Publications by authors named "Takahisa Kawaguchi"

100Publications

Genome-wide association study of individual differences of human lymphocyte profiles using large-scale cytometry data.

J Hum Genet 2020 Nov 23. Epub 2020 Nov 23.

Department of Statistical Genetics, Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1038/s10038-020-00874-xDOI Listing
November 2020

Night-time frequency of urination as a manifestation of sleep-disordered breathing: the Nagahama study.

Sleep Med 2020 Sep 12. Epub 2020 Sep 12.

Department of Respiratory Care and Sleep Control Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.sleep.2020.09.007DOI Listing
September 2020

Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer.

Nat Commun 2020 06 24;11(1):3175. Epub 2020 Jun 24.

Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, 464-8681, Japan.

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http://dx.doi.org/10.1038/s41467-020-16711-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314803PMC
June 2020

Identification of type 2 diabetes loci in 433,540 East Asian individuals.

Authors:
Cassandra N Spracklen Momoko Horikoshi Young Jin Kim Kuang Lin Fiona Bragg Sanghoon Moon Ken Suzuki Claudia H T Tam Yasuharu Tabara Soo-Heon Kwak Fumihiko Takeuchi Jirong Long Victor J Y Lim Jin-Fang Chai Chien-Hsiun Chen Masahiro Nakatochi Jie Yao Hyeok Sun Choi Apoorva K Iyengar Hannah J Perrin Sarah M Brotman Martijn van de Bunt Anna L Gloyn Jennifer E Below Michael Boehnke Donald W Bowden John C Chambers Anubha Mahajan Mark I McCarthy Maggie C Y Ng Lauren E Petty Weihua Zhang Andrew P Morris Linda S Adair Masato Akiyama Zheng Bian Juliana C N Chan Li-Ching Chang Miao-Li Chee Yii-Der Ida Chen Yuan-Tsong Chen Zhengming Chen Lee-Ming Chuang Shufa Du Penny Gordon-Larsen Myron Gross Xiuqing Guo Yu Guo Sohee Han Annie-Green Howard Wei Huang Yi-Jen Hung Mi Yeong Hwang Chii-Min Hwu Sahoko Ichihara Masato Isono Hye-Mi Jang Guozhi Jiang Jost B Jonas Yoichiro Kamatani Tomohiro Katsuya Takahisa Kawaguchi Chiea-Chuen Khor Katsuhiko Kohara Myung-Shik Lee Nanette R Lee Liming Li Jianjun Liu Andrea O Luk Jun Lv Yukinori Okada Mark A Pereira Charumathi Sabanayagam Jinxiu Shi Dong Mun Shin Wing Yee So Atsushi Takahashi Brian Tomlinson Fuu-Jen Tsai Rob M van Dam Yong-Bing Xiang Ken Yamamoto Toshimasa Yamauchi Kyungheon Yoon Canqing Yu Jian-Min Yuan Liang Zhang Wei Zheng Michiya Igase Yoon Shin Cho Jerome I Rotter Ya-Xing Wang Wayne H H Sheu Mitsuhiro Yokota Jer-Yuarn Wu Ching-Yu Cheng Tien-Yin Wong Xiao-Ou Shu Norihiro Kato Kyong-Soo Park E-Shyong Tai Fumihiko Matsuda Woon-Puay Koh Ronald C W Ma Shiro Maeda Iona Y Millwood Juyoung Lee Takashi Kadowaki Robin G Walters Bong-Jo Kim Karen L Mohlke Xueling Sim

Nature 2020 06 6;582(7811):240-245. Epub 2020 May 6.

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

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http://dx.doi.org/10.1038/s41586-020-2263-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292783PMC
June 2020

Comparison of diagnostic significance of the initial versus revised diagnostic algorithm for sarcopenia from the Asian Working Group for Sarcopenia.

Arch Gerontol Geriatr 2020 Jul - Aug;89:104071. Epub 2020 Apr 25.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.archger.2020.104071DOI Listing
November 2020

Correlates of autonomic nervous system function in a general population with special reference to HbA: The Nagahama study.

Diabetes Res Clin Pract 2020 May 31;163:108126. Epub 2020 Mar 31.

Department of Health Informatics, School of Public Health, Kyoto University, Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2020.108126DOI Listing
May 2020

Advanced Glycation End Product Accumulation is Associated with Lower Cognitive Performance in an Older General Population: The Nagahama Study.

J Alzheimers Dis 2020 ;74(3):741-746

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Sakyo-ku Kyoto, Japan.

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http://dx.doi.org/10.3233/JAD-190878DOI Listing
January 2020

Lifestyle habits associated with nocturnal urination frequency: The Nagahama study.

Neurourol Urodyn 2019 11 4;38(8):2359-2367. Epub 2019 Sep 4.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1002/nau.24156DOI Listing
November 2019

Establishment of a Comprehensive Information Infrastructure and a Support Organization for Rare Disease Research in Japan (RADDAR-J).

Stud Health Technol Inform 2019 Aug;264:1080-1083

Center for Genomic Medicine, Graduate School of Medicine, Kyoto University.

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http://dx.doi.org/10.3233/SHTI190391DOI Listing
August 2019

Association between sleep disturbance and nocturnal blood pressure profiles by a linear mixed model analysis: the Nagahama study.

Sleep Med 2019 09 5;61:104-109. Epub 2019 Mar 5.

Department of Respiratory Care and Sleep Control Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.sleep.2019.01.049DOI Listing
September 2019

Frequent nocturnal urination in older men is associated with arterial stiffness: The Nagahama study.

Hypertens Res 2019 12 9;42(12):1996-2001. Epub 2019 Aug 9.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41440-019-0309-4DOI Listing
December 2019

Association of the spot urine sodium-to-potassium ratio with blood pressure is independent of urinary Na and K levels: The Nagahama study.

Hypertens Res 2019 10 10;42(10):1624-1630. Epub 2019 Jun 10.

Department of Human Health Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41440-019-0276-9DOI Listing
October 2019

Reply by Authors.

J Urol 2019 08 8;202(2):360-361. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://www.jurology.com/doi/10.1097/01.JU.0000559826.09631.1
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http://dx.doi.org/10.1097/01.JU.0000559826.09631.1dDOI Listing
August 2019

Sleep Disturbance Worsens Lower Urinary Tract Symptoms: The Nagahama Study.

J Urol 2019 08 8;202(2):354. Epub 2019 Jul 8.

Department of Urology, Kyoto University Hospital , Kyoto , Japan.

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http://dx.doi.org/10.1097/JU.0000000000000212DOI Listing
August 2019

Association between socioeconomic factors and urinary sodium-to-potassium ratio: the Nagahama Study.

Hypertens Res 2018 Nov 14;41(11):973-980. Epub 2018 Sep 14.

Department of Human Health Science, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://www.nature.com/articles/s41440-018-0101-x
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http://dx.doi.org/10.1038/s41440-018-0101-xDOI Listing
November 2018

Expanding Phenotype of Nephronophthisis-Related Ciliopathy: an Elderly Patient with Homozygous RPGRIP1L Mutation.

Nephron 2018 10;140(1):74-78. Epub 2018 Jul 10.

Apheresis and Dialysis Center, School of Medicine, Keio University, Tokyo, Japan.

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http://dx.doi.org/10.1159/000490770DOI Listing
September 2019

Genome-wide association study for white coat effect in Japanese middle-aged to elderly people: The HOMED-BP study.

Clin Exp Hypertens 2018 23;40(4):363-369. Epub 2017 Oct 23.

o Department of Planning for Drug Development and Clinical Evaluation , Tohoku University Graduate School of Pharmaceutical Sciences , Sendai , Japan.

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http://dx.doi.org/10.1080/10641963.2017.1384481DOI Listing
August 2018

Prognostic Significance of Spot Urine Na/K for Longitudinal Changes in Blood Pressure and Renal Function: The Nagahama Study.

Am J Hypertens 2017 Sep;30(9):899-906

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1093/ajh/hpx075DOI Listing
September 2017

Self-reported quality of sleep is associated with physical strength among community-dwelling young-old adults.

Geriatr Gerontol Int 2017 Nov 6;17(11):1808-1813. Epub 2017 Jan 6.

Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1111/ggi.12965DOI Listing
November 2017

Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study.

Medicine (Baltimore) 2016 Apr;95(15):e3371

From the Department of Respiratory Medicine (SM, HM, II, YI, KM, MM); Center for Genomic Medicine, Kyoto University Graduate School of Medicine (YT, KS, TK, MT, CT, RY, FM); Department of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto (SK); Center for Preventive Medical Science, Chiba University, Chiba (AS); Department of Health Informatics, Kyoto University School of Public Health (TN); and Department of Respiratory Care and Sleep Control Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (KC).

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http://dx.doi.org/10.1097/MD.0000000000003371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839845PMC
April 2016

Are there different factors affecting walking speed and gait cycle variability between men and women in community-dwelling older adults?

Aging Clin Exp Res 2017 Apr 11;29(2):215-221. Epub 2016 Apr 11.

Human Health Science, Kyoto University Graduate School of Medicine, 53 Kawahara-cho, Shogoin, Sakyo, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s40520-016-0568-8DOI Listing
April 2017

Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study.

J Hypertens 2015 Dec;33(12):2407-13

aCenter for Genomic Medicine, Kyoto University Graduate School of Medicine bDepartment of Health Informatics, Kyoto University School of Public Health cDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine dDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto eCenter for Preventive Medical Science, Chiba University, Chiba, Japan.

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http://pdfs.journals.lww.com/jhypertension/2015/12000/Descri
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http://dx.doi.org/10.1097/HJH.0000000000000734DOI Listing
December 2015

Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels.

Nat Commun 2015 Jul 15;6:7754. Epub 2015 Jul 15.

1] Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi 53, Sakyo-ku, Kyoto 606-8507, Japan. [2] Statistical Genetics, Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi 53, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1038/ncomms8754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518310PMC
July 2015

Effect of PNPLA3 rs738409 variant (I148 M) on hepatic steatosis, necroinflammation, and fibrosis in Japanese patients with chronic hepatitis C.

J Gastroenterol 2015 Aug 26;50(8):887-93. Epub 2014 Nov 26.

Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/s00535-014-1018-zDOI Listing
August 2015

Central blood pressure relates more strongly to retinal arteriolar narrowing than brachial blood pressure: the Nagahama Study.

J Hypertens 2015 Feb;33(2):323-9

aDepartment of Ophthalmology and Visual Sciences bCenter for Genomic Medicine, Kyoto University Graduate School of Medicine cDepartment of Health Informatics dDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health eKyoto University Medical Research Support Center, Kyoto, Japan.

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http://dx.doi.org/10.1097/HJH.0000000000000391DOI Listing
February 2015

Association of serum-free fatty acid level with reduced reflection pressure wave magnitude and central blood pressure: the Nagahama study.

Hypertension 2014 Dec 8;64(6):1212-8. Epub 2014 Sep 8.

From the Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (Y.T., T.K., K.S., C.T., R.Y., F.M.); Departments of Health Informatics (Y.T., T.N.) and Medical Ethics and Medical Genetics (S.K.), Kyoto University School of Public Health, Kyoto, Japan; and Kyoto University Medical Research Support Center, Kyoto, Japan (A.S.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.114.
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04277DOI Listing
December 2014

The KSS 2011 reflects symptoms, physical activities, and radiographic grades in a Japanese population.

Clin Orthop Relat Res 2015 Jan;473(1):70-5

Department of Orthopaedic Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo, Kyoto, 606-8507, Japan.

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http://link.springer.com/10.1007/s11999-014-3650-6
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http://dx.doi.org/10.1007/s11999-014-3650-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390913PMC
January 2015

[Development of pharmacogenomics--guided tailored therapy for colorectal cancer].

Nihon Rinsho 2014 Jan;72(1):23-8

Department of Genomic Epidemiology, Graduate School of Medicine, Kyoto University.

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January 2014

Airflow limitation in smokers is associated with arterial stiffness: the Nagahama Study.

Atherosclerosis 2014 Jan 1;232(1):59-64. Epub 2013 Nov 1.

Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Shogoinkawaramachi, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.10.020DOI Listing
January 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Nature 2014 Feb 25;506(7488):376-81. Epub 2013 Dec 25.

1] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature12873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944098PMC
February 2014

Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy.

Invest Ophthalmol Vis Sci 2013 Sep 9;54(9):6068-73. Epub 2013 Sep 9.

Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1167/iovs.13-11605DOI Listing
September 2013

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.

Cancer Sci 2011 Jan 28;102(1):245-52. Epub 2010 Sep 28.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2010.01737.xDOI Listing
January 2011

Estimation of P-value of MAX test with double triangle diagram for 2 x 3 SNP case-control tables.

Genet Epidemiol 2010 Sep;34(6):543-51

Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1002/gepi.20510DOI Listing
September 2010

A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.

Nat Genet 2010 Sep 15;42(9):768-71. Epub 2010 Aug 15.

Laboratory of Molecular Medicine, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://www.nature.com/articles/ng.645
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http://dx.doi.org/10.1038/ng.645DOI Listing
September 2010