Tamas Bartfai

Tamas Bartfai

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Tamas Bartfai

Publications by authors named "Tamas Bartfai"

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Midlife interventions are critical in prevention, delay, or improvement of Alzheimer's disease and vascular cognitive impairment and dementia.

F1000Res 2017 3;6:413. Epub 2017 Apr 3.

Department of Psychiatry and Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.12688/f1000research.11140.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399952PMC
April 2017

Cool by neuronal decision.

Authors:
Tamas Bartfai

Science 2016 09;353(6306):1363-1364

Department of Neurochemistry, Stockholm University, 106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aai8465DOI Listing
September 2016

G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells.

Oncotarget 2016 Mar;7(11):12823-39

The National Center for Drug Screening and The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai 201203, China.

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http://dx.doi.org/10.18632/oncotarget.7313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914324PMC
March 2016

Single-cell transcriptomics and functional target validation of brown adipocytes show their complex roles in metabolic homeostasis.

FASEB J 2016 Jan 24;30(1):81-92. Epub 2015 Aug 24.

*Department of Pharmacology, Department of Genomics and Computational Biology, and Department of Cell and Developmental Biology, Perelman School of Medicine, and Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA; and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA

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http://dx.doi.org/10.1096/fj.15-273797DOI Listing
January 2016

Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation.

Genome Biol 2015 Jun 9;16:122. Epub 2015 Jun 9.

Department of Biology, School of Arts and Sciences, University of Pennsylvania, 301A/B Lynch Laboratory, 433 S University Avenue, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s13059-015-0683-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480509PMC
June 2015

The promise of single-cell sequencing.

Nat Methods 2014 Jan;11(1):25-7

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http://dx.doi.org/10.1038/nmeth.2769DOI Listing
January 2014

Novel systemically active galanin receptor 2 ligands in depression-like behavior.

J Neurochem 2013 Oct 31;127(1):114-23. Epub 2013 May 31.

Institute of Technology, University of Tartu, Tartu, Estonia; Department of Neurochemistry, Arrhenius Laboratories for Natural Sciences, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/jnc.12274DOI Listing
October 2013

Positive allosteric modulators to peptide GPCRs: a promising class of drugs.

Acta Pharmacol Sin 2013 Jul 29;34(7):880-5. Epub 2013 Apr 29.

Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1038/aps.2013.20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002610PMC
July 2013

High-throughput FRET assay yields allosteric SERCA activators.

J Biomol Screen 2013 Jan 24;18(1):97-107. Epub 2012 Aug 24.

Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1177/1087057112456878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721969PMC
January 2013

Galanin receptors and ligands.

Front Endocrinol (Lausanne) 2012 7;3:146. Epub 2012 Dec 7.

Department of Neurochemistry, Arrhenius Laboratories for Natural Science, Stockholm University Stockholm, Sweden.

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http://dx.doi.org/10.3389/fendo.2012.00146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516677PMC
December 2012

Neuropeptides and neuropeptide receptors: drug targets, and peptide and non-peptide ligands: a tribute to Prof. Dieter Seebach.

Chem Biodivers 2012 Nov;9(11):2367-87

Department of Pharmacology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1002/cbdv.201200288DOI Listing
November 2012

Molecules affecting hypothalamic control of core body temperature in response to calorie intake.

Front Genet 2012 5;3:184. Epub 2012 Oct 5.

Department of Chemical Physiology, The Scripps Research Institute La Jolla, CA, USA.

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http://dx.doi.org/10.3389/fgene.2012.00184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466567PMC
October 2012

Receptor subtype-dependent galanin actions on gamma-aminobutyric acidergic neurotransmission and ethanol responses in the central amygdala.

Addict Biol 2012 Jul 28;17(4):694-705. Epub 2011 Sep 28.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00360.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252398PMC
July 2012

Drug targets: single-cell transcriptomics hastens unbiased discovery.

Trends Pharmacol Sci 2012 Jan 25;33(1):9-16. Epub 2011 Oct 25.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10 550N. Torrey Pines Road, SR307, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1016/j.tips.2011.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259260PMC
January 2012

Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2.

Bioorg Med Chem Lett 2011 Dec 25;21(23):7210-5. Epub 2011 Sep 25.

Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, United States.

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http://dx.doi.org/10.1016/j.bmcl.2011.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278223PMC
December 2011

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures.

Brain Behav Immun 2011 Oct 5;25(7):1281-9. Epub 2011 Apr 5.

Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Via G. La Masa 19, 20156 Milano, Italy.

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http://dx.doi.org/10.1016/j.bbi.2011.03.018DOI Listing
October 2011

Therapeutic potential of new antiinflammatory drugs.

Epilepsia 2011 Oct;52 Suppl 8:67-9

Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Via G. La Masa 19, Milan, Italy.

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http://dx.doi.org/10.1111/j.1528-1167.2011.03242.xDOI Listing
October 2011

Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors.

J Biol Chem 2011 Apr 17;286(17):14983-90. Epub 2011 Feb 17.

Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1074/jbc.M110.188540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3083203PMC
April 2011

Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response Signaling asymmetry and an extension of chemical neuroanatomy.

Pharmacol Ther 2011 Mar 21;129(3):241-59. Epub 2010 Oct 21.

Department of Pharmacology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.pharmthera.2010.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065349PMC
March 2011

Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.

Cytokine 2011 Mar 21;53(3):311-9. Epub 2010 Dec 21.

The Harold L. Dorris Neurological Research Institute, Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104346661000767
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http://dx.doi.org/10.1016/j.cyto.2010.11.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033975PMC
March 2011

Morphological and behavioral changes induced by transgenic overexpression of interleukin-1ra in the brain.

J Neurosci Res 2011 Feb 8;89(2):142-52. Epub 2010 Dec 8.

Department of Neurobiology, Care Sciences and Society, Division of Neurodegeneration, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/jnr.22534DOI Listing
February 2011

Pharma TARP: a troubled asset relief program for novel, abandoned projects in the pharmaceutical industry.

ScientificWorldJournal 2011 Feb 14;11:454-7. Epub 2011 Feb 14.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1100/tsw.2011.61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720016PMC
February 2011

The role of inflammation in epilepsy.

Nat Rev Neurol 2011 Jan 7;7(1):31-40. Epub 2010 Dec 7.

Department of Neuroscience, Mario Negri Institute for Pharmacological Research, Via Giuseppe La Masa 19, 20156 Milan, Italy.

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http://www.nature.com/articles/nrneurol.2010.178
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http://dx.doi.org/10.1038/nrneurol.2010.178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378051PMC
January 2011

Why is the New York Times writing so much about Alzheimer's disease therapies?

Authors:
Tamas Bartfai

ScientificWorldJournal 2010 Sep 14;10:1886-9. Epub 2010 Sep 14.

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http://dx.doi.org/10.1100/tsw.2010.185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763718PMC
September 2010

GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.

Proc Natl Acad Sci U S A 2010 Aug 26;107(34):15229-34. Epub 2010 Jul 26.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.1008986107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930524PMC
August 2010

Fever.

ScientificWorldJournal 2010 Mar 16;10:490-503. Epub 2010 Mar 16.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA, USA.

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http://www.hindawi.com/journals/tswj/2010/636738/abs/
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http://dx.doi.org/10.1100/tsw.2010.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850202PMC
March 2010

Metabolic characterization of a mouse deficient in all known leptin receptor isoforms.

Cell Mol Neurobiol 2010 Jan 7;30(1):23-33. Epub 2009 Jul 7.

Molecular and Integrative Neurosciences Department, The Harold L. Dorris Neurological Research Institute, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/s10571-009-9427-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813927PMC
January 2010

Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice.

Naunyn Schmiedebergs Arch Pharmacol 2009 Apr 22;379(4):417-20. Epub 2009 Jan 22.

The Harold L. Dorris Neurological Research Institute, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, SR-307, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/s00210-009-0394-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725758PMC
April 2009

Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain.

J Neuroimmunol 2009 Mar 10;208(1-2):46-53. Epub 2009 Feb 10.

Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jneuroim.2009.01.010DOI Listing
March 2009

A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta.

Brain 2008 Dec 24;131(Pt 12):3256-65. Epub 2008 Oct 24.

Department of Neuroscience, Laboratory of Experimental Neurology, Mario Negri Institute for Pharmacological Research, Milan, Italy.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/awn271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724908PMC
December 2008

Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance.

Swiss Med Wkly 2008 Nov;138(45-46):665-73

The Harold L. Dorris Neurological Research Institute, and Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org//aop/smw-aop12276DOI Listing
November 2008

Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests.

Neuropeptides 2008 Aug 12;42(4):387-97. Epub 2008 Jun 12.

The Harold L Dorris Neurological Institute, Department of Molecular and Integrative Neurosciences, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.npep.2008.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399724PMC
August 2008

Choices in neuroscience careers.

Nat Rev Neurosci 2008 05;9(5):401-5

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http://dx.doi.org/10.1038/nrn2386DOI Listing
May 2008

Galanin alters GABAergic neurotransmission in the dorsal raphe nucleus.

Neurochem Res 2008 Feb 1;33(2):285-91. Epub 2007 Nov 1.

Molecular and Integrative Neurosciences Department, The Harold L Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1007/s11064-007-9524-5DOI Listing
February 2008

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity.

Proc Natl Acad Sci U S A 2008 Feb 12;105(7):2681-6. Epub 2008 Feb 12.

Division of Rheumatology Research, W. M. Keck Autoimmune Disease Center, and Department of Molecular and Experimental Medicine, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0712197105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268196PMC
February 2008

Blunted neurogenesis and gliosis due to transgenic overexpression of human soluble IL-1ra in the mouse.

Eur J Neurosci 2008 Feb;27(3):549-58

Department of Neurobiology, Care Sciences and Society, Novum, floor 5, Division of Neurodegeneration and Neuroinflammation, Karolinska Institutet, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1460-9568.2008.06050.xDOI Listing
February 2008

Molecular characterization of the ligand binding site of the human galanin receptor type 2, identifying subtype selective interactions.

J Neurochem 2007 Dec 22;103(5):1774-84. Epub 2007 Oct 22.

Department of Neurochemistry, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04959.xDOI Listing
December 2007

Interleukin-1 system in CNS stress: seizures, fever, and neurotrauma.

Ann N Y Acad Sci 2007 Oct 26;1113:173-7. Epub 2007 Jul 26.

Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, USA.

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http://doi.wiley.com/10.1196/annals.1391.022
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http://dx.doi.org/10.1196/annals.1391.022DOI Listing
October 2007

The brain galanin receptors: targets for novel antidepressant drugs.

CNS Neurol Disord Drug Targets 2007 Jun;6(3):183-92

Molecular and Integrative Neuroscience Department (MIND) and The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Rd (SR-307), La Jolla, CA 92037, USA.

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http://dx.doi.org/10.2174/187152707780619335DOI Listing
June 2007

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency.

Proc Natl Acad Sci U S A 2007 Jun 19;104(26):11097-102. Epub 2007 Jun 19.

Harold L. Dorris Neurological Research Institute, Committee on the Neurobiology of Addictive Disorders, and Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://www.pnas.org/content/104/26/11097.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.0611523104
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http://dx.doi.org/10.1073/pnas.0611523104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904154PMC
June 2007

It all happens between Toll receptors and caspase 1.

Proc Natl Acad Sci U S A 2007 May 1;104(19):7733-4. Epub 2007 May 1.

The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0702505104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876513PMC
May 2007

Adipose tissue as a modulator of clinical inflammation: does obesity reduce the prevalence of rheumatoid arthritis?

J Rheumatol 2007 Mar 15;34(3):488-92. Epub 2007 Feb 15.

Department of Molecular and Integrative Neurosciences and Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, USA.

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March 2007

Night eating and obesity in the EP3R-deficient mouse.

Proc Natl Acad Sci U S A 2007 Feb 16;104(8):3009-14. Epub 2007 Feb 16.

The Harold L. Dorris Neurological Research Institute and Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0611209104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1800735PMC
February 2007

IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons.

J Neurochem 2006 Sep 12;98(5):1379-89. Epub 2006 Jun 12.

The Harold L. Dorris Neurological Research Institute and Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03951.xDOI Listing
September 2006

A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests.

Neurosci Lett 2006 Sep 18;405(1-2):111-5. Epub 2006 Jul 18.

Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, La Jolla, CA, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400600620
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http://dx.doi.org/10.1016/j.neulet.2006.06.033DOI Listing
September 2006

From lab bench to Wall Street.

Authors:
Tamas Bartfai

FASEB J 2006 Aug;20(10):1578-80

Department of Molecular and Integrative Neurosciences, The Harold L. Dorris Neurological Research Institute, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1096/fj.06-0802ufmDOI Listing
August 2006

Impaired gene and protein expression of exocytotic soluble N-ethylmaleimide attachment protein receptor complex proteins in pancreatic islets of type 2 diabetic patients.

Diabetes 2006 Feb;55(2):435-40

Department of Molecular Medicine and Surgery, Endocrine and Diabetes Unit, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.2337/diabetes.55.02.06.db04-1575DOI Listing
February 2006

A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons.

J Neurosci 2006 Feb;26(5):1604-15

The Harold L. Dorris Neurological Research Center, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, La Jolla, California 92037, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4722-05.2
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http://dx.doi.org/10.1523/JNEUROSCI.4722-05.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675509PMC
February 2006

Ceramide mediates the rapid phase of febrile response to IL-1beta.

Proc Natl Acad Sci U S A 2006 Feb 13;103(8):2904-8. Epub 2006 Feb 13.

Harold L. Dorris Neurological Research Center, Molecular and Integrative Neurosciences Department, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0510960103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413811PMC
February 2006

TLR2 is required for the altered transcription of p75NGF receptors in gram positive infection.

Neurochem Res 2006 Feb 3;31(2):297-301. Epub 2006 Mar 3.

The Harold L. Dorris Neurological Research Center, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1007/s11064-005-9020-8DOI Listing
February 2006

Galanin and its receptors in neurological disorders.

Neuromolecular Med 2005 ;7(1-2):157-80

Department of Neurochemistry and Neurotoxicology, Stockholm University, S-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1385/NMM:7:1-2:157DOI Listing
December 2005

Homodimerization and internalization of galanin type 1 receptor in living CHO cells.

Neuropeptides 2005 Dec 20;39(6):535-46. Epub 2005 Oct 20.

Department of Neuropharmacology, Harold L. Dorris Neurological Research Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.npep.2005.09.001DOI Listing
December 2005

Multiple interaction sites of galnon trigger its biological effects.

Neuropeptides 2005 Dec 16;39(6):547-58. Epub 2005 Nov 16.

Department of Neurochemistry, Stockholm University, Sweden.

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http://dx.doi.org/10.1016/j.npep.2005.09.005DOI Listing
December 2005

Galanin receptor ligands.

Neuropeptides 2005 Jun 1;39(3):143-6. Epub 2005 Feb 1.

Department of Neuropharmacology, The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.npep.2004.12.012DOI Listing
June 2005

Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity.

Neuropeptides 2005 Jun 26;39(3):147-52. Epub 2005 Jan 26.

Department of Neuropharmacology, The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.npep.2004.12.011DOI Listing
June 2005

Galnon--a low-molecular weight ligand of the galanin receptors.

Neuropeptides 2005 Jun 2;39(3):161-3. Epub 2005 Feb 2.

Department of Neurochemistry and Neurotoxicology, Stockholm University, Svante Arrhenius väg 21A, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.npep.2004.12.019DOI Listing
June 2005

Galanin (2-11) binds to GalR3 in transfected cell lines: limitations for pharmacological definition of receptor subtypes.

Neuropeptides 2005 Jun 1;39(3):165-7. Epub 2005 Feb 1.

Department of Neuropharmacology, The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.npep.2004.12.013DOI Listing
June 2005

Important pharmacophores for binding to galanin receptor 2.

Neuropeptides 2005 Jun 16;39(3):169-71. Epub 2005 Feb 16.

Department of Neurochemistry and Neurotoxicology, Stockholm University, Svante Arrheniusv. 21A, 106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.npep.2004.12.029DOI Listing
June 2005

Age-related impairments of synaptic plasticity in the lateral perforant path input to the dentate gyrus of galanin overexpressing mice.

Neuropeptides 2005 Jun 7;39(3):259-67. Epub 2005 Apr 7.

Department of Neuroscience, Karolinska Institutet, S-171 71, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.npep.2005.02.005DOI Listing
June 2005

Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoamines.

Brain Behav Immun 2005 May;19(3):223-34

Division of Experimental Geriatrics, Neurotec Department, Karolinska Institutet, Novum, KFC, 4th floor, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbi.2004.07.006DOI Listing
May 2005

Effects of galnon, a non-peptide galanin-receptor agonist, on insulin release from rat pancreatic islets.

Biochem Biophys Res Commun 2005 Mar;328(1):213-20

Department of Molecular Medicine, Karolinska Institutet and Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2004.12.150DOI Listing
March 2005

Neuropeptide expression in rats exposed to chronic mild stresses.

Psychopharmacology (Berl) 2005 Mar 30;178(2-3):115-24. Epub 2004 Oct 30.

Department of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://link.springer.com/10.1007/s00213-004-2015-3
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http://dx.doi.org/10.1007/s00213-004-2015-3DOI Listing
March 2005

Evaluation of transportan 10 in PEI mediated plasmid delivery assay.

J Control Release 2005 Mar 26;103(2):511-23. Epub 2005 Jan 26.

Department of Neurochemistry and Neurotoxicology, Stockholm University, S-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jconrel.2004.12.006DOI Listing
March 2005

Interleukin-1beta contributes to the generation of experimental febrile seizures.

Ann Neurol 2005 Jan;57(1):152-5

Department of Anatomy & Neurobiology, University of California at Irvine, Medical Science I, ZOT:4475, Irvine, CA 92697-4475, USA.

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http://doi.wiley.com/10.1002/ana.20358
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http://dx.doi.org/10.1002/ana.20358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909879PMC
January 2005

A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus.

Proc Natl Acad Sci U S A 2005 Jan 12;102(3):874-9. Epub 2005 Jan 12.

Department of Neuropharmacology and The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0408891102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545581PMC
January 2005

Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity.

Biochem Biophys Res Commun 2004 Dec;325(2):574-9

Group of Transcriptional Networks, Unit of Functional Genomics, Center for Genomics and Bioinformatics (CGB), Karolinska Institute, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2004.10.078DOI Listing
December 2004

Synthesis of galmic: a nonpeptide galanin receptor agonist.

Proc Natl Acad Sci U S A 2004 Nov 19;101(48):16727-32. Epub 2004 Nov 19.

Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0407543101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC534730PMC
November 2004

Targeting of antisense PNA oligomers to human galanin receptor type 1 mRNA.

Neuropeptides 2004 Oct;38(5):316-24

Department of Neurochemistry and Neurotoxicology, Arrhenius Laboratories, Stockholm University, Svante Arrheniusvag. 21A, S-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.npep.2004.06.005DOI Listing
October 2004

Effects of chronic overexpression of interleukin-1 receptor antagonist in a model of permanent focal cerebral ischemia in mouse.

Acta Neuropathol 2004 Jul 8;108(1):69-80. Epub 2004 May 8.

Neurotec Department, Division of Experimental Geriatrics, Karolinska Institutet, Novum, Karolinska University Hospital Huddinge, 141 86, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00401-004-0868-5DOI Listing
July 2004

Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests.

Proc Natl Acad Sci U S A 2004 Jul 6;101(28):10470-5. Epub 2004 Jul 6.

Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0403802101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC478593PMC
July 2004

Galanin type 2 receptors regulate neuronal survival, susceptibility to seizures and seizure-induced neurogenesis in the dentate gyrus.

Eur J Neurosci 2004 Jun;19(12):3235-44

West Los Angeles VA Medical Center, and Department of Neurology, D. Geffen Medical School, UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/j.0953-816X.2004.03449.xDOI Listing
June 2004

Cytokines and fever.

Front Biosci 2004 May 1;9:1433-49. Epub 2004 May 1.

Harold L. Dorris Neurological Research Center, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.2741/1341DOI Listing
May 2004

High frequency of TNF alleles -238A and -376A in individuals from northern Sardinia.

Cytokine 2004 May;26(4):149-54

The Harold L. Dorris Neurological Research Center, Department of Neuropharmacology, The Scripps Research Institute, 10550 North Torrey Pines Road, SR307, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.cyto.2004.02.006DOI Listing
May 2004

Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5.

J Pharmacol Exp Ther 2004 Feb 10;308(2):574-82. Epub 2003 Nov 10.

Department of Anesthesiology, University of California, San Diego, La Jolla, CA 92103-0818, USA.

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http://dx.doi.org/10.1124/jpet.103.058289DOI Listing
February 2004

Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition.

Proc Natl Acad Sci U S A 2004 Feb;101(8):2590-5

Department of Neuropharmacology, The Harold L Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC356994PMC
http://dx.doi.org/10.1073/pnas.0308718101DOI Listing
February 2004

Regulation of feeding by galnon.

Neuropeptides 2004 Feb;38(1):55-61

Department of Physiology, Tartu University, Ravila 19, Tartu 50 411, Estonia.

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http://dx.doi.org/10.1016/j.npep.2004.01.001DOI Listing
February 2004

Systemic galnon, a low-molecular weight galanin receptor agonist, reduces heat hyperalgesia in rats with nerve injury.

Eur J Pharmacol 2003 Dec;482(1-3):133-7

Department of Medical Laboratory Sciences and Technology, Division of Clinical Neurophysiology, Huddinge University Hospital, Karolinska Institutet, S-141 86 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ejphar.2003.09.018DOI Listing
December 2003

Neuropeptides: opportunities for drug discovery.

Lancet Neurol 2003 Aug;2(8):463-72

Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/s1474-4422(03)00482-4DOI Listing
August 2003

The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal.

Proc Natl Acad Sci U S A 2003 Jul 9;100(15):9028-33. Epub 2003 Jul 9.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06508, USA.

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http://dx.doi.org/10.1073/pnas.1533224100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166432PMC
July 2003

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.

Proc Natl Acad Sci U S A 2003 Jun 10;100(13):7971-6. Epub 2003 Jun 10.

Department of Neuropharmacology, The Harold L. Dorris Neurological Research Center, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0932746100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC164697PMC
June 2003

Synthesis of cell-penetrating peptide-PNA constructs.

Methods Mol Biol 2002 ;208:225-36

Estonian Biocentre, Tartu, Estonia.

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http://dx.doi.org/10.1385/1-59259-290-2:225DOI Listing
March 2003

Galanin overexpressing transgenic mice.

Neuropeptides 2002 Apr-Jun;36(2-3):145-56

Section on Behavioral Genomics, National Institute of Mental Health, Bethesda, MD 20815, USA.

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http://dx.doi.org/10.1054/npep.2002.0891DOI Listing
November 2002