Publications by authors named "Tahir Shamsi"

100Publications

Emerging Anti-Microbial Resistance in Febrile Neutropenia: Is it high time to evaluate quality control measures?

Pak J Med Sci 2020 Sep-Oct;36(6):1246-1251

Tahir Shamsi, (FRCPath) Department of Hematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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September 2020

Seroprevalence of anti-SARS-CoV-2 antibodies in residents of Karachi-challenges in acquiring herd immunity for COVID 19.

J Public Health (Oxf) 2020 Sep 17. Epub 2020 Sep 17.

Department of Haematology, National Institute of Blood Diseases and Bone Marrow Transplant, Karachi 75300, Pakistan.

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September 2020

Seasonal variations in hematological disorders: A 10-year single-center experience.

Int J Lab Hematol 2021 Feb 15;43(1):93-98. Epub 2020 Sep 15.

National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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February 2021

Seroprevalence of SARS-CoV-2 antibodies among healthy blood donors in Karachi, Pakistan.

Transfus Apher Sci 2020 Dec 24;59(6):102923. Epub 2020 Aug 24.

Clinical Haematology Departments at National Institute of Blood Diseases & Bone Marrow Transplantation, Karachi, Pakistan.

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December 2020

Novel Genetic Variations in Acute Myeloid Leukemia in Pakistani Population.

Front Genet 2020 23;11:560. Epub 2020 Jun 23.

Department of Hematology, National Institute of Blood Diseases and Bone Marrow Transplantation Karachi, Karachi, Pakistan.

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June 2020

Peripheral Blood Stem Cell Harvest HPC Count Is an Effective Surrogate Marker for CD34+ Cell Count in Allogeneic Stem Cell Transplant Setting.

Transl Oncol 2020 Jul 11;13(7):100788. Epub 2020 May 11.

Clinical Haematology, National Institute of Blood Disease and Bone Marrow Transplantation, ST, 2/A Block 17 Gulshan-e-Iqbal KDA Scheme 24, Karachi, 75300, Pakistan; Bone Marrow Transplantation, National Institute of Blood Disease and Bone Marrow Transplantation, ST, 2/A Block 17 Gulshan-e-Iqbal KDA Scheme 24, Karachi, 75300, Pakistan. Electronic address:

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July 2020

MERGE: A Multinational, Multicenter Observational Registry for Myeloproliferative Neoplasms in Asia, including Middle East, Turkey, and Algeria.

Cancer Med 2020 07 30;9(13):4512-4526. Epub 2020 Apr 30.

Sir YK Pao Centre for Cancer & Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR.

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July 2020

Case report of one month and 15 days old baby with type V hyperlipoproteinemia (HLP).

BMC Endocr Disord 2020 Feb 11;20(1):22. Epub 2020 Feb 11.

Department of Pathology, National Institute of Blood disease and Bone Marrow Transplantation (NIBD), ST 2/A Block 17 Gulshan-e-iqbal KDA Scheme 24, Karachi, 74800, Pakistan.

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February 2020

Coagulation abnormalities in dengue and dengue haemorrhagic fever patients.

Transfus Med 2020 Feb 19;30(1):46-50. Epub 2019 Dec 19.

Department of Hematology, Hemostasis & Thrombosis, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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February 2020

Cell Population Data-Driven Acute Promyelocytic Leukemia Flagging Through Artificial Neural Network Predictive Modeling.

Transl Oncol 2020 Jan 13;13(1):11-16. Epub 2019 Nov 13.

Post-graduate Institute of Life Sciences, National Institute of Blood Disease (NIBD), Karachi, Pakistan.

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January 2020

A Novel Nonsense Mutation in Causes LAD-III in a Pakistani Family.

Front Genet 2019 24;10:360. Epub 2019 Apr 24.

Department of Clinical Hematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.

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April 2019

Pattern of Antimicrobial Sensitivity in Microbiologically Documented Infections in Neutropenic Patients with Haematological Malignancies: A single Center Study.

Indian J Microbiol 2019 Jun 4;59(2):188-192. Epub 2019 Mar 4.

1Department of Clinical Haematology and BMT, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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June 2019

Hydroxyurea (hydroxycarbamide) for transfusion-dependent β-thalassaemia.

Cochrane Database Syst Rev 2019 03 16;3:CD012064. Epub 2019 Mar 16.

Department of Pediatric Hematology and Oncology, National Institute of Blood Disease & Bone Marrow Transplant, ST 2/A Block 17 Gulshan-e-Iqbal, KDA Scheme 24, Karachi, Sindh, Pakistan, 75300.

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March 2019

Early and sustained deep molecular response achieved with nilotinib in high Sokal risk chronic myeloid leukemia patients.

Cancer Manag Res 2019 15;11:1493-1502. Epub 2019 Feb 15.

Department of Clinical Hematology, National Institute of Blood Diseases & Bone Marrow Transplantation, Karachi, Pakistan,

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February 2019

Homozygous CALR Mutation in Primary Myelofibrosis and Its Effect on Disease Phenotype: A Case Report and Review of the Literature.

Case Rep Hematol 2019 20;2019:1430170. Epub 2019 Jan 20.

Department of Clinical Haematology, National Institute of Blood Diseases & Bone Marrow Transplantation, P.O. Box-75300, Karachi, Pakistan.

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January 2019

Lung resistance-related protein (LRP) predicts favorable therapeutic outcome in Acute Myeloid Leukemia.

Sci Rep 2019 01 23;9(1):378. Epub 2019 Jan 23.

Jinnah Medical and Dental College, Karachi, Pakistan.

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January 2019

Gene expression of , , , and topoisomerase IIα as an indicator of chemotherapy response in AML treated with cytarabine and daunorubicin.

Cancer Manag Res 2018 9;10:5573-5589. Epub 2018 Nov 9.

Department of Pharmacology, Jinnah Medical and Dental College, Karachi, Pakistan.

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November 2018

Establishment of diagnostic facilities for autosomal recessive bleeding disorders in Pakistan.

Blood Adv 2018 11;2(Suppl 1):35-38

Department of Pathology and Clinical Hematology, National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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November 2018

Evaluation of efficacy of serological methods for detection of HCV infection in blood donors: A single centre experience.

Pak J Med Sci 2018 Sep-Oct;34(5):1204-1208

Tahir Sultan Shamsi, FRC Path. National Institute of Blood Diseases & Bone Marrow Transplantation, Karachi, Pakistan.

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October 2018

Alteration of Serum Free Fatty Acids are Indicators for Progression of Pre-leukaemia Diseases to Leukaemia.

Sci Rep 2018 10 5;8(1):14883. Epub 2018 Oct 5.

H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.

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October 2018

Challenges in managing graft-versus-host disease in developing countries: a perspective.

Bone Marrow Transplant 2019 05 20;54(5):641-647. Epub 2018 Sep 20.

Oncology Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

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May 2019

Laboratory diagnosis for thalassemia intermedia: Are we there yet?

J Clin Lab Anal 2019 Jan 17;33(1):e22647. Epub 2018 Sep 17.

Department of Haematology, National Institute of Blood Diseases & BMT, Karachi, Pakistan.

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January 2019

Pharmacoproteomics Profiling of Plasma From β-Thalassemia Patients in Response to Hydroxyurea Treatment.

J Clin Pharmacol 2019 01 27;59(1):98-106. Epub 2018 Aug 27.

National Center for Proteomics, University of Karachi, Karachi, Pakistan.

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January 2019

Complex Karyotype in Hematological Diseases: A 6-Year Single Centre Study from Pakistan.

J Oncol 2018 3;2018:2019239. Epub 2018 Jun 3.

National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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June 2018

Application of the ISTH bleeding score in hemophilia.

Transfus Apher Sci 2018 Aug 15;57(4):556-560. Epub 2018 Jun 15.

Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada; School of Baccalaureate Nursing, St Lawrence College, Kingston, Ontario, Canada.

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August 2018

Clinical presentation of acute myeloid leukaemia - A decade-long institutional follow-up.

J Pak Med Assoc 2017 Dec;67(12):1837-1842

(Retired) Dow International Medical College, Karachi, Pakistan.

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December 2017

5D proteomic approach for the biomarker search in plasma: Acute myeloid leukaemia as a case study.

Sci Rep 2017 11 27;7(1):16440. Epub 2017 Nov 27.

Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Science, University of Karachi, Karachi, 75270, Pakistan.

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November 2017

Recent advances in diagnostic and prognostic aspects of acute myeloid leukaemia.

J Pak Med Assoc 2017 Oct;67(10):1580-1587

Retired Professor of Biochemistry, Dow International Medical College, Karachi, Pakistan.

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October 2017

Diagnosis and phenotypic assessment of Pakistani Haemophilia B carriers.

Pak J Med Sci 2017 May-Jun;33(3):738-742

Dr. Abid Sohail Taj, PhD, MRC (Path), National Institute of Blood Diseases & Bone Marrow Transplantation, Karachi, Pakistan.

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August 2017

Mutation Spectrum and Genotype-Phenotype Analyses in a Pakistani Cohort With Hemophilia B.

Clin Appl Thromb Hemost 2018 Jul 28;24(5):741-748. Epub 2017 Jul 28.

1 Hematology Department, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.

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July 2018

Genomic profile of a patient with triple negative essential thrombocythemia, unresponsive to therapy: A case report and literature review.

J Adv Res 2017 Jul 19;8(4):375-378. Epub 2017 Apr 19.

Department of Clinical Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, P.O. Box 75300, Pakistan.

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July 2017

Alpha thalassemia deletions found in suspected cases of beta thalassemia major in Pakistani population.

Pak J Med Sci 2017 Mar-Apr;33(2):411-416

Tahir Shamsi, FRC Path. Department of Hematology, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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May 2017

Clinicohematological and cytogenetic profile of myelodysplastic syndromes in Pakistan-compare and contrast.

Mol Cytogenet 2017 8;10:17. Epub 2017 May 8.

National Institute of Blood Disease and Bone Marrow Transplantation (NIBD), St 2/A block 17 Gulshan-e-Iqbal KDA scheme 24, Karachi, Pakistan.

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May 2017

Laboratory Diagnosis of Malaria: Comparison of Manual and Automated Diagnostic Tests.

Can J Infect Dis Med Microbiol 2017 5;2017:9286392. Epub 2017 Apr 5.

National Institute of Blood Diseases & Bone Marrow Transplantation, ST 2/A Block 17, Gulshan-e-Iqbal KDA Scheme 24, Karachi, Pakistan.

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April 2017

Autosomal recessive inherited bleeding disorders in Pakistan: a cross-sectional study from selected regions.

Orphanet J Rare Dis 2017 04 7;12(1):66. Epub 2017 Apr 7.

Department of Thrombosis and Hemostasis, National Institute of Blood Diseases and Bone Marrow Transplantation, ST 2/A, Block 17, Gulshan-e-Iqbal, KDA Scheme 24, Karachi, Pakistan.

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April 2017

Trends of ABO and Rh phenotypes in transfusion-dependent patients in Pakistan.

Immunohematology 2016 Dec;32(4):170-173

Department of Hematology of National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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December 2016

Outcomes of 1st Remission Induction Chemotherapy in Acute Myeloid Leukemia Cytogenetic Risk Groups

Asian Pac J Cancer Prev 2016 12 1;17(12):5251-5256. Epub 2016 Dec 1.

National Institute of Blood Disease and Bone Marrow Transplantation, |Department of Pharmacology, Faculty of Pharmacy,University of Karachi, Pakistan. Email:

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December 2016

Ring Chromosome 10 in a Case of Acute Promyelocytic Leukemia.

J Coll Physicians Surg Pak 2016 Nov;26(11):941-942

Department of Pathology, National Institute of Blood Disease and BMT, Karachi.

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November 2016

Prevalence of transfusion transmissible infections in blood donors of Pakistan.

BMC Hematol 2016 18;16:27. Epub 2016 Nov 18.

Department of Blood Bank of National Institute of Blood Disease and Bone Marrow Transplantation (NIBD), St 2/A block 17 Gulshan-e-Iqbal KDA scheme 24, Karachi, Pakistan.

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November 2016

Environmental determinants of aplastic anemia in Pakistan: a case-control study.

Z Gesundh Wiss 2016 11;24(5):453-460. Epub 2016 Jun 11.

Department of Clinical Hematology, National Institute of Blood Disease Center and Bone Marrow Transplantation, Karachi, Pakistan.

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June 2016

Serum metabonomics of acute leukemia using nuclear magnetic resonance spectroscopy.

Sci Rep 2016 08 2;6:30693. Epub 2016 Aug 2.

Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan.

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August 2016

Coexisting JAK2V617F and CALR Exon 9 Mutation in Essential Thrombocythemia.

Indian J Hematol Blood Transfus 2016 Jun 9;32(Suppl 1):112-116. Epub 2016 Feb 9.

Department of Postgraduate Studies and Research, National Institute of Blood Disease and Bone Marrow Transplantation, ST-2/A, Block 17 Gulshan e Iqbal, KDA Scheme 24, Karachi, 75300 Pakistan.

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June 2016

Importance of immature platelet fraction as predictor of immune thrombocytopenic purpura.

Pak J Med Sci 2016 May-Jun;32(3):575-9

Tahir Sultan Shamsi, FRCPath. National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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July 2016

SERUM metabolomics of acute lymphoblastic leukaemia and acute myeloid leukaemia for probing biomarker molecules.

Hematol Oncol 2017 Dec 10;35(4):769-777. Epub 2016 Jun 10.

National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan.

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December 2017

Outcome of Inversion 16 in TKD Positive and Negative Acute Myeloid Leukemia Patients.

Asian Pac J Cancer Prev 2016 ;17(4):2343-4

Department of Molecular Genetics NIBD Postgraduate Institute of Life Sciences, Karachi, Pakistan E-mail :

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January 2017

Coexisting JAK2V617F and CALR Exon 9 Mutations in Myeloproliferative Neoplasms - Do They Designate a New Subtype?

Asian Pac J Cancer Prev 2016 ;17(3):923-6

Department of Postgraduate Studies and Research, National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan E-mail :

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January 2017

Chronic Myeloid Leukemia--Prognostic Value of Mutations.

Asian Pac J Cancer Prev 2015 ;16(17):7415-23

Haematology, Medical Sciences, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan E-mail :

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September 2016

Survival outcome of AML patients with and without TKD mutations.

Asian Pac J Cancer Prev 2014 ;15(24):10995

Department of Molecular Genetics, NIBD Postgraduate Institute of Life Sciences Karachi, Pakistan E-mail :

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October 2015

Clinical and molecular characterisation of 21 patients affected by quantitative fibrinogen deficiency.

Thromb Haemost 2015 Mar 27;113(3):567-76. Epub 2014 Nov 27.

Prof. Stefano Duga, PhD, Department of Medical Biotechnology and Translational Medicine, University of Milan, Via Viotti 3/5, 20133 Milan, Italy, Tel.: +39 02 50315823, Fax: +39 02 50315864, E-mail:

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March 2015

Epidemiologic and HLA antigen profile in patients with aplastic anemia.

J Coll Physicians Surg Pak 2014 Aug;24(8):549-52

Department of Clinical Hematology, National Institute of Blood Disease Centre and Bone Marrow Transplantation(NIBD and BMT), Karachi.

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August 2014

Prognostic involvement of nucleophosmin mutations in acute myeloid leaukemia.

Asian Pac J Cancer Prev 2013 ;14(10):5615-20

Molecular Biology, Pure and Applied Research, National Institute Blood Diseases and Bone Marrow Transplantation, Karachi, Pakistan E-mail :

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January 2015

Oxidative stress and total antioxidant status in acute leukemia at diagnosis and post remission induction phase.

Pak J Pharm Sci 2013 Nov;26(6):1123-30

Department of Hematology, 2Department of Clinical Hematology and Oncology, 3Research Laboratory, National Institute of Blood Disease and Bone Marrow Transplantation, Karachi, Pakistan.

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November 2013

Molecular epidemiology of β-thalassemia in Pakistan: Far reaching implications.

Indian J Hum Genet 2012 May;18(2):193-7

Department of Pediatric Hematology & Molecular Medicine, National Institute of Blood Diseases, Karachi, Pakistan.

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May 2012

Successful Management of Acute Catastrophic Juvenile Vaginal Bleeding in Glanzmann's Thromboasthenia by Uterine Tamponade: A Case Report and Review of The Literature.

Case Rep Hematol 2012 20;2012:530908. Epub 2012 Mar 20.

Department of Obstetrics & Gynecology Unit 3, Dow University of Health Sciences, Baba-e-Urdu Road, Karachi 74200, Pakistan.

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August 2012

Thrombophilia investigation in Pakistani women with recurrent pregnancy loss.

J Obstet Gynaecol Res 2013 Jan 13;39(1):121-5. Epub 2012 Jun 13.

Departments of Obstetrics and Gynecology Unit 2 Biostatistics, Dow University of Health Sciences National Institute of Blood Diseases, Karachi, Pakistan.

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January 2013

Frequency of factor VIII (FVIII) inhibitor in haemophilia A.

J Coll Physicians Surg Pak 2012 May;22(5):289-93

Department of Haemostasis and Thrombosis, National Institute of Blood Disease & Bone Marrow Transplantation, Karachi.

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May 2012

Molecular epidemiology of β-thalassemia in Pakistan: far reaching implications.

Int J Mol Epidemiol Genet 2011 28;2(4):403-8. Epub 2011 Nov 28.

Department of Pediatric Hematology & Molecular Medicine, National Institute of Blood Diseases Karachi, Pakistan.

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October 2012

JAK2V617F mutation in chronic myeloid leukemia predicts early disease progression.

J Coll Physicians Surg Pak 2011 Aug;21(8):472-5

Department of Haematology, National Institute of Blood Diseases and Bone Marrow Transplantation, Karachi.

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August 2011

Efficacy of hydroxyurea in providing transfusion independence in β-thalassemia.

J Pediatr Hematol Oncol 2011 Jul;33(5):339-43

Department of Pediatric Hematology, National Institute of Blood Diseases, Karachi, Pakistan.

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July 2011

Transfusion transmitted infections in patients with hemophilia of Karachi, Pakistan.

Clin Appl Thromb Hemost 2011 Nov-Dec;17(6):651-5. Epub 2011 Mar 14.

Department of Blood Bank & Haemostasis, National Institute of Blood Disease & Bone Marrow Transplantation.

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October 2012

Congenital bleeding disorders in Karachi, Pakistan.

Clin Appl Thromb Hemost 2011 Nov-Dec;17(6):E131-7. Epub 2011 Jan 19.

Department of Haemostasis and Thrombosis, National Institute of Blood Disease and Bone Marrow Transplantation.

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October 2012

Clinical features and types of von Willebrand disease in Karachi.

Clin Appl Thromb Hemost 2011 Nov-Dec;17(6):E102-5. Epub 2010 Dec 15.

Thrombosis & Haemostasis Department of National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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October 2012

Bleeding disorders in the tribe: result of consanguineous in breeding.

Orphanet J Rare Dis 2010 Sep 7;5:23. Epub 2010 Sep 7.

Haemostasis & Thrombosis department of National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan.

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September 2010

Adolescent menorrhagia due to platelet function disorder.

J Pak Med Assoc 2010 Feb;60(2):127-9

Department of Obstetrics & Gynecology Unit-3, Dow University of Health Sciences & Civil Hospital Karachi.

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February 2010

Arteriovenous thrombosis in chronic renal failure patients receiving renal replacement therapy.

J Coll Physicians Surg Pak 2008 Jul;18(7):418-23

Sindh Institute of Urology and Transplantation (SUIT), Karachi.

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July 2008

Triglyceride profile in dyslipidaemia of type 2 diabetes mellitus.

J Coll Physicians Surg Pak 2008 May;18(5):270-3

Department of Biochemistry, Karachi Medical and Dental College, Karachi, Pakistan.

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May 2008

Role of tryptophan in the pathogenesis of hepatic encephalopathy.

J Pak Med Assoc 2008 Feb;58(2):68-70

Department of Biomedical Engineering, Sir Syed University of Engineering Technology, Karachi.

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February 2008

Psychiatric disorders in bone marrow transplant patients.

J Coll Physicians Surg Pak 2007 Feb;17(2):98-100

Department of Psychiatry, National Institute of Child Health/Bismillah Taqee Institute of Health Sciences and Blood Diseases Centre, Karachi.

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February 2007

Role of recombinant activated factor VII in securing haemostatic failure in gun shot trauma.

J Pak Med Assoc 2006 May;56(5):238-41

Bismillah Taqee Institute of Health Sciences and Blood Diseases Centre, Karachi.

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May 2006

Frequency of thrombophilia in patients with adverse pregnancy outcome.

J Pak Med Assoc 2005 Jun;55(6):245-7

Department of Obstetrics and Gynaecology, Unit 2, Civil Hospital, Karachi.

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June 2005