Takeshi Ikeuchi

Takeshi Ikeuchi

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[Exploring Therapeutic Targets for Alzheimer's Disease by Comprehensive Genetic Analysis].

Authors:
Takeshi Ikeuchi

Brain Nerve 2019 Oct;71(10):1081-1088

Department of Molecular Genetics, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.11477/mf.1416201407DOI Listing
October 2019

Enhancer variants associated with Alzheimer's disease affect gene expression via chromatin looping.

BMC Med Genomics 2019 09 9;12(1):128. Epub 2019 Sep 9.

Department of Genome Informatics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1186/s12920-019-0574-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734281PMC
September 2019

Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson's disease.

BMC Neurol 2019 Jun 4;19(1):113. Epub 2019 Jun 4.

Department of Neurology, School of Medicine, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.

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http://dx.doi.org/10.1186/s12883-019-1346-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549316PMC
June 2019

Remarkable behavioural signs and progressive non-fluent aphasia in a patient with adult-onset leucoencephalopathy with axonal spheroids and pigmented glia.

Psychogeriatrics 2019 May 4;19(3):282-285. Epub 2018 Nov 4.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.

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http://doi.wiley.com/10.1111/psyg.12387
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http://dx.doi.org/10.1111/psyg.12387DOI Listing
May 2019

Globular glial tauopathy Type II: Clinicopathological study of two autopsy cases.

Neuropathology 2019 Apr 15;39(2):111-119. Epub 2019 Jan 15.

Department of Pathology, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1111/neup.12532DOI Listing
April 2019

Cerebral hemorrhagic stroke associated with cerebral amyloid angiopathy in young adults about 3 decades after neurosurgeries in their infancy.

J Neurol Sci 2019 Apr 1;399:3-5. Epub 2019 Feb 1.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.01.051DOI Listing
April 2019

Low serum 25-hydroxyvitamin D increases cognitive impairment in elderly people.

J Bone Miner Metab 2019 Mar 14;37(2):368-375. Epub 2018 Jun 14.

Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1007/s00774-018-0934-zDOI Listing
March 2019

Soluble LR11 competes with amyloid β in binding to cerebrospinal fluid-high-density lipoprotein.

Clin Chim Acta 2019 Feb 15;489:29-34. Epub 2018 Nov 15.

Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan; Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan.

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http://dx.doi.org/10.1016/j.cca.2018.11.024DOI Listing
February 2019

Young adult-onset, very slowly progressive cognitive decline with spastic paraparesis in Alzheimer's disease with cotton wool plaques due to a novel presenilin1 G417S mutation.

Acta Neuropathol Commun 2019 02 12;7(1):19. Epub 2019 Feb 12.

Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan.

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http://dx.doi.org/10.1186/s40478-019-0672-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371429PMC
February 2019

Molecular Network Analysis of the Urinary Proteome of Alzheimer's Disease Patients.

Dement Geriatr Cogn Dis Extra 2019 Jan-Apr;9(1):53-65. Epub 2019 Feb 8.

Biofluid Biomarker Center, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1159/000496100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477484PMC
February 2019

-related leukoencephalopathy: A major player in primary microgliopathies.

Neurology 2018 12 14;91(24):1092-1104. Epub 2018 Nov 14.

From the Departments of Neurology (T.K., Z.K.W.) and Neuroscience (K.K., D.W.D.), Mayo Clinic, Jacksonville, FL; and Department of Molecular Genetics (T.I.), Brain Research Institute, Niigata University, Niigata, Japan. Dr. Konno is currently with the Department of Neurology, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000006642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329328PMC
December 2018

Duplication and deletion upstream of in autosomal dominant adult-onset leukodystrophy.

Neurol Genet 2018 Dec 7;4(6):e292. Epub 2018 Dec 7.

Department of Molecular Genetics (N.M., T.M., T. Ishiguro, K. Kasuga, T. Ikeuchi) and Department of Neurology (N.M., T.M., T. Ishiguro, T.K., O.O.), Brain Research Institute, Niigata University; Department of Neurology (K.O., S.K., Y.O.), Juntendo University Shizuoka Hospital; Division of Neurology, Department of Internal Medicine (M.E., N.S., H.H.), Faculty of Medicine, Saga University; Department of Neurology (Y.M., R.Y., J.-I.K.), Neurological Institute, Graduate School of Medical Sciences, Kyushu University; Department of Neurology (K. Komatsu, H.Y.), Kitano Hospital, The Tazuke Kofukai Medical Research Institute; and Medical Technology (H.N.), Graduate School of Health Sciences, Niigata University.

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http://dx.doi.org/10.1212/NXG.0000000000000292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340331PMC
December 2018

Clinical and cognitive characteristics of preclinical Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative cohort.

Alzheimers Dement (N Y) 2018 26;4:645-651. Epub 2018 Nov 26.

Unit for Early and Exploratory Clinical Development, The University of Tokyo Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.trci.2018.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258138PMC
November 2018

A novel presenilin 1 mutation (Leu418Trp) associated with spasticity, parkinsonism, and white matter lesion in a dominant Alzheimer's family.

J Neurol Sci 2018 04 5;387:166-169. Epub 2018 Jan 5.

Departments of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.01.006DOI Listing
April 2018

Familial and sporadic chronic progressive degenerative parietal ataxia.

J Neurol Sci 2018 04 31;387:70-74. Epub 2018 Jan 31.

Department of Neurology, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho Kita-ku, Okayama 700-8558, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.01.031DOI Listing
April 2018

Cognitive dysfunction and symptoms of movement disorders in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia.

Parkinsonism Relat Disord 2018 Jan 16;46 Suppl 1:S39-S41. Epub 2017 Aug 16.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2017.08.018DOI Listing
January 2018

Association between dialysis treatment and cognitive decline: A study from the Project in Sado for Total Health (PROST), Japan.

Geriatr Gerontol Int 2017 Oct 21;17(10):1584-1587. Epub 2016 Nov 21.

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1111/ggi.12937DOI Listing
October 2017

Semagacestat Is a Pseudo-Inhibitor of γ-Secretase.

Cell Rep 2017 Oct;21(1):259-273

Neuropsychiatry, Department of Integrated Medicine, Division of Internal Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.09.032DOI Listing
October 2017

A novel frameshift GRN mutation results in frontotemporal lobar degeneration with a distinct clinical phenotype in two siblings: case report and literature review.

BMC Neurol 2017 Sep 15;17(1):182. Epub 2017 Sep 15.

Department of the Neurology, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Ten'noudai, Tsukuba, Ibaraki, 305-8575, Japan.

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http://dx.doi.org/10.1186/s12883-017-0959-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603021PMC
September 2017

Longitudinal clinical and neuro-radiological findings in a patient with leukoencephalopathy with brain calcifications and cysts (Labrune syndrome).

eNeurologicalSci 2017 Sep 21;8:28-30. Epub 2017 Jul 21.

Department of Neuropathology, Institute for Medical Science of Aging, Aichi Medical University, 1-1 Yazakokarimata, Nagakute 480-1195, Japan.

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http://dx.doi.org/10.1016/j.ensci.2017.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730894PMC
September 2017

[Emerging Therapeutic Targets Revealed by Genome Analysis in Alzheimer's Disease].

Authors:
Takeshi Ikeuchi

Brain Nerve 2017 Jul;69(7):789-798

Department of Molecular Genetics, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.11477/mf.1416200822DOI Listing
July 2017

Effects of super-hard rice bread blended with black rice bran on amyloid β peptide production and abrupt increase in postprandial blood glucose levels in mice.

Biosci Biotechnol Biochem 2017 Feb 4;81(2):323-334. Epub 2016 Oct 4.

a Faculty of Applied Life Sciences , Niigata University of Pharmacy and Applied Life Sciences , Niigata , Japan.

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http://dx.doi.org/10.1080/09168451.2016.1240605DOI Listing
February 2017

Co-existence of spastic paraplegia-30 with novel KIF1A mutation and spinocerebellar ataxia 31 with intronic expansion of BEAN and TK2 in a family.

J Neurol Sci 2017 Jan 15;372:128-130. Epub 2016 Nov 15.

Department of Molecular Genetics, Bioresource Science Branch, Center for Bioresources, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan.

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http://dx.doi.org/10.1016/j.jns.2016.11.032DOI Listing
January 2017

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease.

Acta Neuropathol Commun 2017 Jan 31;5(1):10. Epub 2017 Jan 31.

Department of Molecular Genetics, Bioresource Science Branch, Center for Bioresources, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1186/s40478-017-0414-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282710PMC
January 2017

Familial idiopathic basal ganglia calcification: Histopathologic features of an autopsied patient with an SLC20A2 mutation.

Neuropathology 2016 Aug 4;36(4):365-71. Epub 2015 Dec 4.

Departments of Pathology, Brain Research Institute, University of Niigata, Niigata, Japan.

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http://dx.doi.org/10.1111/neup.12280DOI Listing
August 2016

Modifiable Factors Associated with Cognitive Impairment in 1,143 Japanese Outpatients: The Project in Sado for Total Health (PROST).

Dement Geriatr Cogn Dis Extra 2016 May-Aug;6(2):341-349. Epub 2016 Aug 12.

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1159/000447963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040930PMC
August 2016

[Multifunctional Roles of APOE in Alzheimer's Disease Pathogenesis].

Brain Nerve 2016 Jul;68(7):703-12

Department of Neurology, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.11477/mf.1416200498DOI Listing
July 2016

Elevated C-Reactive Protein Is Associated with Cognitive Decline in Outpatients of a General Hospital: The Project in Sado for Total Health (PROST).

Dement Geriatr Cogn Dis Extra 2016 Jan-Apr;6(1):10-9. Epub 2016 Jan 19.

Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, University of Niigata, Niigata, Japan.

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http://dx.doi.org/10.1159/000442585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772636PMC
March 2016

Reduced CSF Water Influx in Alzheimer's Disease Supporting the β-Amyloid Clearance Hypothesis.

PLoS One 2015 6;10(5):e0123708. Epub 2015 May 6.

Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata, Niigata, Japan; Department of Neurology, University of California Davis, Davis, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123708PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422624PMC
February 2016

[Clinical and neuroimaging characteristics of patients with hereditary diffuse leukoencephalopathy with spheroids (HDLS)].

Authors:
Takeshi Ikeuchi

Rinsho Shinkeigaku 2014 ;54(12):1158-61

Department of Molecular Genetics, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.5692/clinicalneurol.54.1158DOI Listing
October 2015

Variable expression of microglial DAP12 and TREM2 genes in Nasu-Hakola disease.

Neurogenetics 2015 Oct 23;16(4):265-76. Epub 2015 May 23.

Department of Pathology, Saitama Medical University, 38 Morohongo, Iruma, Saitama, 350-0495, Japan.

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http://dx.doi.org/10.1007/s10048-015-0451-3DOI Listing
October 2015

Systematic review and meta-analysis of Japanese familial Alzheimer's disease and FTDP-17.

J Hum Genet 2015 May 19;60(5):281-3. Epub 2015 Feb 19.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1038/jhg.2015.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521293PMC
May 2015

Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease.

Alzheimers Dement (Amst) 2015 Mar 29;1(1):67-74. Epub 2015 Mar 29.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1016/j.dadm.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876914PMC
March 2015

ApoE-isoform-dependent cellular uptake of amyloid-β is mediated by lipoprotein receptor LR11/SorLA.

Biochem Biophys Res Commun 2015 Jan 5;456(1):482-8. Epub 2014 Dec 5.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.11.111DOI Listing
January 2015

Relative ratio and level of amyloid-β 42 surrogate in cerebrospinal fluid of familial Alzheimer disease patients with presenilin 1 mutations.

Neurodegener Dis 2014 30;13(2-3):166-70. Epub 2013 Oct 30.

Neuropsychiatry and Neurochemistry, Division of Internal Medicine, Department of Integrated Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1159/000355258DOI Listing
September 2014

[Alzheimer's Disease Cooperative Study (ADCS)].

Brain Nerve 2014 Jun;66(6):691-8

Department of Neuroscience, Graduate School of Medicine, Osaka City University.

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June 2014

[Adult-onset hereditary leukoencephalopathy: classification and molecular basis of the disorder].

Authors:
Takeshi Ikeuchi

Rinsho Shinkeigaku 2012 ;52(11):1386-9

Department of Neurology, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.5692/clinicalneurol.52.1386DOI Listing
April 2014

Clinical and neuroimaging features of patient with early-onset Parkinson's disease with dementia carrying SNCA p.G51D mutation.

Parkinsonism Relat Disord 2014 Feb 20;20(2):262-4. Epub 2013 Nov 20.

Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2013.11.008DOI Listing
February 2014

A Japanese family with idiopathic basal ganglia calcification with novel SLC20A2 mutation presenting with late-onset hallucination and delusion.

J Neurol 2014 Jan 10;261(1):242-4. Epub 2013 Dec 10.

Department of Neurology, Brain Research Institute, Niigata University, 1 Asahimachi, Chuo-ku, Niigata, 951-8585, Japan,

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http://dx.doi.org/10.1007/s00415-013-7205-7DOI Listing
January 2014

Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.

Neurology 2014 Jan 13;82(2):139-48. Epub 2013 Dec 13.

From the Departments of Neurology (T.K., Masayoshi Tada, A. Koyama, H.N., M.A., A.I., M.N., T. Ikeuchi), Pathology (Mari Tada, K.O., H.T., A. Kakita), Molecular Neuroscience (O.O.), and Molecular Genetics, Brain Research Institute (T. Ikeuchi), Niigata University; Department of Neurology (Y.H.), Maebashi Red Cross Hospital; Department of Neurology (J.N.), Gyotoku General Hospital, Ichikawa; Department of Neurology (A.M., M.Y.), University of Fukui Hospital; Department of Neurology and Geriatrics (N.Y., T. Inuzuka), Gifu University Graduate School of Medicine; Department of Neurology (K. Ishihara, M.K.), Showa University School of Medicine, Tokyo; Department of Human Pathology (H.Y.), Gunma University Graduate School of Medicine, Maebashi; and the Department of Pathology and Applied Neurobiology (K. Itoh), Kyoto Prefectural University of Medicine, Japan.

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http://dx.doi.org/10.1212/WNL.0000000000000046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937843PMC
January 2014

Sporadic ALS with compound heterozygous mutations in the SQSTM1 gene.

Acta Neuropathol 2013 Sep 28;126(3):453-9. Epub 2013 Jun 28.

Department of Pathology, Brain Research Institute, University of Niigata, 1-757 Asahimachi, Chuo-ku, Niigata, 951-8585, Japan.

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http://dx.doi.org/10.1007/s00401-013-1150-5DOI Listing
September 2013

Novel G37V mutation of SOD1 gene in autopsied patient with familial amyotrophic lateral sclerosis.

Amyotroph Lateral Scler 2012 Oct 7;13(6):570-2. Epub 2012 Jun 7.

Department of Neurology, Tokyo Metropolitan Neurological Hospital, Japan.

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http://dx.doi.org/10.3109/17482968.2012.686512DOI Listing
October 2012

α-Synuclein as CSF and Blood Biomarker of Dementia with Lewy Bodies.

Int J Alzheimers Dis 2012 26;2012:437025. Epub 2012 Sep 26.

Department of Neurology, Brain Research Institute, Niigata University, Niigata 951-8585, Japan ; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA 92093, USA.

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http://dx.doi.org/10.1155/2012/437025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463927PMC
October 2012

[Cerebrospinal fluid and plasma biomarkers for dementia with lewy bodies].

Brain Nerve 2012 May;64(5):505-13

Department of Neurosciences, University of California, San Diego, CA, USA.

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May 2012

[Progranulin].

Nihon Rinsho 2011 Oct;69 Suppl 8:103-9

Department of Neurology, Brain Research Institute, Niigata University.

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October 2011

Genotype-phenotype correlations in early onset ataxia with ocular motor apraxia and hypoalbuminaemia.

Brain 2011 May 12;134(Pt 5):1387-99. Epub 2011 Apr 12.

Department of Neurology, Clinical Neuroscience Branch, Brain Research Institute, Niigata University, 1-757 Asahimachi-dori, Chuo-ku, Niigata-City, Niigata 951-8585, Japan.

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http://dx.doi.org/10.1093/brain/awr069DOI Listing
May 2011

Increased levels of soluble LR11 in cerebrospinal fluid of patients with Alzheimer disease.

Dement Geriatr Cogn Disord 2010 30;30(1):28-32. Epub 2010 Jul 30.

Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Niigata, Japan.

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http://dx.doi.org/10.1159/000315539DOI Listing
December 2010

Involvement of Onuf's nucleus in Machado-Joseph disease: a morphometric and immunohistochemical study.

Acta Neuropathol 2010 Oct 26;120(4):439-48. Epub 2010 May 26.

Department of Pathology, Brain Research Institute, University of Niigata, Chuo-ku, Niigata 951-8585, Japan.

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http://dx.doi.org/10.1007/s00401-010-0699-5DOI Listing
October 2010

[A case of amyotrophic lateral sclerosis/frontotemporal lobar degeneration with apraxia of eyelid opening].

Rinsho Shinkeigaku 2010 Sep;50(9):645-50

Department of Neurology, Brain Research Institute, Niigata University.

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http://dx.doi.org/10.5692/clinicalneurol.50.645DOI Listing
September 2010

Long-term disability and prognosis in dentatorubral-pallidoluysian atrophy: a correlation with CAG repeat length.

Mov Disord 2010 Aug;25(11):1694-700

Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Chuo-ku, Niigata, Japan.

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http://dx.doi.org/10.1002/mds.23167DOI Listing
August 2010

Differential levels of alpha-synuclein, beta-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease.

J Neurol Neurosurg Psychiatry 2010 Jun;81(6):608-10

Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Asahimachi 1-757, Chuo-ku, Niigata 951-8585, Japan.

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http://dx.doi.org/10.1136/jnnp.2009.197483DOI Listing
June 2010

Alzheimer's disease: report of two autopsy cases with a clinical diagnosis of corticobasal degeneration.

Neuropathology 2010 Apr 22;30(2):140-8. Epub 2009 Sep 22.

Department of Pathology, Brain Research Institute, University of Niigata, Niigata, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2009.01062.xDOI Listing
April 2010

Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado-Joseph disease.

Acta Neuropathol 2009 Oct 13;118(4):553-60. Epub 2009 Jun 13.

Department of Pathology, Brain Research Institute, University of Niigata, 1-757 Asahimachi, Niigata, Japan.

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http://dx.doi.org/10.1007/s00401-009-0552-xDOI Listing
October 2009

Prevention of stroke and dementia by statin therapy: experimental and clinical evidence of their pleiotropic effects.

Pharmacol Ther 2007 Feb 16;113(2):378-93. Epub 2006 Nov 16.

Division of Clinical Preventive Medicine, Department of Community Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.

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http://dx.doi.org/10.1016/j.pharmthera.2006.09.003DOI Listing
February 2007

A possible variant of neuro-Behçet disease presenting chronic progressive ataxia without mucocutaneo-ocular symptoms.

Rheumatol Int 2006 Nov 25;27(1):61-5. Epub 2006 Aug 25.

Department of Neurology, Brain Research Institute, Niigata University, 1 Asahimachi, Niigata , 951-8585, Japan.

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http://dx.doi.org/10.1007/s00296-006-0171-yDOI Listing
November 2006

Can statin therapy really reduce the risk of Alzheimer's disease and slow its progression?

Curr Opin Lipidol 2005 Dec;16(6):619-23

Division of Clinical Preventive Medicine, Department of Community Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1097/01.hjh.0000191246.68443.ffDOI Listing
December 2005