Publications

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy.
Nat Commun 2017 May 22;8:15338. Epub 2017 May 22.
Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

Suppression of Th2 and Tfh immune reactions by Nr4a receptors in mature T reg cells.
J Exp Med 2015 Sep 24;212(10):1623-40. Epub 2015 Aug 24.
Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan Japan Science and Technology Agency (JST), Core Research for Evolutional Science and Technology, Chiyoda-ku, Tokyo 102-0075, Japan

Bruton's tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury.
Nat Commun 2015 Jun 10;6:7360. Epub 2015 Jun 10.
1] Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan [2] Japan Science and Technology Agency (JST), CREST, Chiyoda-ku, Tokyo 102-0075, Japan.

ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells.
Proc Natl Acad Sci U S A 2015 Jan 24;112(1):160-5. Epub 2014 Dec 24.
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo 160-8582, Japan; Core Research for Evolutional Science and Technology Program, Japan Science and Technology Agency, Tokyo 102-0076, Japan;


Smad2/3 and IRF4 play a cooperative role in IL-9-producing T cell induction.
J Immunol 2013 Sep 2;191(5):2360-71. Epub 2013 Aug 2.
Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.




Forced expression of stabilized c-Fos in dendritic cells reduces cytokine production and immune responses in vivo.
Biochem Biophys Res Commun 2012 Jun 24;423(2):247-52. Epub 2012 May 24.
Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo 160-8582, Japan.

Low dose CP-690,550 (tofacitinib), a pan-JAK inhibitor, accelerates the onset of experimental autoimmune encephalomyelitis by potentiating Th17 differentiation.
Biochem Biophys Res Commun 2012 Feb 9;418(2):234-40. Epub 2012 Jan 9.
Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin.
Immunity 2011 May 19;34(5):741-54. Epub 2011 May 19.
Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.

Suppression of SOCS3 expression in the pancreatic beta-cell leads to resistance to type 1 diabetes.
Biochem Biophys Res Commun 2007 Aug 4;359(4):952-8. Epub 2007 Jun 4.
Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.


Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia.
Circulation 2005 Feb 14;111(7):913-9. Epub 2005 Feb 14.
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan.

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