Takuya Ohtani

Takuya Ohtani

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Takuya Ohtani

Takuya Ohtani

Publications by authors named "Takuya Ohtani"

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11Publications

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PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185 Tumor Immunotherapy.

Front Immunol 2019 8;10:174. Epub 2019 Feb 8.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375878PMC
February 2020

Exploration of T-Cell Diversity Using Mass Cytometry.

Methods Mol Biol 2020 ;2111:1-20

Department of Systems Pharmacology and Translational Therapeutics, Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

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http://dx.doi.org/10.1007/978-1-0716-0266-9_1DOI Listing
January 2020

Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage.

J Allergy Clin Immunol 2019 Dec 22;144(6):1660-1673. Epub 2019 Aug 22.

Division of Immunology and Allergy, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900457PMC
December 2019

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.

Immunity 2018 05;48(5):1029-1045.e5

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010198PMC
May 2018

Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns.

J Immunol Methods 2018 02 19;453:3-10. Epub 2017 Mar 19.

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2017.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605401PMC
February 2018

Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.

PLoS One 2016 18;11(5):e0155408. Epub 2016 May 18.

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Institute of Medicine and Engineering, Institute for Immunology, Center for Personalized Diagnostics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155408PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871414PMC
July 2017

Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation.

J Biol Chem 2015 Aug 18;290(33):20211-20. Epub 2015 May 18.

From the Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104,

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http://dx.doi.org/10.1074/jbc.M115.638221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536430PMC
August 2015

Notch regulation of early thymocyte development.

Semin Immunol 2010 Oct 13;22(5):261-9. Epub 2010 Jul 13.

The Department of Pathology & Laboratory Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.smim.2010.04.015DOI Listing
October 2010

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

Genes Dev 2009 Jul;23(14):1665-76

Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://genesdev.cshlp.org/content/23/14/1665.full.pdf
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http://genesdev.cshlp.org/cgi/doi/10.1101/gad.1793709
Publisher Site
http://dx.doi.org/10.1101/gad.1793709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714710PMC
July 2009