Takayuki Hattori

Takayuki Hattori

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Takayuki Hattori

Publications by authors named "Takayuki Hattori"

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No increase in incidence of post-intravitreal injection endophthalmitis without topical antibiotics: a prospective study.

Jpn J Ophthalmol 2019 Sep 24;63(5):396-401. Epub 2019 Aug 24.

Department of Ophthalmology, School of Medicine, Nihon University Hospital, 1-6 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan.

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http://dx.doi.org/10.1007/s10384-019-00684-5DOI Listing
September 2019

Prospective study of vitrectomy for epiretinal membranes in patients with good best-corrected visual acuity.

BMC Ophthalmol 2019 Aug 14;19(1):183. Epub 2019 Aug 14.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Nihon University Hospital, 1-6 Kandasurugadai, Chiyoda-ku Tokyo, 101-8309, Japan.

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http://dx.doi.org/10.1186/s12886-019-1185-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693285PMC
August 2019

Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein.

Chem Pharm Bull (Tokyo) 2019 ;67(3):165-172

Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences.

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http://dx.doi.org/10.1248/cpb.c18-00703DOI Listing
April 2019

Intravitreal Injection of 1.25% Povidone Iodine Followed by Vitrectomy Using 0.025% Povidone Iodine Irrigation for Treating Endophthalmitis.

Transl Vis Sci Technol 2019 Jan 13;8(1):21. Epub 2019 Feb 13.

Department of Ophthalmology, Faculty of Medicine, Saitama Medical University, Iruma, Saitama, Japan.

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http://dx.doi.org/10.1167/tvst.8.1.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375116PMC
January 2019

Acquired Resistance to Shiga Toxin-Induced Apoptosis by Loss of CD77 Expression in Human Myelogenous Leukemia Cell Line, THP-1.

Biol Pharm Bull 2018 ;41(9):1475-1479

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences.

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https://www.jstage.jst.go.jp/article/bpb/41/9/41_b18-00277/_
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http://dx.doi.org/10.1248/bpb.b18-00277DOI Listing
November 2018

Design and synthesis of cell-permeable fluorescent nitrilotriacetic acid derivatives.

Bioorg Med Chem 2018 11 24;26(20):5494-5498. Epub 2018 Sep 24.

National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-9501, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183075
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http://dx.doi.org/10.1016/j.bmc.2018.09.028DOI Listing
November 2018

Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase.

Sci Rep 2018 09 10;8(1):13549. Epub 2018 Sep 10.

Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.

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http://dx.doi.org/10.1038/s41598-018-31913-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131351PMC
September 2018

Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins.

J Med Chem 2018 01 10;61(2):576-582. Epub 2017 May 10.

Division of Organic Chemistry, National Institute of Health Sciences , 1-18-1, Kamiyoga, Setagaya, Tokyo 158-8501, Japan.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00413DOI Listing
January 2018

Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands.

J Med Chem 2018 01 23;61(2):543-575. Epub 2017 Jun 23.

Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences , 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00168DOI Listing
January 2018

Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation.

ACS Med Chem Lett 2017 Oct 14;8(10):1042-1047. Epub 2017 Sep 14.

Divisions of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo, Japan.

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http://dx.doi.org/10.1021/acsmedchemlett.7b00247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641955PMC
October 2017

Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide.

Bioorg Med Chem Lett 2017 09 2;27(18):4478-4481. Epub 2017 Aug 2.

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, 1-18-1, Kamiyoga, Setagaya, Tokyo 158-8501, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X173078
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http://dx.doi.org/10.1016/j.bmcl.2017.08.001DOI Listing
September 2017

Reduced anterior chamber contamination by frequent surface irrigation with diluted iodine solutions during cataract surgery.

Acta Ophthalmol 2017 Aug 8;95(5):e373-e378. Epub 2017 Mar 8.

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.

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http://dx.doi.org/10.1111/aos.13390DOI Listing
August 2017

Wet laboratory training using porcine eyes with eyelids.

Can J Ophthalmol 2017 Aug 15;52(4):398-402. Epub 2017 Mar 15.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jcjo.2017.01.007DOI Listing
August 2017

Modifying the planning target volume to optimize the dose distribution in dynamic conformal arc therapy for large metastatic brain tumors.

Jpn J Radiol 2017 Jun 6;35(6):335-340. Epub 2017 Apr 6.

Department of Radiation Oncology, Kobe City Medical Center General Hospital, 2-1-1 Minatojima-Minamimachi Chuo-ku, Kobe, 6500047, Japan.

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http://dx.doi.org/10.1007/s11604-017-0639-6DOI Listing
June 2017

SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib.

Cancer Sci 2017 May 26;108(5):1032-1041. Epub 2017 Apr 26.

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Setagaya-ku, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.13198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448626PMC
May 2017

Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.

Mol Pharmacol 2017 03 13;91(3):159-166. Epub 2016 Dec 13.

Division of Molecular Target and Gene Therapy Products (K.O., N.O., T.H., N.S., M.N.), and Division of Organic Chemistry (T.S., Y.D., M.K.), National Institutes of Health Sciences, Tokyo; Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima (K.O., R.O., R.S., A.I., H.K., H.S.); Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo (Y.I., M.I., Y.H.); Showa Pharmaceutical University, Machida (S.I.), Japan

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http://molpharm.aspetjournals.org/lookup/doi/10.1124/mol.116
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http://dx.doi.org/10.1124/mol.116.105569DOI Listing
March 2017

Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy.

Curr Cancer Drug Targets 2016 ;16(2):136-46

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

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http://dx.doi.org/10.2174/1568009616666151112122502DOI Listing
October 2016

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand.

Bioorg Med Chem Lett 2016 10 15;26(20):4865-4869. Epub 2016 Sep 15.

Division of Organic Chemistry, National Institute of Health Sciences, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.09.041DOI Listing
October 2016

Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα.

Methods Mol Biol 2016 ;1366:549-560

Division of Biochemistry and Molecular Biology, National Institute of Health Sciences, Kamiyoga, Setagaya-ku, Tokyo, 158-8501, Japan.

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http://dx.doi.org/10.1007/978-1-4939-3127-9_42DOI Listing
August 2016

M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin.

Genes Cells 2016 Aug 15;21(8):901-6. Epub 2016 Jun 15.

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo, 158-8501, Japan.

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http://dx.doi.org/10.1111/gtc.12386DOI Listing
August 2016

A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery Tool.

Chembiochem 2016 Jan 3;17(2):137-40. Epub 2015 Dec 3.

National Institute of Health Sciences, Setagaya, Tokyo, 158-8501, Japan.

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http://dx.doi.org/10.1002/cbic.201500468DOI Listing
January 2016

Piezo-actuated parallel mechanism for biological cell release at high speed.

Biomed Microdevices 2015 Oct;17(5):98

The Hamlyn Centre for Robotic Surgery, Imperial College London, London, SW7 2AZ, UK,

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http://dx.doi.org/10.1007/s10544-015-0001-7DOI Listing
October 2015

RANDOMIZED CONTROLLED STUDY OF INTRAVITREAL BEVACIZUMAB 0.16 MG INJECTED ONE DAY BEFORE SURGERY FOR PROLIFERATIVE DIABETIC RETINOPATHY.

Retina 2015 Sep;35(9):1800-7

Department of Ophthalmology, School of Medicine, Nihon University, Chiyodaku, Japan.

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http://dx.doi.org/10.1097/IAE.0000000000000577DOI Listing
September 2015

Proteasome inhibitors prevent cell death and prolong survival of mice challenged by Shiga toxin.

FEBS Open Bio 2015 12;5:605-14. Epub 2015 Jun 12.

Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Tokyo 158-8501, Japan.

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http://dx.doi.org/10.1016/j.fob.2015.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534485PMC
August 2015

Vitrectomy using 0.025% povidone-iodine in balanced salt solution plus for the treatment of postoperative endophthalmitis.

Retina 2015 Jun;35(6):1087-94

*Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan; and †Sagami Research Laboratories, Kanagawa, Japan.

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http://dx.doi.org/10.1097/IAE.0000000000000634DOI Listing
June 2015

Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells.

PLoS One 2014 21;9(1):e86709. Epub 2014 Jan 21.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore ; Department of Biochemistry, National University of Singapore, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086709PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897739PMC
September 2014

High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1β secretion.

Biochem Biophys Res Commun 2014 Sep 30;452(3):593-9. Epub 2014 Aug 30.

Division of Biochemistry and Metabolism, Division of Biochemistry and Molecular Biology, Division of Environmental Chemistry, Division of Risk Assessment, and Biological Safety Research Center, National Institute of Health Sciences, Tokyo 158-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.08.118DOI Listing
September 2014

Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery.

Int Ophthalmol 2014 Apr 27;34(2):211-6. Epub 2013 Jun 27.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan,

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http://dx.doi.org/10.1007/s10792-013-9816-5DOI Listing
April 2014

Interaction between RB protein and NuMA is required for proper alignment of spindle microtubules.

Genes Cells 2014 Feb 19;19(2):89-96. Epub 2013 Dec 19.

Research Equipment Center, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan; Cancer Science Institute of Singapore (CSI-Singapore), National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, #12-01, 117599, Singapore.

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http://dx.doi.org/10.1111/gtc.12119DOI Listing
February 2014

Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.

Cancer Sci 2013 Nov 11;104(11):1492-8. Epub 2013 Oct 11.

Division of Biochemistry and Molecular Biology, National Institute of Health Sciences, Tokyo, Japan.

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http://dx.doi.org/10.1111/cas.12272DOI Listing
November 2013

Minimizing the endophthalmitis rate following intravitreal injections using 0.25% povidone-iodine irrigation and surgical mask.

Graefes Arch Clin Exp Ophthalmol 2013 Aug 7;251(8):1885-90. Epub 2013 Feb 7.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo 101-8309, Japan.

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http://dx.doi.org/10.1007/s00417-013-2274-yDOI Listing
August 2013

Reducing bacterial contamination inside fluid catch bag in 25-gauge vitrectomy by use of 0.25 % povidone-iodine ocular surface irrigation.

Int Ophthalmol 2013 Feb 11;33(1):35-8. Epub 2012 Sep 11.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10792-012-9621-6DOI Listing
February 2013

Reduction of vitreous contamination rate after 25-gauge vitrectomy by surface irrigation with 0.25% povidone-iodine.

Retina 2013 Jan;33(1):143-51

Department of Ophthalmology, School of Medicine, Nihon University, Chiyodaku, Tokyo, Japan.

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http://dx.doi.org/10.1097/IAE.0b013e318261a6ceDOI Listing
January 2013

Clear visualization of anterior vitreous incarceration into cannulae during 25-gauge vitrectomy in eyes with asteroid hyalosis.

Eur J Ophthalmol 2012 Mar-Apr;22(2):293-5

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.

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http://dx.doi.org/10.5301/ejo.5000022DOI Listing
August 2012

Depiction of the vitreous pocket by optical coherence tomography.

Int Ophthalmol 2011 Feb 21;31(1):51-3. Epub 2010 Sep 21.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan.

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http://dx.doi.org/10.1007/s10792-010-9398-4DOI Listing
February 2011

A new infusion sustainer that stabilizes perfusion during sutureless 25-gauge vitrectomy.

Int Ophthalmol 2010 Dec 2;30(6):735-8. Epub 2010 Apr 2.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, 101-8309, Japan.

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http://link.springer.com/10.1007/s10792-010-9365-0
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http://dx.doi.org/10.1007/s10792-010-9365-0DOI Listing
December 2010

Highly viscous fluid in macular holes.

Int Ophthalmol 2010 Jun 28;30(3):319-21. Epub 2009 Aug 28.

Department of Ophthalmology, School of Medicine, Nihon University, 1-8-13 Surugadai Kanda, Chiyodaku, Tokyo, 101-8309, Japan.

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http://dx.doi.org/10.1007/s10792-009-9321-zDOI Listing
June 2010

Statin-induced Ca(2+) release was increased in B lymphocytes in patients who showed elevated serum creatine kinase during statin treatment.

J Atheroscler Thromb 2009 22;16(6):870-7. Epub 2009 Dec 22.

Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.5551/jat.2048DOI Listing
April 2010

Three-dimensional depiction of the vitreous pocket using triamcinolone acetonide.

Eur J Ophthalmol 2009 Nov-Dec;19(6):1102-5

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo - Japan.

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January 2010

New diagnostic criteria of acute pancreatitis.

J Hepatobiliary Pancreat Sci 2010 Jan 11;17(1):24-36. Epub 2009 Dec 11.

Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Minaminokawa, Ogaki, Gifu, 503-0864, Japan.

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http://dx.doi.org/10.1007/s00534-009-0214-3DOI Listing
January 2010

Therapeutic intervention and surgery of acute pancreatitis.

J Hepatobiliary Pancreat Sci 2010 Jan 12;17(1):53-9. Epub 2009 Dec 12.

Department of Surgery, Teikyo University School of Medicine, 2-11-1, Kaga-cho, Itabashi, Tokyo, 173-8605, Japan.

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http://dx.doi.org/10.1007/s00534-009-0211-6DOI Listing
January 2010

Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.

J Biol Chem 2009 Oct 13;284(41):27766-79. Epub 2009 Aug 13.

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1074/jbc.M109.006809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788827PMC
October 2009

Bimanual anterior vitrectomy using a 25-gauge high-speed cutter to manage vitreous loss during phacoemulsification.

Int Ophthalmol 2009 Aug 13;29(4):253-5. Epub 2008 Mar 13.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, Japan.

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http://link.springer.com/10.1007/s10792-008-9210-x
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http://dx.doi.org/10.1007/s10792-008-9210-xDOI Listing
August 2009

Double staining with brilliant blue G and double peeling for epiretinal membranes.

Ophthalmology 2009 Jul 8;116(7):1370-6. Epub 2009 May 8.

Department of Ophthalmology, School of Medicine, Nihon University, Surugadai, Kanda, Chiyodaku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2009.01.024DOI Listing
July 2009

Transient increase in macular edema following vitrectomy for retinal branch vein occlusion.

Int Ophthalmol 2009 Apr 16;29(2):95-8. Epub 2007 Nov 16.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo, Japan.

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http://link.springer.com/10.1007/s10792-007-9173-3
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http://dx.doi.org/10.1007/s10792-007-9173-3DOI Listing
April 2009

Pathological findings of multifocal choroiditis with panuveitis and punctate inner choroidopathy.

Jpn J Ophthalmol 2008 Jul-Aug;52(4):282-288. Epub 2008 Sep 5.

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10384-008-0566-2DOI Listing
January 2009

Early onset of rhegmatogenous retinal detachment after LASIK with femtosecond laser.

Jpn J Ophthalmol 2009 Jan 30;53(1):75-76. Epub 2009 Jan 30.

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.

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http://link.springer.com/10.1007/s10384-008-0612-0
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http://dx.doi.org/10.1007/s10384-008-0612-0DOI Listing
January 2009

Incidence of endophthalmitis after 20- and 25-gauge vitrectomy causes and prevention.

Ophthalmology 2008 Dec 18;115(12):2215-20. Epub 2008 Oct 18.

Department of Ophthalmology, School of Medicine, Nihon University, Kanda, Chiyodaku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ophtha.2008.07.015DOI Listing
December 2008

Frequency, source, and prevention of cotton fibers in the anterior chamber during cataract surgery.

J Cataract Refract Surg 2008 Aug;34(8):1389-92

Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jcrs.2008.04.021DOI Listing
August 2008

Suppressive effects of magnesium oxide materials on cadmium uptake and accumulation into rice grains II: Suppression of cadmium uptake and accumulation into rice grains due to application of magnesium oxide materials.

J Hazard Mater 2008 Jun 13;154(1-3):294-9. Epub 2007 Oct 13.

Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, Japan.

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http://dx.doi.org/10.1016/j.jhazmat.2007.10.025DOI Listing
June 2008

Suppressive effects of magnesium oxide materials on cadmium uptake and accumulation into rice grains I: Characteristics of magnesium oxide materials for cadmium sorption.

J Hazard Mater 2008 Jun 17;154(1-3):287-93. Epub 2007 Nov 17.

Graduate School of Bio-Applications and Systems Engineering, Tokyo University of Agriculture and Technology, 2-24-16, Naka-cho, Koganei, Tokyo 184-8588, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S030438940701589
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http://dx.doi.org/10.1016/j.jhazmat.2007.10.119DOI Listing
June 2008

Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit.

Biomed Res 2008 Feb;29(1):53-60

Department of Biochemistry 1, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

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http://dx.doi.org/10.2220/biomedres.29.53DOI Listing
February 2008

Contribution of extracellular signal-regulated kinases to the IL-1-induced growth inhibition of human melanoma cells A375.

Int Immunopharmacol 2008 Jan 9;8(1):80-9. Epub 2007 Nov 9.

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho 3-1, Nagoya 467-8603, Japan.

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http://dx.doi.org/10.1016/j.intimp.2007.10.013DOI Listing
January 2008

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion.

J Biol Chem 2007 Dec 14;282(49):35687-94. Epub 2007 Sep 14.

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.

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http://dx.doi.org/10.1074/jbc.M703735200DOI Listing
December 2007

Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1.

Cancer Res 2007 Nov;67(22):10789-95

Department of Biochemistry 1, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu, Japan.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-07-2033DOI Listing
November 2007

ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells.

Carcinogenesis 2007 Aug 17;28(8):1752-8. Epub 2007 May 17.

Second Department of Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1093/carcin/bgm120DOI Listing
August 2007

Thermal injury caused by chandelier fiber probe.

Am J Ophthalmol 2007 Jan 1;143(1):167-9. Epub 2006 Sep 1.

Department of Ophthalmology, School of Medicine, Surugadai Hospital of Nihon University, 1-8-13 Surugadai, Kanda, Chiyodaku, Tokyo 101-8309, Japan.

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http://dx.doi.org/10.1016/j.ajo.2006.07.049DOI Listing
January 2007

25-gauge scleral tunnel transconjunctival vitrectomy.

Am J Ophthalmol 2006 Nov;142(5):871-3

Department of Ophthalmology, School of Medicine, Nihon University, Kanda, Chiyodaku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ajo.2006.05.057DOI Listing
November 2006

Effects of MdmX on Mdm2-mediated downregulation of pRB.

FEBS Lett 2006 Mar 21;580(7):1753-8. Epub 2006 Feb 21.

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1016/j.febslet.2006.02.029DOI Listing
March 2006

Generation of a constitutively active mutant of human GPR48/LGR4, a G-protein-coupled receptor.

Hokkaido Igaku Zasshi 2006 Mar;81(2):101-5, 107, 109

Departments of Biochemistry 1, Hamamatsu University School of Medicine, Hamamatsu, 431-3192, Japan.

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March 2006

Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner.

Biochem Biophys Res Commun 2006 Feb 6;340(1):54-61. Epub 2005 Dec 6.

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.11.148DOI Listing
February 2006

Ubiquitin-dependent degradation of adenovirus E1A protein is inhibited by BS69.

Biochem Biophys Res Commun 2006 Jan 14;339(1):367-74. Epub 2005 Nov 14.

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.11.028DOI Listing
January 2006

Transcriptional induction of Smurf2 ubiquitin ligase by TGF-beta.

FEBS Lett 2005 May 7;579(12):2557-63. Epub 2005 Apr 7.

First Department of Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan.

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http://dx.doi.org/10.1016/j.febslet.2005.03.069DOI Listing
May 2005

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death.

EMBO J 2005 Mar 10;24(6):1243-55. Epub 2005 Mar 10.

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho, Nagoya, Japan.

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http://dx.doi.org/10.1038/sj.emboj.7600596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC556400PMC
March 2005

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.

Proc Natl Acad Sci U S A 2004 Jun 1;101(23):8687-92. Epub 2004 Jun 1.

First Department of Medicine and Department of Biochemistry 1, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1073/pnas.0400035101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423256PMC
June 2004

Cks1 is degraded via the ubiquitin-proteasome pathway in a cell cycle-dependent manner.

Genes Cells 2003 Nov;8(11):889-96

Department of Biochemistry 1, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1046/j.1365-2443.2003.00684.xDOI Listing
November 2003

High expression of Cks1 in human non-small cell lung carcinomas.

Biochem Biophys Res Commun 2003 Apr;303(3):978-84

Second Department of Internal Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Hamamatsu, Shizuoka 431-3192, Japan.

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http://dx.doi.org/10.1016/s0006-291x(03)00469-8DOI Listing
April 2003

C/EBP homologous protein (CHOP) up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.

FEBS Lett 2003 Apr;541(1-3):33-9

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho, Japan.

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http://dx.doi.org/10.1016/s0014-5793(03)00283-7DOI Listing
April 2003

C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.

Oncogene 2003 Mar;22(9):1273-80

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Mizuho, Japan.

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http://dx.doi.org/10.1038/sj.onc.1206204DOI Listing
March 2003

[A report of two cases of priapism with metastatic penile tumor].

Nihon Hinyokika Gakkai Zasshi 2002 May;93(4):568-72

Department of Urology, Chubu-Rosai Hospital, Nagoya, Japan.

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http://dx.doi.org/10.5980/jpnjurol1989.93.568DOI Listing
May 2002