Takahiko Tokuda

Takahiko Tokuda

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Takahiko Tokuda

Publications by authors named "Takahiko Tokuda"

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Combined use of CSF NfL and CSF TDP-43 improves diagnostic performance in ALS.

Ann Clin Transl Neurol 2019 Nov 19. Epub 2019 Nov 19.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan.

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http://dx.doi.org/10.1002/acn3.50943DOI Listing
November 2019

Correlated levels of cerebrospinal fluid pathogenic proteins in drug-naïve Parkinson's disease.

BMC Neurol 2019 Jun 4;19(1):113. Epub 2019 Jun 4.

Department of Neurology, School of Medicine, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan.

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http://dx.doi.org/10.1186/s12883-019-1346-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549316PMC
June 2019

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases.

Parkinsonism Relat Disord 2019 04 20;61:82-87. Epub 2018 Nov 20.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan; Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.11.021DOI Listing
April 2019

Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders.

Brain Res 2019 Apr 19;1708:207-219. Epub 2018 Dec 19.

Department of Applied Biology, Kyoto Institute of Technology, Kyoto 606-8585, Japan; The Center for Advanced Insect Research, Kyoto Institute of Technology, Kyoto 606-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2018.12.028DOI Listing
April 2019

Regional dissociation between the cerebral blood flow and gray matter density alterations in idiopathic normal pressure hydrocephalous: results from SINPHONI-2 study.

Neuroradiology 2019 Jan 30;61(1):37-42. Epub 2018 Sep 30.

Department of Neurosurgery, Tama-Hokubu Medical Center, Health and Medical Treatment Corporation, Higashimurayamashi, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00234-018-2106-1DOI Listing
January 2019

Genetic screening of the genes interacting with Drosophila FIG4 identified a novel link between CMT-causing gene and long noncoding RNAs.

Exp Neurol 2018 12 28;310:1-13. Epub 2018 Aug 28.

Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan; The Center for Advanced Insect Research, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144886183037
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http://dx.doi.org/10.1016/j.expneurol.2018.08.009DOI Listing
December 2018

Amyotrophic Lateral Sclerosis Model.

Adv Exp Med Biol 2018;1076:79-95

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1007/978-981-13-0529-0_6DOI Listing
November 2018

Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.

Exp Cell Res 2018 10 6;371(2):311-321. Epub 2018 Aug 6.

Department of Applied Biology, Kyoto Institute of Technology, Hashikami-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan; The Center for Advanced Insect Research Promotion, Kyoto Institute of Technology, Hashikami-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.08.001DOI Listing
October 2018

Overexpression of , , improves motor neuron degeneration induced by knockdown of , .

Am J Neurodegener Dis 2018 5;7(1):11-31. Epub 2018 Feb 5.

Department of Applied Biology, Kyoto Institute of TechnologyMatsugasaki, Sakyo-ku, Kyoto, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840287PMC
February 2018

Mutations in the β-amyloid precursor protein in familial Alzheimer's disease increase Aβ oligomer production in cellular models.

Heliyon 2018 Jan 1;4(1):e00511. Epub 2018 Feb 1.

Department of Neurology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.1016/j.heliyon.2018.e00511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857613PMC
January 2018

Disability risk or unimproved symptoms following shunt surgery in patients with idiopathic normal-pressure hydrocephalus: post hoc analysis of SINPHONI-2.

J Neurosurg 2017 Jun 15;126(6):2002-2009. Epub 2016 Jul 15.

Normal Pressure Hydrocephalus Center, Department of Neurosurgery and Stroke Center, Rakuwakai Otowa Hospital, Kyoto.

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http://dx.doi.org/10.3171/2016.5.JNS16377DOI Listing
June 2017

Timed up and go test at tap test and shunt surgery in idiopathic normal pressure hydrocephalus.

Neurol Clin Pract 2017 Apr;7(2):98-108

Normal Pressure Hydrocephalus Center (SY, MI), Department of Neurosurgery, Rakuwakai Otowa Hospital, Kyoto; Department of Neurosurgery (MM, MN), Juntendo University Graduate School of Medicine, Tokyo; Department of Neurosurgery (MA), Atsuchi Neurosurgical Hospital, Kagoshima; Department of Neurosurgery (TK), Dohtoh Neurosurgical Hospital, Hokkaido; Department of Molecular Pathobiology of Brain Diseases (Neurology) (TT), Kyoto Prefectural University of Medicine; Department of Psychiatry (HK), Osaka University Graduate School of Medicine; and Department of Behavioral Neurology and Cognitive Neuroscience (EM), Tohoku University Graduate School of Medicine, Miyagi, Japan.

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http://dx.doi.org/10.1212/CPJ.0000000000000334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669413PMC
April 2017

Development of a Biochemical Diagnosis of Parkinson Disease by Detection of α-Synuclein Misfolded Aggregates in Cerebrospinal Fluid.

JAMA Neurol 2017 Feb;74(2):163-172

Mitchell Center for Alzheimer's Disease and Related Brain Disorders, The University of Texas School of Medicine at Houston.

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http://dx.doi.org/10.1001/jamaneurol.2016.4547DOI Listing
February 2017

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer's disease.

Sci Rep 2017 01 10;7:40263. Epub 2017 Jan 10.

Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, PO Box 5825, Doha, Qatar.

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http://dx.doi.org/10.1038/srep40263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223278PMC
January 2017

Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression.

Mov Disord 2016 10;31(10):1535-1542

Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, PO Box 5825, Doha, Qatar.

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http://dx.doi.org/10.1002/mds.26754DOI Listing
October 2016

Ventricular Temperatures in Idiopathic Normal Pressure Hydrocephalus (iNPH) Measured with DWI-based MR Thermometry.

Magn Reson Med Sci 2015 23;14(4):305-12. Epub 2015 Jun 23.

Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.2463/mrms.2014-0076DOI Listing
September 2016

Serum Levels of Coenzyme Q10 in Patients with Multiple System Atrophy.

PLoS One 2016 26;11(1):e0147574. Epub 2016 Jan 26.

Department of Neurology, Research Institute for Geriatrics, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147574PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727813PMC
July 2016

Knockdown of the Drosophila FIG4 induces deficient locomotive behavior, shortening of motor neuron, axonal targeting aberration, reduction of life span and defects in eye development.

Exp Neurol 2016 Mar 19;277:86-95. Epub 2015 Dec 19.

Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan; The Center for Advanced Insect Research, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2015.12.011DOI Listing
March 2016

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease.

Mol Neurodegener 2016 Jan 19;11. Epub 2016 Jan 19.

Neurological Disorders Center, Qatar Biomedical Research Institute, and College of Science and Engineering, Hamad Bin Khalifa University (HBKU), Education City, Qatar Foundation, P.O. Box 5825, Doha, Qatar.

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http://dx.doi.org/10.1186/s13024-016-0072-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717559PMC
January 2016

The domestic cat as a natural animal model of Alzheimer's disease.

Acta Neuropathol Commun 2015 Dec 10;3:78. Epub 2015 Dec 10.

Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1186/s40478-015-0258-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674944PMC
December 2015

[Emerging concept of the production and absorption of cerebrospinal fluid, and recent progress in the diagnosis and treatment of iNPH].

Authors:
Takahiko Tokuda

Rinsho Shinkeigaku 2014 ;54(12):1193-6

Department of Molecular Pathobiology of Brain Diseases (Neurology), Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.54.1193DOI Listing
October 2015

[New findings and concepts on production and absorption of cerebrospinal fluid: reconsiderations and revisions of an unquestioningly accepted dogma of 100 years].

Brain Nerve 2015 May;67(5):617-26

Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.11477/mf.1416200190DOI Listing
May 2015

[Differential diagnosis of corticobasal syndrome (CBS) and its biomarkers].

Authors:
Takahiko Tokuda

Rinsho Shinkeigaku 2013 ;53(11):1033-5

Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.53.1033DOI Listing
April 2015

Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils.

Neurobiol Dis 2015 Jan 22;73:244-53. Epub 2014 Oct 22.

Department of Basic Geriatrics, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto 602-8566, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2014.10.011DOI Listing
January 2015

Differential expression of alpha-synuclein in hippocampal neurons.

PLoS One 2014 25;9(2):e89327. Epub 2014 Feb 25.

Department of Basic Geriatrics, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089327PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3934906PMC
December 2014

Safety and tolerability of immune globulin intravenous (human), 10% solution in Japanese subjects with mild to moderate Alzheimer's disease.

Psychogeriatrics 2014 Sep 3;14(3):165-74. Epub 2014 Sep 3.

Department of Psychiatry, Juntendo University, Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/psyg.12055DOI Listing
September 2014

Genetic link between Cabeza, a Drosophila homologue of Fused in Sarcoma (FUS), and the EGFR signaling pathway.

Exp Cell Res 2014 Aug 11;326(1):36-45. Epub 2014 Jun 11.

Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan; Insect Biomedical Research Center, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.06.004DOI Listing
August 2014

Identification of ter94, Drosophila VCP, as a strong modulator of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.

Hum Mol Genet 2014 Jul 4;23(13):3467-80. Epub 2014 Feb 4.

Department of Applied Biology and Insect Biomedical Research Center, Kyoto Institute of Technology, Hashikami-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.

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http://dx.doi.org/10.1093/hmg/ddu055DOI Listing
July 2014

Increased α-synuclein levels in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.

J Neurol 2014 Jun 16;261(6):1203-9. Epub 2014 Apr 16.

Department of Neurology, Research Institute for Geriatrics, Kyoto Prefectural University of Medicine, Kyoto, 602-0841, Japan,

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http://dx.doi.org/10.1007/s00415-014-7334-7DOI Listing
June 2014

Contrasting echogenicity in flexor digitorum profundus-flexor carpi ulnaris: a diagnostic ultrasound pattern in sporadic inclusion body myositis.

Muscle Nerve 2014 May;49(5):745-8

Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, 602-0841, Japan.

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http://dx.doi.org/10.1002/mus.24056DOI Listing
May 2014

[Aiming to develop biochemical biomarkers for Parkinson's disease and related disorders].

Authors:
Takahiko Tokuda

Rinsho Shinkeigaku 2012 ;52(11):1332-4

Department of Molecular Pathobiology of Brain Diseases (Neurology), Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.52.1332DOI Listing
April 2014

Guidelines for management of idiopathic normal pressure hydrocephalus: second edition.

Neurol Med Chir (Tokyo) 2012 ;52(11):775-809

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Miyagi.

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http://dx.doi.org/10.2176/nmc.52.775DOI Listing
November 2013

Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples.

Neurosci Lett 2013 Sep 27;551:17-22. Epub 2013 Jun 27.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S030439401300576
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http://dx.doi.org/10.1016/j.neulet.2013.06.029DOI Listing
September 2013

p62/SQSTM1-dependent autophagy of Lewy body-like α-synuclein inclusions.

PLoS One 2012 31;7(12):e52868. Epub 2012 Dec 31.

Department of Basic Geriatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamikyo-ku, Kyoto, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052868PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534125PMC
June 2013

[Biomarkers for the differential diagnosis of corticobasal syndrome].

Authors:
Takahiko Tokuda

Brain Nerve 2013 Jan;65(1):55-64

Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Japan.

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January 2013

Biomarkers for the diagnosis and management of Parkinson's disease.

Expert Opin Med Diagn 2013 Jan 4;7(1):71-83. Epub 2012 Nov 4.

Tokyo Metropolitan Institute of Medical Science, Division of Sensory and Motor Systems, Tokyo 156-0057, Japan.

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http://dx.doi.org/10.1517/17530059.2013.733694DOI Listing
January 2013

[The cutting-edge of medicine; development of diagnostic biomarkers for neurodegenerative diseases].

Nihon Naika Gakkai Zasshi 2012 Nov;101(11):3247-55

Department of Neurology, Kyoto Prefectural University of Medicine, Japan.

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http://dx.doi.org/10.2169/naika.101.3247DOI Listing
November 2012

Utilization of a multiple antigenic peptide as a calibration standard in the BAN50 single antibody sandwich ELISA for Aβ oligomers.

Biochem Biophys Res Commun 2012 Jun 3;422(3):375-80. Epub 2012 May 3.

Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2012.04.146DOI Listing
June 2012

Cerebrospinal fluid proteomic patterns discriminate Parkinson's disease and multiple system atrophy.

Mov Disord 2012 Jun 1;27(7):851-7. Epub 2012 Jun 1.

Department of Neurology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1002/mds.24994DOI Listing
June 2012

[Biomarkers for amyotrophic lateral sclerosis].

Authors:
Takahiko Tokuda

Brain Nerve 2012 May;64(5):515-23

Department of Molecular Pathobiology of Brain Diseases, Kyoto Prefectural University of Medicine, Japan.

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May 2012

[Epileptic seizures in dementing diseases].

Nihon Rinsho 2011 Dec;69 Suppl 10 Pt 2:535-9

Department of Molecular Pathobiology of Brain Diseases (Department of Neurology), Kyoto Prefectural University of Medicine.

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December 2011

Flow velocity of the superior sagittal sinus is reduced in patients with idiopathic normal pressure hydrocephalus.

J Neuroimaging 2011 Oct 20;21(4):365-9. Epub 2011 Apr 20.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1111/j.1552-6569.2011.00592.xDOI Listing
October 2011

[Dementia: progress in diagnosis and treatment; Topics; V. Recent topics; 1. Biomarkers for Alzheimer's disease and other dementia].

Authors:
Takahiko Tokuda

Nihon Naika Gakkai Zasshi 2011 Aug;100(8):2177-86

Department of Molecular Pathobiology of Brain Diseases (Department of Neurology), Kyoto Prefectural University of Medicine, Japan.

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http://dx.doi.org/10.2169/naika.100.2177DOI Listing
August 2011

Usefulness of serum S100B as a marker for the acute phase of aquaporin-4 autoimmune syndrome.

Neurosci Lett 2011 Apr 1;494(1):86-8. Epub 2011 Mar 1.

Department of Neurology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.1016/j.neulet.2011.02.063DOI Listing
April 2011

Self-remitting and reversible parkinsonism associated with neuro-Sweet disease.

Intern Med 2010 15;49(12):1201-4. Epub 2010 Jun 15.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.2169/internalmedicine.49.3155DOI Listing
March 2011

[A rare complication of dysarthria in a patient with inclusion body myositis: a case report].

Rinsho Shinkeigaku 2010 Oct;50(10):695-9

Department of Neurology, Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.50.695DOI Listing
October 2010

Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.

Amyloid 2009 ;16(2):99-102

Department of Molecular Neurology and Gerontology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.1080/13506120902879335DOI Listing
September 2010

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients.

FASEB J 2010 Aug 25;24(8):2716-26. Epub 2010 Mar 25.

Pharmacology Research Division, Takeda Pharmaceutical Company, Osaka, Japan.

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http://dx.doi.org/10.1096/fj.09-150359DOI Listing
August 2010

Extracellular neurosin degrades α-synuclein in cultured cells.

Neurosci Res 2010 Aug 18;67(4):341-6. Epub 2010 Apr 18.

Department of Neurology, Research Institute for Neurological Diseases and Geriatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1016/j.neures.2010.04.008DOI Listing
August 2010

Differential levels of alpha-synuclein, beta-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease.

J Neurol Neurosurg Psychiatry 2010 Jun;81(6):608-10

Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Asahimachi 1-757, Chuo-ku, Niigata 951-8585, Japan.

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http://dx.doi.org/10.1136/jnnp.2009.197483DOI Listing
June 2010

Predictive markers of blood cytokine and chemokine in recurrent brain infarction.

J Interferon Cytokine Res 2009 Nov;29(11):729-34

Department of Neurology, Kyoto Prefectural University of Medicine, 465 Kawaramachi-hirokoji, Kamigyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1089/jir.2009.0012DOI Listing
November 2009

Evaluation of autonomic malfunction in HTLV-1 associated myelopathy (HAM).

Auton Neurosci 2009 Oct 23;150(1-2):131-5. Epub 2009 Jun 23.

Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kawaramachi-hirokoji, Kamigyo-ku,Kyoto, Japan.

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http://dx.doi.org/10.1016/j.autneu.2009.05.252DOI Listing
October 2009

[CSF normocytosis in meningitis due to primary infection of human immunodeficiency virus].

Rinsho Shinkeigaku 2009 Feb-Mar;49(2-3):100-3

Department of Neurology, Kyoto Prefectural University of Medicine.

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http://dx.doi.org/10.5692/clinicalneurol.49.100DOI Listing
May 2009

Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis.

Acta Neuropathol 2009 Jan 7;117(1):55-62. Epub 2008 Nov 7.

Department of Neurology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto, 602-0841, Japan.

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http://dx.doi.org/10.1007/s00401-008-0456-1DOI Listing
January 2009

CSF alpha-synuclein levels in dementia with Lewy bodies and Alzheimer's disease.

Brain Res 2009 Jan 28;1251:1-6. Epub 2008 Nov 28.

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1016/j.brainres.2008.11.055DOI Listing
January 2009

Retrograde jugular flow associated with idiopathic normal pressure hydrocephalus.

Ann Neurol 2008 Aug;64(2):217-21

Department of Neurology and Gerontology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Japan.

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http://dx.doi.org/10.1002/ana.21410DOI Listing
August 2008

Evaluation of autonomic malfunction in idiopathic normal pressure hydrocephalus.

Clin Auton Res 2008 Aug 23;18(4):213-20. Epub 2008 Jul 23.

Dept. of Neurology and Gerontology, Kyoto Prefectural University of Medicine, 465 Kawaramachi-hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

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http://dx.doi.org/10.1007/s10286-008-0482-zDOI Listing
August 2008

Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro.

Neurosci Lett 2008 May 4;436(1):52-6. Epub 2008 Mar 4.

Department of Neurology, Research Institute for Geriatrics, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400800257
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http://dx.doi.org/10.1016/j.neulet.2008.02.057DOI Listing
May 2008

An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid.

Brain Res 2007 Sep 20;1170:103-11. Epub 2007 Jul 20.

Biomedical Sciences Unit, Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930701653
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http://dx.doi.org/10.1016/j.brainres.2007.07.027DOI Listing
September 2007

Severe amyloid deposition in mammary glands of familial amyloid polyneuropathy patients.

Amyloid 2007 Sep;14(3):249-53

Department of Internal Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan.

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http://www.tandfonline.com/doi/full/10.1080/1350612070146122
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http://dx.doi.org/10.1080/13506120701461228DOI Listing
September 2007

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease.

Biochem Biophys Res Commun 2006 Oct 14;349(1):162-6. Epub 2006 Aug 14.

Department of Neurology, Kyoto Prefectural University of Medicine, Kyoto 602-0841, Japan, and Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbrc.2006.08.024DOI Listing
October 2006

A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.

Amyloid 2006 Mar;13(1):37-41

Department of Neurology, Neurological Institute, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.

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March 2006

Tacrolimus in refractory patients with myasthenia gravis: coadministration and tapering of oral prednisolone.

J Clin Neurosci 2006 Jan 22;13(1):39-44. Epub 2005 Nov 22.

The Third Department of Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.

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January 2006

Biochemical characteristics of variant transthyretins causing hereditary leptomeningeal amyloidosis.

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Third Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.

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December 2005

Unexpectedly high incidence of visceral AA-amyloidosis in slaughtered cattle in Japan.

Amyloid 2005 Jun;12(2):103-8

Third Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.

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June 2005

A Japanese patient with familial Mediterranean fever associated with compound heterozygosity for pyrin variant E148Q/M694I.

Intern Med 2005 Mar;44(3):261-5

Third Department of Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621.

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http://dx.doi.org/10.2169/internalmedicine.44.261DOI Listing
March 2005

MRI analysis on a patient with the V30M mutation is characteristic of leptomeningeal amyloid.

Amyloid 2004 Dec;11(4):265-7

Third Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.

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December 2004

Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo.

Amyloid 2004 Jun;11(2):113-20

Department of Biochemistry, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Nakakoma, Yamanashi 409-3898, Japan.

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June 2004