Tahmineh Akbarzadeh

Department of Medicinal Chemistry, Faculty of Pharmacy and Drug Design & Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.

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December 2020

Design and Synthesis of Novel Arylisoxazole-Chromenone Carboxamides: Investigation of Biological Activities Associated with Alzheimer's Disease.

Authors:

Mina Saeedi Arezoo Rastegari Roshanak Hariri Seyedeh Sara Mirfazli Mohammad Mahdavi Najmeh Edraki Omidreza Firuzi Tahmineh Akbarzadeh

Chem Biodivers 2020 May 15;17(5):e1900746. Epub 2020 Apr 15.

Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, 14155, Tehran, Iran.

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May 2020

Design, synthesis, in vitro, and in silico studies of novel diarylimidazole-1,2,3-triazole hybrids as potent α-glucosidase inhibitors.

Authors:

Mina Saeedi Maryam Mohammadi-Khanaposhtani Mohammad Sadegh Asgari Nafiseh Eghbalnejad Somaye Imanparast Mohammad Ali Faramarzi Bagher Larijani Mohammad Mahdavi Tahmineh Akbarzadeh

Bioorg Med Chem 2019 12 15;27(23):115148. Epub 2019 Oct 15.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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December 2019

Novel N-benzylpyridinium moiety linked to arylisoxazole derivatives as selective butyrylcholinesterase inhibitors: Synthesis, biological evaluation, and docking study.

Authors:

Fahimeh Vafadarnejad Elahe Karimpour-Razkenari Bilqees Sameem Mina Saeedi Omidreza Firuzi Najmeh Edraki Mohammad Mahdavi Tahmineh Akbarzadeh

Bioorg Chem 2019 11 10;92:103192. Epub 2019 Aug 10.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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November 2019

Design, synthesis, in vivo, and in silico evaluation of new coumarin-1,2,4-oxadiazole hybrids as anticonvulsant agents.

Authors:

Maryam Mohammadi-Khanaposhtani Nematollah Ahangar Sepideh Sobhani Patrick Honarchian Masihi Aidin Shakiba Mina Saeedi Tahmineh Akbarzadeh

Bioorg Chem 2019 08 18;89:102989. Epub 2019 May 18.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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August 2019

Design, synthesis, biological evaluation, and molecular dynamics of novel cholinesterase inhibitors as anti-Alzheimer's agents.

Authors:

Reza Shamsimeymandi Yaghoub Pourshojaei Khalil Eskandari Maryam Mohammadi-Khanaposhtani Ardavan Abiri Arash Khodadadi Amin Langarizadeh Fariba Sharififar Bagher Amirheidari Tahmineh Akbarzadeh Hania Lotfian Alireza Foroumadi Ali Asadipour

Arch Pharm (Weinheim) 2019 Jul 28;352(7):e1800352. Epub 2019 May 28.

Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutics Research Center, Kerman University of Medical Sciences, Kerman, Iran.

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July 2019

, a Bioactive Essential Oil: Chemical Composition and Biological Activities.

Authors:

Mahdieh Eftekhari Mohammad Reza Shams Ardekani Mohsen Amin Farideh Attar Tahmineh Akbarzadeh Maliheh Safavi Elahe Karimpour-Razkenari Mohsen Amini Murray Isman Mahnaz Khanavi

Iran J Pharm Res 2019 ;18(1):412-421

Department of Pharmacognosy, Faculty of Pharmacy and Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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January 2019

Design, synthesis, in vivo and in vitro studies of 1,2,3,4-tetrahydro-9H-carbazole derivatives, highly selective and potent butyrylcholinesterase inhibitors.

Authors:

Roshanak Ghobadian Roghaieh Esfandyari Hamid Nadri Alireza Moradi Mohammad Mahdavi Tahmineh Akbarzadeh Hossein Khaleghzadeh-Ahangar Najmeh Edraki Mohammad Sharifzadeh Mohsen Amini

Mol Divers 2020 Feb 29;24(1):211-223. Epub 2019 Mar 29.

Department of Medicinal Chemistry, Faculty of Pharmacy, and Drug Design & Development Research Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran.

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February 2020

Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents.

Authors:

Mohammad Mahdavi Roshanak Hariri Seyedeh Sara Mirfazli Hania Lotfian Arezoo Rastergari Omidreza Firuzi Najmeh Edraki Bagher Larijani Tahmineh Akbarzadeh Mina Saeedi

Chem Biodivers 2019 Apr 3;16(4):e1800488. Epub 2019 Apr 3.

Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, 1416753955, Iran.

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April 2019

Design and Synthesis of Selective Acetylcholinesterase Inhibitors: Arylisoxazole-Phenylpiperazine Derivatives.

Authors:

Mina Saeedi Dorrin Mohtadi-Haghighi Seyedeh Sara Mirfazli Mohammad Mahdavi Roshanak Hariri Hania Lotfian Najmeh Edraki Aida Iraji Omidreza Firuzi Tahmineh Akbarzadeh

Chem Biodivers 2019 Feb 30;16(2):e1800433. Epub 2019 Jan 30.

Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, 14155 Tehran, Iran.

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February 2019

Design, synthesis and anti-Alzheimer's activity of novel 1,2,3-triazole-chromenone carboxamide derivatives.

Authors:

Arezoo Rastegari Hamid Nadri Mohammad Mahdavi Alireza Moradi Seyedeh Sara Mirfazli Najmeh Edraki Farshad Homayouni Moghadam Bagher Larijani Tahmineh Akbarzadeh Mina Saeedi

Bioorg Chem 2019 03 30;83:391-401. Epub 2018 Oct 30.

Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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March 2019

Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer's compounds: In vitro and in vivo biological evaluation and docking study.

Authors:

Zahra Najafi Mohammad Mahdavi Mina Saeedi Elahe Karimpour-Razkenari Najmeh Edraki Mohammad Sharifzadeh Mahnaz Khanavi Tahmineh Akbarzadeh

Bioorg Chem 2019 03 28;83:303-316. Epub 2018 Oct 28.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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March 2019

Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study.

Authors:

Mina Saeedi Maryam Mohammadi-Khanaposhtani Parvaneh Pourrabia Nima Razzaghi Reza Ghadimi Somaye Imanparast Mohammad Ali Faramarzi Fatemeh Bandarian Ensieh Nasli Esfahani Maliheh Safavi Hossein Rastegar Bagher Larijani Mohammad Mahdavi Tahmineh Akbarzadeh

Bioorg Chem 2019 03 11;83:161-169. Epub 2018 Oct 11.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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March 2019

Facile access to new pyrido[2,3-d]pyrimidine derivatives.

Authors:

Aseyeh Ghaedi Ghasem Rezanejade Bardajee Ahmad Mirshokrayi Mohammad Mahdavi Tahmineh Akbarzadeh

Mol Divers 2019 May 20;23(2):333-340. Epub 2018 Sep 20.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

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May 2019

Design, synthesis, and biological evaluation of selective and potent Carbazole-based butyrylcholinesterase inhibitors.

Authors:

Roshanak Ghobadian Hamid Nadri Alireza Moradi Syed Nasir Abbas Bukhari Mohammad Mahdavi Mehdi Asadi Tahmineh Akbarzadeh Hossein Khaleghzadeh-Ahangar Mohammad Sharifzadeh Mohsen Amini

Bioorg Med Chem 2018 09 29;26(17):4952-4962. Epub 2018 Aug 29.

Department of Medicinal Chemistry, Faculty of Pharmacy, and Drug Design & Development Reseach Center, The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran 14176, Iran. Electronic address:

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September 2018

Novel tetrahydrocarbazole benzyl pyridine hybrids as potent and selective butryl cholinesterase inhibitors with neuroprotective and β-secretase inhibition activities.

Authors:

Roshanak Ghobadian Mohammad Mahdavi Hamid Nadri Alireza Moradi Najmeh Edraki Tahmineh Akbarzadeh Mohammad Sharifzadeh Syed Nasir Abbas Bukhari Mohsen Amini

Eur J Med Chem 2018 Jul 23;155:49-60. Epub 2018 May 23.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14176, Iran. Electronic address:

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July 2018

Synthesis of New Benzimidazole-1,2,3-triazole Hybrids as Tyrosinase Inhibitors.

Authors:

Mohammad Mahdavi Arsalan Ashtari Mahsima Khoshneviszadeh Sara Ranjbar Ameneh Dehghani Tahmineh Akbarzadeh Bagher Larijani Mehdi Khoshneviszadeh Mina Saeedi

Chem Biodivers 2018 Jul 21;15(7):e1800120. Epub 2018 Jun 21.

Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, P.O. Box 14155, 6451, Tehran, Iran.

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July 2018

Design and synthesis of novel coumarin-pyridinium hybrids: In vitro cholinesterase inhibitory activity.

Authors:

Fahimeh Vafadarnejad Mohammad Mahdavi Elahe Karimpour-Razkenari Najmeh Edraki Bilqees Sameem Mahnaz Khanavi Mina Saeedi Tahmineh Akbarzadeh

Bioorg Chem 2018 04 31;77:311-319. Epub 2018 Jan 31.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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April 2018

Chemodiversity of Nepeta menthoides Boiss. & Bohse. essential oil from Iran and antimicrobial, acetylcholinesterase inhibitory and cytotoxic properties of 1,8-cineole chemotype.

Authors:

Niloofar Kahkeshani Abbas Hadjiakhoondi Latifeh Navidpour Tahmineh Akbarzadeh Malihe Safavi Elahe Karimpour-Razkenari Mahnaz Khanavi

Nat Prod Res 2018 Nov 15;32(22):2745-2748. Epub 2017 Oct 15.

a Faculty of Pharmacy and Medicinal Plants Research Centre, Department of Pharmacognosy , Tehran University of Medical Sciences , Tehran , Iran.

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November 2018

In vitro cholinesterase inhibitory activity of some plants used in Iranian traditional medicine.

Authors:

Mina Saeedi Khatereh Babaie Elahe Karimpour-Razkenari Mahdi Vazirian Tahmineh Akbarzadeh Mahnaz Khanavi Mannan Hajimahmoodi Mohammad Reza Shams Ardekani

Nat Prod Res 2017 Nov 6;31(22):2690-2694. Epub 2017 Mar 6.

b Persian Medicine and Pharmacy Research Center , Tehran University of Medical Sciences , Tehran , Iran.

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November 2017

Synthesis of novel chromenones linked to 1,2,3-triazole ring system: Investigation of biological activities against Alzheimer's disease.

Authors:

Mina Saeedi Maliheh Safavi Elahe Karimpour-Razkenari Mohammad Mahdavi Najmeh Edraki Farshad Homayouni Moghadam Mahnaz Khanavi Tahmineh Akbarzadeh

Bioorg Chem 2017 02 24;70:86-93. Epub 2016 Nov 24.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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February 2017

Novel Tacrine-Based Pyrano[3',4':5,6]pyrano[2,3-b]quinolinones: Synthesis and Cholinesterase Inhibitory Activity.

Authors:

Roshanak Hariri Zahra Afshar Mohammad Mahdavi Maliheh Safavi Mina Saeedi Zahra Najafi Reyhaneh Sabourian Elahe Karimpour-Razkenari Najmeh Edraki Farshad Homayouni Moghadam Abbas Shafiee Mahnaz Khanavi Tahmineh Akbarzadeh

Arch Pharm (Weinheim) 2016 Dec 7;349(12):915-924. Epub 2016 Nov 7.

Faculty of Pharmacy, Department of Medicinal Chemistry, Tehran University of Medical Sciences, Tehran, Iran.

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December 2016

Novel tacrine-1,2,3-triazole hybrids: In vitro, in vivo biological evaluation and docking study of cholinesterase inhibitors.

Authors:

Zahra Najafi Mohammad Mahdavi Mina Saeedi Elahe Karimpour-Razkenari Raymond Asatouri Fahimeh Vafadarnejad Farshad Homayouni Moghadam Mahnaz Khanavi Mohammad Sharifzadeh Tahmineh Akbarzadeh

Eur J Med Chem 2017 Jan 8;125:1200-1212. Epub 2016 Nov 8.

Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

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January 2017

Synthesis and biological evaluation of novel imidazopyrimidin-3-amines as anticancer agents.

Authors:

Mohammad Mahdavi Shima Dianat Behnaz Khavari Setareh Moghimi Mohammad Abdollahi Maliheh Safavi Arash Mouradzadegun Sussan Kabudanian Ardestani Reyhaneh Sabourian Saeed Emami Tahmineh Akbarzadeh Abbas Shafiee Alireza Foroumadi

Chem Biol Drug Des 2017 05 29;89(5):797-805. Epub 2016 Dec 29.

Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.

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May 2017

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