Takuya Awata

Takuya Awata

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Takuya Awata

Publications by authors named "Takuya Awata"

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Clinical considerations for use of insulin degludec/insulin aspart in Japanese patients.

Expert Opin Biol Ther 2018 01 20;18(1):77-85. Epub 2017 Oct 20.

d Medical & Scientific Affairs Department , Novo Nordisk Pharma Ltd ., Tokyo , Japan.

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http://dx.doi.org/10.1080/14712598.2018.1389888DOI Listing
January 2018

Feminizing Adrenocortical Carcinoma with Distinct Histopathological Findings.

Intern Med 2016;55(22):3301-3307. Epub 2016 Nov 15.

Department of Endocrinology and Diabetes, Saitama Medical University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.55.5912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173498PMC
February 2017

Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine.

PLoS One 2016 29;11(3):e0152207. Epub 2016 Mar 29.

Department of Biochemistry, Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152207PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811413PMC
August 2016

The efficacy of vildagliptin concomitant with insulin therapy in type 2 diabetic subjects.

J Clin Med Res 2015 May 1;7(5):303-7. Epub 2015 Mar 1.

Third Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Kyorin University School of Medicine, 6-20-2, Shinkawa, Mitaka, Tokyo, Japan.

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http://dx.doi.org/10.14740/jocmr2057wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356089PMC
May 2015

Identification of two nickel ion-induced genes, NCI16 and PcGST1, in Paramecium caudatum.

Eukaryot Cell 2014 Sep 7;13(9):1181-90. Epub 2014 Jul 7.

Department of Diabetes and Endocrinology, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1128/EC.00112-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187627PMC
September 2014

Mediobasal hypothalamic PTEN modulates hepatic insulin resistance independently of food intake in rats.

Am J Physiol Endocrinol Metab 2014 Jul 13;307(1):E47-60. Epub 2014 May 13.

Department of Endocrinology and Diabetes, School of Medicine, Saitama Medical University, Moroyama, Saitama, Japan;

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http://dx.doi.org/10.1152/ajpendo.00361.2013DOI Listing
July 2014

Tumor-induced osteomalacia: benign tumor recurrence after two surgical resections at two different medical institutions.

Endocr Pract 2013 Jul-Aug;19(4):e97-101

Department of Endocrinology and Diabetes, Saitama Medical University, Saitama 350-0495, Japan.

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http://journals.aace.com/doi/abs/10.4158/EP13042.CR
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http://dx.doi.org/10.4158/EP13042.CRDOI Listing
March 2014

Clostridium butyricum MIYAIRI 588 improves high-fat diet-induced non-alcoholic fatty liver disease in rats.

Dig Dis Sci 2013 Dec 29;58(12):3534-44. Epub 2013 Oct 29.

Department of Biochemistry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Iruma, Saitama, 350-0495, Japan,

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http://link.springer.com/10.1007/s10620-013-2879-3
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http://dx.doi.org/10.1007/s10620-013-2879-3DOI Listing
December 2013

A low-frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes.

Biochem Biophys Res Commun 2013 Aug 13;437(4):521-5. Epub 2013 Jul 13.

Division of Endocrinology and Diabetes, Faculty of Medicine, Saitama Medical University, Moroyama-machi, Iruma-gun, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2013.06.102DOI Listing
August 2013

Hypoglycemic effects of colestimide on type 2 diabetic patients with obesity.

Endocr J 2012 7;59(3):239-46. Epub 2012 Jan 7.

Department of Endocrinology and Diabetes, School of Medicine, Saitama Medical University, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1507/endocrj.ej11-0378DOI Listing
July 2012

[Acute-onset typical type 1 diabetes mellitus].

Authors:
Takuya Awata

Nihon Rinsho 2012 May;70 Suppl 3:358-64

Department of Endocrinology and Diabetes, Faculty of Medicine, Saitama Medical University.

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May 2012

Type 1 diabetes and interferon therapy: a nationwide survey in Japan.

Diabetes Care 2011 Sep 20;34(9):2084-9. Epub 2011 Jul 20.

Department of Metabolism/Diabetes and Clinical Nutrition, Nagasaki University Hospital, Nagasaki, Japan.

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http://dx.doi.org/10.2337/dc10-2274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161293PMC
September 2011

Associations of cigarette smoking but not serum fatty acids with age-related macular degeneration in a Japanese population.

Ophthalmology 2011 Jun 22;118(6):1082-8. Epub 2011 Apr 22.

Department of Ophthalmology, Saitama Medical University, Iruma, Saitama, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2010.10.012DOI Listing
June 2011

Free immunoglobulin light chain: its biology and implications in diseases.

Clin Chim Acta 2011 May 15;412(11-12):843-9. Epub 2011 Mar 15.

Department of Biochemistry, Faculty of Medicine, Saitama Medical University, Saitama, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S000989811100136
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http://dx.doi.org/10.1016/j.cca.2011.03.007DOI Listing
May 2011

Effects of telmisartan on insulin resistance in Japanese type 2 diabetic patients.

Intern Med 2010 1;49(17):1843-7. Epub 2010 Sep 1.

Department of Endocrinology and Diabetes, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.2169/internalmedicine.49.3189DOI Listing
January 2011

Vascular endothelial growth factor gene polymorphisms in susceptibility to coronary artery disease.

Authors:
Takuya Awata

Am J Hypertens 2010 Sep;23(9):938-9

Department of Endocrinology and Diabetes, Saitama Medical University, Iruma-gun, Japan.

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http://dx.doi.org/10.1038/ajh.2010.151DOI Listing
September 2010

Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL?

Recent Pat Cardiovasc Drug Discov 2010 Jun;5(2):143-52

Division of Endcrinology and Diabetics, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.2174/157489010791515386DOI Listing
June 2010

Activating effect of momordin, extract of bitter melon (Momordica Charantia L.), on the promoter of human PPARdelta.

J Atheroscler Thromb 2009 22;16(6):888-92. Epub 2009 Dec 22.

Department of Diabetes and Endocrinology, Saitama Medical University, Japan.

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http://dx.doi.org/10.5551/jat.2790DOI Listing
April 2010

A promoter in the novel exon of hPPARgamma directs the circadian expression of PPARgamma.

J Atheroscler Thromb 2010 Feb 21;17(1):73-83. Epub 2010 Jan 21.

Department of Diabetes and Endocrinology, Saitama Medical University, Saitama 350-0495, Japan.

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http://dx.doi.org/10.5551/jat.2410DOI Listing
February 2010

Dopamine D1-like receptor antagonist, SCH23390, exhibits a preventive effect on diabetes mellitus that occurs naturally in NOD mice.

Biochem Biophys Res Commun 2009 Jun 14;383(4):460-3. Epub 2009 Apr 14.

Department of Allergy and Immunology, Saitama Medical University, Saitama, 38 Morohongo, Moroyama, Saitama 350-0495, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0900723
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http://dx.doi.org/10.1016/j.bbrc.2009.04.034DOI Listing
June 2009

Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.

J Clin Endocrinol Metab 2009 Mar 23;94(3):947-52. Epub 2008 Dec 23.

Department of Metabolism/Diabetes and Clinical Nutrition, Nagasaki University Hospital of Medicine and Dentistry, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

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http://dx.doi.org/10.1210/jc.2008-1596DOI Listing
March 2009

Adiponectin upregulates ferritin heavy chain in skeletal muscle cells.

Diabetes 2009 Jan 17;58(1):61-70. Epub 2008 Oct 17.

Department of Endocrinology and Diabetes, School of Medicine, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.2337/db07-0690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606894PMC
January 2009

Association of type 1 diabetes with two Loci on 12q13 and 16p13 and the influence coexisting thyroid autoimmunity in Japanese.

J Clin Endocrinol Metab 2009 Jan 21;94(1):231-5. Epub 2008 Oct 21.

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1210/jc.2008-0718DOI Listing
January 2009

Involvement of low adiponectin levels in impaired glucose tolerance.

Metabolism 2008 Oct;57(10):1350-4

Department of Endocrinology and Diabetes, School of Medicine, Saitama Medical University, Moroyama, Iruma-gun, Saitama, 350-0495, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S002604950800187
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http://dx.doi.org/10.1016/j.metabol.2008.05.001DOI Listing
October 2008

Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese.

J Autoimmun 2008 Jun 23;30(4):207-11. Epub 2007 Oct 23.

Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1016/j.jaut.2007.09.002DOI Listing
June 2008

SH3 domain of the phosphatidylinositol 3-kinase regulatory subunit is responsible for the formation of a sequestration complex with insulin receptor substrate-1.

Biochem Biophys Res Commun 2008 Jan 6;365(3):433-8. Epub 2007 Nov 6.

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical University, Morohongo 38, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.10.187DOI Listing
January 2008

[Adiponectin receptor regulation in diabetic states].

Nihon Rinsho 2007 Nov;65(11):2125-30

Division of Endocrinology and Diabetes, Department of Internal Medicine, Saitama Medical University.

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November 2007

Promoter polymorphisms of the pigment epithelium-derived factor gene are associated with diabetic retinopathy.

Biochem Biophys Res Commun 2007 Sep 16;361(2):421-6. Epub 2007 Jul 16.

Division of RI Laboratory, Biomedical Research Center, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.07.025DOI Listing
September 2007

Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.

J Hum Genet 2007 14;52(7):636-641. Epub 2007 Jun 14.

Division of Gene Regulation and Signal Transduction, Saitama Medical University, Faculty of Medicine, Iruma, Saitama, Japan.

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http://link.springer.com/content/pdf/10.1007/s10038-007-0162
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http://www.nature.com/doifinder/10.1007/s10038-007-0162-1
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http://dx.doi.org/10.1007/s10038-007-0162-1DOI Listing
August 2007

Insulin gene/IDDM2 locus in Japanese type 1 diabetes: contribution of class I alleles and influence of class I subdivision in susceptibility to type 1 diabetes.

J Clin Endocrinol Metab 2007 May 6;92(5):1791-5. Epub 2007 Mar 6.

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1210/jc.2006-2242DOI Listing
May 2007

LKB1, an upstream AMPK kinase, regulates glucose and lipid metabolism in cultured liver and muscle cells.

Biochem Biophys Res Commun 2006 Dec 18;351(3):595-601. Epub 2006 Oct 18.

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical School, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.10.056DOI Listing
December 2006

Association of SUMO4, as a candidate gene for IDDM5, with susceptibility to type 1 diabetes in Asian populations.

Ann N Y Acad Sci 2006 Oct;1079:41-6

Department of Endocrinology, Diabetes and Metabolism, Kinki University School of Medicine, 377-2 Ohno-higashi, Sayama-shi, Osaka 589-8511, Japan.

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http://dx.doi.org/10.1196/annals.1375.006DOI Listing
October 2006

Evidence for the role of small ubiquitin-like modifier 4 as a general autoimmunity locus in the Japanese population.

J Clin Endocrinol Metab 2006 Aug 30;91(8):3138-43. Epub 2006 May 30.

Department of Metabolism/Diabetes and Clinical Nutrition, Nagasaki University Hospital of Medicine and Dentistry, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.

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http://dx.doi.org/10.1210/jc.2006-0206DOI Listing
August 2006

Acarbose improves fibrinolytic activity in patients with impaired glucose tolerance.

Metabolism 2006 Jul;55(7):935-9

Department of Biochemistry, Saitama Medical School, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.metabol.2006.02.023DOI Listing
July 2006

Acarbose ameliorates atherogenecity of low-density lipoprotein in patients with impaired glucose tolerance.

Metabolism 2006 Jul;55(7):946-52

Department of Diabetic and Endocrinology, Saitama Medical School, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S002604950600100
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http://dx.doi.org/10.1016/j.metabol.2006.03.002DOI Listing
July 2006

Genetic heterogeneity in association of the SUMO4 M55V variant with susceptibility to type 1 diabetes.

Diabetes 2005 Dec;54(12):3582-6

Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, Japan.

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http://dx.doi.org/10.2337/diabetes.54.12.3582DOI Listing
December 2005

Identification of a novel WFS1 mutation (AFF344-345ins) in Japanese patients with Wolfram syndrome.

Diabetes Res Clin Pract 2005 Aug 24;69(2):136-41. Epub 2005 Feb 24.

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical School, Morohongo 38, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.diabres.2005.01.002DOI Listing
August 2005

Efficacy of glimepiride in Japanese type 2 diabetic subjects.

Diabetes Res Clin Pract 2005 Jun 19;68(3):250-7. Epub 2004 Nov 19.

Division of Endocrinology and Diabetes, Department of Internal Medicine, Saitama Medical School, 38 Morohongo, Iruma-gun, Saitama-ken 350-0495, Japan.

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http://dx.doi.org/10.1016/j.diabres.2004.10.002DOI Listing
June 2005

Regulation of adiponectin receptor gene expression in diabetic mice.

Am J Physiol Endocrinol Metab 2005 May 21;288(5):E876-82. Epub 2004 Dec 21.

Division of Endocrinology and Diabetes, Deptartment of Internal Medicine, Saitama Medical School, Saitama 350-0495, Japan.

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http://ajpendo.physiology.org/content/ajpendo/288/5/E876.ful
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http://ajpendo.physiology.org/content/ajpendo/early/2004/12/
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http://ajpendo.physiology.org/cgi/doi/10.1152/ajpendo.00118.
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http://dx.doi.org/10.1152/ajpendo.00118.2004DOI Listing
May 2005

Glimepiride enhances intrinsic peroxisome proliferator-activated receptor-gamma activity in 3T3-L1 adipocytes.

Biochem Biophys Res Commun 2005 Mar;328(2):484-90

Division of Endocrinology and Diabetes, Department of Medicine, Saitama Medical School, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.12.190DOI Listing
March 2005

Pro12Ala substitution in peroxisome proliferator-activated receptor gamma 2 is associated with low adiponectin concentrations in young Japanese men.

Metabolism 2004 Dec;53(12):1548-51

Division of Endocrinoloy and Diabetes, Department of Medicine, Saitama Medical School, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.metabol.2004.06.022DOI Listing
December 2004

ANGPTL3 is increased in both insulin-deficient and -resistant diabetic states.

Biochem Biophys Res Commun 2004 May;317(4):1075-9

The Fourth Department of Internal Medicine, Saitama Medical School, Morohongo 38, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.151DOI Listing
May 2004

Apoptosis of endothelial cells may be mediated by genes of peroxisome proliferator-activated receptor gamma 1 (PPARgamma 1) and PPARalpha genes.

J Atheroscler Thromb 2003 ;10(2):99-108

Fourth Department of Medicine, Saitama Medical School, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.5551/jat.10.99DOI Listing
August 2003

Regulation of PPAR gamma transcriptional activity in 3T3-L1 adipocytes.

Biochem Biophys Res Commun 2003 Jan;300(2):429-36

Saitama Medical School Research Center for Genomic Medicine, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1016/s0006-291x(02)02860-7DOI Listing
January 2003

[HLA genes and prediction of type 1 diabetes].

Authors:
Takuya Awata

Nihon Rinsho 2002 Sep;60 Suppl 9:37-41

Fourth Department of Internal Medicine, Saitama Medical School.

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September 2002

Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

Biochem Biophys Res Commun 2002 Jan;290(1):131-9

Fourth Department of Internal Medicine, Saitama Medical School, 38 Morohongo, Moroyama, Iruma-gun, Saitama 350-0495, Japan.

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http://dx.doi.org/10.1006/bbrc.2001.6141DOI Listing
January 2002