Takamitsu Miyafusa

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Takamitsu Miyafusa

Publications by authors named "Takamitsu Miyafusa"

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13Publications

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Structural insights into the backbone-circularized granulocyte colony-stimulating factor containing a short connector.

Biochem Biophys Res Commun 2018 Jun 17;500(2):224-228. Epub 2018 Apr 17.

Biomedical Research Institute, The National Institute of Advanced Industrial Science and Technology, Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan. Electronic address:

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June 2018

Backbone Circularization Coupled with Optimization of Connecting Segment in Effectively Improving the Stability of Granulocyte-Colony Stimulating Factor.

ACS Chem Biol 2017 10 27;12(10):2690-2696. Epub 2017 Sep 27.

Biomedical Research Institute, The National Institute of Advanced Industrial Science and Technology , Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan.

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October 2017

AlphaScreen-based homogeneous assay using a pair of 25-residue artificial proteins for high-throughput analysis of non-native IgG.

Sci Rep 2017 Sep 29;7(1):12466. Epub 2017 Sep 29.

Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8566, Japan.

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September 2017

Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin.

Sci Rep 2017 01 3;7:39518. Epub 2017 Jan 3.

Department of Chemistry &Biotechnology, School of Engineering, The University of Tokyo, Tokyo 108-8639, Japan.

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January 2017

Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.

Sci Rep 2015 Oct 16;5:15337. Epub 2015 Oct 16.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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October 2015

Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus.

FEBS Lett 2013 Nov 21;587(23):3824-30. Epub 2013 Oct 21.

Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan; Department of Medical Genome Sciences, School of Frontier Sciences, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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November 2013

Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus.

Biosci Rep 2013 Jun 11;33(3). Epub 2013 Jun 11.

Medical Proteomics Laboratory, Institute of Medical Science, Department of Medical Genome Sciences, School of Frontier Sciences, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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June 2013

Identification of small-molecule inhibitors of the human S100B-p53 interaction and evaluation of their activity in human melanoma cells.

Bioorg Med Chem 2013 Mar 8;21(5):1109-15. Epub 2013 Jan 8.

Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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March 2013

Crystal structure of the C-terminal domain of Mu phage central spike and functions of bound calcium ion.

Biochim Biophys Acta 2013 Jan 24;1834(1):284-91. Epub 2012 Aug 24.

Institute for Protein Research, Osaka University, 3-2 Yamada-oka, Suita, Osaka 565-0871, Japan.

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January 2013

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin.

Mol Biosyst 2012 Aug 7;8(8):2050-3. Epub 2012 Jun 7.

Department of Medical Genome Sciences, The University of Tokyo, Tokyo 108-8639, Japan.

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August 2012

Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.

Biochem J 2012 May;443(3):671-80

Department of Medical Genome Science, School of Frontier Sciences, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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May 2012

Expression, purification, crystallization and preliminary diffraction analysis of CapF, a capsular polysaccharide-synthesis enzyme from Staphylococcus aureus.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 Jun 23;64(Pt 6):512-5. Epub 2008 May 23.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 277-8562, Japan.

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June 2008