Takayuki Yoshino

Takayuki Yoshino

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Takayuki Yoshino

Publications by authors named "Takayuki Yoshino"

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Sleep Disturbance Worsens Lower Urinary Tract Symptoms: The Nagahama Study.

J Urol 2019 08 8;202(2):354. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://dx.doi.org/10.1097/JU.0000000000000212DOI Listing
August 2019

Reply by Authors.

J Urol 2019 08 8;202(2):360-361. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://dx.doi.org/10.1097/01.JU.0000559826.09631.1dDOI Listing
August 2019

Predictive factors for hyperprogressive disease during nivolumab as anti-PD1 treatment in patients with advanced gastric cancer.

Gastric Cancer 2019 07 9;22(4):793-802. Epub 2019 Jan 9.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s10120-018-00922-8DOI Listing
July 2019

HER2-targeted therapy should be shifted towards an earlier line for patients with anti-EGFR-therapy naïve, -amplified metastatic colorectal cancer.

ESMO Open 2019 8;4(3):e000530. Epub 2019 Jul 8.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1136/esmoopen-2019-000530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615873PMC
July 2019

A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer.

Br J Cancer 2019 May 24;120(10):982-986. Epub 2019 Apr 24.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1038/s41416-019-0457-yDOI Listing
May 2019

Third- or Later-line Therapy for Metastatic Colorectal Cancer: Reviewing Best Practice.

Clin Colorectal Cancer 2019 03 16;18(1):e117-e129. Epub 2018 Nov 16.

Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2018.11.002DOI Listing
March 2019

Comparative sequence analysis of patient-matched primary colorectal cancer, metastatic, and recurrent metastatic tumors after adjuvant FOLFOX chemotherapy.

BMC Cancer 2019 Mar 21;19(1):255. Epub 2019 Mar 21.

Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1186/s12885-019-5479-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429751PMC
March 2019

Clinical Utility of Analyzing Circulating Tumor DNA in Patients with Metastatic Colorectal Cancer.

Oncologist 2018 Nov 26;23(11):1310-1318. Epub 2018 Apr 26.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan

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http://dx.doi.org/10.1634/theoncologist.2017-0621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291328PMC
November 2018

Utility of the quasi-monomorphic variation range in unresectable metastatic colorectal cancer patients.

Cancer Sci 2018 Nov 2;109(11):3411-3415. Epub 2018 Oct 2.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://doi.wiley.com/10.1111/cas.13774
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http://dx.doi.org/10.1111/cas.13774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215873PMC
November 2018

[MSI Status in Colorectal Cancer].

Gan To Kagaku Ryoho 2018 Nov;45(11):1567-1572

Dept. of Gastrointestinal Oncology, National Cancer Center Hospital East.

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November 2018

Prognostic and Predictive Value of HER2 Amplification in Patients With Metastatic Colorectal Cancer.

Clin Colorectal Cancer 2018 09 19;17(3):198-205. Epub 2018 May 19.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2018.05.006DOI Listing
September 2018

Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers.

Oncogene 2018 03 19;37(13):1775-1787. Epub 2018 Jan 19.

Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Ishikawa, Japan.

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http://dx.doi.org/10.1038/s41388-017-0035-9DOI Listing
March 2018

Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.

N Engl J Med 2018 Mar;378(13):1177-1188

From the Divisions of Medical Oncology (A.G.) and Biomedical Statistics and Informatics (Q.S., J.P.M., L.A.R., D.J.S.), Mayo Clinic, Rochester, MN; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Martino-IST, Genoa (A.F. Sobrero), Ospedale Papa Giovanni XXIII, Bergamo (R.L.), and IRCCS Mario Negri Institute for Pharmacological Research, Milan (V.T.) - all in Italy; Karmanos Cancer Institute, Wayne State University, Detroit (A.F. Shields); National Cancer Center Hospital East, Chiba (T. Yoshino), Yokohama City University School of Medicine, Yokohama (T. Yamanaka), and the University of Tokyo, Tokyo (T.W.) - all in Japan; the Institute of Cancer Sciences, University of Glasgow, Glasgow (J.P.), the University of Oxford, Oxford (R.K.), Christie Hospital, Manchester (M.S.), and University Hospital Southampton, Southampton (T.I.) - all in the United Kingdom; Hôpital Européen Georges-Pompidou, Sorbonne Paris Cite/Paris Descartes University (J.T.), and Saint-Antoine Hospital and Sorbonne Universités, Pierre and Marie Curie University-Paris 6 (T.A.), Paris, and Methodology and Quality of Life Unit, INSERM Unité 1098, Besançon (D.V.) - all in France; the Department of Medical Oncology, University Hospital of Heraklion, Faculty of Medicine, University of Crete, Heraklion (J.S.), and Bioclinic Thessaloniki, Thessaloniki (I.B.) - both in Greece; Dana-Farber Cancer Institute, Boston (J.A.M.); and Duke Cancer Institute, Durham, NC (D.N.).

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http://dx.doi.org/10.1056/NEJMoa1713709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426127PMC
March 2018

Integrated safety summary for trifluridine/tipiracil (TAS-102).

Anticancer Drugs 2018 01;29(1):89-96

Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1097/CAD.0000000000000554DOI Listing
January 2018

A retrospective study of the safety and efficacy of paclitaxel plus ramucirumab in patients with advanced or recurrent gastric cancer with ascites.

BMC Cancer 2018 01 31;18(1):120. Epub 2018 Jan 31.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1186/s12885-018-4057-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793350PMC
January 2018

Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma.

J Cancer Res Clin Oncol 2017 Nov 29;143(11):2351-2361. Epub 2017 Jul 29.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-017-2482-7DOI Listing
November 2017

A Proposal for Progression-Free Survival Assessment in Patients with Early Progressive Cancer.

Anticancer Res 2017 10;37(10):5851-5855

National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.21873/anticanres.12029DOI Listing
October 2017

Targeting of super-enhancers and mutant BRAF can suppress growth of BRAF-mutant colon cancer cells via repression of MAPK signaling pathway.

Cancer Lett 2017 08 31;402:100-109. Epub 2017 May 31.

Division of Epigenomics, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.05.017DOI Listing
August 2017

[Current Status and Future Perspectives of SCRUM-Japan].

Gan To Kagaku Ryoho 2017 Aug;44(8):621-626

National Cancer Center Hospital East.

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August 2017

Baseline carcinoembryonic antigen as a predictive factor of ramucirumab efficacy in RAISE, a second-line metastatic colorectal carcinoma phase III trial.

Eur J Cancer 2017 06 13;78:61-69. Epub 2017 Apr 13.

Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ejca.2017.03.007DOI Listing
June 2017

Analysis of esophagogastric cancer patients enrolled in the National Cancer Institute Cancer Therapy Evaluation Program sponsored phase 1 trials.

Gastric Cancer 2017 May 10;20(3):481-488. Epub 2016 Aug 10.

Investigational Drug Branch, Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, 9609 Medical Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s10120-016-0629-xDOI Listing
May 2017

Clinicopathological features of programmed death ligand 1 expression with tumor-infiltrating lymphocyte, mismatch repair, and Epstein-Barr virus status in a large cohort of gastric cancer patients.

Gastric Cancer 2017 May 14;20(3):407-415. Epub 2016 Sep 14.

Division of Pathology, Research Cancer for Innovative Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s10120-016-0631-3DOI Listing
May 2017

A Phase I study of intravenous PI3K inhibitor copanlisib in Japanese patients with advanced or refractory solid tumors.

Cancer Chemother Pharmacol 2017 Jan 3;79(1):89-98. Epub 2016 Dec 3.

National Cancer Center Hospital East, 5-1, Kashiwanoha 6-chome, Kashiwa-shi, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00280-016-3198-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225172PMC
January 2017

Phase I clinical and pharmacokinetic study of S-1 plus oral leucovorin in patients with metastatic colorectal cancer.

Cancer Chemother Pharmacol 2017 Jan 8;79(1):107-116. Epub 2016 Dec 8.

Department of Gastrointestinal Oncology, National Cancer Institute Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00280-016-3212-6DOI Listing
January 2017

Concordance between PIK3CA mutations in endoscopic biopsy and surgically resected specimens of esophageal squamous cell carcinoma.

BMC Cancer 2017 01 9;17(1):36. Epub 2017 Jan 9.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://bmccancer.biomedcentral.com/articles/10.1186/s12885-0
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http://dx.doi.org/10.1186/s12885-016-3041-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220610PMC
January 2017

TAS-102 Safety in Metastatic Colorectal Cancer: Results From the First Postmarketing Surveillance Study.

Clin Colorectal Cancer 2016 12 17;15(4):e205-e211. Epub 2016 May 17.

Department of Clinical Oncology and Outpatient Treatment Center, Aichi Cancer Center Hospital, Aichi, Japan.

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http://dx.doi.org/10.1016/j.clcc.2016.04.004DOI Listing
December 2016

Feasibility of classical secondary hormonal therapies prior to docetaxel therapy in Japanese patients with castration-resistant prostate cancer: Multicenter retrospective study.

Prostate Int 2016 Dec 20;4(4):140-144. Epub 2016 Sep 20.

Department of Urology, Ibaraki Prefectural Central Hospital, Kasama, Japan; Department of Urology, Ibaraki Clinical Education and Training Center, Faculty of Medicine, University of Tsukuba, Japan.

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http://dx.doi.org/10.1016/j.prnil.2016.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153431PMC
December 2016

Gastrointestinal Perforation and Fistula Formation in 5 Patients With Colorectal Cancer During Treatment With Regorafenib.

Clin Colorectal Cancer 2016 Dec 28. Epub 2016 Dec 28.

Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.clcc.2016.11.003DOI Listing
December 2016

Integration of clinical information and molecular biology profile -Endeavor of SCRUM-Japan-.

Nihon Rinsho 2016 11;74(11):1812-1817

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November 2016

Clinical outcomes of patients with gastrointestinal stromal tumor in phase I clinical trials.

BMC Cancer 2016 11 14;16(1):889. Epub 2016 Nov 14.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East (NCCHE), 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1186/s12885-016-2939-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109764PMC
November 2016

The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer.

Cancer Res 2016 11;76(22):6443-6444

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2867DOI Listing
November 2016

12-Gene Recurrence Score Assay Stratifies the Recurrence Risk in Stage II/III Colon Cancer With Surgery Alone: The SUNRISE Study.

J Clin Oncol 2016 08 20;34(24):2906-13. Epub 2016 Jun 20.

Takeharu Yamanaka, National Cancer Center; Atsushi Ochiai, Atsushi Ohtsu, and Takayuki Yoshino, National Cancer Center Hospital East Chiba, Japan; Takeharu Yamanaka, Yokohama City University, Yokohama; Eiji Oki, Kyushu University; Tetsuya Kusumoto, National Kyushu Medical Center, Fukuoka; Kentaro Yamazaki, Shizuoka Cancer Center, Shizuoka; Kensei Yamaguchi and Kiwamu Akagi, Saitama Cancer Center, Saitama; Kensei Yamaguchi, Cancer Institute Hospital of Japanese Foundation for Cancer Research; Hiroyuki Uetake, Tokyo Medical and Dental University; Yasuo Ohashi, Chuo University, Tokyo; Kei Muro, Aichi Cancer Center Hospital, Nagoya; Takeo Sato, Kitasato University School of Medicine, Kanagawa; Tomohiro Nishina, National Hospital Organization Shikoku Cancer Center, Matsuyama; Masataka Ikeda, Osaka National Hospital; Akiyoshi Kanazawa, Kitano Hospital, Osaka; Takeshi Kato, Kansai Rosai Hospital, Amagasaki, Japan; Calvin Chao, Margarita Lopatin, Jayadevi Krishnakumar, and Helen Bailey, Genomic Health, Redwood City, CA

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http://dx.doi.org/10.1200/JCO.2016.67.0414DOI Listing
August 2016

A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.

Cancer Chemother Pharmacol 2016 06 30;77(6):1253-62. Epub 2016 Apr 30.

Department Gastrointestinal Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa-shi, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00280-016-3041-7DOI Listing
June 2016

Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.

Cancer Sci 2016 May 28;107(5):659-65. Epub 2016 Mar 28.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1111/cas.12912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970833PMC
May 2016

Prognostic significance of tumor regression grade for patients with esophageal squamous cell carcinoma after neoadjuvant chemotherapy followed by surgery.

J Surg Oncol 2016 Mar 12;113(4):390-6. Epub 2016 Jan 12.

Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1002/jso.24151DOI Listing
March 2016

[A Case of Advanced Seminoma in a 79-Year-Old Man Successfully Treated with Etoposide and Cisplatin].

Hinyokika Kiyo 2015 Dec;61(12):515-8

The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.

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December 2015

Phase I study of LY2603618, a CHK1 inhibitor, in combination with gemcitabine in Japanese patients with solid tumors.

Anticancer Drugs 2015 Nov;26(10):1043-53

aDepartment of Gastrointestinal Oncology bDepartment of Breast and Medical Oncology, National Cancer Center Hospital East, Kashiwa, Chiba cEli Lilly Japan K.K., Kobe, Japan dEli Lilly and Company, Indianapolis, Indiana, USA.

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http://dx.doi.org/10.1097/CAD.0000000000000278DOI Listing
November 2015

Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer.

Invest New Drugs 2015 Oct 12;33(5):1068-77. Epub 2015 Jul 12.

Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s10637-015-0271-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768213PMC
October 2015

A phase II study of S-1, oxaliplatin, oral leucovorin, and bevacizumab combination therapy (SOLA) in patients with unresectable metastatic colorectal cancer.

Cancer Chemother Pharmacol 2015 Sep 22;76(3):547-53. Epub 2015 Jul 22.

Department of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, 160 Minami Umemoto-machi Kou, Matsuyama, 791-0280, Japan,

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http://link.springer.com/content/pdf/10.1007%2Fs00280-015-28
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http://link.springer.com/10.1007/s00280-015-2825-5
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http://dx.doi.org/10.1007/s00280-015-2825-5DOI Listing
September 2015

Randomized trial of TAS-102 for refractory metastatic colorectal cancer.

N Engl J Med 2015 May;372(20):1909-19

From the Dana-Farber Cancer Institute, Boston (R.J.M, J.M.C.); University Hospitals, Leuven and KU Leuven, Leuven (E.V.C., H.P.), and Universitaire Ziekenhuizen Antwerp, Edegem (M.P.) - all in Belgium; University of Pisa, Pisa (A.F.), IRCCS Azienda Ospedaliera Universitaria San Martino-Istituto Nazionale per la Ricerca Sul Cancro, Genoa (A.S.), and the Fondazione Poliambulanza Istituto Ospedaliero, Brescia (A.Z.) - all in Italy; National Cancer Center Hospital East, Chiba (T.Y., A.O.), Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo (N.M.), Shizuoka Cancer Center, Shizuoka (K.Y.), National Cancer Center Hospital, Tokyo (Y.S.), Hokkaido University Hospital, Hokkaido (Y.K.), and Taiho Pharmaceutical, Tokyo (M.I.) - all in Japan; Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, Seville (R.G.-C.), and Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (J.T.) - all in Spain; Centre Eugène Marquis, Rennes, France (E.B.); Royal Melbourne Hospital, Melbourne, VIC, Australia (B.T.); University of Southern California Norris Comprehensive Cancer Center, Los Angeles (H.-J.L.); Yale Cancer Center, New Haven, CT (H.H.); Taiho Oncology, Princeton, NJ (F.B., H.M.); and Stathmi, New Hope, PA (L.M.).

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http://dx.doi.org/10.1056/NEJMoa1414325DOI Listing
May 2015