Takeshi Kezuka

Takeshi Kezuka

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Takeshi Kezuka

Publications by authors named "Takeshi Kezuka"

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Epidemiologic and Clinical Characteristics of Optic Neuritis in Japan.

Ophthalmology 2019 Oct 6;126(10):1385-1398. Epub 2019 May 6.

Department of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2019.04.042DOI Listing
October 2019

Clinical features of anterior uveitis caused by three different herpes viruses.

Int Ophthalmol 2019 May 27. Epub 2019 May 27.

Department of Ophthalmology, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

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http://link.springer.com/10.1007/s10792-019-01125-5
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http://dx.doi.org/10.1007/s10792-019-01125-5DOI Listing
May 2019

Role of PU.1 Expression as an Inflammatory Marker in Experimental Autoimmune Uveoretinitis.

Ocul Immunol Inflamm 2018 27;26(6):951-963. Epub 2017 Apr 27.

a Department of Ophthalmology , Tokyo Medical University , Shinjuku-ku , Tokyo , Japan.

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http://dx.doi.org/10.1080/09273948.2017.1299867DOI Listing
September 2018

Evaluation of efficacy of infliximab for retinal vasculitis and extraocular symptoms in Behçet disease.

Jpn J Ophthalmol 2018 May 26;62(3):390-397. Epub 2018 Mar 26.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

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http://link.springer.com/10.1007/s10384-018-0589-2
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http://dx.doi.org/10.1007/s10384-018-0589-2DOI Listing
May 2018

Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis.

Jpn J Ophthalmol 2018 Mar 14;62(2):101-108. Epub 2018 Feb 14.

Department of Orthoptics and Visual Science, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.

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http://dx.doi.org/10.1007/s10384-018-0561-1DOI Listing
March 2018

Aqueous immune mediators in malignant uveal melanomas in comparison to benign pigmented intraocular tumors.

Graefes Arch Clin Exp Ophthalmol 2017 Feb 22;255(2):393-399. Epub 2016 Nov 22.

Department of Ophthalmology, Tokyo Medical University Hospital, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

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http://dx.doi.org/10.1007/s00417-016-3541-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5285432PMC
February 2017

Clinical Profile of Anti-Myelin Oligodendrocyte Glycoprotein Antibody Seropositive Cases of Optic Neuritis.

Neuroophthalmology 2015 Oct 25;39(5):213-219. Epub 2015 Aug 25.

Department of Neurology, Kanazawa Medical University , Uchinada, Ishikawa, Japan.

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http://dx.doi.org/10.3109/01658107.2015.1072726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123140PMC
October 2015

Differences in the clinical features of two types of Vogt-Koyanagi-Harada disease: serous retinal detachment and optic disc swelling.

Jpn J Ophthalmol 2015 Mar 3;59(2):103-8. Epub 2014 Dec 3.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan,

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http://dx.doi.org/10.1007/s10384-014-0367-8DOI Listing
March 2015

Development and validation of new diagnostic criteria for acute retinal necrosis.

Jpn J Ophthalmol 2015 Jan 10;59(1):14-20. Epub 2014 Dec 10.

Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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http://dx.doi.org/10.1007/s10384-014-0362-0DOI Listing
January 2015

Profile of intraocular immune mediators in patients with age-related macular degeneration and the effect of intravitreal bevacizumab injection.

Retina 2014 Sep;34(9):1811-8

*Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan; and †Department of Ophthalmology, National Defense Medical College, Saitama, Japan.

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http://dx.doi.org/10.1097/IAE.0000000000000157DOI Listing
September 2014

A case of herpes zoster uveitis with severe hyphema.

BMC Ophthalmol 2014 May 29;14:74. Epub 2014 May 29.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1186/1471-2415-14-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046036PMC
May 2014

Behçet's disease ocular attack score 24: evaluation of ocular disease activity before and after initiation of infliximab.

Jpn J Ophthalmol 2014 Mar 31;58(2):120-30. Epub 2014 Jan 31.

Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan,

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http://dx.doi.org/10.1007/s10384-013-0294-0DOI Listing
March 2014

Prediction of severe cardiac involvement by fundus lesion in sarcoidosis.

Jpn J Ophthalmol 2014 Jan 12;58(1):81-5. Epub 2013 Nov 12.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

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http://dx.doi.org/10.1007/s10384-013-0288-yDOI Listing
January 2014

Peroxisome proliferator-activated receptor-γ agonist pioglitazone suppresses experimental autoimmune uveitis.

Exp Eye Res 2013 Nov 6;116:291-7. Epub 2013 Oct 6.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2013.09.017DOI Listing
November 2013

Suppression of experimental autoimmune optic neuritis by the novel agent fingolimod.

J Neuroophthalmol 2013 Jun;33(2):143-8

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1097/WNO.0b013e31828ea2fcDOI Listing
June 2013

[Optic neuritis--immunological approach to elucidate pathogenesis and develop innovative therapy].

Authors:
Takeshi Kezuka

Nippon Ganka Gakkai Zasshi 2013 Mar;117(3):270-91; discussion 292

Department of Ophthalmology, Tokyo Medical University, Japan.

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March 2013

Correlation of complement fragment C5a with inflammatory cytokines in the vitreous of patients with proliferative diabetic retinopathy.

Graefes Arch Clin Exp Ophthalmol 2013 Jan 21;251(1):15-7. Epub 2012 Apr 21.

Department of Ophthalmology, Tokyo Medical University, 6-7-1, Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1007/s00417-012-2024-6DOI Listing
January 2013

Visual functional and histopathological correlation in experimental autoimmune optic neuritis.

Invest Ophthalmol Vis Sci 2012 Oct 9;53(11):6964-71. Epub 2012 Oct 9.

Department of Ophthalmology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.12-10559DOI Listing
October 2012

Interleukin-10 gene-transfected mature dendritic cells suppress murine experimental autoimmune optic neuritis.

Invest Ophthalmol Vis Sci 2012 Oct 19;53(11):7235-45. Epub 2012 Oct 19.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.12-10587DOI Listing
October 2012

Intraocular VEGF level as a risk factor for postoperative complications after vitrectomy for proliferative diabetic retinopathy.

Invest Ophthalmol Vis Sci 2012 Sep 21;53(10):6403-10. Epub 2012 Sep 21.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.12-10367DOI Listing
September 2012

Suppression of murine experimental autoimmune optic neuritis by mature dendritic cells transfected with calcitonin gene-related Peptide gene.

Invest Ophthalmol Vis Sci 2012 Aug 13;53(9):5475-85. Epub 2012 Aug 13.

Department of Ophthalmology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.12-9935DOI Listing
August 2012

Relationship between NMO-antibody and anti-MOG antibody in optic neuritis.

J Neuroophthalmol 2012 Jun;32(2):107-10

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1097/WNO.0b013e31823c9b6cDOI Listing
June 2012

Costimulatory molecule expression on human uveal melanoma cells: functional analysis of CD40 and B7-H1.

Exp Eye Res 2012 Mar 20;96(1):98-106. Epub 2011 Dec 20.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1016/j.exer.2011.12.014DOI Listing
March 2012

Four cases of bilateral acute retinal necrosis with a long interval after the initial onset.

Br J Ophthalmol 2011 Sep 17;95(9):1251-4. Epub 2011 Jan 17.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjyuku, Shinjyuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1136/bjo.2010.191288DOI Listing
September 2011

Analysis of the pathogenesis of experimental autoimmune optic neuritis.

J Biomed Biotechnol 2011 25;2011:294046. Epub 2010 Oct 25.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1155/2011/294046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964037PMC
June 2011

Relation of intraocular concentrations of inflammatory factors and improvement of macular edema after vitrectomy in branch retinal vein occlusion.

Am J Ophthalmol 2011 Apr 22;151(4):610-616.e1. Epub 2011 Jan 22.

Department of Ophthalmology, Hachioji Medical Center of Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ajo.2010.09.030DOI Listing
April 2011

Expression and function of inducible costimulator on peripheral blood CD4+ T cells in Behçet's patients with uveitis: a new activity marker?

Invest Ophthalmol Vis Sci 2010 Oct 5;51(10):5099-104. Epub 2010 May 5.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.10-5286DOI Listing
October 2010

Human uveal melanoma cells inhibit the immunostimulatory function of dendritic cells.

Exp Eye Res 2010 Oct 17;91(4):491-9. Epub 2010 Jul 17.

Department of Ophthalmology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.exer.2010.06.025DOI Listing
October 2010

Immune responses to interphotoreceptor retinoid-binding protein and S-antigen in Behcet's patients with uveitis.

Invest Ophthalmol Vis Sci 2010 Jun 20;51(6):3067-75. Epub 2010 Jan 20.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.09-4313DOI Listing
June 2010

[Pars plana vitrectomy in patients with acute retinal necrosis syndrome: surgical results in 52 patients].

Nippon Ganka Gakkai Zasshi 2010 Apr;114(4):362-8

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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April 2010

Functional and morphological changes in the eyes of Behçet's patients with uveitis.

Acta Ophthalmol 2010 Mar 1;88(2):257-62. Epub 2009 Jun 1.

Department of Ophthalmology, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1755-3768.2009.01536.xDOI Listing
March 2010

Comparison of patients with ocular tuberculosis in the 1990s and the 2000s.

Jpn J Ophthalmol 2010 Jan 12;54(1):19-23. Epub 2010 Feb 12.

Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10384-009-0759-3DOI Listing
January 2010

Human iris pigment epithelial cells suppress T-cell activation via direct cell contact.

Exp Eye Res 2009 Sep 18;89(3):358-64. Epub 2009 Apr 18.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160 0023, Japan.

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http://dx.doi.org/10.1016/j.exer.2009.04.004DOI Listing
September 2009

Suppression of experimental autoimmune uveitis by angiotensin II type 1 receptor blocker telmisartan.

Invest Ophthalmol Vis Sci 2009 May 10;50(5):2255-61. Epub 2009 Jan 10.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.08-2649DOI Listing
May 2009

Suppression of experimental autoimmune uveoretinitis by regulatory dendritic cells in mice.

Arch Ophthalmol 2009 Apr;127(4):514-9

Department of Ophthalmology, Tokyo Medical University, 6-7-1, Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1001/archophthalmol.2009.34DOI Listing
April 2009

Human corneal endothelial cells expressing programmed death-ligand 1 (PD-L1) suppress PD-1+ T helper 1 cells by a contact-dependent mechanism.

Invest Ophthalmol Vis Sci 2009 Jan 4;50(1):263-72. Epub 2008 Sep 4.

Department of Ophthalmology & Visual Science, Tokyo Medical and Dental University Graduate School of Medicine, Tokyo, Japan.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.08-2536DOI Listing
January 2009

Circulating neutrophils in Behçet disease is resistant for apoptotic cell death in the remission phase of uveitis.

Graefes Arch Clin Exp Ophthalmol 2008 Feb 10;246(2):285-90. Epub 2007 Aug 10.

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00417-007-0659-5DOI Listing
February 2008

Functional expression of B7H1 on retinal pigment epithelial cells.

Exp Eye Res 2008 Jan 22;86(1):52-9. Epub 2007 Sep 22.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1016/j.exer.2007.09.007DOI Listing
January 2008

A case of lens-induced uveitis following metastatic endophthalmitis.

Jpn J Ophthalmol 2007 Jul-Aug;51(4):304-6. Epub 2007 Aug 3.

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http://dx.doi.org/10.1007/s10384-007-0446-1DOI Listing
October 2007

Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease.

Exp Eye Res 2007 May 20;84(5):823-31. Epub 2007 Jan 20.

Department of Bioregulation and Proteomics, Institute of Medical Science, St. Marianna University School of Medicine, 2-16-1 Sugao, Kawasaki, Kanagawa 216-8512, Japan.

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http://dx.doi.org/10.1016/j.exer.2007.01.003DOI Listing
May 2007

Acute retinal necrosis.

Chem Immunol Allergy 2007 ;92:244-253

Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan.

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https://www.karger.com/Article/FullText/99275
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http://dx.doi.org/10.1159/000099275DOI Listing
March 2007

Intravitreal injection of Tacrolimus (FK506) suppresses ongoing experimental autoimmune uveoretinitis in Rats.

Br J Ophthalmol 2007 Feb 20;91(2):237-42. Epub 2006 Sep 20.

Department of Ophthalmology, Tokyo Medical University, 6-7-1, Nishi-shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1136/bjo.2006.103168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857637PMC
February 2007

Possibility of inducing anterior chamber-associated immune deviation by TGF-beta2 treatment of monocytes isolated from Behcet's patients.

Exp Eye Res 2006 Oct 5;83(4):981-8. Epub 2006 Jul 5.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1016/j.exer.2006.05.005DOI Listing
October 2006

Induction of eye-derived tolerance does not depend on naturally occurring CD4+CD25+ T regulatory cells.

Invest Ophthalmol Vis Sci 2006 Mar;47(3):1047-55

Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1167/iovs.05-0110DOI Listing
March 2006

Risk and prognostic factors of poor visual outcome in Behcet's disease with ocular involvement.

Graefes Arch Clin Exp Ophthalmol 2005 Nov 28;243(11):1147-52. Epub 2005 Jun 28.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku Shinjuku-Ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1007/s00417-005-0005-8DOI Listing
November 2005

Ocular complications in myelodysplastic syndromes as preleukemic disorders.

Jpn J Ophthalmol 2005 Sep-Oct;49(5):377-83

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10384-005-0228-6DOI Listing
October 2005

Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.

Int Immunol 2005 May 18;17(5):523-30. Epub 2005 Mar 18.

Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

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http://dx.doi.org/10.1093/intimm/dxh234DOI Listing
May 2005

[Ocular inflammation with varicella-zoster virus and immune privilege].

Authors:
Takeshi Kezuka

Nippon Ganka Gakkai Zasshi 2004 Nov;108(11):649-53

Department of Ophthalmology, Tokyo Medical University, Japan.

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November 2004

Prevention of experimental autoimmune uveoretinitis by vasoactive intestinal peptide.

Arch Ophthalmol 2004 Aug;122(8):1179-84

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1001/archopht.122.8.1179DOI Listing
August 2004

Immune responses to retinal self-antigens in CD25(+)CD4(+) regulatory T-cell-depleted mice.

Invest Ophthalmol Vis Sci 2004 Jun;45(6):1879-86

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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http://dx.doi.org/10.1167/iovs.02-1030DOI Listing
June 2004

Immune deviation and ocular infections with varicella zoster virus.

Authors:
Takeshi Kezuka

Ocul Immunol Inflamm 2004 Mar;12(1):17-24

Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.

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March 2004

Chemokine and chemokine receptor expression during experimental autoimmune uveoretinitis in mice.

Graefes Arch Clin Exp Ophthalmol 2003 Feb 28;241(2):111-5. Epub 2003 Jan 28.

Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1007/s00417-002-0556-xDOI Listing
February 2003

A relationship between varicella-zoster virus-specific delayed hypersensitivity and varicella-zoster virus-induced anterior uveitis.

Arch Ophthalmol 2002 Sep;120(9):1183-8

Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University, 1163, Tate-machi, Hachioji-city, Tokyo, 193-8639, Japan.

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http://dx.doi.org/10.1001/archopht.120.9.1183DOI Listing
September 2002

The eye's view of antigen presentation.

Hum Immunol 2002 Jun;63(6):435-43

Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/s0198-8859(02)00393-2DOI Listing
June 2002