Tammaryn Lashley

Tammaryn Lashley

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Tammaryn Lashley

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White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy.

Acta Neuropathol 2019 Sep 18. Epub 2019 Sep 18.

The Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK.

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http://dx.doi.org/10.1007/s00401-019-02074-0DOI Listing
September 2019

Heritability and genetic variance of dementia with Lewy bodies.

Neurobiol Dis 2019 07 3;127:492-501. Epub 2019 Apr 3.

Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588425PMC
July 2019

A novel mutation in a family with diverse frontotemporal dementia spectrum disorders.

Cold Spring Harb Mol Case Stud 2019 Jun 3;5(3). Epub 2019 Jun 3.

Department of Clinical and Movement Neurosciences, Dementia Research Centre, UCL Queen Square Institute of Neurology, London WC1N 3BG, United Kingdom.

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http://dx.doi.org/10.1101/mcs.a003913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549548PMC
June 2019

A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's disease.

Neurosci Lett 2019 05 23;701:125-131. Epub 2019 Feb 23.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2019.02.033DOI Listing
May 2019

Mass Spectrometric Analysis of Lewy Body-Enriched α-Synuclein in Parkinson's Disease.

J Proteome Res 2019 May 15;18(5):2109-2120. Epub 2019 Apr 15.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry , Sahlgrenska Academy at the University of Gothenburg , S-431 80 Mölndal , Sweden.

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http://dx.doi.org/10.1021/acs.jproteome.8b00982DOI Listing
May 2019

A comprehensive screening of copy number variability in dementia with Lewy bodies.

Neurobiol Aging 2019 03 24;75:223.e1-223.e10. Epub 2018 Oct 24.

Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183038
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541211PMC
March 2019

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

Acta Neuropathol 2019 02 13;137(2):279-296. Epub 2018 Dec 13.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at University of Gothenburg, Göteborgsvägen 31, House V3/SU, 43180, Mölndal, Sweden.

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http://dx.doi.org/10.1007/s00401-018-1948-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514201PMC
February 2019

Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS.

Acta Neuropathol Commun 2019 02 12;7(1):18. Epub 2019 Feb 12.

Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1186/s40478-019-0673-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371513PMC
February 2019

The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.

Acta Neuropathol 2019 01 22;137(1):89-102. Epub 2018 Sep 22.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital/Mölndal, S-431 80, Mölndal, Sweden.

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http://dx.doi.org/10.1007/s00401-018-1910-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338696PMC
January 2019

Immunohistochemical and Molecular Investigations Show Alteration in the Inflammatory Profile of Multiple System Atrophy Brain.

J Neuropathol Exp Neurol 2018 07;77(7):598-607

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1093/jnen/nly035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005028PMC
July 2018

The presubiculum is preserved from neurodegenerative changes in Alzheimer's disease.

Acta Neuropathol Commun 2018 07 20;6(1):62. Epub 2018 Jul 20.

The Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1186/s40478-018-0563-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053705PMC
July 2018

Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.

Cell Rep 2018 07;24(4):987-1000.e7

Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland; Life Science Zurich Graduate School, University of Zurich and ETH Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.094DOI Listing
July 2018

Large inter- and intra-case variability of first generation tau PET ligand binding in neurodegenerative dementias.

Acta Neuropathol Commun 2018 05 1;6(1):34. Epub 2018 May 1.

Institute of Nuclear Medicine and Department of Chemistry, University College London, London, UK.

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http://dx.doi.org/10.1186/s40478-018-0535-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928586PMC
May 2018

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Lancet Neurol 2018 01 16;17(1):64-74. Epub 2017 Dec 16.

UK Dementia Research Institute, University College London, London, UK; Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Institute of Biomedicine, iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30400-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805394PMC
January 2018

Heterogeneous ribonuclear protein E2 (hnRNP E2) is associated with TDP-43-immunoreactive neurites in Semantic Dementia but not with other TDP-43 pathological subtypes of Frontotemporal Lobar Degeneration.

Acta Neuropathol Commun 2017 06 30;5(1):54. Epub 2017 Jun 30.

Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Salford Royal Hospital, M6 8HD, Salford, UK.

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http://dx.doi.org/10.1186/s40478-017-0454-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493127PMC
June 2017

Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration.

Acta Neuropathol Commun 2017 04 18;5(1):29. Epub 2017 Apr 18.

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1186/s40478-017-0432-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395972PMC
April 2017

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Neurobiol Aging 2017 01 2;49:214.e13-214.e15. Epub 2016 Sep 2.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Department of Medical Sciences and Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154872PMC
January 2017

Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer's disease: a case series.

Lancet Neurol 2016 Dec 21;15(13):1326-1335. Epub 2016 Oct 21.

Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(16)30193-4DOI Listing
December 2016

Characterization of tau positron emission tomography tracer [F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias.

Alzheimers Dement 2016 11 15;12(11):1116-1124. Epub 2016 Feb 15.

Institute of Nuclear Medicine and Department of Chemistry, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.01.003DOI Listing
November 2016

The presence of heterogeneous nuclear ribonucleoproteins in frontotemporal lobar degeneration with FUS-positive inclusions.

Neurobiol Aging 2016 10 15;46:192-203. Epub 2016 Jul 15.

The Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, Institute of Neurology, UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.004DOI Listing
October 2016

Apomorphine: A potential modifier of amyloid deposition in Parkinson's disease?

Mov Disord 2016 05 13;31(5):668-75. Epub 2015 Oct 13.

Institute of Neuroscience, Newcastle University, Newcastle, United Kingdom.

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http://dx.doi.org/10.1002/mds.26422DOI Listing
May 2016

Review: an update on clinical, genetic and pathological aspects of frontotemporal lobar degenerations.

Neuropathol Appl Neurobiol 2015 Dec 6;41(7):858-81. Epub 2015 Jul 6.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1111/nan.12250DOI Listing
December 2015

Histological evidence of chronic traumatic encephalopathy in a large series of neurodegenerative diseases.

Acta Neuropathol 2015 Dec 24;130(6):891-3. Epub 2015 Oct 24.

Queen Square Brain Bank for Neurological Studies, UCL Institute of Neurology, 1 Wakefield Street, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00401-015-1496-yDOI Listing
December 2015

Spontaneous ARIA (amyloid-related imaging abnormalities) and cerebral amyloid angiopathy related inflammation in presenilin 1-associated familial Alzheimer's disease.

J Alzheimers Dis 2015 ;44(4):1069-74

Department of Clinical Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JAD-142325DOI Listing
November 2015

Qualitative changes in human γ-secretase underlie familial Alzheimer's disease.

J Exp Med 2015 Nov 19;212(12):2003-13. Epub 2015 Oct 19.

VIB Center for the Biology of Disease, University of Leuven (KU Leuven), 3000 Leuven, Belgium Center for Human Genetics (CME) and Leuven Research Institute for Neuroscience and Disease (LIND), University of Leuven (KU Leuven), 3000 Leuven, Belgium

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http://dx.doi.org/10.1084/jem.20150892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647268PMC
November 2015

Brain amyloid-beta fragment signatures in pathological ageing and Alzheimer's disease by hybrid immunoprecipitation mass spectrometry.

Neurodegener Dis 2015 13;15(1):50-7. Epub 2015 Jan 13.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1159/000369465DOI Listing
July 2015

Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease.

Neuropathol Appl Neurobiol 2015 Jun 23;41(4):497-506. Epub 2015 Apr 23.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1111/nan.12183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879505PMC
June 2015

Temporal Variant Frontotemporal Dementia is Associated with Globular Glial Tauopathy.

Cogn Behav Neurol 2015 Jun;28(2):92-7

*Dementia Research Centre †Queen Square Brain Bank for Neurological Disorders, University College London, Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1097/WNN.0000000000000060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478068PMC
June 2015

C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis.

Lancet Neurol 2015 Mar 29;14(3):291-301. Epub 2015 Jan 29.

Dementia Research Centre, University College London (UCL) Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(14)70233-9DOI Listing
March 2015

Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease.

Alzheimers Res Ther 2014 1;6(5-8):77. Epub 2014 Dec 1.

Dementia Research Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1186/s13195-014-0077-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248436PMC
December 2014

The significance of α-synuclein, amyloid-β and tau pathologies in Parkinson's disease progression and related dementia.

Neurodegener Dis 2014 11;13(2-3):154-6. Epub 2013 Sep 11.

Parkinson Disease and Movement Disorders Unit, Neurology Service, IDIBAPS, CIBERNED, Hospital Clínic, Barcelona, Spain.

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http://dx.doi.org/10.1159/000354670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194631PMC
September 2014

A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia.

Neuropathol Appl Neurobiol 2014 Jun;40(4):502-13

Queen Square Brain Bank, Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1111/nan.12100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260146PMC
June 2014

Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy.

Neurobiol Aging 2014 Jun 30;35(6):1491-8. Epub 2013 Dec 30.

MRC Centre for Neuromuscular Disease, UCL Institute of Neurology, London, UK; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988933PMC
June 2014

C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci.

Acta Neuropathol 2013 Dec 30;126(6):845-57. Epub 2013 Oct 30.

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00401-013-1200-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830745PMC
December 2013

A novel prion disease associated with diarrhea and autonomic neuropathy.

N Engl J Med 2013 Nov;369(20):1904-14

Medical Research Council (MRC) Prion Unit (S.M., J.B., C.C., S.J., J.M.L., H.A.-D., B.S., M.K.S., S.B., J.D.F.W., J.C.), Department of Molecular Neuroscience (S.G., N.W.W.), and Dementia Research Centre, Department of Neurodegenerative Disease (J.D.W.), and MRC Centre for Neuromuscular Diseases (M.M.R.), University College London (UCL) Institute of Neurology; the National Prion Clinic (S.M., D.C., D.G., H.H., P.R., J.C.), National Hospital for Neurology and Neurosurgery (M.K.), UCL Hospitals National Health Service Trust (A.F.); and the Queen Square Brain Bank (H.A., T.L., T.R., J.L.H.) - all in London.

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http://dx.doi.org/10.1056/NEJMoa1214747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863770PMC
November 2013

Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias.

Neurobiol Aging 2013 May 20;34(5):1416-25. Epub 2012 Dec 20.

Division of Molecular Psychiatry, Georg-August-University Goettingen, University Medicine Goettingen, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570712PMC
May 2013

RANTing about C9orf72.

Neuron 2013 Feb;77(4):597-8

Reta Lila Weston Laboratories and Department of Molecular Neuroscience, University College London Institute of Neurology, London WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.neuron.2013.02.009DOI Listing
February 2013

Transportin1: a marker of FTLD-FUS.

Acta Neuropathol 2011 Nov 17;122(5):591-600. Epub 2011 Aug 17.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, UK.

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http://dx.doi.org/10.1007/s00401-011-0863-6DOI Listing
November 2011

Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies.

Acta Neuropathol 2011 Oct 21;122(4):415-28. Epub 2011 Jul 21.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, 1 Wakefield Street, London, WC1N 1PJ, UK.

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http://dx.doi.org/10.1007/s00401-011-0857-4DOI Listing
October 2011

TDP-43 pathology may occur in the BRI2 gene-related dementias.

Acta Neuropathol 2011 Apr 22;121(4):559-60. Epub 2011 Feb 22.

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http://dx.doi.org/10.1007/s00401-011-0811-5DOI Listing
April 2011

PYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM.

Hirosaki Igaku 2010 Jul;61(Suppl):S262-S269

Department of Neurology, University of Tsukuba, Graduate School of Comprehensive Human Science, Tsukuba, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964672PMC
July 2010

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Authors:
Vivianna M Van Deerlin Patrick M A Sleiman Maria Martinez-Lage Alice Chen-Plotkin Li-San Wang Neill R Graff-Radford Dennis W Dickson Rosa Rademakers Bradley F Boeve Murray Grossman Steven E Arnold David M A Mann Stuart M Pickering-Brown Harro Seelaar Peter Heutink John C van Swieten Jill R Murrell Bernardino Ghetti Salvatore Spina Jordan Grafman John Hodges Maria Grazia Spillantini Sid Gilman Andrew P Lieberman Jeffrey A Kaye Randall L Woltjer Eileen H Bigio Marsel Mesulam Safa Al-Sarraj Claire Troakes Roger N Rosenberg Charles L White Isidro Ferrer Albert Lladó Manuela Neumann Hans A Kretzschmar Christine Marie Hulette Kathleen A Welsh-Bohmer Bruce L Miller Ainhoa Alzualde Adolfo Lopez de Munain Ann C McKee Marla Gearing Allan I Levey James J Lah John Hardy Jonathan D Rohrer Tammaryn Lashley Ian R A Mackenzie Howard H Feldman Ronald L Hamilton Steven T Dekosky Julie van der Zee Samir Kumar-Singh Christine Van Broeckhoven Richard Mayeux Jean Paul G Vonsattel Juan C Troncoso Jillian J Kril John B J Kwok Glenda M Halliday Thomas D Bird Paul G Ince Pamela J Shaw Nigel J Cairns John C Morris Catriona Ann McLean Charles DeCarli William G Ellis Stefanie H Freeman Matthew P Frosch John H Growdon Daniel P Perl Mary Sano David A Bennett Julie A Schneider Thomas G Beach Eric M Reiman Bryan K Woodruff Jeffrey Cummings Harry V Vinters Carol A Miller Helena C Chui Irina Alafuzoff Päivi Hartikainen Danielle Seilhean Douglas Galasko Eliezer Masliah Carl W Cotman M Teresa Tuñón M Cristina Caballero Martínez David G Munoz Steven L Carroll Daniel Marson Peter F Riederer Nenad Bogdanovic Gerard D Schellenberg Hakon Hakonarson John Q Trojanowski Virginia M-Y Lee

Nat Genet 2010 Mar 14;42(3):234-9. Epub 2010 Feb 14.

[1] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828525PMC
March 2010

Degeneration in different parkinsonian syndromes relates to astrocyte type and astrocyte protein expression.

J Neuropathol Exp Neurol 2009 Oct;68(10):1073-83

Prince of Wales Medical Research Institute and the University of New South Wales, Barker Street, Randwick, Sydney, Australia.

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http://dx.doi.org/10.1097/NEN.0b013e3181b66f1bDOI Listing
October 2009

TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.

Acta Neuropathol 2009 Sep 28;118(3):359-69. Epub 2009 Mar 28.

Clinical Neuroscience Research Group, Faculty of Medical and Human Sciences, Greater Manchester Neurosciences Centre, School of Translational Medicine, Hope Hospital, University of Manchester, Salford, M6 8HD, UK.

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http://dx.doi.org/10.1007/s00401-009-0526-zDOI Listing
September 2009

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.

Acta Neuropathol 2009 Jul 19;118(1):115-30. Epub 2009 Feb 19.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, Queen Square, London WC1N3BG, UK.

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http://dx.doi.org/10.1007/s00401-009-0501-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844092PMC
July 2009

LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions.

Acta Neuropathol 2008 Dec 21;116(6):639-46. Epub 2008 Oct 21.

Prince of Wales Medical Research Institute, Barker Street, Randwick, NSW, 2031, Australia.

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http://dx.doi.org/10.1007/s00401-008-0446-3DOI Listing
December 2008

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.

Nat Med 2008 May 6;14(5):501-3. Epub 2008 Apr 6.

Neuronal Survival Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Science, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1038/nm1746DOI Listing
May 2008

Cortical alpha-synuclein load is associated with amyloid-beta plaque burden in a subset of Parkinson's disease patients.

Acta Neuropathol 2008 Apr 8;115(4):417-25. Epub 2008 Jan 8.

Queen Square Brain Bank for Neurological Disorders, Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00401-007-0336-0DOI Listing
April 2008

Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11.

Nat Genet 2007 Dec 25;39(12):1434-6. Epub 2007 Nov 25.

Department of Molecular Neuroscience, Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/ng.2007.43DOI Listing
December 2007

DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders.

Neurobiol Dis 2007 Oct 18;28(1):122-32. Epub 2007 Jul 18.

Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, 1, Wakefield Street, WC1N 1PJ, UK.

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http://dx.doi.org/10.1016/j.nbd.2007.07.012DOI Listing
October 2007

Sporadic four-repeat tauopathy with frontotemporal degeneration, parkinsonism and motor neuron disease.

Acta Neuropathol 2005 Dec 22;110(6):600-9. Epub 2005 Nov 22.

Department of Pathology, Brain Research Institute, University of Niigata, 1-757 Asahimachi, 951-8585, Niigata, Japan.

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http://link.springer.com/10.1007/s00401-005-1086-5
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http://dx.doi.org/10.1007/s00401-005-1086-5DOI Listing
December 2005

Failure in heat-shock protein expression in response to UBB+1 protein in progressive supranuclear palsy in humans.

Neurosci Lett 2004 Apr;359(1-2):94-8

Reta Lila Weston Institute of Neurological Studies, University College London, 46 Cleveland Street, London, W1T 4JF, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400400137
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http://dx.doi.org/10.1016/j.neulet.2003.12.127DOI Listing
April 2004

Detecting tau isoforms in archival cases.

Acta Neuropathol 2004 Feb 2;107(2):181-2. Epub 2003 Dec 2.

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http://link.springer.com/10.1007/s00401-003-0795-x
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http://dx.doi.org/10.1007/s00401-003-0795-xDOI Listing
February 2004

Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view.

J Neuropathol Exp Neurol 2003 Sep;62(9):885-98

Queen Square Brain Bank, Department of Molecular Neuroscience and Division of Neuropathology, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1093/jnen/62.9.885DOI Listing
September 2003

Complement activation in chromosome 13 dementias. Similarities with Alzheimer's disease.

J Biol Chem 2002 Dec 17;277(51):49782-90. Epub 2002 Oct 17.

Department of Pathology, School of Medicine, New York University, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1074/jbc.M206448200DOI Listing
December 2002

Sporadic and familial cerebral amyloid angiopathies.

Brain Pathol 2002 Jul;12(3):343-57

Queen Square Brain Bank, Department of Molecular Pathogenesis, University College London, UK.

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http://dx.doi.org/10.1111/j.1750-3639.2002.tb00449.xDOI Listing
July 2002