Takahisa Kawaguchi

Takahisa Kawaguchi

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Takahisa Kawaguchi

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Lifestyle habits associated with nocturnal urination frequency: The Nagahama study.

Neurourol Urodyn 2019 Nov 4;38(8):2359-2367. Epub 2019 Sep 4.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1002/nau.24156DOI Listing
November 2019

Association of the spot urine sodium-to-potassium ratio with blood pressure is independent of urinary Na and K levels: The Nagahama study.

Hypertens Res 2019 Oct 10;42(10):1624-1630. Epub 2019 Jun 10.

Department of Human Health Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41440-019-0276-9DOI Listing
October 2019

Expanding Phenotype of Nephronophthisis-Related Ciliopathy: an Elderly Patient with Homozygous RPGRIP1L Mutation.

Nephron 2018 10;140(1):74-78. Epub 2018 Jul 10.

Apheresis and Dialysis Center, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1159/000490770DOI Listing
September 2019

Association between sleep disturbance and nocturnal blood pressure profiles by a linear mixed model analysis: the Nagahama study.

Sleep Med 2019 Sep 5;61:104-109. Epub 2019 Mar 5.

Department of Respiratory Care and Sleep Control Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.sleep.2019.01.049DOI Listing
September 2019

Sleep Disturbance Worsens Lower Urinary Tract Symptoms: The Nagahama Study.

J Urol 2019 08 8;202(2):354. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://dx.doi.org/10.1097/JU.0000000000000212DOI Listing
August 2019

Reply by Authors.

J Urol 2019 08 8;202(2):360-361. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://www.jurology.com/doi/10.1097/01.JU.0000559826.09631.1
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http://dx.doi.org/10.1097/01.JU.0000559826.09631.1dDOI Listing
August 2019

Establishment of a Comprehensive Information Infrastructure and a Support Organization for Rare Disease Research in Japan (RADDAR-J).

Stud Health Technol Inform 2019 Aug;264:1080-1083

Center for Genomic Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.3233/SHTI190391DOI Listing
August 2019

Association between socioeconomic factors and urinary sodium-to-potassium ratio: the Nagahama Study.

Hypertens Res 2018 Nov 14;41(11):973-980. Epub 2018 Sep 14.

Department of Human Health Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://www.nature.com/articles/s41440-018-0101-x
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http://dx.doi.org/10.1038/s41440-018-0101-xDOI Listing
November 2018

Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study.

Clin Exp Hypertens 2018 23;40(4):363-369. Epub 2017 Oct 23.

o Department of Planning for Drug Development and Clinical Evaluation , Tohoku University Graduate School of Pharmaceutical Sciences , Sendai , Japan.

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http://dx.doi.org/10.1080/10641963.2017.1384481DOI Listing
August 2018

Self-reported quality of sleep is associated with physical strength among community-dwelling young-old adults.

Geriatr Gerontol Int 2017 Nov 6;17(11):1808-1813. Epub 2017 Jan 6.

Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1111/ggi.12965DOI Listing
November 2017

Prognostic Significance of Spot Urine Na/K for Longitudinal Changes in Blood Pressure and Renal Function: The Nagahama Study.

Am J Hypertens 2017 Sep;30(9):899-906

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1093/ajh/hpx075DOI Listing
September 2017

Are there different factors affecting walking speed and gait cycle variability between men and women in community-dwelling older adults?

Aging Clin Exp Res 2017 Apr 11;29(2):215-221. Epub 2016 Apr 11.

Human Health Science, Kyoto University Graduate School of Medicine, 53 Kawahara-cho, Shogoin, Sakyo, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s40520-016-0568-8DOI Listing
April 2017

Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study.

Medicine (Baltimore) 2016 Apr;95(15):e3371

From the Department of Respiratory Medicine (SM, HM, II, YI, KM, MM); Center for Genomic Medicine, Kyoto University Graduate School of Medicine (YT, KS, TK, MT, CT, RY, FM); Department of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto (SK); Center for Preventive Medical Science, Chiba University, Chiba (AS); Department of Health Informatics, Kyoto University School of Public Health (TN); and Department of Respiratory Care and Sleep Control Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (KC).

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http://dx.doi.org/10.1097/MD.0000000000003371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839845PMC
April 2016

Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study.

J Hypertens 2015 Dec;33(12):2407-13

aCenter for Genomic Medicine, Kyoto University Graduate School of Medicine bDepartment of Health Informatics, Kyoto University School of Public Health cDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine dDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto eCenter for Preventive Medical Science, Chiba University, Chiba, Japan.

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http://pdfs.journals.lww.com/jhypertension/2015/12000/Descri
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http://dx.doi.org/10.1097/HJH.0000000000000734DOI Listing
December 2015

Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.

J Gastroenterol 2015 Aug 26;50(8):887-93. Epub 2014 Nov 26.

Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s00535-014-1018-zDOI Listing
August 2015

Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels.

Nat Commun 2015 Jul 15;6:7754. Epub 2015 Jul 15.

1] Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi 53, Sakyo-ku, Kyoto 606-8507, Japan. [2] Statistical Genetics, Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi 53, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1038/ncomms8754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518310PMC
July 2015

Central blood pressure relates more strongly to retinal arteriolar narrowing than brachial blood pressure: the Nagahama Study.

J Hypertens 2015 Feb;33(2):323-9

aDepartment of Ophthalmology and Visual Sciences bCenter for Genomic Medicine, Kyoto University Graduate School of Medicine cDepartment of Health Informatics dDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health eKyoto University Medical Research Support Center, Kyoto, Japan.

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http://dx.doi.org/10.1097/HJH.0000000000000391DOI Listing
February 2015

The KSS 2011 reflects symptoms, physical activities, and radiographic grades in a Japanese population.

Clin Orthop Relat Res 2015 Jan;473(1):70-5

Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto, 606-8507, Japan.

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http://link.springer.com/10.1007/s11999-014-3650-6
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http://dx.doi.org/10.1007/s11999-014-3650-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390913PMC
January 2015

Association of serum-free fatty acid level with reduced reflection pressure wave magnitude and central blood pressure: the Nagahama study.

Hypertension 2014 Dec 8;64(6):1212-8. Epub 2014 Sep 8.

From the Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (Y.T., T.K., K.S., C.T., R.Y., F.M.); Departments of Health Informatics (Y.T., T.N.) and Medical Ethics and Medical Genetics (S.K.), Kyoto University School of Public Health, Kyoto, Japan; and Kyoto University Medical Research Support Center, Kyoto, Japan (A.S.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.114.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04277DOI Listing
December 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Nature 2014 Feb 25;506(7488):376-81. Epub 2013 Dec 25.

1] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944098PMC
February 2014

Airflow limitation in smokers is associated with arterial stiffness: the Nagahama Study.

Atherosclerosis 2014 Jan 1;232(1):59-64. Epub 2013 Nov 1.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.10.020DOI Listing
January 2014

[Development of pharmacogenomics--guided tailored therapy for colorectal cancer].

Nihon Rinsho 2014 Jan;72(1):23-8

Department of Genomic Epidemiology, Graduate School of Medicine, Kyoto University.

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January 2014

Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy.

Invest Ophthalmol Vis Sci 2013 Sep 9;54(9):6068-73. Epub 2013 Sep 9.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.13-11605DOI Listing
September 2013

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.

Cancer Sci 2011 Jan 28;102(1):245-52. Epub 2010 Sep 28.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01737.xDOI Listing
January 2011

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.

Nat Genet 2010 Sep 15;42(9):768-71. Epub 2010 Aug 15.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://www.nature.com/articles/ng.645
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http://dx.doi.org/10.1038/ng.645DOI Listing
September 2010

Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables.

Genet Epidemiol 2010 Sep;34(6):543-51

Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1002/gepi.20510DOI Listing
September 2010

Population-genetic nature of copy number variations in the human genome.

Hum Mol Genet 2010 Mar 5;19(5):761-73. Epub 2009 Dec 5.

Center for Genomic Medicine, RIKEN, 1-7-22 Suehiro, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1093/hmg/ddp541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816609PMC
March 2010

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.

Gastroenterology 2009 Nov 19;137(5):1768-75. Epub 2009 Aug 19.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1053/j.gastro.2009.07.070DOI Listing
November 2009

A second generation human haplotype map of over 3.1 million SNPs.

Authors:
Kelly A Frazer Dennis G Ballinger David R Cox David A Hinds Laura L Stuve Richard A Gibbs John W Belmont Andrew Boudreau Paul Hardenbol Suzanne M Leal Shiran Pasternak David A Wheeler Thomas D Willis Fuli Yu Huanming Yang Changqing Zeng Yang Gao Haoran Hu Weitao Hu Chaohua Li Wei Lin Siqi Liu Hao Pan Xiaoli Tang Jian Wang Wei Wang Jun Yu Bo Zhang Qingrun Zhang Hongbin Zhao Hui Zhao Jun Zhou Stacey B Gabriel Rachel Barry Brendan Blumenstiel Amy Camargo Matthew Defelice Maura Faggart Mary Goyette Supriya Gupta Jamie Moore Huy Nguyen Robert C Onofrio Melissa Parkin Jessica Roy Erich Stahl Ellen Winchester Liuda Ziaugra David Altshuler Yan Shen Zhijian Yao Wei Huang Xun Chu Yungang He Li Jin Yangfan Liu Yayun Shen Weiwei Sun Haifeng Wang Yi Wang Ying Wang Xiaoyan Xiong Liang Xu Mary M Y Waye Stephen K W Tsui Hong Xue J Tze-Fei Wong Luana M Galver Jian-Bing Fan Kevin Gunderson Sarah S Murray Arnold R Oliphant Mark S Chee Alexandre Montpetit Fanny Chagnon Vincent Ferretti Martin Leboeuf Jean-François Olivier Michael S Phillips Stéphanie Roumy Clémentine Sallée Andrei Verner Thomas J Hudson Pui-Yan Kwok Dongmei Cai Daniel C Koboldt Raymond D Miller Ludmila Pawlikowska Patricia Taillon-Miller Ming Xiao Lap-Chee Tsui William Mak You Qiang Song Paul K H Tam Yusuke Nakamura Takahisa Kawaguchi Takuya Kitamoto Takashi Morizono Atsushi Nagashima Yozo Ohnishi Akihiro Sekine Toshihiro Tanaka Tatsuhiko Tsunoda Panos Deloukas Christine P Bird Marcos Delgado Emmanouil T Dermitzakis Rhian Gwilliam Sarah Hunt Jonathan Morrison Don Powell Barbara E Stranger Pamela Whittaker David R Bentley Mark J Daly Paul I W de Bakker Jeff Barrett Yves R Chretien Julian Maller Steve McCarroll Nick Patterson Itsik Pe'er Alkes Price Shaun Purcell Daniel J Richter Pardis Sabeti Richa Saxena Stephen F Schaffner Pak C Sham Patrick Varilly David Altshuler Lincoln D Stein Lalitha Krishnan Albert Vernon Smith Marcela K Tello-Ruiz Gudmundur A Thorisson Aravinda Chakravarti Peter E Chen David J Cutler Carl S Kashuk Shin Lin Gonçalo R Abecasis Weihua Guan Yun Li Heather M Munro Zhaohui Steve Qin Daryl J Thomas Gilean McVean Adam Auton Leonardo Bottolo Niall Cardin Susana Eyheramendy Colin Freeman Jonathan Marchini Simon Myers Chris Spencer Matthew Stephens Peter Donnelly Lon R Cardon Geraldine Clarke David M Evans Andrew P Morris Bruce S Weir Tatsuhiko Tsunoda James C Mullikin Stephen T Sherry Michael Feolo Andrew Skol Houcan Zhang Changqing Zeng Hui Zhao Ichiro Matsuda Yoshimitsu Fukushima Darryl R Macer Eiko Suda Charles N Rotimi Clement A Adebamowo Ike Ajayi Toyin Aniagwu Patricia A Marshall Chibuzor Nkwodimmah Charmaine D M Royal Mark F Leppert Missy Dixon Andy Peiffer Renzong Qiu Alastair Kent Kazuto Kato Norio Niikawa Isaac F Adewole Bartha M Knoppers Morris W Foster Ellen Wright Clayton Jessica Watkin Richard A Gibbs John W Belmont Donna Muzny Lynne Nazareth Erica Sodergren George M Weinstock David A Wheeler Imtaz Yakub Stacey B Gabriel Robert C Onofrio Daniel J Richter Liuda Ziaugra Bruce W Birren Mark J Daly David Altshuler Richard K Wilson Lucinda L Fulton Jane Rogers John Burton Nigel P Carter Christopher M Clee Mark Griffiths Matthew C Jones Kirsten McLay Robert W Plumb Mark T Ross Sarah K Sims David L Willey Zhu Chen Hua Han Le Kang Martin Godbout John C Wallenburg Paul L'Archevêque Guy Bellemare Koji Saeki Hongguang Wang Daochang An Hongbo Fu Qing Li Zhen Wang Renwu Wang Arthur L Holden Lisa D Brooks Jean E McEwen Mark S Guyer Vivian Ota Wang Jane L Peterson Michael Shi Jack Spiegel Lawrence M Sung Lynn F Zacharia Francis S Collins Karen Kennedy Ruth Jamieson John Stewart

Nature 2007 Oct;449(7164):851-61

The Scripps Research Institute, 10550 North Torrey Pines Road MEM275, La Jolla, California 92037, USA.

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https://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/In
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http://www.nature.com/doifinder/10.1038/nature06258
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http://dx.doi.org/10.1038/nature06258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689609PMC
October 2007

Genome-wide detection and characterization of positive selection in human populations.

Authors:
Pardis C Sabeti Patrick Varilly Ben Fry Jason Lohmueller Elizabeth Hostetter Chris Cotsapas Xiaohui Xie Elizabeth H Byrne Steven A McCarroll Rachelle Gaudet Stephen F Schaffner Eric S Lander Kelly A Frazer Dennis G Ballinger David R Cox David A Hinds Laura L Stuve Richard A Gibbs John W Belmont Andrew Boudreau Paul Hardenbol Suzanne M Leal Shiran Pasternak David A Wheeler Thomas D Willis Fuli Yu Huanming Yang Changqing Zeng Yang Gao Haoran Hu Weitao Hu Chaohua Li Wei Lin Siqi Liu Hao Pan Xiaoli Tang Jian Wang Wei Wang Jun Yu Bo Zhang Qingrun Zhang Hongbin Zhao Hui Zhao Jun Zhou Stacey B Gabriel Rachel Barry Brendan Blumenstiel Amy Camargo Matthew Defelice Maura Faggart Mary Goyette Supriya Gupta Jamie Moore Huy Nguyen Robert C Onofrio Melissa Parkin Jessica Roy Erich Stahl Ellen Winchester Liuda Ziaugra David Altshuler Yan Shen Zhijian Yao Wei Huang Xun Chu Yungang He Li Jin Yangfan Liu Yayun Shen Weiwei Sun Haifeng Wang Yi Wang Ying Wang Xiaoyan Xiong Liang Xu Mary M Y Waye Stephen K W Tsui Hong Xue J Tze-Fei Wong Luana M Galver Jian-Bing Fan Kevin Gunderson Sarah S Murray Arnold R Oliphant Mark S Chee Alexandre Montpetit Fanny Chagnon Vincent Ferretti Martin Leboeuf Jean-François Olivier Michael S Phillips Stéphanie Roumy Clémentine Sallée Andrei Verner Thomas J Hudson Pui-Yan Kwok Dongmei Cai Daniel C Koboldt Raymond D Miller Ludmila Pawlikowska Patricia Taillon-Miller Ming Xiao Lap-Chee Tsui William Mak You Qiang Song Paul K H Tam Yusuke Nakamura Takahisa Kawaguchi Takuya Kitamoto Takashi Morizono Atsushi Nagashima Yozo Ohnishi Akihiro Sekine Toshihiro Tanaka Tatsuhiko Tsunoda Panos Deloukas Christine P Bird Marcos Delgado Emmanouil T Dermitzakis Rhian Gwilliam Sarah Hunt Jonathan Morrison Don Powell Barbara E Stranger Pamela Whittaker David R Bentley Mark J Daly Paul I W de Bakker Jeff Barrett Yves R Chretien Julian Maller Steve McCarroll Nick Patterson Itsik Pe'er Alkes Price Shaun Purcell Daniel J Richter Pardis Sabeti Richa Saxena Stephen F Schaffner Pak C Sham Patrick Varilly David Altshuler Lincoln D Stein Lalitha Krishnan Albert Vernon Smith Marcela K Tello-Ruiz Gudmundur A Thorisson Aravinda Chakravarti Peter E Chen David J Cutler Carl S Kashuk Shin Lin Gonçalo R Abecasis Weihua Guan Yun Li Heather M Munro Zhaohui Steve Qin Daryl J Thomas Gilean McVean Adam Auton Leonardo Bottolo Niall Cardin Susana Eyheramendy Colin Freeman Jonathan Marchini Simon Myers Chris Spencer Matthew Stephens Peter Donnelly Lon R Cardon Geraldine Clarke David M Evans Andrew P Morris Bruce S Weir Tatsuhiko Tsunoda Todd A Johnson James C Mullikin Stephen T Sherry Michael Feolo Andrew Skol Houcan Zhang Changqing Zeng Hui Zhao Ichiro Matsuda Yoshimitsu Fukushima Darryl R Macer Eiko Suda Charles N Rotimi Clement A Adebamowo Ike Ajayi Toyin Aniagwu Patricia A Marshall Chibuzor Nkwodimmah Charmaine D M Royal Mark F Leppert Missy Dixon Andy Peiffer Renzong Qiu Alastair Kent Kazuto Kato Norio Niikawa Isaac F Adewole Bartha M Knoppers Morris W Foster Ellen Wright Clayton Jessica Watkin Richard A Gibbs John W Belmont Donna Muzny Lynne Nazareth Erica Sodergren George M Weinstock David A Wheeler Imtaz Yakub Stacey B Gabriel Robert C Onofrio Daniel J Richter Liuda Ziaugra Bruce W Birren Mark J Daly David Altshuler Richard K Wilson Lucinda L Fulton Jane Rogers John Burton Nigel P Carter Christopher M Clee Mark Griffiths Matthew C Jones Kirsten McLay Robert W Plumb Mark T Ross Sarah K Sims David L Willey Zhu Chen Hua Han Le Kang Martin Godbout John C Wallenburg Paul L'Archevêque Guy Bellemare Koji Saeki Hongguang Wang Daochang An Hongbo Fu Qing Li Zhen Wang Renwu Wang Arthur L Holden Lisa D Brooks Jean E McEwen Mark S Guyer Vivian Ota Wang Jane L Peterson Michael Shi Jack Spiegel Lawrence M Sung Lynn F Zacharia Francis S Collins Karen Kennedy Ruth Jamieson John Stewart

Nature 2007 Oct;449(7164):913-8

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.

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https://www.genome.gov/Pages/Newsroom/CurrentNewsReleases/Le
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http://www.nature.com/doifinder/10.1038/nature06250
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687721PMC
October 2007