Takamitsu Sano

Takamitsu Sano

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Takamitsu Sano

Takamitsu Sano

Publications by authors named "Takamitsu Sano"

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18Publications

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Loss of GPRC5B impairs synapse formation of Purkinje cells with cerebellar nuclear neurons and disrupts cerebellar synaptic plasticity and motor learning.

Neurosci Res 2018 Nov 23;136:33-47. Epub 2018 Feb 23.

Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2018.02.006DOI Listing
November 2018

Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane.

Mol Biol Cell 2018 05 22;29(10):1203-1218. Epub 2018 Mar 22.

Division of Molecular Interaction, Institute for Genetic Medicine, Hokkaido University Graduate School of Life Science, Kita-ku, Sapporo 060-0815, Japan.

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http://dx.doi.org/10.1091/mbc.E17-04-0217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935070PMC
May 2018

Inositol depletion restores vesicle transport in yeast phospholipid flippase mutants.

PLoS One 2015 17;10(3):e0120108. Epub 2015 Mar 17.

Division of Molecular Interaction, Institute for Genetic Medicine, Hokkaido University Graduate School of Life Science, Sapporo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120108PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363822PMC
December 2015

GPRC5B activates obesity-associated inflammatory signaling in adipocytes.

Sci Signal 2012 Nov 20;5(251):ra85. Epub 2012 Nov 20.

Laboratory for Molecular Membrane Neuroscience, RIKEN Brain Science Institute, Hirosawa 2-1, Wako-shi, Saitama 351-0198, Japan.

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http://stke.sciencemag.org/cgi/doi/10.1126/scisignal.2003149
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http://dx.doi.org/10.1126/scisignal.2003149DOI Listing
November 2012

Comparative characterization of GPRC5B and GPRC5CLacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice.

Biochem Biophys Res Commun 2011 Sep 5;412(3):460-5. Epub 2011 Aug 5.

Laboratory for Molecular Membrane Neuroscience, Brain Science Institute, RIKEN, Wako-shi, Saitama 351-0198, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.07.118DOI Listing
September 2011

Intracellular trafficking pathway of yeast long-chain base kinase Lcb4, from its synthesis to its degradation.

J Biol Chem 2007 Sep 8;282(39):28485-92. Epub 2007 Aug 8.

Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M701607200
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http://dx.doi.org/10.1074/jbc.M701607200DOI Listing
September 2007

Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes.

Biochem Biophys Res Commun 2007 May 28;357(1):212-7. Epub 2007 Mar 28.

Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0700607
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http://dx.doi.org/10.1016/j.bbrc.2007.03.123DOI Listing
May 2007

Changes in S1P1 and S1P2 expression during embryonal development and primitive endoderm differentiation of F9 cells.

Biochem Biophys Res Commun 2006 Jun 19;344(3):852-8. Epub 2006 Apr 19.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0600797
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http://dx.doi.org/10.1016/j.bbrc.2006.04.002DOI Listing
June 2006

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

Biochim Biophys Acta 2006 Apr 7;1761(4):474-83. Epub 2006 Apr 7.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://dx.doi.org/10.1016/j.bbalip.2006.03.010DOI Listing
April 2006

Sphingosine 1-phosphate is released from the cytosol of rat platelets in a carrier-mediated manner.

J Lipid Res 2006 Mar 21;47(3):614-21. Epub 2005 Dec 21.

Department of Cell Membrane Biology, Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M500468-JLR200
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http://dx.doi.org/10.1194/jlr.M500468-JLR200DOI Listing
March 2006

Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets.

J Lipid Res 2005 Nov 1;46(11):2458-67. Epub 2005 Aug 1.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://dx.doi.org/10.1194/jlr.M500268-JLR200DOI Listing
November 2005

Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants.

J Biol Chem 2005 Nov 1;280(44):36674-82. Epub 2005 Sep 1.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://dx.doi.org/10.1074/jbc.M503147200DOI Listing
November 2005

Long-chain base kinase Lcb4 Is anchored to the membrane through its palmitoylation by Akr1.

Mol Cell Biol 2005 Nov;25(21):9189-97

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://dx.doi.org/10.1128/MCB.25.21.9189-9197.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1265802PMC
November 2005

Phosphorylation by Pho85 cyclin-dependent kinase acts as a signal for the down-regulation of the yeast sphingoid long-chain base kinase Lcb4 during the stationary phase.

J Biol Chem 2005 Feb 14;280(8):6520-7. Epub 2004 Dec 14.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M410908200
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http://dx.doi.org/10.1074/jbc.M410908200DOI Listing
February 2005

Transmembrane topology of sphingoid long-chain base-1-phosphate phosphatase, Lcb3p.

Genes Cells 2003 Jun;8(6):525-35

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita 12-jo, Nishi 6-choume, Kita-ku, Sapporo 060-0812, Japan.

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June 2003

Synthesis of fluorescence-labeled sphingosine and sphingosine 1-phosphate; effective tools for sphingosine and sphingosine 1-phosphate behavior.

Bioorg Med Chem Lett 2003 Feb;13(4):661-4

School of Science and Technology, Kwansei Gakuin University, Gakuen, Sanda, Hyogo 669-1337, Japan.

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http://dx.doi.org/10.1016/s0960-894x(02)00999-xDOI Listing
February 2003

Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

J Biol Chem 2002 Jun 2;277(24):21197-206. Epub 2002 Apr 2.

Department of Biomembrane and Biofunctional Chemistry, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 06-0812, Japan.

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http://dx.doi.org/10.1074/jbc.M201289200DOI Listing
June 2002