Takayuki Morisaki

Takayuki Morisaki

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Takayuki Morisaki

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Histologic differences between the ascending and descending aortas in young adults with fibrillin-1 mutations.

J Thorac Cardiovasc Surg 2019 Feb 15. Epub 2019 Feb 15.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jtcvs.2019.01.126DOI Listing
February 2019

Role of AMPD2 in impaired glucose tolerance induced by high fructose diet.

Mol Genet Metab Rep 2017 Dec 24;13:23-29. Epub 2017 Jul 24.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/j.ymgmr.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527155PMC
December 2017

Clinical outcomes of aortic repair in young adult patients with ACTA2 mutations.

Gen Thorac Cardiovasc Surg 2017 Dec 14;65(12):686-691. Epub 2017 Aug 14.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.

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http://dx.doi.org/10.1007/s11748-017-0810-0DOI Listing
December 2017

Impact of connective tissue disease on the surgical outcomes of aortic dissection in patients with cystic medial necrosis.

J Cardiothorac Surg 2017 Nov 23;12(1):97. Epub 2017 Nov 23.

Cardiovascular Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku Shinjuku-ku Tokyo, 160, Tokyo, -0023, Japan.

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http://dx.doi.org/10.1186/s13019-017-0663-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701318PMC
November 2017

Cited4 is related to cardiogenic induction and maintenance of proliferation capacity of embryonic stem cell-derived cardiomyocytes during in vitro cardiogenesis.

PLoS One 2017 17;12(8):e0183225. Epub 2017 Aug 17.

Department of Genetic Medicine and Regenerative Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University, Yonago, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183225PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560578PMC
October 2017

Vestigial-like 2 contributes to normal muscle fiber type distribution in mice.

Sci Rep 2017 08 2;7(1):7168. Epub 2017 Aug 2.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka, 565-8565, Japan.

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http://dx.doi.org/10.1038/s41598-017-07149-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540913PMC
August 2017

Urat1-Uox double knockout mice are experimental animal models of renal hypouricemia and exercise-induced acute kidney injury.

Nucleosides Nucleotides Nucleic Acids 2016 Dec;35(10-12):543-549

d Department of Internal Medicine , Faculty of Medicine, Teikyo University , Tokyo , Japan.

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http://dx.doi.org/10.1080/15257770.2016.1143559DOI Listing
December 2016

Moyamoya disease and artery tortuosity as rare phenotypes in a patient with an elastin mutation.

Am J Med Genet A 2016 07 15;170(7):1924-7. Epub 2016 Apr 15.

Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://dx.doi.org/10.1002/ajmg.a.37662DOI Listing
July 2016

Genetic mutation analysis in Japanese patients with non-syndromic congenital heart disease.

J Hum Genet 2016 Feb 22;61(2):157-62. Epub 2015 Oct 22.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan.

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http://dx.doi.org/10.1038/jhg.2015.126DOI Listing
February 2016

Genetics of hereditary large vessel diseases.

J Hum Genet 2016 Jan 8;61(1):21-6. Epub 2015 Oct 8.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.

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http://dx.doi.org/10.1038/jhg.2015.119DOI Listing
January 2016

Erratum to: AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.

BMC Endocr Disord 2015 Dec 8;15:80. Epub 2015 Dec 8.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, 565-8565, Osaka, Japan.

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http://dx.doi.org/10.1186/s12902-015-0078-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673729PMC
December 2015

Reversible cerebral vasoconstriction syndrome and posterior reversible encephalopathy syndrome in a boy with Loeys-Dietz syndrome.

Am J Med Genet A 2015 Oct 22;167A(10):2435-9. Epub 2015 Jun 22.

Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1002/ajmg.a.37202DOI Listing
October 2015

Aortic Disease Presentation and Outcome Associated With ACTA2 Mutations.

Circ Cardiovasc Genet 2015 Jun 10;8(3):457-64. Epub 2015 Mar 10.

Departments of Internal Medicine (E.S.R., D.G., S.P., T.A.B., K.F., D.M.M.), Cardiothoracic and Vascular Surgery (A.E., H.S.), University of Texas Health Science Center at Houston; Department of Medicine, Stanford University Medical Center, CA (D.L.); Connective Tissue Gene Tests, Allentown, PA (J.H.); Department of Cardiac and Vascular Sciences, St. George's, University of London, London, United Kingdom (A.C., G.A.); AP-HP, Hôpital Bichat, Centre National de Référence pour le syndrome de Marfan et apparentés, Paris, France (C.B., G.J.), Université Paris 7, Paris, France (C.B., G.J.), AP-HP, Hôpital Bichat, Laboratoire de Génétique moléculaire, Boulogne, France (C.B.), and INSERM, U1148, Paris, France (C.B., G.J.); AP-HP, Hôpital Bichat, Service de Cardiologie, Paris, France (G.J.); Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO (A.B.); Genomic Medicine Institute, Cleveland Clinic, OH (R.M.); Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan (T.M., H.M.); Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.P.); Division of Cardiothoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX (J.C., S.L.); and Texas Heart Institute and Baylor St. Luke's Medical Center, Houston (J.C., S.L.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601641PMC
June 2015

AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.

BMC Endocr Disord 2015 Mar 27;15:11. Epub 2015 Mar 27.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka, 565-8565, Japan.

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http://bmcendocrdisord.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12902-015-0010-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520000PMC
March 2015

AMPD1: a novel therapeutic target for reversing insulin resistance.

BMC Endocr Disord 2014 Dec 15;14:96. Epub 2014 Dec 15.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1186/1472-6823-14-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274759PMC
December 2014

Acute rupture of chordae tendineae of the mitral valve in infants: a nationwide survey in Japan exploring a new syndrome.

Circulation 2014 Sep 25;130(13):1053-61. Epub 2014 Jul 25.

From the Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan (I.S., H.S., T.A., M.K., K. Kurosaki); the Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan (K.N.); the Department of Cardiology, National Center for Child Health and Development, Tokyo, Japan (H.K.); the Department of Pediatric Cardiology, Tokyo Women's Medical University, Tokyo, Japan (T.N.); the Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan (H.Y.); the Department of Cardiology, Fukuoka Children's Hospital, Fukuoka, Japan (K.S.); the Department of Clinical Pathology, National Cerebral and Cardiovascular Center, Osaka, Japan (Y.I.); the Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center, Osaka, Japan (T.M.); and the Department of Pediatric Cardiac Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan (T.H., K. Kagisaki, H.I.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.008592DOI Listing
September 2014

Acute dilatation of the ascending aorta and aortic valve regurgitation in Loeys-Dietz syndrome.

Ann Thorac Surg 2014 Jun;97(6):2188-90

Department of Cardiovascular Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1016/j.athoracsur.2013.08.021DOI Listing
June 2014

BMPR2 gene mutation in pulmonary arteriovenous malformation and pulmonary hypertension: a case report.

Respir Investig 2014 May 10;52(3):195-8. Epub 2013 Sep 10.

Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2013.08.003DOI Listing
May 2014

Hereditary hemorrhagic telangiectasia in Japanese patients.

J Hum Genet 2014 Jan 7;59(1):37-41. Epub 2013 Nov 7.

Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan.

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http://dx.doi.org/10.1038/jhg.2013.113DOI Listing
January 2014

Effect of isolated AMP deaminase deficiency on skeletal muscle function.

Mol Genet Metab Rep 2014 16;1:51-59. Epub 2014 Jan 16.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan; Department of Molecular Pathophysiology, Osaka University Graduate School of Pharmaceutical Sciences, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/j.ymgmr.2013.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121310PMC
January 2014

Co-existence of mutations in the FBN1 gene and the ABCC6 gene in a patient with Marfan syndrome associated with pseudoxanthoma elasticum.

J Dermatol Sci 2013 Dec 30;72(3):325-7. Epub 2013 Jul 30.

Department of Dermatology, Dokkyo Medical University, School of Medicine, Mibu, Tochigi, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2013.07.007DOI Listing
December 2013

Ependymal cells of the mouse brain express urate transporter 1 (URAT1).

Fluids Barriers CNS 2013 Oct 24;10(1):31. Epub 2013 Oct 24.

Department of Human Physiology and Pathology, Faculty of Pharma-Sciences, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.

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http://fluidsbarrierscns.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/2045-8118-10-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015888PMC
October 2013

Electrophysiological properties of prion-positive cardiac progenitors derived from murine embryonic stem cells.

Circ J 2012 4;76(12):2875-83. Epub 2012 Sep 4.

Division of Regenerative Medicine and Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Science, Yonago, Japan.

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http://dx.doi.org/10.1253/circj.cj-12-0126DOI Listing
May 2013

Artery tortuosity syndrome exhibiting early-onset emphysema with novel compound heterozygous SLC2A10 mutations.

Am J Med Genet A 2013 Apr 12;161A(4):856-9. Epub 2013 Mar 12.

Department of Pediatrics, Chiba University Graduate School of Medicine, Chiba, Japan.

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http://dx.doi.org/10.1002/ajmg.a.35776DOI Listing
April 2013

AMP deaminase 3 plays a critical role in remote reperfusion lung injury.

Biochem Biophys Res Commun 2013 Apr 29;434(1):131-6. Epub 2013 Mar 29.

Department of Genetic Medicine and Regenerative Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2013.03.056DOI Listing
April 2013

Surgical experience with aggressive aortic pathologic process in Loeys-Dietz syndrome.

Ann Thorac Surg 2012 Nov 24;94(5):1413-7. Epub 2012 Aug 24.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S000349751201326
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http://dx.doi.org/10.1016/j.athoracsur.2012.05.111DOI Listing
November 2012

AMPD3-deficient mice exhibit increased erythrocyte ATP levels but anemia not improved due to PK deficiency.

Genes Cells 2012 Nov 18;17(11):913-22. Epub 2012 Oct 18.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka, 565-8565, Japan.

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http://doi.wiley.com/10.1111/gtc.12006
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http://dx.doi.org/10.1111/gtc.12006DOI Listing
November 2012

CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population.

Hum Mutat 2012 Feb 8;33(2):402-10. Epub 2011 Dec 8.

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.

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http://dx.doi.org/10.1002/humu.21652DOI Listing
February 2012

Proteinuria in AMPD2-deficient mice.

Genes Cells 2012 Jan;17(1):28-38

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2011.01568.xDOI Listing
January 2012

Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction.

J Mol Biol 2011 Nov 12;413(4):857-78. Epub 2011 Sep 12.

Division of Regenerative Medicine and Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Science, Yonago, Japan.

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http://dx.doi.org/10.1016/j.jmb.2011.09.006DOI Listing
November 2011

[Genetic study of coronary artery disease].

Nihon Rinsho 2011 Sep;69 Suppl 7:246-50

Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute.

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September 2011

Association of four genetic loci with uric acid levels and reduced renal function: the J-SHIPP Suita study.

Am J Nephrol 2010 13;32(3):279-86. Epub 2010 Aug 13.

Department of Basic Medical Research and Education, Ehime University Graduate School of Medicine, Ehime, Japan. tabara @ m.ehime-u.ac.jp

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https://www.karger.com/Article/FullText/318943
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http://dx.doi.org/10.1159/000318943DOI Listing
December 2010

Differentiation of pharyngeal endoderm from mouse embryonic stem cell.

Stem Cells Dev 2010 Nov 13;19(11):1735-43. Epub 2010 Sep 13.

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1089/scd.2009.0466DOI Listing
November 2010

RNA-binding motif protein 24 regulates myogenin expression and promotes myogenic differentiation.

Genes Cells 2010 Nov;15(11):1158-67

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2010.01446.xDOI Listing
November 2010

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

Biomed Res 2010 Oct;31(5):301-5

Division of Molecular Medicine and Therapeutics, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan.

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http://dx.doi.org/10.2220/biomedres.31.301DOI Listing
October 2010

[Informed consent and ethical review].

Nihon Rinsho 2010 Aug;68 Suppl 8:317-21

Department of Bioscience, National Cardiovascular Center Research Institute.

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August 2010

High prevalence of vertebral artery tortuosity of Loeys-Dietz syndrome in comparison with Marfan syndrome.

Jpn J Radiol 2010 May 29;28(4):273-7. Epub 2010 May 29.

Department of Radiology and Nuclear Medicine, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, 565-8565, Japan.

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http://link.springer.com/10.1007/s11604-010-0420-6
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http://dx.doi.org/10.1007/s11604-010-0420-6DOI Listing
May 2010

The cellular prion protein identifies bipotential cardiomyogenic progenitors.

Circ Res 2010 Jan 12;106(1):111-9. Epub 2009 Nov 12.

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.209478DOI Listing
January 2010

RNA-binding proteins Rbm38 and Rbm24 regulate myogenic differentiation via p21-dependent and -independent regulatory pathways.

Genes Cells 2009 Nov 8;14(11):1241-52. Epub 2009 Oct 8.

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Osaka, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2009.01347.xDOI Listing
November 2009

T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation.

Proc Natl Acad Sci U S A 2009 Nov 21;106(44):18604-9. Epub 2009 Oct 21.

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0900635106
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http://dx.doi.org/10.1073/pnas.0900635106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773962PMC
November 2009

[Personal genetic information and ethical consideration: from medical viewpoint].

Nihon Rinsho 2009 Jun;67(6):1204-8

Department of Bioscience, National Cardiovascular Center Research Institute.

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June 2009

Resistin gene variations are associated with the metabolic syndrome in Japanese men.

Obes Res Clin Pract 2009 May;3(2):I-II

Department of Bioscience, National Cardiovascular Center Research Institute, Osaka, Japan.

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http://dx.doi.org/10.1016/j.orcp.2008.11.003DOI Listing
May 2009

Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy.

J Mol Biol 2008 Dec 7;384(4):896-907. Epub 2008 Oct 7.

Division of Regenerative Medicine and Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Science, Yonago, Japan.

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http://dx.doi.org/10.1016/j.jmb.2008.09.070DOI Listing
December 2008

Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells.

Biochem Biophys Res Commun 2008 Dec 18;377(2):413-418. Epub 2008 Oct 18.

Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2008.09.160DOI Listing
December 2008

Leptin gene and leptin receptor gene polymorphisms are associated with sweet preference and obesity.

Hypertens Res 2008 Jun;31(6):1069-77

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Japan.

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http://dx.doi.org/10.1291/hypres.31.1069DOI Listing
June 2008

[Urate production and regulation].

Nihon Rinsho 2008 Apr;66(4):653-8

Department of Bioscience, National Cardiovascular Center Research Institute.

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April 2008

[AMPD genes and urate metabolism].

Nihon Rinsho 2008 Apr;66(4):771-7

Department of Bioscience, National Cardiovascular Center Research Institute.

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April 2008

Activation of MEK-ERK by heregulin-beta1 promotes the development of cardiomyocytes derived from ES cells.

Biochem Biophys Res Commun 2007 Sep 23;361(3):732-8. Epub 2007 Jul 23.

Department of Biology and Institute of Life Science and Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Republic of Korea. [corrected]

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http://dx.doi.org/10.1016/j.bbrc.2007.07.045DOI Listing
September 2007

Endocardiogenesis in embryoid bodies: novel markers identified by gene expression profiling.

Biochem Biophys Res Commun 2007 Jun 17;357(4):896-902. Epub 2007 Apr 17.

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.04.030DOI Listing
June 2007

Efficient capture of cardiogenesis-associated genes expressed in ES cells.

Biochem Biophys Res Commun 2007 Mar 30;355(1):47-53. Epub 2007 Jan 30.

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.109DOI Listing
March 2007

Delayed onset of beating and decreased expression of T-type Ca2+ channel in mouse ES cell-derived cardiocytes carrying human chromosome 21.

Biochem Biophys Res Commun 2006 Dec 12;351(1):126-32. Epub 2006 Oct 12.

Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Tottori University Graduate School of Medical Science, 86 Nishi-cho, Yonago 683-8503, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.10.018DOI Listing
December 2006

Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis.

Proc Natl Acad Sci U S A 2006 Dec 14;103(52):19812-7. Epub 2006 Dec 14.

Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.

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http://dx.doi.org/10.1073/pnas.0605768103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1750922PMC
December 2006

[Metabolic syndrome and11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms].

Nihon Rinsho 2006 Dec;64 Suppl 9:334-8

Department of Atherosclerosis and Diabetes, National Cardiovascular Center.

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December 2006

[Challenges towards regenerative medicine].

Nihon Rinsho 2006 May;64(5):990-5

Department of Bioscience, National Cardiovascular Center Research Institute.

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May 2006

Impairment of cardiomyogenesis in embryonic stem cells lacking scaffold protein JSAP1.

Biochem Biophys Res Commun 2005 Dec 21;338(2):1152-7. Epub 2005 Oct 21.

Division of Cell Cycle Regulation, Cancer Research Institute, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-0934, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.10.052DOI Listing
December 2005

Subtype switching of T-type Ca 2+ channels from Cav3.2 to Cav3.1 during differentiation of embryonic stem cells to cardiac cell lineage.

Circ J 2005 Oct;69(10):1284-9

Division of Regenerative Medicine and Therapeutics, Department of Genetic Medicine and Regenerative Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University Graduate School of Medical Science, Japan.

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http://dx.doi.org/10.1253/circj.69.1284DOI Listing
October 2005

Partial correction of abnormal cardiac development in caspase-8-deficient mice by cardiomyocyte expression of p 35.

Transgenic Res 2005 Oct;14(5):593-604

Department of Animal Development and Physiology, Graduate School of Biostudies, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1007/s11248-005-4350-5DOI Listing
October 2005

Stable and uniform gene suppression by site-specific integration of siRNA expression cassette in murine embryonic stem cells.

Stem Cells 2005 Sep 7;23(8):1028-34. Epub 2005 Jun 7.

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1634/stemcells.2004-0335DOI Listing
September 2005

Recombinant HBsAg inhibits LPS-induced COX-2 expression and IL-18 production by interfering with the NFkappaB pathway in a human monocytic cell line, THP-1.

J Hepatol 2005 Sep;43(3):465-71

Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo 663, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S016882780500263
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http://dx.doi.org/10.1016/j.jhep.2005.02.033DOI Listing
September 2005

Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.

J Biol Chem 2005 May 13;280(20):19682-8. Epub 2005 Mar 13.

Division of Translational Research, Kyoto Medical Center, National Hospital Organization, Japan.

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http://dx.doi.org/10.1074/jbc.M412428200DOI Listing
May 2005

Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes.

Biochem Biophys Res Commun 2004 Dec;325(3):968-75

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.10.103DOI Listing
December 2004

Peroxisome proliferator-activated receptor gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2, and ciglitazone, induce growth inhibition and cell cycle arrest in hepatic oval cells.

Biochem Biophys Res Commun 2004 Sep;322(2):458-64

Division of Hepatobiliary and Pancreatic Disease, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawacho, Nishinomiya, Hyogo 663-8501, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0401626
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http://dx.doi.org/10.1016/j.bbrc.2004.07.133DOI Listing
September 2004

BMPR2 mutations found in Japanese patients with familial and sporadic primary pulmonary hypertension.

Hum Mutat 2004 Jun;23(6):632

Department of Bioscience, Osaka University Graduate School of Pharmaceutical Sciences, Suita, Osaka, Japan.

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http://dx.doi.org/10.1002/humu.9251DOI Listing
June 2004

The role of a common TNNT2 polymorphism in cardiac hypertrophy.

J Hum Genet 2004 24;49(3):129-133. Epub 2004 Feb 24.

Department of Cardiology, National Cardiovascular Center, Suita, Japan.

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http://dx.doi.org/10.1007/s10038-003-0121-4DOI Listing
May 2004

Single-nucleotide polymorphism g.1548G > A (E469K) in human ICAM-1 gene affects mRNA splicing pattern and TPA-induced apoptosis.

Biochem Biophys Res Commun 2004 May;317(3):729-35

Department of Bioscience, National Cardiovascular Center Research Institute, Suita, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.101DOI Listing
May 2004

[The application of denaturing high performance liquid chromatography in detection of novel polymorphisms in PAI-1gene].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2003 Oct;20(5):404-8

Emergency Department, Affiliated Beijing Tongren Hospital, Capital University of Medical Science, Beijing, 100730 PR China.

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October 2003

Expression of ErbB receptors in ES cell-derived cardiomyocytes.

Biochem Biophys Res Commun 2003 Sep;309(1):241-6

Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1, Fujishirodai, Suita, Osaka, Japan.

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http://dx.doi.org/10.1016/s0006-291x(03)01521-3DOI Listing
September 2003