Takashi Akamizu

Takashi Akamizu

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Takashi Akamizu

Publications by authors named "Takashi Akamizu"

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Diagnosis and treatment of autoimmune and IgG4-related hypophysitis: clinical guidelines of the Japan Endocrine Society.

Endocr J 2020 Feb 7. Epub 2020 Feb 7.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ19-0569DOI Listing
February 2020

Clinical characteristics of insulin resistance syndromes: A nationwide survey in Japan.

J Diabetes Investig 2019 Nov 2. Epub 2019 Nov 2.

Department of Metabolism and Diabetes, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1111/jdi.13171DOI Listing
November 2019

Acylated ghrelin levels were associated with depressive status, physical quality of life, endoscopic findings based on Kyoto classification in Japan.

J Clin Biochem Nutr 2019 Jul 18;65(1):65-70. Epub 2019 May 18.

Department of Internal Medicine, Division of Gastroenterology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.

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http://dx.doi.org/10.3164/jcbn.18-111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667386PMC
July 2019

Rapidly Progressing Pituitary Mass in B-cell Lymphoma.

Intern Med 2019 May 1;58(10):1525-1526. Epub 2019 Feb 1.

The First Department of Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.1576-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548916PMC
May 2019

[Endocrine Organ Dysfunction with Immune-Checkpoint Inhibitors].

Gan To Kagaku Ryoho 2018 Jul;45(7):1031-1035

The First Dept. of Medicine, Dept. of Diabetes, Endocrinology and Metabolism, Wakayama Medical University.

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July 2018

Current Status and Issues Regarding Transitional Health Care for Adults and Young Adults with Special Health Care Needs in Japan.

Intern Med 2018 May 27;57(10):1337-1344. Epub 2017 Dec 27.

The First Department of Internal Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.9740-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995699PMC
May 2018

The effects of inflammatory cytokines on the expression of ghrelin.

Endocr J 2017 ;64(Suppl.):S25-S26

The First Department of Medicine, Wakayama Medical University, Wakayama 841-8509, Japan.

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http://dx.doi.org/10.1507/endocrj.64.S25DOI Listing
April 2018

Thyroid Storm: A Japanese Perspective.

Authors:
Takashi Akamizu

Thyroid 2018 01 5;28(1):32-40. Epub 2017 Oct 5.

The First Department of Medicine, Wakayama Medical University , Wakayama, Japan .

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http://dx.doi.org/10.1089/thy.2017.0243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770119PMC
January 2018

Myotonic dystrophy type 1 with diabetes mellitus, mixed hypogonadism and adrenal insufficiency.

Endocrinol Diabetes Metab Case Rep 2018 18;2018. Epub 2018 Jan 18.

First Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan.

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http://dx.doi.org/10.1530/EDM-17-0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777164PMC
January 2018

Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC.

Oncotarget 2017 Oct 16;8(53):91516-91529. Epub 2017 Sep 16.

Children's Hospital Los Angeles, Children's Center for Cancer and Blood Diseases, Division of Hematology, Oncology and Blood & Marrow Transplantation, and The Saban Research Institute, Los Angeles, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.21066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710942PMC
October 2017

IL-1β directly suppress ghrelin mRNA expression in ghrelin-producing cells.

Mol Cell Endocrinol 2017 05 22;447:45-51. Epub 2017 Feb 22.

The First Department of Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.1016/j.mce.2017.02.032DOI Listing
May 2017

Hypersecretion of ACTH and PRL from pituitary adenoma in MEN1, adequately managed by medical therapy.

Endocrinol Diabetes Metab Case Rep 2017 6;2017. Epub 2017 Apr 6.

The 1st Department of Internal Medicine, Wakayama Medical University, WakayamaJapan.

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http://dx.doi.org/10.1530/EDM-17-0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404709PMC
April 2017

[Programs for Continuing Medical Education 2016: A Session: 3. Diagnosis and Treatment of Thyroid Diseases].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2017 Mar;106(3):472-6

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March 2017

2016 Guidelines for the management of thyroid storm from The Japan Thyroid Association and Japan Endocrine Society (First edition).

Endocr J 2016 Dec 15;63(12):1025-1064. Epub 2016 Oct 15.

Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ16-0336DOI Listing
December 2016

Physiological significance of ghrelin revealed by studies using genetically engineered mouse models with modifications in the ghrelin system.

Endocr J 2015 31;62(11):953-63. Epub 2015 Jul 31.

The First Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0361DOI Listing
September 2016

Changes in Energy Metabolism after Continuous Positive Airway Pressure for Obstructive Sleep Apnea.

Am J Respir Crit Care Med 2016 09;194(6):729-38

3 Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan; and the.

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http://dx.doi.org/10.1164/rccm.201511-2314OCDOI Listing
September 2016

Thyrotropin Receptor Epitope and Human Leukocyte Antigen in Graves' Disease.

Front Endocrinol (Lausanne) 2016 23;7:120. Epub 2016 Aug 23.

The First Department of Medicine, Wakayama Medical University , Wakayama , Japan.

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http://dx.doi.org/10.3389/fendo.2016.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994058PMC
September 2016

Clinicopathological features of Riedel's thyroiditis associated with IgG4-related disease in Japan.

Endocr J 2015 7;62(8):725-31. Epub 2015 Jul 7.

The 1st Department of Internal Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0175DOI Listing
June 2016

High incorporation of long-chain fatty acids contributes to the efficient production of acylated ghrelin in ghrelin-producing cells.

FEBS Lett 2016 Apr 22;590(7):992-1001. Epub 2016 Mar 22.

Medical Innovation Center, Kyoto University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1002/1873-3468.12132DOI Listing
April 2016

[Endocrine and Metabolic Emergencies; Points of Initial Management. Topics: III. Thyroid storm].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2016 Apr;105(4):653-7

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http://dx.doi.org/10.2169/naika.105.653DOI Listing
April 2016

A novel immunopathological association of IgG4-RD and vasculitis with Hashimoto's thyroiditis.

Endocrinol Diabetes Metab Case Rep 2016 19;2016:160004. Epub 2016 Feb 19.

The First Department of Medicine, Wakayama Medical University , 811-1, Kimiidera, Wakayama, 641-8509 , Japan.

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http://dx.doi.org/10.1530/EDM-16-0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785346PMC
March 2016

Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells.

Endocrinology 2016 Feb 15;157(2):692-704. Epub 2015 Dec 15.

Medical Innovation Center (H.I., K.D., M.B., T.K., C.S., K.H., K.K., K.N.) and Departments of Diabetes, Endocrinology, and Nutrition (H.K.) and Human Health Sciences (K.H.), Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan; National Cerebral and Cardiovascular Center Research Institute (H.H., K.K.), Osaka 565-8565; Japan; and The First Department of Medicine (H.A., T.A.), Wakayama Medical University, Wakayama 641-8509, Japan.

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http://dx.doi.org/10.1210/en.2015-1784DOI Listing
February 2016

Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice.

Diabetologia 2015 Aug 14;58(8):1868-76. Epub 2015 May 14.

Department of Anatomy and Neurobiology, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.

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http://dx.doi.org/10.1007/s00125-015-3613-9DOI Listing
August 2015

Reduction in circulating ghrelin concentration after maturation does not affect food intake.

Endocr J 2014 17;61(10):1041-52. Epub 2014 Jul 17.

Department of Endocrinology and Metabolism, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1507/endocrj.ej14-0255DOI Listing
June 2015

Management of hyperthyroidism during pregnancy in Asia.

Endocr J 2014 22;61(8):751-8. Epub 2014 May 22.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1507/endocrj.ej14-0145DOI Listing
May 2015

Screening and management of hypothyroidism in pregnancy: results of an Asian survey.

Endocr J 2014 14;61(7):697-704. Epub 2014 May 14.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1507/endocrj.ej14-0083DOI Listing
April 2015

Overexpression of intraislet ghrelin enhances β-cell proliferation after streptozotocin-induced β-cell injury in mice.

Am J Physiol Endocrinol Metab 2013 Jul 7;305(1):E140-8. Epub 2013 May 7.

Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1152/ajpendo.00112.2013DOI Listing
July 2013

Ultrasonographic thyroid nodular findings in Japanese children.

J Med Ultrason (2001) 2013 Jul 18;40(3):219-24. Epub 2013 May 18.

Department of Global Health, Medicine and Welfare, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.

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http://dx.doi.org/10.1007/s10396-013-0456-1DOI Listing
July 2013

Epitope recognition in HLA-DR3 transgenic mice immunized to TSH-R protein or peptides.

Endocrinology 2013 Jun 16;154(6):2234-43. Epub 2013 Apr 16.

Department of Cellular and Molecular Biology, University of Rhode Island, Kingston, Rhode Island 02881, USA.

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http://dx.doi.org/10.1210/en.2013-1033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393327PMC
June 2013

Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma.

Cancer Med 2013 Jun 2;2(3):286-95. Epub 2013 Apr 2.

Institute of Medicinal Chemistry, Hoshi University, Ebara 2-4-41, Shinagawa-ku, Tokyo, 142-8501, Japan.

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http://dx.doi.org/10.1002/cam4.76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699840PMC
June 2013

[Programs for continuing medical education: a session; 5. Recent advances in the management of thyroid disorders].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2013 Mar;102(3):618-23

The First Department of Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.2169/naika.102.618DOI Listing
March 2013

Transgenic mice overexpressing ghrelin or ghrelin analog.

Methods Enzymol 2012 ;514:371-7

Department of Endocrinology and Metabolism, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/B978-0-12-381272-8.00023-4DOI Listing
February 2013

Therapeutic potential of ghrelin in restricting-type anorexia nervosa.

Methods Enzymol 2012 ;514:381-98

Health Services Center, National Graduate Institute for Policy Studies, Tokyo, Japan.

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http://dx.doi.org/10.1016/B978-0-12-381272-8.00024-6DOI Listing
February 2013

Growth stimulating antibody, as another predisposing factor of Graves' disease (GD): analysis using monoclonal TSH receptor antibodies derived from patients with GD.

Endocr J 2012 18;59(7):571-7. Epub 2012 May 18.

Department of General Medicine, National Defense Medical College, Tokorozawa 359-8513, Japan.

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http://dx.doi.org/10.1507/endocrj.ej11-0348DOI Listing
January 2013

[Series: clinical study from Japan and its reflections; clinical study on the application of ghrelin to management of patients undergoing total hip replacement].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2013 Jan;102(1):174-8

First Department of Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.2169/naika.102.174DOI Listing
January 2013

[Diagnosis and treatment of thyroid storm].

Authors:
Takashi Akamizu

Nihon Rinsho 2012 Nov;70(11):2000-4

First Department of Medicine, Wakayama Medical University.

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November 2012

Adrenal tumor volume in a genetically engineered mouse model of neuroblastoma determined by magnetic resonance imaging.

Exp Ther Med 2012 Jul 2;4(1):61-64. Epub 2012 May 2.

Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo 142-8501;

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http://dx.doi.org/10.3892/etm.2012.564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460253PMC
July 2012

Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report.

Med Princ Pract 2012 17;21(2):190-2. Epub 2011 Nov 17.

Department of Aging Medicine and Geriatrics, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1159/000333697DOI Listing
June 2012

A case of liver abscess caused by Edwardsiella tarda.

Intern Med 2011 1;50(13):1439-42. Epub 2011 Jul 1.

The First Department of Medicine, Wakayama Medical University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.50.5297DOI Listing
May 2012

The physiological significance and potential clinical applications of ghrelin.

Eur J Intern Med 2012 Apr 30;23(3):197-202. Epub 2011 Dec 30.

Ghrelin Research Project, Department of Experimental Therapeutics, Translational Research Center, Kyoto University Hospital, Kyoto University School of Medicine, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.ejim.2011.12.001DOI Listing
April 2012

Functional polymorphisms in TBX21 and HLX are associated with development and prognosis of Graves' disease.

Autoimmunity 2012 Mar 21;45(2):129-36. Epub 2011 Oct 21.

Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.3109/08916934.2011.622013DOI Listing
March 2012

Analysis of plasma ghrelin in patients with medium-chain acyl-CoA dehydrogenase deficiency and glutaric aciduria type II.

Eur J Endocrinol 2012 Feb 2;166(2):235-40. Epub 2011 Nov 2.

The First Department of Medicine, Wakayama Medical University, 811-1 Kimi-idera, Wakayama 641-8509, Japan.

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https://eje.bioscientifica.com/view/journals/eje/166/2/235.x
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http://dx.doi.org/10.1530/EJE-11-0785DOI Listing
February 2012

Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo.

Am J Physiol Endocrinol Metab 2012 Feb 22;302(4):E403-8. Epub 2011 Nov 22.

Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://www.physiology.org/doi/10.1152/ajpendo.00341.2011
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http://dx.doi.org/10.1152/ajpendo.00341.2011DOI Listing
February 2012

Therapeutic applications of ghrelin to cachexia utilizing its appetite-stimulating effect.

Peptides 2011 Nov 23;32(11):2295-300. Epub 2011 May 23.

The First Department of Medicine, Wakayama Medical University, Wakayama 641-8509, Japan.

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http://dx.doi.org/10.1016/j.peptides.2011.05.018DOI Listing
November 2011

Successful treatment of protein-losing gastroenteropathy with steroid pulse and immunosuppressive therapies in a patient with sjögren syndrome.

Case Rep Gastroenterol 2011 8;5(2):372-7. Epub 2011 Jul 8.

Department of Internal Medicine, Naga Municipal Hospital, Kinokawa, Wakayama Medical University, Wakayama, Japan.

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http://dx.doi.org/10.1159/000330197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134061PMC
November 2011

Ghrelin and functional dyspepsia.

Int J Pept 2010 12;2010. Epub 2010 Jan 12.

Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto University School of Medicine, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1155/2010/548457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915802PMC
July 2011

Oxytocin and dopamine stimulate ghrelin secretion by the ghrelin-producing cell line, MGN3-1 in vitro.

Endocrinology 2011 Jul 26;152(7):2619-25. Epub 2011 Apr 26.

Ghrelin Research Project, Translational Research Center, Kyoto University Hospital, Kyoto, Japan.

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http://dx.doi.org/10.1210/en.2010-1455DOI Listing
July 2011

[Translational research on ghrelin].

Authors:
Takashi Akamizu

Nihon Yakurigaku Zasshi 2011 Feb;137(2):83-5

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http://dx.doi.org/10.1254/fpj.137.83DOI Listing
February 2011

Generation of transgenic mice overexpressing a ghrelin analog.

Endocrinology 2010 Dec 20;151(12):5935-40. Epub 2010 Oct 20.

Department of Endocrinology and Metabolism, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1210/en.2010-0635DOI Listing
December 2010

Ghrelin for cachexia.

J Cachexia Sarcopenia Muscle 2010 Dec 17;1(2):169-176. Epub 2010 Dec 17.

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http://dx.doi.org/10.1007/s13539-010-0011-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060649PMC
December 2010

[Therapy-resistant thyroid diseases. 2. Thyrotoxic crises].

Authors:
Takashi Akamizu

Nihon Naika Gakkai Zasshi 2010 Apr;99(4):763-8

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http://dx.doi.org/10.2169/naika.99.763DOI Listing
April 2010