Publications by authors named "Takashi Kohno"

100Publications

Long-read sequencing for non-small-cell lung cancer genomes.

Genome Res 2020 Sep 4;30(9):1243-1257. Epub 2020 Sep 4.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8562, Japan.

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http://dx.doi.org/10.1101/gr.261941.120DOI Listing
September 2020

Effect of long-term amiodarone treatment on thyroid function in euthyroid Japanese patients: a 12-month retrospective analysis.

Endocr J 2020 Aug 18. Epub 2020 Aug 18.

Division of Endocrinology, Metabolism, and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ20-0307DOI Listing
August 2020

Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium.

Cancer Epidemiol Biomarkers Prev 2020 Jul 22. Epub 2020 Jul 22.

Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0248DOI Listing
July 2020

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.

Nat Genet 2020 07 8;52(7):669-679. Epub 2020 Jun 8.

Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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http://dx.doi.org/10.1038/s41588-020-0640-3DOI Listing
July 2020

Successful Surgical Treatment Combined With Infliximab in a Patient With Acute Aortic Regurgitation Caused by Behçet Disease.

Can J Cardiol 2020 Jul 29;36(7):1161.e3-1161.e5. Epub 2020 Mar 29.

Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.cjca.2020.03.029DOI Listing
July 2020

Simple prediction model for homologous recombination deficiency in breast cancers in adolescents and young adults.

Breast Cancer Res Treat 2020 Jul 3;182(2):491-502. Epub 2020 Jun 3.

Division of Genome Biology, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1007/s10549-020-05716-0DOI Listing
July 2020

Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy.

Hum Pathol 2020 Jul 7;101:80-81. Epub 2020 May 7.

Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima, 960-1295, Japan.

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http://dx.doi.org/10.1016/j.humpath.2020.04.009DOI Listing
July 2020

Exercise intolerance in chronic thromboembolic pulmonary hypertension after pulmonary angioplasty.

Eur Respir J 2020 Jul 9;56(1). Epub 2020 Jul 9.

Dept of Cardiovascular Medicine, Kyorin University Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1183/13993003.01982-2019DOI Listing
July 2020

BRAF V600E mutation is a potential therapeutic target for a small subset of synovial sarcoma.

Mod Pathol 2020 09 1;33(9):1660-1668. Epub 2020 Apr 1.

Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41379-020-0530-3DOI Listing
September 2020

Clonal Hematopoiesis From Next Generation Sequencing of Plasma From a Patient With Lung Adenocarcinoma: A Case Report.

Front Oncol 2020 13;10:113. Epub 2020 Feb 13.

Division of Translational Genomics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Tokyo, Japan.

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http://dx.doi.org/10.3389/fonc.2020.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031249PMC
February 2020

Precision medicine for ovarian clear cell carcinoma based on gene alterations.

Int J Clin Oncol 2020 Mar 4;25(3):419-424. Epub 2020 Feb 4.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10147-020-01622-zDOI Listing
March 2020

Optimal sampling in derivation studies was associated with improved discrimination in external validation for heart failure prognostic models.

J Clin Epidemiol 2020 May 29;121:71-80. Epub 2020 Jan 29.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan; Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Hokkaido, Japan.

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http://dx.doi.org/10.1016/j.jclinepi.2020.01.011DOI Listing
May 2020

Characterization of cancer omics and drug perturbations in panels of lung cancer cells.

Sci Rep 2019 12 20;9(1):19529. Epub 2019 Dec 20.

Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.

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http://dx.doi.org/10.1038/s41598-019-55692-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925249PMC
December 2019

Efficacy of glutathione inhibitors for the treatment of ARID1A-deficient diffuse-type gastric cancers.

Biochem Biophys Res Commun 2020 02 22;522(2):342-347. Epub 2019 Nov 22.

Division of Cancer Therapeutics, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.11.078DOI Listing
February 2020

REToma: a cancer subtype with a shared driver oncogene.

Carcinogenesis 2020 04;41(2):123-129

Division of Genome Biology, National Cancer Center Research Institute, Tsukiji, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1093/carcin/bgz184DOI Listing
April 2020

Therapeutic preferability of gemcitabine for ARID1A-deficient ovarian clear cell carcinoma.

Gynecol Oncol 2019 12 8;155(3):489-498. Epub 2019 Oct 8.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Molecular Oncology, The Jikei University Graduate School of Medicine, Tokyo, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258193155
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http://dx.doi.org/10.1016/j.ygyno.2019.10.002DOI Listing
December 2019

Subependymal giant cell astrocytoma harboring a PRRC2B-ALK fusion: A case report.

Pediatr Blood Cancer 2019 12 10;66(12):e27995. Epub 2019 Sep 10.

Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1002/pbc.27995DOI Listing
December 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2020 03 12;112(2):1223-1232. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954985PMC
March 2020

Balloon pulmonary angioplasty attenuates sleep apnea in patients with chronic thromboembolic pulmonary hypertension.

Heart Lung 2019 Jul - Aug;48(4):321-324. Epub 2019 Apr 24.

Division of Cardiology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.hrtlng.2019.04.001DOI Listing
March 2020

Next-Generation Sequencer Analysis of Pulmonary Pleomorphic Carcinoma With a CD74-ROS1 Fusion Successfully Treated With Crizotinib.

J Thorac Oncol 2019 05;14(5):e106-e108

Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan; Cancer Medicine, Jikei University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jtho.2019.01.005DOI Listing
May 2019

High-grade glioneuronal tumor with an ARHGEF2-NTRK1 fusion gene.

Brain Tumor Pathol 2019 Jul 22;36(3):121-128. Epub 2019 Apr 22.

Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.

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http://dx.doi.org/10.1007/s10014-019-00345-yDOI Listing
July 2019

Discrepancy between patient-reported quality of life and the prognostic assessment of Japanese patients hospitalized with acute heart failure.

Heart Vessels 2019 Sep 18;34(9):1464-1470. Epub 2019 Mar 18.

Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1007/s00380-019-01378-1DOI Listing
September 2019

Endometrial cancer arising after complete remission of uterine malignant lymphoma: A case report and mutation analysis.

Gynecol Oncol Rep 2019 May 27;28:50-53. Epub 2019 Feb 27.

Department of Gynecology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1016/j.gore.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402229PMC
May 2019

Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers.

Cancer Cell 2019 02 24;35(2):177-190.e8. Epub 2019 Jan 24.

Division of Genome Biology, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo 104-0045, Japan; Molecular Oncology, The Jikei University Graduate School of Medicine, 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.12.009DOI Listing
February 2019

Excessive Daytime Sleepiness, Depression and Sleep-Disordered Breathing in Patients With Cardiovascular Disease - Reply.

Circ J 2019 02 23;83(3):693. Epub 2019 Jan 23.

Division of Cardiology, Department of Medicine, Keio University School of Medicine.

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http://dx.doi.org/10.1253/circj.CJ-18-1198DOI Listing
February 2019

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors.

Acta Neuropathol Commun 2018 12 4;6(1):134. Epub 2018 Dec 4.

Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-018-0630-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278135PMC
December 2018

Evaluation and application of RNA-Seq by MinION.

DNA Res 2019 Feb;26(1):55-65

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/dnares/dsy038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379022PMC
February 2019

Radiopathologic correlation of collision lung cancer with ground-glass opacity.

Asian Cardiovasc Thorac Ann 2019 Jan 11;27(1):45-48. Epub 2018 Nov 11.

2 Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1177/0218492318811549DOI Listing
January 2019

Identification of a novel therapeutic target in driver-negative non-small cell lung cancer.

Transl Lung Cancer Res 2018 Sep;7(Suppl 3):S218-S220

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://dx.doi.org/10.21037/tlcr.2018.08.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193893PMC
September 2018

Identification of a novel KLC1-ROS1 fusion in a case of pediatric low-grade localized glioma.

Brain Tumor Pathol 2019 Jan 22;36(1):14-19. Epub 2018 Oct 22.

Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://link.springer.com/10.1007/s10014-018-0330-3
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http://dx.doi.org/10.1007/s10014-018-0330-3DOI Listing
January 2019

Copper transporter ATP7A interacts with IQGAP1, a Rac1 binding scaffolding protein: role in PDGF-induced VSMC migration and vascular remodeling.

Am J Physiol Cell Physiol 2018 12 26;315(6):C850-C862. Epub 2018 Sep 26.

Departments of Medicine (Section of Cardiology) and Pharmacology, Center for Cardiovascular Research, University of Illinois at Chicago , Chicago, Illinois.

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http://dx.doi.org/10.1152/ajpcell.00230.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336942PMC
December 2018

Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.

Cancer Treat Res Commun 2018 1;15:21-31. Epub 2018 Mar 1.

Genomes For life-GCAT Lab. Program of Predictive and Personalized Medicine of Cancer (PMPPC), Institute for Health Science Research Germans Trias i Pujol (IGTP), Can Ruti Biomedical Campus, Crta de Can Ruti, Camí de les Escoles S/N, 08916 Badalona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ctarc.2018.02.003DOI Listing
June 2019

The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer.

Lung Cancer 2018 09 19;123:127-135. Epub 2018 Jul 19.

Department of Cellular and Organ Pathology, Graduate School of Medicine, Akita University, 1-1-1 Hondo, Akita City, Akita, 010-8543, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.07.015DOI Listing
September 2018

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

EBioMedicine 2018 Jul 7;33:33-48. Epub 2018 Jul 7.

Laboratory of Molecular Carcinogenesis, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085539PMC
July 2018

Sleep-disordered breathing in the elderly: is it distinct from that in the younger or middle-aged populations?

J Thorac Dis 2018 Apr;10(Suppl 9):S1102-S1107

Division of Cardiology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.21037/jtd.2018.03.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949438PMC
April 2018

Outcome of hospitalised heart failure in Japan and the United Kingdom stratified by plasma N-terminal pro-B-type natriuretic peptide.

Clin Res Cardiol 2018 Dec 21;107(12):1103-1110. Epub 2018 May 21.

Department of Cardiology, Hull York Medical School, Hull and East Yorkshire Medical Research and Teaching Centre, Castle Hill Hospital, Cottingham, Kingston upon Hull, UK.

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http://dx.doi.org/10.1007/s00392-018-1283-6DOI Listing
December 2018

Development of targeted therapy and immunotherapy for treatment of small cell lung cancer.

Jpn J Clin Oncol 2018 Jul;48(7):603-608

Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine.

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http://dx.doi.org/10.1093/jjco/hyy068DOI Listing
July 2018

The first case of SMARCB1 (INI1) - deficient squamous cell carcinoma of the pleura: a case report.

BMC Cancer 2018 04 7;18(1):398. Epub 2018 Apr 7.

Department of Thoracic Oncology, National Cancer Center Hospital, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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http://dx.doi.org/10.1186/s12885-018-4321-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889546PMC
April 2018

Early versus late readmission during the vulnerable phase following hospitalization for heart failure.

Eur J Heart Fail 2018 07 30;20(7):1165-1166. Epub 2018 Mar 30.

Division of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.

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http://dx.doi.org/10.1002/ejhf.1179DOI Listing
July 2018

Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines.

Sci Rep 2018 03 21;8(1):4926. Epub 2018 Mar 21.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan.

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http://dx.doi.org/10.1038/s41598-018-23342-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862974PMC
March 2018

Primary adenocarcinoma of the trachea revealing a mucinous bronchial gland cell origin.

Pathol Res Pract 2018 05 6;214(5):796-799. Epub 2018 Mar 6.

Department of Pathology and Clinical Laboratory, National Cancer Center Hospital, Tokyo, Japan; Department of Pathology and Laboratory Medicine, Kansai Medical University, Osaka, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2018.03.006DOI Listing
May 2018

Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response.

Sci Rep 2018 02 22;8(1):3482. Epub 2018 Feb 22.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, 277-8562, Japan.

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http://dx.doi.org/10.1038/s41598-018-21161-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823859PMC
February 2018

Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer.

Mol Clin Oncol 2018 Feb 12;8(2):310-314. Epub 2017 Dec 12.

Department of Cellular and Organ Pathology, Graduate School of Medicine, Akita University, Akita, Akita 010-8543, Japan.

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http://dx.doi.org/10.3892/mco.2017.1536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776411PMC
February 2018

Long-Term Prognostic Significance of Plasma B-Type Natriuretic Peptide Level in Patients With Acute Heart Failure With Reduced, Mid-Range, and Preserved Ejection Fractions.

Am J Cardiol 2018 03 23;121(6):731-738. Epub 2017 Dec 23.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan; Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Hokkaido, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2017.12.012DOI Listing
March 2018

Implementation of "clinical sequencing" in cancer genome medicine in Japan.

Authors:
Takashi Kohno

Cancer Sci 2018 Mar 2;109(3):507-512. Epub 2018 Feb 2.

Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.

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http://doi.wiley.com/10.1111/cas.13486
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http://dx.doi.org/10.1111/cas.13486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834803PMC
March 2018

Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer.

DNA Res 2017 Dec;24(6):585-596

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/dnares/dsx027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726485PMC
December 2017

Significantly mutated genes and regulatory pathways in SCLC-a meta-analysis.

Cancer Genet 2017 Oct 7;216-217:20-28. Epub 2017 Jun 7.

Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, USA; UF Health Cancer Center, University of Florida, Gainesville, FL, USA; UF Genetics Institute, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677515PMC
October 2017

The genomic and epigenomic landscape in thymic carcinoma.

Carcinogenesis 2017 10;38(11):1084-1091

Division of Genome Biology, National Cancer Center Research Institute, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1093/carcin/bgx094DOI Listing
October 2017

Harmful impact of morphine use in acute heart failure.

J Thorac Dis 2017 Jul;9(7):1831-1834

Division of Cardiology, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://dx.doi.org/10.21037/jtd.2017.06.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542994PMC
July 2017

Ameliorating the severity of sleep-disordered breathing concomitant with heart failure status after percutaneous transluminal septal myocardial ablation for drug-refractory hypertrophic obstructive cardiomyopathy.

Heart Vessels 2017 Nov 29;32(11):1320-1326. Epub 2017 May 29.

Department of Cardiology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, 160-8582, Japan.

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http://dx.doi.org/10.1007/s00380-017-0997-0DOI Listing
November 2017

Author's reply: Assessment of current use of guideline-based medical therapy in elderly patients with heart failure.

Int J Cardiol 2017 09 6;242:35. Epub 2017 May 6.

Division of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2017.05.017DOI Listing
September 2017

Potential palliative care quality indicators in heart disease patients: A review of the literature.

J Cardiol 2017 Oct 17;70(4):335-341. Epub 2017 Apr 17.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2017.02.010DOI Listing
October 2017

The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine.

Nucleic Acids Res 2017 May;45(9):5231-5242

The Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo náměstí 2, 166 10 Praha, Czech Republic.

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http://dx.doi.org/10.1093/nar/gkx157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435939PMC
May 2017

Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy.

Surg Today 2018 Jan 9;48(1):1-8. Epub 2017 Mar 9.

Division of Genome Biology, National Cancer Center Research Institute, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 1040045, Japan.

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http://dx.doi.org/10.1007/s00595-017-1497-7DOI Listing
January 2018