Publications by authors named "Takeshi Uchiumi"

100Publications

Genomic characteristics revealed by targeted exon sequencing of testicular germ cell tumors in Japanese men.

Int J Urol 2020 Oct 12. Epub 2020 Oct 12.

Departments of, Department of, Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/iju.14396DOI Listing
October 2020

Polymorphisms in androgen metabolism genes with serum testosterone levels and prognosis in androgen-deprivation therapy.

Urol Oncol 2020 Nov 22;38(11):849.e11-849.e18. Epub 2020 Jul 22.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.urolonc.2020.06.033DOI Listing
November 2020

High-throughput screen identifies 5-HT receptor as a modulator of AR and a therapeutic target for prostate cancer.

Prostate 2020 08 1;80(11):885-894. Epub 2020 Jun 1.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.24022DOI Listing
August 2020

Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes due to m.3243A > G mutation in a 76-year-old woman.

J Neurol Sci 2020 05 19;412:116791. Epub 2020 Mar 19.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2020.116791DOI Listing
May 2020

Genome-wide association study of genetic variations associated with treatment failure after intravesical bacillus Calmette-Guérin therapy for non-muscle invasive bladder cancer.

Cancer Immunol Immunother 2020 Jul 2;69(7):1155-1163. Epub 2020 Mar 2.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1007/s00262-020-02533-8DOI Listing
July 2020

Impaired plasmalogen synthesis dysregulates liver X receptor-dependent transcription in cerebellum.

J Biochem 2019 May 28. Epub 2019 May 28.

Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan.

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http://dx.doi.org/10.1093/jb/mvz043DOI Listing
May 2019

The impact of genetic polymorphism on CYP19A1 in androgen-deprivation therapy among Japanese men.

Cancer Chemother Pharmacol 2019 05 13;83(5):933-938. Epub 2019 Mar 13.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://link.springer.com/10.1007/s00280-019-03811-8
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http://dx.doi.org/10.1007/s00280-019-03811-8DOI Listing
May 2019

Toxic myopathy with multiple deletions in mitochondrial DNA associated with long-term use of oral anti-viral drugs for hepatitis B: A case study.

Neuropathology 2019 Apr 7;39(2):162-167. Epub 2019 Mar 7.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/neup.12548DOI Listing
April 2019

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation.

Cell Rep 2018 11;25(7):1800-1815.e4

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183164
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http://dx.doi.org/10.1016/j.celrep.2018.10.057DOI Listing
November 2018

Mineralocorticoid receptor signaling affects therapeutic effect of enzalutamide.

Prostate 2018 May 30. Epub 2018 May 30.

Department of Urology,, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.23661DOI Listing
May 2018

Isolated and repeated stroke-like episodes in a middle-aged man with a mitochondrial ND3 T10158C mutation: a case report.

BMC Neurol 2017 Dec 13;17(1):217. Epub 2017 Dec 13.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1186/s12883-017-1001-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729248PMC
December 2017

Doxycycline induces apoptosis via ER stress selectively to cells with a cancer stem cell-like properties: importance of stem cell plasticity.

Oncogenesis 2017 Nov 29;6(11):397. Epub 2017 Nov 29.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1038/s41389-017-0009-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868058PMC
November 2017

Neural-specific deletion of mitochondrial p32/C1qbp leads to leukoencephalopathy due to undifferentiated oligodendrocyte and axon degeneration.

Sci Rep 2017 11 9;7(1):15131. Epub 2017 Nov 9.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1038/s41598-017-15414-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680297PMC
November 2017

Amelogenin induces M2 macrophage polarisation via PGE2/cAMP signalling pathway.

Arch Oral Biol 2017 Nov 12;83:241-251. Epub 2017 Aug 12.

Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.archoralbio.2017.08.005DOI Listing
November 2017

Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation.

Sci Rep 2017 08 16;7(1):8315. Epub 2017 Aug 16.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1038/s41598-017-08088-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559520PMC
August 2017

A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.

Rinsho Shinkeigaku 2017 07 22;57(7):400-401. Epub 2017 Jul 22.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University.

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http://dx.doi.org/10.5692/clinicalneurol.cn-001044DOI Listing
July 2017

p32 is Required for Appropriate Interleukin-6 Production Upon LPS Stimulation and Protects Mice from Endotoxin Shock.

EBioMedicine 2017 Jun 11;20:161-172. Epub 2017 May 11.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478242PMC
June 2017

Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses.

Cardiovasc Res 2017 Aug;113(10):1173-1185

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-Ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1093/cvr/cvx095DOI Listing
August 2017

Protein kinase C regulates Twist1 expression via NF-κB in prostate cancer.

Endocr Relat Cancer 2017 04 21;24(4):171-180. Epub 2017 Feb 21.

Department of UrologyGraduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1530/ERC-16-0384DOI Listing
April 2017

The clinical presentation and genotype of protein C deficiency with double mutations of the protein C gene.

Pediatr Blood Cancer 2017 Jul 23;64(7). Epub 2017 Jan 23.

Department of Pediatrics, Yamaguchi University Graduate School of Medicine, Ube, Japan.

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http://dx.doi.org/10.1002/pbc.26404DOI Listing
July 2017

Mitochondrial nucleic acid binding proteins associated with diseases.

Front Biosci (Landmark Ed) 2017 01 1;22:168-179. Epub 2017 Jan 1.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.2741/4479DOI Listing
January 2017

Serum depletion induced cancer stem cell-like phenotype due to nitric oxide synthesis in oncogenic HRas transformed cells.

Oncotarget 2016 Nov;7(46):75221-75234

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.18632/oncotarget.12117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342736PMC
November 2016

Comparison of the Abbott RealTime HCV and Roche COBAS Ampliprep/COBAS TaqMan HCV assays for the monitoring of sofosbuvir-based therapy.

Antivir Ther 2017 15;22(1):61-70. Epub 2016 Sep 15.

Kyushu General Internal Medicine Center, Haradoi Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.3851/IMP3085DOI Listing
January 2018

Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts.

Eur J Oral Sci 2016 06 17;124(3):241-5. Epub 2016 Apr 17.

Department of Pediatric Dentistry, Graduate School of Dental Science, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/eos.12270DOI Listing
June 2016

[A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes].

Rinsho Shinkeigaku 2016 8;56(3):204-7. Epub 2016 Mar 8.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University.

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http://dx.doi.org/10.5692/clinicalneurol.cn-000834DOI Listing
September 2017

Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7.

J Natl Cancer Inst 2016 Jul 8;108(7). Epub 2016 Feb 8.

Affiliations of authors:Department of Urology (MS, KI, AY, MI, AT, JI, KT, SN), Department of Anatomic Pathology (KI, YO), and Department of Clinical Chemistry and Laboratory Medicine (TU), Graduate School of Medical Sciences, Kyushu University , Fukuoka , Japan ; Department of Urology, School of Medicine, University of Occupational and Environmental Health , Kitakyushu , Japan (NF); Department of Urology, School of Medicine, Jikei University , Tokyo , Japan (HK).

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http://dx.doi.org/10.1093/jnci/djw005DOI Listing
July 2016

Crosstalk between epithelial-mesenchymal transition and castration resistance mediated by Twist1/AR signaling in prostate cancer.

Endocr Relat Cancer 2015 Dec 26;22(6):889-900. Epub 2015 Aug 26.

Departments of UrologyAnatomic PathologyGraduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanDepartment of UrologySchool of Medicine, Jikei University, Tokyo 105-0003, JapanDepartment of Clinical Chemistry and Laboratory MedicineGraduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1530/ERC-15-0225DOI Listing
December 2015

SRD5A gene polymorphism in Japanese men predicts prognosis of metastatic prostate cancer with androgen-deprivation therapy.

Eur J Cancer 2015 Sep 11;51(14):1962-9. Epub 2015 Jul 11.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.ejca.2015.06.122DOI Listing
September 2015

Grp78 Is Critical for Amelogenin-Induced Cell Migration in a Multipotent Clonal Human Periodontal Ligament Cell Line.

J Cell Physiol 2016 Feb;231(2):414-27

Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/jcp.25087DOI Listing
February 2016

A CADASIL-Like Case with a Novel Noncysteine Mutation of the NOTCH3 Gene and Granular Deposits in the Renal Arterioles.

Case Rep Neurol Med 2015 9;2015:431461. Epub 2015 Mar 9.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1155/2015/431461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365362PMC
April 2015

Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast.

J Cell Sci 2014 Jul 16;127(Pt 14):3184-96. Epub 2014 May 16.

Laboratory of Biosignaling, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan

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http://dx.doi.org/10.1242/jcs.153254DOI Listing
July 2014

PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells.

J Mol Endocrinol 2014 Aug 29;53(1):31-41. Epub 2014 Apr 29.

Departments of UrologyClinical Chemistry and Laboratory MedicineGraduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1530/JME-13-0303DOI Listing
August 2014

Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer.

Prostate 2014 Jun 17;74(9):959-69. Epub 2014 Apr 17.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.22813DOI Listing
June 2014

Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer.

Prostate 2014 Jun 12;74(8):829-38. Epub 2014 Apr 12.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.22799DOI Listing
June 2014

Identification of novel amelogenin-binding proteins by proteomics analysis.

PLoS One 2013 22;8(10):e78129. Epub 2013 Oct 22.

Department of Periodontology, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078129PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805512PMC
May 2014

[The functional and pathological analysis of mitochondrial protein p32].

Rinsho Byori 2013 Jun;61(6):493-500

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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June 2013

Casein kinase 2 is essential for mitophagy.

EMBO Rep 2013 Sep 30;14(9):788-94. Epub 2013 Jul 30.

Laboratory of Biosignaling, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510.

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http://dx.doi.org/10.1038/embor.2013.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790056PMC
September 2013

Interaction between docetaxel resistance and castration resistance in prostate cancer: implications of Twist1, YB-1, and androgen receptor.

Prostate 2013 Sep 14;73(12):1336-44. Epub 2013 Jun 14.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.22681DOI Listing
September 2013

Human heterochromatin protein 1 isoforms regulate androgen receptor signaling in prostate cancer.

J Mol Endocrinol 2013 Jun 23;50(3):401-9. Epub 2013 Apr 23.

Departments of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1530/JME-13-0024DOI Listing
June 2013

Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells.

Endocr Relat Cancer 2013 Jun 30;20(3):431-41. Epub 2013 May 30.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1530/ERC-12-0344DOI Listing
June 2013

Twist1 and Y-box-binding protein-1 are potential prognostic factors in bladder cancer.

Urol Oncol 2014 Jan 6;32(1):31.e1-7. Epub 2013 Feb 6.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.urolonc.2012.11.003DOI Listing
January 2014

Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Biosci Rep 2013 Feb 5;33(2):e00021. Epub 2013 Feb 5.

*Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1042/BSR20120097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564035PMC
February 2013

Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin-Johnson syndrome.

Hepatol Res 2013 May 10;43(5):569-75. Epub 2012 Oct 10.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka.

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http://doi.wiley.com/10.1111/j.1872-034X.2012.01103.x
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http://dx.doi.org/10.1111/j.1872-034X.2012.01103.xDOI Listing
May 2013

Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients.

Biosci Rep 2012 Dec;32(6):631-9

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Maidashi, Higashi-ku, Fukuoka, Japan.

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http://dx.doi.org/10.1042/BSR20120046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497730PMC
December 2012

p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability.

Nucleic Acids Res 2012 Oct 16;40(19):9717-37. Epub 2012 Aug 16.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1093/nar/gks774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479211PMC
October 2012

Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer.

Prostate 2012 May 30;72(7):741-51. Epub 2011 Aug 30.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.21478DOI Listing
May 2012

Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins.

Mitochondrion 2012 May 3;12(3):391-8. Epub 2012 Mar 3.

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.mito.2012.02.004DOI Listing
May 2012

Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA.

Biochem J 2012 Apr;443(2):573-84

Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka, Japan.

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http://dx.doi.org/10.1042/BJ20111728DOI Listing
April 2012

The role of TFAM-associated proteins in mitochondrial RNA metabolism.

Biochim Biophys Acta 2012 May 31;1820(5):565-70. Epub 2011 Aug 31.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.bbagen.2011.08.014DOI Listing
May 2012

Phosphorylation of Serine 114 on Atg32 mediates mitophagy.

Mol Biol Cell 2011 Sep 14;22(17):3206-17. Epub 2011 Jul 14.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1091/mbc.E11-02-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164466PMC
September 2011

Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression.

Endocr Relat Cancer 2011 Aug 11;18(4):505-17. Epub 2011 Jul 11.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1530/ERC-11-0017DOI Listing
August 2011

Peroxiredoxin 2 in the nucleus and cytoplasm distinctly regulates androgen receptor activity in prostate cancer cells.

Free Radic Biol Med 2011 Jul 14;51(1):78-87. Epub 2011 Apr 14.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.04.001DOI Listing
July 2011

Twist1 and Y-box-binding protein-1 promote malignant potential in bladder cancer cells.

BJU Int 2011 Jul 17;108(2 Pt 2):E142-9. Epub 2010 Nov 17.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1464-410X.2010.09810.xDOI Listing
July 2011

Role of ZNF143 in tumor growth through transcriptional regulation of DNA replication and cell-cycle-associated genes.

Cancer Sci 2010 Dec 23;101(12):2538-45. Epub 2010 Sep 23.

Department of Molecular Biology Otorhinolaryngology Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01725.xDOI Listing
December 2010

Sensitivity of doxorubicin-resistant cells to sorafenib: possible role for inhibition of eukaryotic initiation factor-2alpha phosphorylation.

Int J Oncol 2010 Aug;37(2):509-17

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8252, Japan.

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http://dx.doi.org/10.3892/ijo_00000700DOI Listing
August 2010

ERAL1 is associated with mitochondrial ribosome and elimination of ERAL1 leads to mitochondrial dysfunction and growth retardation.

Nucleic Acids Res 2010 Sep 29;38(16):5554-68. Epub 2010 Apr 29.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, 3-1-1, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1093/nar/gkq305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938226PMC
September 2010

Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition.

Int J Oncol 2010 Jun;36(6):1521-31

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8252, Japan.

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http://dx.doi.org/10.3892/ijo_00000639DOI Listing
June 2010

Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin.

Cancer Sci 2010 May 20;101(5):1177-85. Epub 2010 Jan 20.

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01503.xDOI Listing
May 2010

Tip60 promotes prostate cancer cell proliferation by translocation of androgen receptor into the nucleus.

Prostate 2010 Apr;70(5):540-54

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/pros.21088DOI Listing
April 2010

[Cisplatin sensitivity transcriptional factor and mitochondrial DNA maintenance protein].

Rinsho Byori 2009 Oct;57(10):978-86

Department of Clinical Chemistry and Laboratory Medicine, Graduated School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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October 2009

DNA conformation-dependent activities of human mitochondrial RNA polymerase.

Genes Cells 2009 Aug 14;14(8):1029-42. Epub 2009 Jul 14.

Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2009.01328.xDOI Listing
August 2009

A new mechanism for primary resistance to gefitinib in lung adenocarcinoma: the role of a novel G796A mutation in exon 20 of EGFR.

Anticancer Res 2007 Jul-Aug;27(4B):2297-303

Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan.

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September 2007

p73gamma transactivates the p21 promoter through preferential interaction with the p300/CBP-associated factor in human prostate cancer cells.

Oncol Rep 2007 Aug;18(2):411-6

Department of Molecular Biology, School of Medicine, University of Occupational and Environmental Health Japan, Fukuoka 807-8555, Japan.

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August 2007

DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation.

Cancer Sci 2007 Jun 18;98(6):858-63. Epub 2007 Apr 18.

Department of Molecular Biology, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Fukuoka, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2007.00476.xDOI Listing
June 2007

Inhibitory effects of angiotensin II receptor antagonists and leukotriene receptor antagonists on the transport of human organic anion transporter 4.

J Pharm Pharmacol 2006 Nov;58(11):1499-505

Department of Medico-Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Fukuoka, Japan.

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http://dx.doi.org/10.1211/jpp.58.11.0011DOI Listing
November 2006

YB-1 is important for an early stage embryonic development: neural tube formation and cell proliferation.

J Biol Chem 2006 Dec 2;281(52):40440-9. Epub 2006 Nov 2.

Department of Molecular Biology, University of Occupational and Environmental Health, School of Medicine, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

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http://dx.doi.org/10.1074/jbc.M605948200DOI Listing
December 2006

Expression and cellular localization of dbpC/Contrin in germ cell tumor cell lines.

Biochim Biophys Acta 2006 Jan-Feb;1759(1-2):80-8. Epub 2006 Mar 27.

Department of Molecular Biology, University of Occupational and Environmental Health School of Medicine, Iseigaoka, Kitakyushu 807-8555, Japan.

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http://dx.doi.org/10.1016/j.bbaexp.2006.02.005DOI Listing
July 2006

Transcription factors and drug resistance.

Eur J Cancer 2005 Nov 4;41(16):2577-86. Epub 2005 Oct 4.

Department of Molecular Biology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Fukuoka 807-8555, Japan.

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http://dx.doi.org/10.1016/j.ejca.2005.08.007DOI Listing
November 2005

Functional analysis of organic cation transporter 3 expressed in human placenta.

J Pharmacol Exp Ther 2005 Nov 4;315(2):888-95. Epub 2005 Aug 4.

Department of Medico-Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1124/jpet.105.086827DOI Listing
November 2005

Differential regulation of the human MRP2 and MRP3 gene expression by glucocorticoids.

J Steroid Biochem Mol Biol 2005 Aug;96(3-4):229-34

Laboratory of Transcriptional Regulation, Centre of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.

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http://linkinghub.elsevier.com/retrieve/pii/S096007600500206
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http://dx.doi.org/10.1016/j.jsbmb.2005.03.004DOI Listing
August 2005

p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

J Cell Sci 2005 May 12;118(Pt 9):1821-32. Epub 2005 Apr 12.

Department of Molecular Biology, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1242/jcs.02307DOI Listing
May 2005

ATP-binding cassette superfamily transporter gene expression in human soft tissue sarcomas.

Int J Cancer 2005 May;114(6):854-62

Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1002/ijc.20589DOI Listing
May 2005

The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.

Mol Cancer Ther 2004 Nov;3(11):1485-92

Research Center for Innovative Cancer Therapy of the 21st Century COE Program for Medical Science, Kurume University, Fukuoka, Japan.

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November 2004

Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.

Br J Pharmacol 2004 Dec 25;143(7):856-64. Epub 2004 Oct 25.

Department of Medico-Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

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http://doi.wiley.com/10.1038/sj.bjp.0706008
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http://dx.doi.org/10.1038/sj.bjp.0706008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575941PMC
December 2004

Interleukin-1beta represses MRP2 gene expression through inactivation of interferon regulatory factor 3 in HepG2 cells.

Hepatology 2004 Jun;39(6):1574-82

Department of Medical Biochemistry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

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http://dx.doi.org/10.1002/hep.20216DOI Listing
June 2004