Publications by authors named "Takeshi Shimamura"

86Publications

Effect of FOLFIRINOX as second-line chemotherapy for metastatic pancreatic cancer after gemcitabine-based chemotherapy failure.

Medicine (Baltimore) 2017 May;96(19):e6769

aGraduate School of Medicine, Department of Oncology, Yokohama City University, Japan bShimamura Clinic and Yokohama City University Graduate School of Medicine Department of Oncology cGraduate School of Medicine, Department of Gastroenterological Surgery, Yokohama City University, Japan.

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http://dx.doi.org/10.1097/MD.0000000000006769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428587PMC
May 2017

Sorafenib Monotherapy in a Patient with Unresectable Hepatic Epithelioid Hemangioendothelioma.

Case Rep Oncol 2016 Jan-Apr;9(1):134-7. Epub 2016 Feb 19.

Department of Oncology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

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http://dx.doi.org/10.1159/000443986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899657PMC
June 2016

Heterogeneity in Tumors and Resistance to EGFR TKI Therapy-Response.

Cancer Res 2016 05 2;76(10):3111. Epub 2016 May 2.

Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0610DOI Listing
May 2016

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors.

Cancer Discov 2013 Dec 27;3(12):1355-63. Epub 2013 Sep 27.

Departments of 1Medicine and 2Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute; 3Harvard Medical School; 4Ludwig Institute for Cancer Research; 5Department of Neurosurgery, Massachusetts General Hospital; 6Belfer Institute for Applied Cancer Science; 7Department of Pathology, Brigham and Women's Hospital, Boston; 8Broad Institute, Cambridge, Massachusetts; 9UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and 10Department of Molecular Pharmacology and Therapeutics, Oncology Institute, Loyola University, Chicago, Illinois; 11Department of Physiology, University of Valencia, Valencia, Spain.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864135PMC
December 2013

Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer.

Clin Cancer Res 2013 Nov 17;19(22):6183-92. Epub 2013 Sep 17.

Authors' Affiliations: Department of Molecular Pharmacology and Therapeutics, Oncology Research Institute, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois; Departments of Medical Oncology and Radiation Oncology; Belfer Institute for Applied Cancer Science; Ludwig Center at Dana-Farber/Harvard Cancer Center; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute; Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, Massachusetts; Departament de Fisiologia, Facultat de Farmàcia, Universitat de València, Valencia, Spain; and Department of Pediatrics, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-3904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838895PMC
November 2013

HIF1α and HIF2α independently activate SRC to promote melanoma metastases.

J Clin Invest 2013 May 8;123(5):2078-93. Epub 2013 Apr 8.

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.

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http://dx.doi.org/10.1172/JCI66715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635738PMC
May 2013

A novel scoring system for arterial invasion of pancreatic body and tail cancer based on multidetector row computed tomography and biomarkers.

Pancreatology 2013 Mar-Apr;13(2):161-9. Epub 2013 Jan 22.

Division of Gastroenterology, Yokohama City University School of Medicine, 3-9 Fukuura, Yokohama 236-0004, Japan.

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http://dx.doi.org/10.1016/j.pan.2012.12.364DOI Listing
October 2013

Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway.

Cancer Res 2013 Jan 19;73(2):834-43. Epub 2012 Nov 19.

Lowe Center for Thoracic Oncology, Department of Medical Oncology, Dana Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-2066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994895PMC
January 2013

Suppression of neointimal hyperplasia following angioplasty-induced vascular injury in pigs infected with swinepox virus.

Open Virol J 2012 15;6:91-6. Epub 2012 Oct 15.

Laboratory of Virology, Department of Biological Sciences, Western Michigan University, 1903 West Michigan Ave, 3441 Wood Hall, Kalamazoo, MI 49008-5410, USA.

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http://dx.doi.org/10.2174/1874357901206010091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486964PMC
November 2012

Endoscopic ultrasonographic findings predict the risk of carcinoma in branch duct intraductal papillary mucinous neoplasms of the pancreas.

Pancreatology 2012 Mar-Apr;12(2):141-5. Epub 2012 Jan 14.

Gastroenterology Division, Yokohama City University Graduate School of Medicine, 3-9, Fuku-ura, Kanazawa-ku, Yokohama 236-0004, Japan.

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http://dx.doi.org/10.1016/j.pan.2011.12.008DOI Listing
November 2012

Rectal carcinoma with metachronous metastasis to the extrahepatic bile duct without liver tumor.

Clin J Gastroenterol 2011 Aug 13;4(4):278-282. Epub 2011 Jul 13.

Gastroenterological Surgery Division, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

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http://dx.doi.org/10.1007/s12328-011-0240-yDOI Listing
August 2011

Complications of the treatment of endoscopic biliary strictures developing after liver transplantation.

J Hepatobiliary Pancreat Sci 2011 Mar;18(2):202-10

Gastroenterology Division, Yokohama City University School of Medicine, 3-9 Fuku-ura, Kanazawa-ku, Yokohama, Japan.

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http://dx.doi.org/10.1007/s00534-010-0330-0DOI Listing
March 2011

Interleukin 13 mediates signal transduction through interleukin 13 receptor alpha2 in pancreatic ductal adenocarcinoma: role of IL-13 Pseudomonas exotoxin in pancreatic cancer therapy.

Clin Cancer Res 2010 Jan 12;16(2):577-86. Epub 2010 Jan 12.

Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-2015DOI Listing
January 2010

IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma.

Int J Cancer 2009 Mar;124(6):1440-8

Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/ijc.24067DOI Listing
March 2009

Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model.

J Immunol 2008 Oct;181(7):4656-65

Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.181.7.4656DOI Listing
October 2008

Heat shock protein 90 inhibition in lung cancer.

J Thorac Oncol 2008 Jun;3(6 Suppl 2):S152-9

Department of Medicine, Brigham and Women's Hospital and Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/JTO.0b013e318174ea3aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475350PMC
June 2008

Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.

Eur J Med Chem 2008 Jun 14;43(6):1206-15. Epub 2007 Sep 14.

Faculty of Pharmaceutical Sciences, Josai University, Keyakidai 1-1, Sakado, Saitama 350-0295, Japan.

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http://dx.doi.org/10.1016/j.ejmech.2007.08.009DOI Listing
June 2008

Interleukin-4 cytotoxin therapy synergizes with gemcitabine in a mouse model of pancreatic ductal adenocarcinoma.

Cancer Res 2007 Oct;67(20):9903-12

Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, NIH, Bethesda, MD 20892, USA.

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http://cancerres.aacrjournals.org/content/canres/67/20/9903.
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-4558DOI Listing
October 2007

NF-kappaB controls growth of glioblastomas/astrocytomas.

Mol Cell Biochem 2008 Jan 9;307(1-2):141-7. Epub 2007 Sep 9.

Department of Biological Sciences, Western Michigan University, Kalamazoo, MI 49008, USA.

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http://link.springer.com/10.1007/s11010-007-9593-4
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http://dx.doi.org/10.1007/s11010-007-9593-4DOI Listing
January 2008

Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors.

Cancer Biol Ther 2007 May 13;6(5):661-7. Epub 2007 Feb 13.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.4161/cbt.6.5.4003DOI Listing
May 2007

Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy.

Cancer 2006 Sep;107(6):1407-18

Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA.

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http://doi.wiley.com/10.1002/cncr.22134
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http://dx.doi.org/10.1002/cncr.22134DOI Listing
September 2006

Pleural effusions following endoscopic injection sclerotherapy for cirrhotic patients with esophageal varices.

Hepatogastroenterology 2006 May-Jun;53(69):376-80

Third Department of Internal Medicine, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan.

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October 2007

The IL-4 and IL-13 pseudomonas exotoxins: new hope for brain tumor therapy.

Neurosurg Focus 2006 Apr 15;20(4):E11. Epub 2006 Apr 15.

Tumor Vaccines and Biotechnology Branch, Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, Maryland 20892, USA.

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https://thejns.org/view/journals/neurosurg-focus/20/4/foc.20
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http://dx.doi.org/10.3171/foc.2006.20.4.6DOI Listing
April 2006

Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins.

Cancer Res 2005 Jul;65(14):6401-8

Lowe Center for Thoracic Oncology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0933DOI Listing
July 2005

Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas.

Clin Cancer Res 2002 Aug;8(8):2570-5

Pathology Division, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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August 2002

Activation of NF-kappaB is required for PDGF-B chain to transform NIH3T3 cells.

Exp Cell Res 2002 Mar;274(1):157-67

Department of Biological Sciences, Western Michigan University, Kalamazoo, Michigan 49008, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270195449
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http://dx.doi.org/10.1006/excr.2001.5449DOI Listing
March 2002