Takuro Arimura

Takuro Arimura

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Takuro Arimura

Takuro Arimura

Publications by authors named "Takuro Arimura"

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Overexpression of heart-specific small subunit of myosin light chain phosphatase results in heart failure and conduction disturbance.

Am J Physiol Heart Circ Physiol 2018 06 16;314(6):H1192-H1202. Epub 2018 Feb 16.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University , Tokyo , Japan.

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http://dx.doi.org/10.1152/ajpheart.00696.2017DOI Listing
June 2018

Screening of sarcomere gene mutations in young athletes with abnormal findings in electrocardiography: identification of a MYH7 mutation and MYBPC3 mutations.

J Hum Genet 2015 Oct 16;60(10):641-5. Epub 2015 Jul 16.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2015.81DOI Listing
October 2015

Novel mutation in the α-myosin heavy chain gene is associated with sick sinus syndrome.

Circ Arrhythm Electrophysiol 2015 Apr 25;8(2):400-8. Epub 2015 Feb 25.

From the Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki (T.I., D.T.H., Y.T., N.M.); Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan (T.I., T.A., A.K.); Division of Pediatric Cardiology, University of Utah, Salt Lake City (C.J.J., C.B.A., S.M.B.); Cardiovascular Division, University of Tsukuba, Tsukuba (A.N.); Department of Heart Rhythm Management, Yokohama Rosai Hospital, Yokohama (A.N., S.K.); and Department of Veterinary Medicine, Kagoshima University, Kagoshima, Japan (T.A.).

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http://dx.doi.org/10.1161/CIRCEP.114.002534DOI Listing
April 2015

A novel de novo mutation of β-cardiac myosin heavy chain gene found in a twelve-year-old boy with hypertrophic cardiomyopathy.

J Genet 2014 Aug;93(2):557-60

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.

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http://search.proquest.com/openview/4c0f2358008a817a9cc3ea24
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http://dx.doi.org/10.1007/s12041-014-0414-8DOI Listing
August 2014

Dilated cardiomyopathy-associated FHOD3 variant impairs the ability to induce activation of transcription factor serum response factor.

Circ J 2013 1;77(12):2990-6. Epub 2013 Oct 1.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University.

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http://dx.doi.org/10.1253/circj.cj-13-0255DOI Listing
July 2014

A novel link of HLA locus to the regulation of immunity and infection: NFKBIL1 regulates alternative splicing of human immune-related genes and influenza virus M gene.

J Autoimmun 2013 Dec 14;47:25-33. Epub 2013 Aug 14.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jaut.2013.07.010DOI Listing
December 2013

Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5.

Circ J 2013 21;77(4):959-67. Epub 2012 Dec 21.

Division of Genetic Regulation, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1253/circj.cj-12-0995DOI Listing
September 2013

Impact of ANKRD1 mutations associated with hypertrophic cardiomyopathy on contraction parameters of engineered heart tissue.

Basic Res Cardiol 2013 May 10;108(3):349. Epub 2013 Apr 10.

Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00395-013-0349-xDOI Listing
May 2013

Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes.

Hum Mutat 2011 Dec 29;32(12):1481-91. Epub 2011 Sep 29.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1002/humu.21603DOI Listing
December 2011

Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1.

J Biol Chem 2010 Oct 27;285(44):33680-90. Epub 2010 Aug 27.

Department of Molecular Pathogenesis, Medical Research Institute, School of Biomedical Science, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1074/jbc.M110.122390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962466PMC
October 2010

A novel protein found in the I bands of myofibrils is produced by alternative splicing of the DLST gene.

Biochim Biophys Acta 2010 Jan 9;1800(1):31-9. Epub 2009 Oct 9.

Department of Biology and Health Science, Kanoya National Institute of Fitness and Sports, Kanoya, Kagoshima 891-2393, Japan.

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http://dx.doi.org/10.1016/j.bbagen.2009.10.003DOI Listing
January 2010

Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome.

J Biol Chem 2009 Dec 13;284(50):35122-33. Epub 2009 Oct 13.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1074/jbc.M109.017293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787373PMC
December 2009

Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease.

Hum Genet 2009 Oct 10;126(4):539-47. Epub 2009 Jun 10.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1007/s00439-009-0698-6DOI Listing
October 2009

Autophagic degradation of nuclear components in mammalian cells.

Autophagy 2009 Aug 30;5(6):795-804. Epub 2009 Aug 30.

Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.

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http://dx.doi.org/10.4161/auto.8901DOI Listing
August 2009

Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy.

Cardiovasc Res 2009 Jul 17;83(1):80-8. Epub 2009 Apr 17.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Bunkyo-Ku, Tokyo, Japan.

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http://dx.doi.org/10.1093/cvr/cvp119DOI Listing
July 2009

Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy.

J Am Coll Cardiol 2009 Jul;54(4):334-42

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jacc.2008.12.082DOI Listing
July 2009

Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy.

Circ J 2009 Jan 17;73(1):158-61. Epub 2008 Nov 17.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1253/circj.cj-08-0722DOI Listing
January 2009

Interaction of BMP10 with Tcap may modulate the course of hypertensive cardiac hypertrophy.

Am J Physiol Heart Circ Physiol 2007 Dec 5;293(6):H3396-403. Epub 2007 Oct 5.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

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http://www.physiology.org/doi/10.1152/ajpheart.00311.2007
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http://dx.doi.org/10.1152/ajpheart.00311.2007DOI Listing
December 2007

Structural analysis of obscurin gene in hypertrophic cardiomyopathy.

Biochem Biophys Res Commun 2007 Oct 13;362(2):281-7. Epub 2007 Aug 13.

Department of Molecular Pathogenesis, Medical Research Institute and Laboratory of Genome Diversity, School of Biomedical Science, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.07.183DOI Listing
October 2007

Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy.

Biochem Biophys Res Commun 2007 May 30;357(1):162-7. Epub 2007 Mar 30.

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.03.128DOI Listing
May 2007

Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy.

J Clin Invest 2007 May 19;117(5):1282-93. Epub 2007 Apr 19.

Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street. New York, NY 10032, USA.

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http://dx.doi.org/10.1172/JCI29042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849984PMC
May 2007

Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy.

J Muscle Res Cell Motil 2005 ;26(6-8):367-74

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-Ku, 101-0062, Tokyo , Japan.

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http://link.springer.com/content/pdf/10.1007/s10974-005-9018
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http://link.springer.com/10.1007/s10974-005-9018-5
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http://dx.doi.org/10.1007/s10974-005-9018-5DOI Listing
January 2007

Alpha B-crystallin mutation in dilated cardiomyopathy.

Biochem Biophys Res Commun 2006 Apr 8;342(2):379-86. Epub 2006 Feb 8.

Department of Molecular Pathogenesis, Medical Research Institute and Laboratory of Genome Diversity, School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.01.154DOI Listing
April 2006

Genetics of laminopathies.

Novartis Found Symp 2005 ;264:81-90; discussion 90-97, 227-30

Inserm U582, Institut de Myologie, Batiment Babinski, Groupe Hospitalier Pitié-Salpe'triire, 47, Boulevard de l'Hôpital, Paris, France.

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April 2005

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.

J Biol Chem 2004 Jun 30;279(26):27194-8. Epub 2004 Apr 30.

Department of Molecular Pathogenesis, Medical Research Institute and Laboratory of Genome Diversity, School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1074/jbc.M311953200DOI Listing
June 2004

Subchronic toxicity study of dietary N-acetylglucosamine in F344 rats.

Food Chem Toxicol 2004 Apr;42(4):687-95

Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

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http://dx.doi.org/10.1016/j.fct.2003.12.005DOI Listing
April 2004

A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C.

J Biol Chem 2004 Feb 3;279(8):6746-52. Epub 2003 Dec 3.

Department of Molecular Pathogenesis, Medical Research Institute, and Laboratory of Genome Diversity, School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M311849200
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http://dx.doi.org/10.1074/jbc.M311849200DOI Listing
February 2004

Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy.

Biochem Biophys Res Commun 2004 Jan;313(1):178-84

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2003.11.101DOI Listing
January 2004

Titin mutations as the molecular basis for dilated cardiomyopathy.

Biochem Biophys Res Commun 2002 Feb;291(2):385-93

Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1006/bbrc.2002.6448DOI Listing
February 2002