Publications by authors named "Tajie H Harris"

35Publications

Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling.

PLoS Pathog 2020 Oct 27;16(10):e1009027. Epub 2020 Oct 27.

Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1009027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647122PMC
October 2020

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.

Nat Commun 2020 07 23;11(1):3687. Epub 2020 Jul 23.

Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1038/s41467-020-17491-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378823PMC
July 2020

Long-'Trm' protection of the CNS.

Nat Immunol 2020 08;21(8):825-826

Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA, USA.

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http://dx.doi.org/10.1038/s41590-020-0716-3DOI Listing
August 2020

ICOS-deficient and ICOS YF mutant mice fail to control Toxoplasma gondii infection of the brain.

PLoS One 2020 24;15(1):e0228251. Epub 2020 Jan 24.

Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0228251PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980566PMC
April 2020

The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation.

J Exp Med 2019 06 11;216(6):1268-1279. Epub 2019 Apr 11.

Baker Institute for Animal Health and Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY

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http://dx.doi.org/10.1084/jem.20180131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547860PMC
June 2019

IL-10 and ICOS Differentially Regulate T Cell Responses in the Brain during Chronic Infection.

J Immunol 2019 03 4;202(6):1755-1766. Epub 2019 Feb 4.

Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, VA 22908

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http://dx.doi.org/10.4049/jimmunol.1801229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401250PMC
March 2019

Revisiting the Mechanisms of CNS Immune Privilege.

Trends Immunol 2015 Oct;36(10):569-577

Center for Brain Immunology and Glia, Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2015.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593064PMC
October 2015

Structural and functional features of central nervous system lymphatic vessels.

Nature 2015 Jul 1;523(7560):337-41. Epub 2015 Jun 1.

1] Center for Brain Immunology and Glia, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA [2] Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA [3] Medical Scientist Training Program, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1038/nature14432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506234PMC
July 2015

Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli.

Immunity 2015 Apr;42(4):679-91

Center for Brain Immunology and Glia, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA; Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA; Graduate Program in Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA; Medical Scientist Training Program, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA. Electronic address:

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http://www.cell.com/immunity/pdf/S1074-7613(15)00127-2.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S107476131500127
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http://dx.doi.org/10.1016/j.immuni.2015.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407145PMC
April 2015

Characteristics and critical function of CD8+ T cells in the Toxoplasma-infected brain.

Semin Immunopathol 2015 May 22;37(3):261-70. Epub 2015 Apr 22.

Division of Biomedical Sciences, University of California, Riverside, CA, 92521, USA.

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http://dx.doi.org/10.1007/s00281-015-0487-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313077PMC
May 2015

Heterogeneous CD8+ T cell migration in the lymph node in the absence of inflammation revealed by quantitative migration analysis.

PLoS Comput Biol 2015 Feb 18;11(2):e1004058. Epub 2015 Feb 18.

Department of Physics and Astronomy, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Philadelphia, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334969PMC
February 2015

Toxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria.

Infect Immun 2014 Mar 6;82(3):1343-53. Epub 2014 Jan 6.

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1128/IAI.01259-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957979PMC
March 2014

Regulation of immunopathogenesis during Plasmodium and Toxoplasma infections: more parallels than distinctions?

Trends Parasitol 2013 Dec 1;29(12):593-602. Epub 2013 Nov 1.

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2013.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883126PMC
December 2013

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells.

Nature 2012 Jun;486(7404):545-8

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 380 South University Avenue, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature11098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387349PMC
June 2012

A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8⁺ T-cell accumulation in the skin.

J Invest Dermatol 2012 Jul 2;132(7):1869-76. Epub 2012 Feb 2.

Division of Dermatology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/jid.2011.463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343174PMC
July 2012

Toll-like receptor 4 contributes to poor outcome after intracerebral hemorrhage.

Ann Neurol 2011 Oct;70(4):646-56

Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/ana.22528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671585PMC
October 2011

Analysis of behavior and trafficking of dendritic cells within the brain during toxoplasmic encephalitis.

PLoS Pathog 2011 Sep 15;7(9):e1002246. Epub 2011 Sep 15.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174247PMC
September 2011

Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage.

Acta Neurochir Suppl 2011 ;111:173-8

Department of Neurology, University of Pennsylvania Medical Center, 3 W Gates, 3400 Spruce Street, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-3-7091-0693-8_29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702167PMC
September 2011

CXCL10 is required to maintain T-cell populations and to control parasite replication during chronic ocular toxoplasmosis.

Invest Ophthalmol Vis Sci 2011 Jan 21;52(1):389-98. Epub 2011 Jan 21.

Department of Infection and Host Defense, Graduate School of Medicine, Chiba University, Chiba, Japan.

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http://dx.doi.org/10.1167/iovs.10-5819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053287PMC
January 2011

Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.

J Immunol 2010 Aug 30;185(3):1502-12. Epub 2010 Jun 30.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Room H310F Hill Pavilion, 380 South University Avenue, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.0903450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039871PMC
August 2010

NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS.

J Neuroimmunol 2010 May 13;222(1-2):19-28. Epub 2010 Feb 13.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 380 S University Ave, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.jneuroim.2009.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860689PMC
May 2010

Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii.

PLoS Pathog 2009 Jul 3;5(7):e1000505. Epub 2009 Jul 3.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1371/journal.ppat.1000505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700268PMC
July 2009

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10.

Nat Immunol 2007 Dec 11;8(12):1363-71. Epub 2007 Nov 11.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni1537DOI Listing
December 2007

CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes.

Infect Immun 2007 May 5;75(5):2366-73. Epub 2007 Mar 5.

Department of Medical Microbiology and Immunology, University of Wisconsin-Madison School of Medicine and Public Health, Wisconsin 53706, USA.

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http://dx.doi.org/10.1128/IAI.01649-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865757PMC
May 2007

Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA.

Infect Immun 2006 Aug;74(8):4530-7

Department of Medical Microbiology and Immunology, University of Wisconsin Medical School of Medicine and Public Health, 1300 University Avenue, Madison, Wisconsin 53706-1532, USA.

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http://dx.doi.org/10.1128/IAI.01938-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539588PMC
August 2006