Takayuki Hishiki

Takayuki Hishiki

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Takayuki Hishiki

Takayuki Hishiki

Publications by authors named "Takayuki Hishiki"

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Identification of inhibitors of dengue viral replication using replicon cells expressing secretory luciferase.

Antiviral Res 2019 12 31;172:104643. Epub 2019 Oct 31.

Laboratory of Primate Model, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan; Department of Microbiology, Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.104643DOI Listing
December 2019

Synthesis and biological evaluation of novel imidazole nucleosides as potential anti-dengue virus agents.

Bioorg Med Chem 2019 Jun 8;27(11):2181-2186. Epub 2019 Apr 8.

Graduate School of Pharmaceutical Science, Tokushima University, Shomachi 1-78-1, Tokushima 770-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.04.015DOI Listing
June 2019

An estrogen antagonist, cyclofenil, has anti-dengue-virus activity.

Arch Virol 2019 Jan 24;164(1):225-234. Epub 2018 Oct 24.

Department of Virology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku, Tokyo, 162-8640, Japan.

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http://link.springer.com/10.1007/s00705-018-4079-0
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http://dx.doi.org/10.1007/s00705-018-4079-0DOI Listing
January 2019

Correction to: An estrogen antagonist, cyclofenil, has anti-dengue-virus activity.

Arch Virol 2019 01;164(1):235

Department of Virology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku, Tokyo, 162-8640, Japan.

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http://dx.doi.org/10.1007/s00705-018-4107-0DOI Listing
January 2019

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251.

Biochem Biophys Rep 2018 Sep 1;15:1-6. Epub 2018 Jun 1.

Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.

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http://dx.doi.org/10.1016/j.bbrep.2018.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047365PMC
September 2018

Evaluation of Macaca radiata as a non-human primate model of Dengue virus infection.

Sci Rep 2018 02 21;8(1):3421. Epub 2018 Feb 21.

Laboratory of Primate Model, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41598-018-21582-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821881PMC
February 2018

Hirsutine, an Indole Alkaloid of , Inhibits Late Step in Dengue Virus Lifecycle.

Front Microbiol 2017 30;8:1674. Epub 2017 Aug 30.

Laboratory of Primate Model, Institute for Frontier Life and Medical Sciences, Kyoto UniversityKyoto, Japan.

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http://dx.doi.org/10.3389/fmicb.2017.01674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582420PMC
August 2017

Novel antiviral activity of bromocriptine against dengue virus replication.

Antiviral Res 2016 07 12;131:141-7. Epub 2016 May 12.

Laboratory of Primate Model, Institute for Virus Research, Kyoto University, Kyoto, Japan; Viral Infectious Diseases Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2016.04.014DOI Listing
July 2016

Generation of a neutralization-resistant CCR5 tropic simian/human immunodeficiency virus (SHIV-MK38) molecular clone, a derivative of SHIV-89.6.

J Gen Virol 2016 05 4;97(5):1249-1260. Epub 2016 Feb 4.

Laboratory of Primate Model, Experimental Research Center for Infectious Diseases, Institute for Virus Research,Kyoto University, 53 Shogoinkawaharacho, Sakyo-ku, Kyoto 606-8507,Japan.

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http://dx.doi.org/10.1099/jgv.0.000421DOI Listing
May 2016

Dengue Virus Reporter Replicon is a Valuable Tool for Antiviral Drug Discovery and Analysis of Virus Replication Mechanisms.

Viruses 2016 05 5;8(5). Epub 2016 May 5.

Viral Infectious Diseases Project, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.3390/v8050122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885077PMC
May 2016

Hepatitis C virus utilizes VLDLR as a novel entry pathway.

Proc Natl Acad Sci U S A 2016 Jan 23;113(1):188-93. Epub 2015 Dec 23.

Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba, 272-8516 Japan;

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http://dx.doi.org/10.1073/pnas.1506524113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711846PMC
January 2016

Apolipoprotein E, but Not Apolipoprotein B, Is Essential for Efficient Cell-to-Cell Transmission of Hepatitis C Virus.

J Virol 2015 Oct 22;89(19):9962-73. Epub 2015 Jul 22.

Molecular Biology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IP), Madrid, Spain CIBERehd, Instituto de Salud Carlos III, Madrid, Spain

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http://dx.doi.org/10.1128/JVI.00577-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577890PMC
October 2015

Development of a novel Dengue-1 virus replicon system expressing secretory Gaussia luciferase for analysis of viral replication and discovery of antiviral drugs.

Jpn J Infect Dis 2014 ;67(3):209-12

Laboratory of Primate Model, Experimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University.

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http://dx.doi.org/10.7883/yoken.67.209DOI Listing
March 2015

Interferon-mediated ISG15 conjugation restricts dengue virus 2 replication.

Biochem Biophys Res Commun 2014 May 21;448(1):95-100. Epub 2014 Apr 21.

Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive,Singapore 117599, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.04.081DOI Listing
May 2014

Generation of a replication-competent simian-human immunodeficiency virus, the neutralization sensitivity of which can be enhanced in the presence of a small-molecule CD4 mimic.

J Gen Virol 2013 Dec 11;94(Pt 12):2710-2716. Epub 2013 Sep 11.

Laboratory of Primate Model, Experimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1099/vir.0.055590-0DOI Listing
December 2013

Natural infection of cynomolgus monkeys with dengue virus occurs in epidemic cycles in the Philippines.

J Gen Virol 2013 Oct 12;94(Pt 10):2202-2207. Epub 2013 Jul 12.

Laboratory of Primate Model, Experimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1099/vir.0.055343-0DOI Listing
October 2013

The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.

Virus Res 2012 Jan 14;163(1):390-5. Epub 2011 Oct 14.

Department of Life and Environmental Sciences, Chiba Institute of Technology, 2-17-1 Tsudanuma, Narashino-shi, Chiba 275-0016, Japan.

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http://dx.doi.org/10.1016/j.virusres.2011.10.003DOI Listing
January 2012

Lipoprotein component associated with hepatitis C virus is essential for virus infectivity.

Curr Opin Virol 2011 Jul 12;1(1):19-26. Epub 2011 Jun 12.

Research Institute, Chiba Institute of Technology, Tsudanuma, Narashino, Chiba 275-0016, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S18796257110002
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http://dx.doi.org/10.1016/j.coviro.2011.05.017DOI Listing
July 2011

Hepatitis C virus utilizes lipid droplet for production of infectious virus.

Proc Jpn Acad Ser B Phys Biol Sci 2009 ;85(7):217-28

Research Institute, Chiba Institute of Technology, Chiba, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561845PMC
http://dx.doi.org/10.2183/pjab.85.217DOI Listing
October 2009

BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.

J Biol Chem 2007 Sep 20;282(39):28335-43. Epub 2007 Jul 20.

Department of Viral Oncology, Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1074/jbc.M702656200DOI Listing
September 2007

The lipid droplet is an important organelle for hepatitis C virus production.

Nat Cell Biol 2007 Sep 26;9(9):1089-97. Epub 2007 Aug 26.

Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1038/ncb1631DOI Listing
September 2007

Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125.

Proc Natl Acad Sci U S A 2007 May 25;104(18):7500-5. Epub 2007 Apr 25.

Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1073/pnas.0611551104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1863485PMC
May 2007

Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811.

Biochem Biophys Res Commun 2006 May 29;343(3):879-84. Epub 2006 Mar 29.

Laboratory of Human Tumor Viruses, Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.03.059DOI Listing
May 2006

Diverse effects of cyclosporine on hepatitis C virus strain replication.

J Virol 2006 May;80(9):4510-20

Laboratory of Human Tumor Viruses, Department of Viral Oncology, Institute for Virus Research, Kyoto University, 53 Kawaharacho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1128/JVI.80.9.4510-4520.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472040PMC
May 2006