Publications by authors named "Takeshi Otowa"

64Publications

Shared genetic etiology between anxiety disorders and psychiatric and related intermediate phenotypes.

Psychol Med 2020 03 28;50(4):692-704. Epub 2019 Mar 28.

Center for Physical and Mental Health, Mie University, Mie, Japan.

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http://dx.doi.org/10.1017/S003329171900059XDOI Listing
March 2020

An epigenome-wide methylation study of healthy individuals with or without depressive symptoms.

J Hum Genet 2018 Mar 5;63(3):319-326. Epub 2018 Jan 5.

Department of Physical and Health Education, Graduate School of Education, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/s10038-017-0382-yDOI Listing
March 2018

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

Epigenome-wide association study of DNA methylation in panic disorder.

Clin Epigenetics 2017 21;9. Epub 2017 Jan 21.

Department of Physical and Health Education, Graduate School of Education, The University of Tokyo, 7-3-1 Hongo, Bunkyo Ward, Tokyo, 113-0033 Japan.

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http://dx.doi.org/10.1186/s13148-016-0307-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270210PMC
July 2017

Oxytocin receptor gene variations predict neural and behavioral response to oxytocin in autism.

Soc Cogn Affect Neurosci 2017 03;12(3):496-506

Department of Neuropsychiatry Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1093/scan/nsw150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390696PMC
March 2017

Assessment and characterization of phenotypic heterogeneity of anxiety disorders across five large cohorts.

Int J Methods Psychiatr Res 2016 12 15;25(4):255-266. Epub 2016 Jul 15.

Department of Psychiatry, Virginia Institute for Psychiatry and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1002/mpr.1519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145750PMC
December 2016

The Association of BDNF Val66Met Polymorphism With Trait Anxiety in Panic Disorder.

J Neuropsychiatry Clin Neurosci 2014 ;26(4):344-51

From the Dept. of Psychiatry, Division of Neuroscience, Graduate School of Medicine, Brain Science and Animal Model Research Center, Mie University, Mie, Japan (YK, HT, MO); the Dept. of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan (TO); the Laboratory of Health Education, Graduate School of Education, University of Tokyo, Tokyo, Japan (TS); the Research Center for Panic Disorder, Nagoya Mental Clinic, Nagoya, Japan (HK); and the Dept. of Psychiatry, Tokyo Metropolitan Matsuzawa Hospital, Tokyo, Japan (YO).

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http://dx.doi.org/10.1176/appi.neuropsych.11120359DOI Listing
December 2015

Genetics of anxiety disorders: Genetic epidemiological and molecular studies in humans.

Psychiatry Clin Neurosci 2015 Jul 5;69(7):388-401. Epub 2015 Apr 5.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, USA.

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http://doi.wiley.com/10.1111/pcn.12291
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http://dx.doi.org/10.1111/pcn.12291DOI Listing
July 2015

Anger tendency may be associated with duration of illness in panic disorder.

Biopsychosoc Med 2015 1;9. Epub 2015 Mar 1.

Office for Mental Health Support, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 Japan ; Graduate School of Education, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 Japan.

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http://dx.doi.org/10.1186/s13030-015-0035-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349781PMC
March 2015

Genome-wide and gene-based association studies of anxiety disorders in European and African American samples.

PLoS One 2014 12;9(11):e112559. Epub 2014 Nov 12.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112559PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229211PMC
April 2016

The impact of childhood parental loss on risk for mood, anxiety and substance use disorders in a population-based sample of male twins.

Psychiatry Res 2014 Dec 1;220(1-2):404-9. Epub 2014 Aug 1.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1016/j.psychres.2014.07.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385714PMC
December 2014

Gender-specific association between the COMT Val158Met polymorphism and openness to experience in panic disorder patients.

Neuropsychobiology 2014 16;69(3):165-74. Epub 2014 May 16.

Department of Psychiatry, Division of Neuroscience, Graduate School of Medicine, Brain Science and Animal Model Research Center, Mie University, Tsu, Japan.

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http://dx.doi.org/10.1159/000360737DOI Listing
February 2015

Gene×gene×gender interaction of BDNF and COMT genotypes associated with panic disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Jun 4;51:119-25. Epub 2014 Feb 4.

Department of Psychiatry, Division of Neuroscience, Graduate School of Medicine, Brain Science and Animal Model Research Center (BSAM), Mie University, Mie, Japan.

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http://dx.doi.org/10.1016/j.pnpbp.2014.01.020DOI Listing
June 2014

Parenting and risk for mood, anxiety and substance use disorders: a study in population-based male twins.

Soc Psychiatry Psychiatr Epidemiol 2013 Nov 24;48(11):1841-9. Epub 2013 Jan 24.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA,

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http://dx.doi.org/10.1007/s00127-013-0656-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661760PMC
November 2013

Prioritization and association analysis of murine-derived candidate genes in anxiety-spectrum disorders.

Biol Psychiatry 2011 Nov 25;70(9):888-96. Epub 2011 Aug 25.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000632231100725
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http://dx.doi.org/10.1016/j.biopsych.2011.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191234PMC
November 2011

An association analysis of Per2 with panic disorder in the Japanese population.

J Hum Genet 2011 Oct 4;56(10):748-50. Epub 2011 Aug 4.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2011.94DOI Listing
October 2011

Association of RGS2 variants with panic disorder in a Japanese population.

Am J Med Genet B Neuropsychiatr Genet 2011 Jun 22;156B(4):430-4. Epub 2011 Mar 22.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

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http://dx.doi.org/10.1002/ajmg.b.31178DOI Listing
June 2011

Association study of PDE4B with panic disorder in the Japanese population.

Prog Neuropsychopharmacol Biol Psychiatry 2011 Mar 22;35(2):545-9. Epub 2010 Dec 22.

Department of Neuropsychiatry, Graduate School of Medicine, the University of Tokyo, Tokyo 113-8655, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S02785846100050
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http://dx.doi.org/10.1016/j.pnpbp.2010.12.013DOI Listing
March 2011

An association study between the dymeclin gene and schizophrenia in the Japanese population.

J Hum Genet 2010 Sep 17;55(9):631-4. Epub 2010 Jun 17.

Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1038/jhg.2010.72DOI Listing
September 2010

The association between oxytocin receptor gene (OXTR) polymorphisms and affective temperaments, as measured by TEMPS-A.

J Affect Disord 2010 Dec 21;127(1-3):31-7. Epub 2010 May 21.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jad.2010.04.014DOI Listing
December 2010

Six-year stability of affective temperaments as measured by TEMPS-A.

Psychopathology 2010 28;43(4):240-7. Epub 2010 Apr 28.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1159/000313522DOI Listing
September 2010

Replication study of association between ADCYAP1 gene polymorphisms and schizophrenia.

Psychiatr Genet 2010 Jun;20(3):123-5

Department of Medical Genetics, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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https://insights.ovid.com/crossref?an=00041444-900000000-999
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http://dx.doi.org/10.1097/YPG.0b013e32833a1f52DOI Listing
June 2010

A two-stage case-control association study of PADI2 with schizophrenia.

J Hum Genet 2009 Jul 29;54(7):430-2. Epub 2009 May 29.

Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan.

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http://www.nature.com/articles/jhg200952
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http://dx.doi.org/10.1038/jhg.2009.52DOI Listing
July 2009

Genome-wide association study of panic disorder in the Japanese population.

J Hum Genet 2009 Feb 23;54(2):122-6. Epub 2009 Jan 23.

Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2008.17DOI Listing
February 2009

Two-stage case-control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia.

J Hum Genet 2009 Jan 9;54(1):62-5. Epub 2009 Jan 9.

Department of Psychiatry, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan.

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http://dx.doi.org/10.1038/jhg.2008.4DOI Listing
January 2009

Appropriate data cleaning methods for genome-wide association study.

J Hum Genet 2008 12;53(10):886-893. Epub 2008 Aug 12.

Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1007/s10038-008-0322-yDOI Listing
November 2008

Association study of monoamine oxidase and catechol-O-methyltransferase genes with smoking behavior.

Pharmacogenet Genomics 2007 Oct;17(10):867-72

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/FPC.0b013e3282e9a51eDOI Listing
October 2007

Association study between the TNXB locus and schizophrenia in a Japanese population.

Am J Med Genet B Neuropsychiatr Genet 2007 Apr;144B(3):305-9

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan.

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http://dx.doi.org/10.1002/ajmg.b.30441DOI Listing
April 2007

No association of DRD2, DRD3, and tyrosine hydroxylase gene polymorphisms with personality traits in the Japanese population.

Behav Brain Funct 2006 Oct 3;2:32. Epub 2006 Oct 3.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1186/1744-9081-2-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1601960PMC
October 2006

Insertional polymorphism of endogenous retrovirus HERV-K115 in schizophrenia.

Neurosci Lett 2006 Nov 26;408(3):226-9. Epub 2006 Sep 26.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1016/j.neulet.2006.09.004DOI Listing
November 2006

No association between the CNTF null mutation and schizophrenia or personality.

Psychiatr Genet 2006 Oct;16(5):217-9

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/01.ypg.0000242189.05656.9dDOI Listing
October 2006

No association between the metabotropic glutamate receptor type 3 gene (GRM3) and schizophrenia in a Japanese population.

Schizophr Res 2006 Dec 9;88(1-3):260-4. Epub 2006 Aug 9.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-8655 Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S092099640600319
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http://dx.doi.org/10.1016/j.schres.2006.07.008DOI Listing
December 2006

Association study of the dysbindin (DTNBP1) gene in schizophrenia from the Japanese population.

Neurosci Res 2006 Oct 31;56(2):154-8. Epub 2006 Jul 31.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.neures.2006.06.009DOI Listing
October 2006

No evidence for an association between the BDNF Val66Met polymorphism and schizophrenia or personality traits.

Schizophr Res 2006 Oct 18;87(1-3):45-7. Epub 2006 Jul 18.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo113-8655, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S092099640600295
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http://dx.doi.org/10.1016/j.schres.2006.06.029DOI Listing
October 2006

No association between the Clara cell secretory protein (CC16) gene polymorphism and personality traits.

Prog Neuropsychopharmacol Biol Psychiatry 2006 Aug 9;30(6):1122-4. Epub 2006 Jun 9.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan.

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http://dx.doi.org/10.1016/j.pnpbp.2006.04.019DOI Listing
August 2006

No association of 5-HT2C, 5-HT6, and tryptophan hydroxylase-1 gene polymorphisms with personality traits in the Japanese population.

Neurosci Lett 2006 Jul 8;403(1-2):100-2. Epub 2006 May 8.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.neulet.2006.04.020DOI Listing
July 2006

Association between dopamine D4 receptor (DRD4) exon III polymorphism and Neuroticism in the Japanese population.

Neurosci Lett 2006 May 10;398(3):333-6. Epub 2006 Feb 10.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.neulet.2006.01.020DOI Listing
May 2006

Combined analysis of association between personality traits and three functional polymorphisms in the tyrosine hydroxylase, monoamine oxidase A, and catechol-O-methyltransferase genes.

Neurosci Res 2006 Mar 19;54(3):180-5. Epub 2005 Dec 19.

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1016/j.neures.2005.11.003DOI Listing
March 2006

Season of birth effect on personality in a general population.

Neurosci Lett 2004 Jul;365(2):120-3

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, Japan.

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http://dx.doi.org/10.1016/j.neulet.2004.04.064DOI Listing
July 2004

Mitochondrial DNA polymorphisms and extraversion.

Am J Med Genet B Neuropsychiatr Genet 2004 Jul;128B(1):76-9

Department of Psychiatry, Health Service Center, University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo 113, Japan.

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http://dx.doi.org/10.1002/ajmg.b.20141DOI Listing
July 2004

Association of six polymorphisms of the NOTCH4 gene with schizophrenia in the Japanese population.

Am J Med Genet B Neuropsychiatr Genet 2004 Jul;128B(1):37-40

Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1Hongo, Bunkyo-ku, Tokyo 113, Japan.

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http://dx.doi.org/10.1002/ajmg.b.30010DOI Listing
July 2004