology, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.jalz.2018.06.3059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322213PMC
November 2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease.

Neurology 2018 10 14;91(14):e1295-e1306. Epub 2018 Sep 14.

From the Department of Neurology (E.M., J.H., V.B., A.M.F., D.M.H., J.C.M., K.P., R.J.B.), Division of Biostatistics (G.W., C.X.), Department of Radiology (B.A.G., T.L.S.B., D.S.M.), and Department of Pathology (N.J.C.), Washington University School of Medicine, Saint Louis, MO; Department of Neuroscience (A.M.J.), Icahn School of Medicine at Mount Sinai, New York, NY; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI) (R.A.), Instituto de Investigaciones Neurológicas Raúl Correa, Buenos Aires, Argentina; University of Pittsburgh School of Medicine (S.B.B., W.K.), PA; College of Physicians and Surgeons (J.N.), Columbia University, New York, NY; Department of Neurology (J.R.), Keck School of Medicine of University of Southern California, Los Angeles; Department of Neurology (B.G., M.F.), Indiana University, Indianapolis; Massachusetts General Hospital (R.A.S., J.C.), Harvard Medical School, Boston; Butler Hospital and Brown University (S.S.), Providence, RI; Department of Neurology (N.R.G.-R.), Mayo Clinic Jacksonville, FL; Neuroscience Research Australia (P.R.S.); School of Medical Sciences (P.R.S.), University of New South Wales, Sydney; The Florey Institute and the University of Melbourne (C.M.), Parkville, Australia; Dementia Research Centre, Institute of Neurology (M.N.R., N.C.F.), University College London, UK; German Center for Neurodegenerative Diseases (DZNE) Munich (J.L.); Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) Tübingen (M.J.); and Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177272PMC
October 2018

Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease.

Neurology 2018 08 1;91(9):e859-e866. Epub 2018 Aug 1.

From the Charles F. and Joanne Knight Alzheimer Disease Research Center (A.J.A., B.A.G., T.L.S.B., J.C.M., J.J.H.), Department of Neurology (J.C.M., J.J.H.), Department of Psychological & Brain Sciences (B.A.G., J.J.H.), and Department of Radiology (B.A.G., T.L.S.B.), Washington University in St. Louis, MO.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133625PMC
August 2018

Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease.

Neurobiol Aging 2018 07 20;67:95-98. Epub 2018 Mar 20.

Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955846PMC
July 2018

Loss of white matter integrity reflects tau accumulation in Alzheimer disease defined regions.

Neurology 2018 07 29;91(4):e313-e318. Epub 2018 Jun 29.

From the Department of Neurology (J.F.S., R.X.S., H.B., C.M.R., S.M., B.A., J.C.M., B.M.A.), Department of Radiology (B.A.G., J.J.C., Y.S., T.L.S.B., B.M.A.), Knight Alzheimer's Disease Research Center (B.A.G., J.C.M., T.L.S.B., B.M.A.), Department of Pathology (J.C.M.), and Hope Center for Neurological Disorders (J.C.M., B.M.A.), Washington University in St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000005864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070383PMC
July 2018

Using the A/T/N Framework to Examine Driving in Preclinical AD.

Geriatrics (Basel) 2018 Jun 2;3(2). Epub 2018 May 2.

Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.3390/geriatrics3020023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964600PMC
June 2018

Data-driven models of dominantly-inherited Alzheimer's disease progression.

Brain 2018 05;141(5):1529-1544

Progression of Neurodegenerative Disease Group, Centre for Medical Image Computing, Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/brain/awy050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920320PMC
May 2018

In vivo [F]-AV-1451 tau-PET imaging in sporadic Creutzfeldt-Jakob disease.

Neurology 2018 03 7;90(10):e896-e906. Epub 2018 Feb 7.

From The Charles F. and Joanne Knight Alzheimer Disease Research Center (G.S.D., B.A.G., R.J.P., N.J.C., H.B., E.S.M., N.G., J.C.M., T.L.S.B., B.M.A.), Department of Neurology (G.S.D., R.B., E.S.M., N.G., J.C.M., B.M.A.), Mallinckrodt Institute of Radiology (B.A.G., H.B., M.R.P., B.V., S.M., K.J., T.L.S.B., B.M.A.), and Department of Pathology (R.J.P., N.J.C., K.S., C.F., N.S., J.C.M.), Washington University School of Medicine (G.S.D., B.A.G., R.J.P., N.J.C., H.B., K.S., C.F., N.S., R.B., E.S.M., N.G., M.R.P., B.V., S.M., K.J., J.C.M., T.L.S.B., B.M.A.), St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000005064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863493PMC
March 2018

Tau Kinetics in Neurons and the Human Central Nervous System.

Neuron 2018 03;97(6):1284-1298.e7

Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA; Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273183013
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http://dx.doi.org/10.1016/j.neuron.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137722PMC
March 2018

Diffusion Tensor Imaging as a Biomarker to Differentiate Acute Disseminated Encephalomyelitis From Multiple Sclerosis at First Demyelination.

Pediatr Neurol 2018 01 28;78:70-74. Epub 2017 Sep 28.

Department of Pediatric and Developmental Neurology, Washington University School of Medicine, St. Louis, Missouri. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2017.09.016DOI Listing
January 2018

Depression and Alzheimer's Disease Biomarkers Predict Driving Decline.

J Alzheimers Dis 2018 ;66(3):1213-1221

Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University, School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.3233/JAD-180564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330210PMC
January 2018

Tau-PET Binding Distinguishes Patients With Early-stage Posterior Cortical Atrophy From Amnestic Alzheimer Disease Dementia.

Alzheimer Dis Assoc Disord 2017 Apr-Jun;31(2):87-93

*The Charles F and Joanne Knight Alzheimer Disease Research Center †Department of Neurology ‡Mallinckrodt Institute of Radiology §Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1097/WAD.0000000000000196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443698PMC
December 2017

Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals.

Alzheimer Dis Assoc Disord 2017 Jan-Mar;31(1):69-72

*Charles F. and Joanne Knight Alzheimer's Disease Research Center Departments of †Neurology ‡Occupational Therapy ∥Psychology ¶¶Pathology and Immunology ##Physical Therapy **Radiology §§Neurosurgery ∥∥Medicine ¶Center for Clinical Studies #Division of Biostatistics, Washington University School of Medicine, St. Louis, MO §The Rehabilitation Institute of St. Louis ††The Alzheimer's Disease & Memory Disorders Center, Alpert Medical School of Brown University ‡‡Rhode Island Hospital, Providence, Rhode Island.

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http://dx.doi.org/10.1097/WAD.0000000000000154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085874PMC
November 2017

AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure.

Neuroimage 2017 11 26;161:171-178. Epub 2017 Jul 26.

Department of Radiology, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA; Department of Neurological Surgery, Washington University in St. Louis, School of Medicine, 510 S. Kingshighway, MC 8131, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2017.07.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696044PMC
November 2017

Resting-state Functional Magnetic Resonance Imaging in Presurgical Functional Mapping: Sensorimotor Localization.

Neuroimaging Clin N Am 2017 Nov;27(4):621-633

Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, Saint Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nic.2017.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773116PMC
November 2017

Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis.

Alzheimers Dement 2017 Aug 19;13(8):841-849. Epub 2017 Jul 19.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.06.2266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567785PMC
August 2017

Loss of Brain Aerobic Glycolysis in Normal Human Aging.

Cell Metab 2017 Aug;26(2):353-360.e3

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131173043
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http://dx.doi.org/10.1016/j.cmet.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573225PMC
August 2017

Neurologic Applications of PET/MR Imaging.

Magn Reson Imaging Clin N Am 2017 May 26;25(2):297-313. Epub 2017 Jan 26.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, Campus Box 8131, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.mric.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485669PMC
May 2017

Quantitative hemodynamic PET imaging using image-derived arterial input function and a PET/MR hybrid scanner.

J Cereb Blood Flow Metab 2017 Apr 1;37(4):1435-1446. Epub 2016 Jan 1.

1 Mallinckrodt Institute of Radiology, Washington University School of Medicine, USA.

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http://dx.doi.org/10.1177/0271678X16656200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453463PMC
April 2017

Multimodality Review of Amyloid-related Diseases of the Central Nervous System.

Radiographics 2016 Jul-Aug;36(4):1147-63

From the Mallinckrodt Institute of Radiology (M.M.M.T., A.L.S., T.L.S.B., J.M., S.C.) and Department of Pathology and Immunology (K.E.S.), Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8131, St Louis, MO 63110.

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http://dx.doi.org/10.1148/rg.2016150172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976469PMC
March 2017

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease.

Neurobiol Aging 2017 01 3;49:216.e7-216.e13. Epub 2016 Oct 3.

Alzheimer's Disease Center, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA; Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA; McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154842PMC
January 2017

Mood Changes in Cognitively Normal Older Adults are Linked to Alzheimer Disease Biomarker Levels.

Am J Geriatr Psychiatry 2016 11 19;24(11):1095-1104. Epub 2016 Apr 19.

Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO; Departments of Neurology, Washington University School of Medicine, St. Louis, MO.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069099PMC
http://dx.doi.org/10.1016/j.jagp.2016.04.004DOI Listing
November 2016

Widespread white matter and conduction defects in PSEN1-related spastic paraparesis.

Neurobiol Aging 2016 11 8;47:201-209. Epub 2016 Aug 8.

Department of Neurology, Keck School of Medicine of USC Center for the Health Professionals, Los Angeles, CA, USA; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Mary S. Easton Center for Alzheimer's Disease Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075491PMC
http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.030DOI Listing
November 2016

Longitudinal β-Amyloid Deposition and Hippocampal Volume in Preclinical Alzheimer Disease and Suspected Non-Alzheimer Disease Pathophysiology.

JAMA Neurol 2016 Oct;73(10):1192-1200

Department of Radiology, Washington University, St Louis, Missouri2Knight Alzheimer's Disease Research Center, Washington University, St Louis, Missouri6Department of Neurological Surgery, Washington University, St Louis, Missouri.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2016.2642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237381PMC
October 2016

Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease.

Ann Neurol 2016 09 25;80(3):379-87. Epub 2016 Jul 25.

Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO.

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http://dx.doi.org/10.1002/ana.24719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016232PMC
September 2016

Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy.

JAMA Neurol 2016 09;73(9):1070-7

Department of Neurology, Washington University, St Louis, Missouri2The Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University, St Louis, Missouri3Department of Radiology, Washington University, St Louis, Missouri5The Hope Center for Neurological Disorders at Washington University, St Louis, Missouri.

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http://dx.doi.org/10.1001/jamaneurol.2016.2078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237382PMC
September 2016

The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging.

Brain 2016 08 10;139(Pt 8):2249-60. Epub 2016 Jun 10.

1 Department of Radiology, Washington University in St. Louis, 660 South Euclid Avenue, St. Louis, Missouri 63110, USA 2 Knight Alzheimer's Disease Research Center, Washington University in St. Louis, 4488 Forest Park Avenue, St. Louis, Missouri 63110, USA 6 Department of Neurological Surgery, Washington University in St. Louis, 660 South Euclid Avenue, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1093/brain/aww139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958902PMC
August 2016

NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers.

Neurobiol Aging 2016 08 4;44:1-8. Epub 2016 Apr 4.

Department of Radiology, Washington University School of Medicine, Saint Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, Saint Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO, USA; Department of Neurological Surgery, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913039PMC
August 2016

Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning.

Neurobiol Aging 2016 07 24;43:23-33. Epub 2016 Mar 24.

Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; Department of Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA; Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893196PMC
July 2016

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease.

Sci Transl Med 2016 05;8(338):338ra66

Department of Neurology, Washington University in St. Louis, St. Louis, MO 63110, USA. Department of Radiology, Washington University in St. Louis, St. Louis, MO 63110, USA. Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO 63110, USA. Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaf2362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267531PMC
May 2016

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study.

Neurology 2016 Apr 23;86(16):1499-506. Epub 2016 Mar 23.

From the Charles F. and Joanne Knight Alzheimer's Disease Research Center (C.X., M.S.J., H.W., A.M.F., T.L.S.B., D.H., J.H., E.G., C.L.S., V.B., K.L.M., J.C.M.), Departments of Neurology (V.B., K.L.M., A.M.F., J.H., J.C.M., C.L.S.), Pathology and Immunology (J.C.M.), Physical Therapy (J.C.M.), and Occupational Therapy (J.C.M.), Division of Biostatistics (C.X., M.S.J., H.W., E.G.), and Departments of Psychology (D.H., J.H.), Radiology (T.L.S.B., D.H.), and Neurological Surgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000002593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836885PMC
April 2016