Taishin Akiyama

Taishin Akiyama

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Taishin Akiyama

Taishin Akiyama

Publications by authors named "Taishin Akiyama"

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TRAF6 maintains mammary stem cells and promotes pregnancy-induced mammary epithelial cell expansion.

Commun Biol 2019 6;2:292. Epub 2019 Aug 6.

1Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639 Japan.

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http://dx.doi.org/10.1038/s42003-019-0547-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684589PMC
August 2019

Long-term hindlimb unloading causes a preferential reduction of medullary thymic epithelial cells expressing autoimmune regulator (Aire).

Biochem Biophys Res Commun 2018 06;501(3):745-750

Center for Integrative Medical Science, RIKEN, Yokohama 230-0045, Japan; Mouse Epigenetics Project, ISS/Kibo experiment, Japan Aerospace Exploration Agency (JAXA), Tsukuba, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183111
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http://dx.doi.org/10.1016/j.bbrc.2018.05.060DOI Listing
June 2018

Chemical Synthesis of d-glycero-d-manno-Heptose 1,7-Bisphosphate and Evaluation of Its Ability to Modulate NF-κB Activation.

Org Lett 2017 06 25;19(12):3079-3082. Epub 2017 May 25.

Graduate School of Science and Technology, Keio University 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, Kanagawa 223-8522, Japan.

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http://dx.doi.org/10.1021/acs.orglett.7b01158DOI Listing
June 2017

Regional regulation of Filiform tongue papillae development by Ikkα/Irf6.

Dev Dyn 2016 09 13;245(9):937-46. Epub 2016 Jul 13.

Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1002/dvdy.24427DOI Listing
September 2016

Visualization of RelB expression and activation at the single-cell level during dendritic cell maturation in Relb-Venus knock-in mice.

J Biochem 2015 Dec 26;158(6):485-95. Epub 2015 Jun 26.

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan;

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http://dx.doi.org/10.1093/jb/mvv064DOI Listing
December 2015

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.

J Exp Med 2015 Oct 12;212(11):1967-85. Epub 2015 Oct 12.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229 Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267

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http://jem.rupress.org/content/212/11/1967.full.pdf
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http://www.jem.org/lookup/doi/10.1084/jem.20141898
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http://dx.doi.org/10.1084/jem.20141898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612089PMC
October 2015

Identification of transcription factors activated in thymic epithelial cells during embryonic thymus development.

Methods Mol Biol 2014 ;1164:163-70

Division of Cellular and Molecular Biology, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo, 108-8639, Japan,

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http://link.springer.com/content/pdf/10.1007%2F978-1-4939-08
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http://link.springer.com/10.1007/978-1-4939-0805-9_13
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http://dx.doi.org/10.1007/978-1-4939-0805-9_13DOI Listing
January 2015

Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases.

Front Immunol 2013 26;4:249. Epub 2013 Aug 26.

Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo , Tokyo , Japan.

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http://dx.doi.org/10.3389/fimmu.2013.00249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752772PMC
August 2013

DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells.

BMC Immunol 2012 Nov 2;13:58. Epub 2012 Nov 2.

Laboratory of Cellular Biochemistry, Department of Animal Resource Sciences/Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1186/1471-2172-13-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546423PMC
November 2012

TNF receptor family signaling in the development and functions of medullary thymic epithelial cells.

Front Immunol 2012 4;3:278. Epub 2012 Sep 4.

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo Tokyo, Japan.

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http://dx.doi.org/10.3389/fimmu.2012.00278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432834PMC
September 2012

RANKL-RANK interaction in immune regulatory systems.

World J Orthop 2012 Sep;3(9):142-50

Taishin Akiyama, Miho Shinzawa, Nobuko Akiyama, Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.5312/wjo.v3.i9.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502610PMC
September 2012

Splenic extramedullary hemopoiesis caused by a dysfunctional mutation in the NF-κB-inducing kinase gene.

Biochem Biophys Res Commun 2011 Nov 7;414(4):773-8. Epub 2011 Oct 7.

Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.10.001DOI Listing
November 2011

[Regulation of central tolerance by RANKL signaling].

Clin Calcium 2011 Aug;21(8):1193-9

Institute of Medical Science, University of Tokyo, Japan.

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http://dx.doi.org/CliCa110811931199DOI Listing
August 2011

RANK signaling induces interferon-stimulated genes in the fetal thymic stroma.

Biochem Biophys Res Commun 2011 May 19;408(4):530-6. Epub 2011 Apr 19.

Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.04.049DOI Listing
May 2011

TRAF6 directs commitment to regulatory T cells in thymocytes.

Genes Cells 2011 Apr 15;16(4):437-47. Epub 2011 Mar 15.

Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2011.01500.xDOI Listing
April 2011

TRAF6 negatively regulates the Jak1-Erk pathway in interleukin-2 signaling.

Genes Cells 2011 Feb 13;16(2):179-89. Epub 2010 Dec 13.

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2010.01474.xDOI Listing
February 2011

Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.

J Biol Chem 2010 Jul 11;285(29):21951-60. Epub 2010 May 11.

Division of Host-Parasite Interaction, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1074/jbc.M109.087783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903353PMC
July 2010

Independent stabilizations of polysomal Drg1/Dfrp1 complex and non-polysomal Drg2/Dfrp2 complex in mammalian cells.

Biochem Biophys Res Commun 2009 Dec 9;390(3):552-6. Epub 2009 Oct 9.

Department of Life Science and Medical Bio-Science, Waseda University, Tokyo 162-8480, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X090196
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http://dx.doi.org/10.1016/j.bbrc.2009.10.003DOI Listing
December 2009

TRAF6 specifically contributes to FcepsilonRI-mediated cytokine production but not mast cell degranulation.

J Biol Chem 2008 Nov 4;283(46):32110-8. Epub 2008 Sep 4.

Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia B3K 6R8, Canada.

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http://dx.doi.org/10.1074/jbc.M802610200DOI Listing
November 2008

Characteristics and biological functions of TRAF6.

Adv Exp Med Biol 2007 ;597:72-9

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1007/978-0-387-70630-6_6DOI Listing
August 2007

NF-kappaB activation in development and progression of cancer.

Cancer Sci 2007 Mar;98(3):268-74

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2007.00389.xDOI Listing
March 2007

IL-18 produced by thymic epithelial cells induces development of dendritic cells with CD11b in the fetal thymus.

Int Immunol 2006 Aug 13;18(8):1253-63. Epub 2006 Jun 13.

Institute of Molecular and Cellular Biosciences, University of Tokyo, 1-1-1 Yayoi, Tokyo 113-0032, Japan.

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http://dx.doi.org/10.1093/intimm/dxl058DOI Listing
August 2006

Dependence of self-tolerance on TRAF6-directed development of thymic stroma.

Science 2005 Apr 10;308(5719):248-51. Epub 2005 Feb 10.

Division of Cellular and Molecular Biology, Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1126/science.1105677DOI Listing
April 2005

TIFAB inhibits TIFA, TRAF-interacting protein with a forkhead-associated domain.

Biochem Biophys Res Commun 2004 Apr;317(1):230-4

Division of Cellular and Molecular Biology, Department of Cancer Biology, Institute of Medical Science, University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.030DOI Listing
April 2004

Cloning and characterization of Xenopus laevis drg2, a member of the developmentally regulated GTP-binding protein subfamily.

Gene 2003 Dec;322:105-12

Department of Cancer Biology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Tokyo 108-8639, Minato, Japan.

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http://dx.doi.org/10.1016/j.gene.2003.08.016DOI Listing
December 2003

Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling.

J Biol Chem 2003 Apr 3;278(14):12144-50. Epub 2003 Feb 3.

Division of Cellular and Molecular Biology, Department of Cancer Biology, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1074/jbc.M300720200DOI Listing
April 2003

Elimination of the vertebrate Escherichia coli Ras-like protein homologue leads to cell cycle arrest at G1 phase and apoptosis.

Oncogene 2003 Mar;22(9):1340-8

Division of Cellular and Molecular Biology, Department of Cancer Biology, The Institute of Medical Science, The University of Tokyo, Japan.

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http://dx.doi.org/10.1038/sj.onc.1206287DOI Listing
March 2003