Publications by authors named "Taina Pihlajaniemi"

100Publications

Lack of collagen XVIII leads to lipodystrophy and perturbs hepatic glucose and lipid homeostasis.

J Physiol 2020 Aug 15;598(16):3373-3393. Epub 2020 Jun 15.

Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1113/JP279559DOI Listing
August 2020

Exploring the roles of MACIT and multiplexin collagens in stem cells and cancer.

Semin Cancer Biol 2020 05 31;62:134-148. Epub 2019 Aug 31.

Center for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 7C, FI-90230, Oulu, Finland.

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http://dx.doi.org/10.1016/j.semcancer.2019.08.033DOI Listing
May 2020

Toward understanding scarless skin wound healing and pathological scarring.

F1000Res 2019 5;8. Epub 2019 Jun 5.

Oulu Center for Cell-Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.12688/f1000research.18293.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556993PMC
June 2020

Collagen XIII-derived ectodomain regulates bone angiogenesis and intracortical remodeling.

Matrix Biol 2019 10 17;83:6-25. Epub 2019 Jun 17.

Oulu Center for Cell-Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, P.O. Box 5400, FIN-90014, University of Oulu, Oulu, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2019.06.005DOI Listing
October 2019

Collagen XVIII Deposition in the Basement Membrane Zone beneath the Newly Forming Epidermis during Wound Healing in Mice.

Acta Med Okayama 2019 Apr;73(2):135-146

Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama 700-8558, Japan.

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http://dx.doi.org/10.18926/AMO/56649DOI Listing
April 2019

Collagen XIII and Other ECM Components in the Assembly and Disease of the Neuromuscular Junction.

Anat Rec (Hoboken) 2020 06 1;303(6):1653-1663. Epub 2019 Mar 1.

Oulu Center for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1002/ar.24092DOI Listing
June 2020

Correct expression and localization of collagen XIII are crucial for the normal formation and function of the neuromuscular system.

Eur J Neurosci 2019 06 8;49(11):1491-1511. Epub 2019 Feb 8.

Faculty of Biochemistry and Molecular Medicine, Center for Cell-Matrix Research, Biocenter Oulu, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1111/ejn.14346DOI Listing
June 2019

Collagen XIII Is Required for Neuromuscular Synapse Regeneration and Functional Recovery after Peripheral Nerve Injury.

J Neurosci 2018 04 6;38(17):4243-4258. Epub 2018 Apr 6.

Center for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014 Oulu, Finland,

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http://dx.doi.org/10.1523/JNEUROSCI.3119-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596032PMC
April 2018

Expression of a specific extracellular matrix signature is a favorable prognostic factor in acute myeloid leukemia.

Leuk Res Rep 2018 13;9:9-13. Epub 2017 Dec 13.

Centre of Excellence in Cell-Extracellular Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.lrr.2017.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735295PMC
December 2017

Understanding the extracellular matrix in acute myeloid leukemia.

Haematologica 2017 11;102(11):1807-1809

Centre of Excellence in Cell-Extracellular Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2017.174847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664384PMC
November 2017

Vanin 1 (VNN1) levels predict poor outcome in acute myeloid leukemia.

Am J Hematol 2018 01 23;93(1):E4-E7. Epub 2017 Oct 23.

Centre of Excellence in Cell-Extracellular Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1002/ajh.24925DOI Listing
January 2018

Autoimmune antibodies to collagen XIII in myasthenia gravis patients.

Muscle Nerve 2018 03 30;57(3):506-510. Epub 2017 Nov 30.

Centre of Excellence in Cell-Extracellular Matrix Research, Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, FIN 90014, Oulu, Finland.

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http://dx.doi.org/10.1002/mus.25969DOI Listing
March 2018

An extracellular matrix signature in leukemia precursor cells and acute myeloid leukemia.

Haematologica 2017 07 14;102(7):e245-e248. Epub 2017 Apr 14.

Centre of Excellence in Cell-Extracellular Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland.

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http://dx.doi.org/10.3324/haematol.2017.167304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566047PMC
July 2017

Collagen XIII secures pre- and postsynaptic integrity of the neuromuscular synapse.

Hum Mol Genet 2017 06;26(11):2076-2090

Center for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, PO Box 5400, 90014 University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1093/hmg/ddx101DOI Listing
June 2017

Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma.

Am J Pathol 2017 May 17;187(5):1186-1197. Epub 2017 Mar 17.

Department of Dermatology, University of Turku and Turku University Hospital, Turku, Finland; MediCity Research Laboratory, University of Turku, Turku, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.01.006DOI Listing
May 2017

Lack of collagen XV is protective after ischemic stroke in mice.

Cell Death Dis 2017 01 12;8(1):e2541. Epub 2017 Jan 12.

Department of Neurobiology, A. I. Virtanen Institute for Molecular Sciences, Biocenter Kuopio, University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1038/cddis.2016.456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386367PMC
January 2017

Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.

J Med Chem 2017 01 9;60(2):814-820. Epub 2017 Jan 9.

Drug and Target Discovery, Department of Pharmacy and Pharmacology, University of Bath , Claverton Down, Bath, Somerset BA2 7AY, U. K.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01574DOI Listing
January 2017

Collagen XVIII in tissue homeostasis and dysregulation - Lessons learned from model organisms and human patients.

Matrix Biol 2017 01 13;57-58:55-75. Epub 2016 Oct 13.

Oulu Center for Cell-Matrix Research, Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.matbio.2016.10.002DOI Listing
January 2017

Editorial: Wound healing and fibrosis-two sides of the same coin.

Cell Tissue Res 2016 Sep;365(3):449-51

Biochemistry and Molecular Medicine, University of Oulo, Oulo, Finland.

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http://dx.doi.org/10.1007/s00441-016-2478-7DOI Listing
September 2016

Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors.

Neoplasia 2016 07;18(7):436-46

Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, FIN-90014, University of Oulu, Oulu, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954931PMC
July 2016

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.

Kidney Int 2016 06 14;89(6):1281-92. Epub 2016 Apr 14.

Department of Medicine, Renal Research Institute, New York Medical College, Valhalla, New York, USA; Department of Pharmacology, Renal Research Institute, New York Medical College, Valhalla, New York, USA; Department of Physiology, Renal Research Institute, New York Medical College, Valhalla, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868664PMC
June 2016

Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis.

Biogerontology 2016 08 28;17(4):749-61. Epub 2016 Apr 28.

Department of Ophthalmology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.

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http://dx.doi.org/10.1007/s10522-016-9647-7DOI Listing
August 2016

Membrane-associated collagens with interrupted triple-helices (MACITs): evolution from a bilaterian common ancestor and functional conservation in C. elegans.

BMC Evol Biol 2015 Dec 14;15:281. Epub 2015 Dec 14.

Centre of Excellence in Cell-Extracellular Matrix Research, Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Aapistie 5, Oulu, FIN 90014, Finland.

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http://dx.doi.org/10.1186/s12862-015-0554-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678570PMC
December 2015

Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences.

Redox Biol 2015 Dec 28;6:344-352. Epub 2015 Aug 28.

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565043PMC
December 2015

Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics.

Bioorg Med Chem 2015 Aug 2;23(15):4139-4149. Epub 2015 Jul 2.

Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, PO Box 5400, FIN-90014 Oulu, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2015.06.063DOI Listing
August 2015

Endostatin induces proliferation of oral carcinoma cells but its effect on invasion is modified by the tumor microenvironment.

Exp Cell Res 2015 Aug 22;336(1):130-40. Epub 2015 Jun 22.

Research Group of Cancer and Translational Medicine, Faculty of Medicine, University of Oulu, Finland; Medical Research Center, Oulu University Hospital, Oulu, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2015.06.012DOI Listing
August 2015

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma.

J Invest Dermatol 2015 Jul 19;135(7):1882-1892. Epub 2015 Mar 19.

Department of Dermatology, University of Turku and Turku University Hospital, Turku, Finland; MediCity Research Laboratory, University of Turku, Turku, Finland. Electronic address:

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http://dx.doi.org/10.1038/jid.2015.104DOI Listing
July 2015

Neural ECM and synaptogenesis.

Prog Brain Res 2014 ;214:29-51

Department of Physiology, School of Medicine, Keio University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/B978-0-444-63486-3.00002-5DOI Listing
August 2015

[Many dimensions of extracellular matrix research].

Duodecim 2013 ;129(21):2262-72

Oulun yliopisto, biolääketieteen laitos.

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January 2014

Collagen XVIII short isoform is critical for retinal vascularization, and overexpression of the Tsp-1 domain affects eye growth and cataract formation.

Invest Ophthalmol Vis Sci 2013 Nov 13;54(12):7450-62. Epub 2013 Nov 13.

Oulu Center for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1167/iovs.13-13039DOI Listing
November 2013

para-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitors.

ChemMedChem 2013 Dec 15;8(12):1978-85. Epub 2013 Oct 15.

Department of Biochemistry and Biocenter Oulu, 90014 University of Oulu, PO Box 3000 Oulu (Finland).

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http://dx.doi.org/10.1002/cmdc.201300337DOI Listing
December 2013

Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.

J Med Chem 2013 Oct 11;56(20):7880-9. Epub 2013 Oct 11.

Department of Biochemistry and Biocenter Oulu, University of Oulu , Oulu 90570, Finland.

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http://dx.doi.org/10.1021/jm401463yDOI Listing
October 2013

Expression of VEGF and collagen XVIII in meningiomas: correlations with histopathological and MRI characteristics.

Acta Neurochir (Wien) 2013 Jun 20;155(6):989-96; discussion 996. Epub 2013 Apr 20.

Department of Neurosurgery, Institute of Clinical Medicine, University of Oulu, Oulu, P.O. Box 21, 90029 OYS, Finland.

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http://dx.doi.org/10.1007/s00701-013-1699-8DOI Listing
June 2013

Target-derived matricryptins organize cerebellar synapse formation through α3β1 integrins.

Cell Rep 2012 Aug 9;2(2):223-30. Epub 2012 Aug 9.

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, 23298, USA.

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http://dx.doi.org/10.1016/j.celrep.2012.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432753PMC
August 2012

Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.

Cancer Res 2012 Jul 16;72(14):3512-21. Epub 2012 May 16.

Molecular/Cancer Biology Program, Institute for Molecular Medicine Finland and Helsinki University Central Hospital, Research Programs Unit, Biomedicum Helsinki, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1070DOI Listing
July 2012

Collagen XIII: a type II transmembrane protein with relevance to musculoskeletal tissues, microvessels and inflammation.

Int J Biochem Cell Biol 2012 May 8;44(5):714-7. Epub 2012 Feb 8.

Center for Cell-Matrix Research and Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, PO Box 5000, 90014 University of Oulu, Finland.

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http://dx.doi.org/10.1016/j.biocel.2012.01.024DOI Listing
May 2012

Lack of collagen XVIII long isoforms affects kidney podocytes, whereas the short form is needed in the proximal tubular basement membrane.

J Biol Chem 2011 Mar 30;286(10):7755-64. Epub 2010 Dec 30.

Department of Medical Biochemistry and Molecular Biology, Oulu Center for Cell Matrix Research, Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M110.166132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048663PMC
March 2011

The multiple functions of collagen XVIII in development and disease.

Matrix Biol 2011 Mar 14;30(2):83-92. Epub 2010 Dec 14.

Oulu Center for Cell-Matrix Research, Biocenter and Department of Medical Biochemistry and Molecular Biology, Institute of Biomedicine, University of Oulu, Finland

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http://dx.doi.org/10.1016/j.matbio.2010.11.001DOI Listing
March 2011

Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction.

J Neurosci 2010 Oct;30(43):14490-501

Oulu Center for Cell-Matrix Research, Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, University of Oulu, and Department of Clinical Neurophysiology, Oulu University Hospital, FIN-90221 Oulu, Finland.

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http://dx.doi.org/10.1523/JNEUROSCI.2644-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6634795PMC
October 2010

Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis.

Am J Pathol 2010 Nov 23;177(5):2527-40. Epub 2010 Sep 23.

Department of Genetics, Boys Town National Research Hospital, and Department of Immunology, Creighton University, 555 North 30 St., Omaha, NE 68131, USA.

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http://dx.doi.org/10.2353/ajpath.2010.100017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966809PMC
November 2010

Recombinant human collagen XV regulates cell adhesion and migration.

J Biol Chem 2010 Feb 29;285(8):5258-65. Epub 2009 Dec 29.

Oulu Centre for Cell-Matrix Research, Department of Medical Biochemistry and Molecular Biology, Institute of Biomedicine, University of Oulu, 90014 Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M109.033787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820754PMC
February 2010

Endostatin affects osteoblast behavior in vitro, but collagen XVIII/endostatin is not essential for skeletal development in vivo.

Calcif Tissue Int 2009 Nov 10;85(5):412-20. Epub 2009 Sep 10.

Department of Anatomy and Cell Biology, Institute of Biomedicine, University of Oulu, Oulu, Finland.

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http://link.springer.com/10.1007/s00223-009-9287-x
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http://dx.doi.org/10.1007/s00223-009-9287-xDOI Listing
November 2009

Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome.

Mol Vis 2009 23;15:801-9. Epub 2009 Apr 23.

Centro de Estudos do Genoma Humano, Departamento de Genética e Biologia Evolutiva, Instituto de Biociências, Universidade de São Paulo, São Paulo, Brazil.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671584PMC
August 2009

Type XVIII collagen degradation products in acute lung injury.

Crit Care 2009 9;13(2):R52. Epub 2009 Apr 9.

Lung Injury and Fibrosis Treatment Program (LIFT), Department of Medical Sciences, The Medical School University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

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http://ccforum.biomedcentral.com/articles/10.1186/cc7779
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http://dx.doi.org/10.1186/cc7779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689499PMC
September 2009

Cardiac dysfunction in transgenic mouse fetuses overexpressing shortened type XIII collagen.

Cell Tissue Res 2008 Jul 15;333(1):61-9. Epub 2008 May 15.

Oulu Center to Cell-Matrix Research, Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, University of Oulu, P. O. Box 5000, 90014, Oulu, Finland.

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http://link.springer.com/10.1007/s00441-008-0617-5
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http://dx.doi.org/10.1007/s00441-008-0617-5DOI Listing
July 2008

Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing.

Matrix Biol 2008 Jul 1;27(6):535-46. Epub 2008 Apr 1.

Biocenter Oulu, Collagen Research Unit, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.matbio.2008.03.003DOI Listing
July 2008

Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice.

Cancer Res 2007 Dec;67(24):11528-35

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1458DOI Listing
December 2007

[Not Available].

Duodecim 2007 ;123(12):1371-3

Biocenter Oulu, Oulun yliopisto, Biokeskus Suomi.

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April 2008

The role of disulfide bonds and alpha-helical coiled-coils in the biosynthesis of type XIII collagen and other collagenous transmembrane proteins.

J Biol Chem 2007 May 7;282(20):14898-905. Epub 2007 Mar 7.

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, PO Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M609605200DOI Listing
May 2007

Basement membrane protein distribution in LYVE-1-immunoreactive lymphatic vessels of normal tissues and ovarian carcinomas.

Cell Tissue Res 2007 May 30;328(2):317-28. Epub 2007 Jan 30.

Institute of Biomedicine/Anatomy, University of Helsinki, Haartmaninkatu 8, FI-00014, Helsinki, Finland.

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http://dx.doi.org/10.1007/s00441-006-0366-2DOI Listing
May 2007

Modulation of the cellular cholesterol level affects shedding of the type XIII collagen ectodomain.

J Biol Chem 2006 Nov 1;281(44):33352-62. Epub 2006 Sep 1.

Collagen Research Unit, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M605896200DOI Listing
November 2006

Collagen XVIII/endostatin shows a ubiquitous distribution in human ocular tissues and endostatin-containing fragments accumulate in ocular fluid samples.

Graefes Arch Clin Exp Ophthalmol 2007 Jan 13;245(1):74-81. Epub 2006 Apr 13.

Department of Ophthalmology, Helsinki University Central Hospital, P.O. Box 220, 00029 Helsinki, HUS, Finland.

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http://dx.doi.org/10.1007/s00417-006-0281-yDOI Listing
January 2007

Collagen XVIII/endostatin is associated with the epithelial-mesenchymal transformation in the atrioventricular valves during cardiac development.

Dev Dyn 2006 Jan;235(1):132-42

Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

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http://dx.doi.org/10.1002/dvdy.20556DOI Listing
January 2006

Type XIII collagen expression is induced during malignant transformation in various epithelial and mesenchymal tumours.

J Pathol 2005 Nov;207(3):324-35

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, PO Box 5000, 90014 University of Oulu, Finland.

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http://dx.doi.org/10.1002/path.1836DOI Listing
November 2005

The shed ectodomain of type XIII collagen associates with the fibrillar fibronectin matrix and may interfere with its assembly in vitro.

Biochem J 2006 Jan;393(Pt 1):43-50

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, P.O. Box 5000, 90014 University of Oulu, Finland.

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http://dx.doi.org/10.1042/BJ20051073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383662PMC
January 2006

Type XIII collagen strongly affects bone formation in transgenic mice.

J Bone Miner Res 2005 Aug 21;20(8):1381-93. Epub 2005 Mar 21.

Collagen Research Unit, Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1359/JBMR.050319DOI Listing
August 2005

Abnormal maturation of the retinal vasculature in type XVIII collagen/endostatin deficient mice and changes in retinal glial cells due to lack of collagen types XV and XVIII.

FASEB J 2005 Sep 23;19(11):1564-6. Epub 2005 Jun 23.

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Oulu, Finland.

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http://www.fasebj.org/doi/10.1096/fj.04-3101fje
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http://dx.doi.org/10.1096/fj.04-3101fjeDOI Listing
September 2005

Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.

Exp Cell Res 2005 Jul;307(2):292-304

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, PO Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.yexcr.2005.03.021DOI Listing
July 2005

Endostatin overexpression specifically in the lens and skin leads to cataract and ultrastructural alterations in basement membranes.

Am J Pathol 2005 Jan;166(1):221-9

Department of Medical Biochemistry and Molecular Biology, Biocenter Oulu, University of Oulu, Aapistie 7, FI 90220, Oulu, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1602290PMC
http://dx.doi.org/10.1016/S0002-9440(10)62246-8DOI Listing
January 2005

Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.

Matrix Biol 2004 Jun;23(3):153-61

Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, P.O. Box 5281, 90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.matbio.2004.04.003DOI Listing
June 2004

Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line.

Hum Mol Genet 2004 Sep 14;13(18):2089-99. Epub 2004 Jul 14.

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, 90014 Oulu, Finland.

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http://dx.doi.org/10.1093/hmg/ddh213DOI Listing
September 2004

The shed ectodomain of type XIII collagen affects cell behaviour in a matrix-dependent manner.

Biochem J 2004 Jun;380(Pt 3):685-93

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, P.O. Box 5000, 90014 Oulu, Finland.

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http://dx.doi.org/10.1042/BJ20031974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224210PMC
June 2004

Double knockout mice reveal a lack of major functional compensation between collagens XV and XVIII.

Matrix Biol 2003 Sep;22(5):443-8

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, P.O. Box 5000, Oulu 90014, Finland.

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http://dx.doi.org/10.1016/s0945-053x(03)00074-xDOI Listing
September 2003

Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif.

Matrix Biol 2003 Sep;22(5):427-42

Collagen Research Unit, Biocenter Oulu, Department of Medical Biochemistry and Molecular Biology, University of Oulu, P.O. Box 5000, Oulu 90014, Finland.

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http://dx.doi.org/10.1016/s0945-053x(03)00073-8DOI Listing
September 2003

Lack of type XVIII collagen results in anterior ocular defects.

FASEB J 2003 Dec 2;17(15):2257-9. Epub 2003 Oct 2.

Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Finland.

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http://dx.doi.org/10.1096/fj.02-1001fjeDOI Listing
December 2003

Type XIII collagen and some other transmembrane collagens contain two separate coiled-coil motifs, which may function as independent oligomerization domains.

J Biol Chem 2003 Sep 27;278(39):37590-9. Epub 2003 Jun 27.

Collagen Research Unit, Biocenter, University of Oulu, P. O. Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M305974200DOI Listing
September 2003

Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13.

J Biol Chem 2003 Jun 10;278(25):22404-11. Epub 2003 Apr 10.

Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M210325200DOI Listing
June 2003

Patterning parameters associated with the branching of the ureteric bud regulated by epithelial-mesenchymal interactions.

Int J Dev Biol 2003 Feb;47(1):3-13

Biocenter Oulu and Department of Biochemistry, Faculties of Science and Medicine, University of Oulu, Finland.

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February 2003

Collagen XVIII, a basement membrane heparan sulfate proteoglycan, interacts with L-selectin and monocyte chemoattractant protein-1.

J Biol Chem 2003 Apr 28;278(15):13069-76. Epub 2003 Jan 28.

Laboratory of Molecular and Cellular Recognition, Osaka University Graduate School of Medicine, 2-2, Yamada-oka, Suita 565-0871, Japan.

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http://dx.doi.org/10.1074/jbc.M212244200DOI Listing
April 2003

Adhesion of soluble fibronectin, vitronectin, and collagen type IV to intraocular lens materials.

J Cataract Refract Surg 2003 Jan;29(1):146-52

SLP, Finnish Medical Care Ltd., Vaasa, Finland.

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http://dx.doi.org/10.1016/s0886-3350(02)01422-0DOI Listing
January 2003

Cloning of three variants of type XVIII collagen and their expression patterns during Xenopus laevis development.

Mech Dev 2002 Jun;114(1-2):109-13

Collagen Research Unit, Biocenter and Department of Medical Biochemistry, University of Oulu, P.O. Box 5000, Aapistie 7, 90014, Oulu, Finland.

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http://dx.doi.org/10.1016/s0925-4773(02)00014-xDOI Listing
June 2002

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

J Biol Chem 2002 Jun 15;277(25):23092-9. Epub 2002 Apr 15.

Collagen Research Unit, Biocenter and Department of Medical Biochemistry and Molecular Biology, University of Oulu, Aapistie 7, FIN-90220 Oulu, Finland.

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http://dx.doi.org/10.1074/jbc.M107583200DOI Listing
June 2002